Bile acids trigger GLP-1 release predominantly by accessing basolaterally located G protein-coupled bile acid receptors

Endocrinology

Volumn 156, Issue 11, 2015, Pages 3961-3970

  Brighton, Cheryl A ^a   Rievaj, Juraj ^a   Kuhre, Rune E ^b   Glass, Leslie L ^a   Schoonjans, Kristina ^c   Holst, Jens J ^b   Gribble, Fiona M ^a   Reimann, Frank ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b Capital Region   (Denmark)

^c EPFL   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

BILE ACID; CALCIUM ION; CYCLIC AMP; G PROTEIN COUPLED BILE ACID RECEPTOR 1; G PROTEIN COUPLED RECEPTOR; GLUCAGON LIKE PEPTIDE 1; TAUROCHOLIC ACID; TAURODEOXYCHOLIC ACID; TAUROLITHOCHOLIC ACID; UNCLASSIFIED DRUG; CALCIUM; GPBAR1 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CALCIUM CELL LEVEL; CONTROLLED STUDY; INTESTINE EPITHELIUM; L CELL LINE; MOUSE; NONHUMAN; PRIORITY JOURNAL; ANIMAL; CELL CULTURE; DRUG EFFECTS; ENTEROENDOCRINE CELL; FLUORESCENCE MICROSCOPY; GENETICS; INTRACELLULAR SPACE; KNOCKOUT MOUSE; MALE; METABOLISM; SECRETION (PROCESS); SMALL INTESTINE; TISSUE CULTURE TECHNIQUE; TRANSGENIC MOUSE; WISTAR RAT;

ANIMALS; BILE ACIDS AND SALTS; CALCIUM; CELLS, CULTURED; CYCLIC AMP; ENTEROENDOCRINE CELLS; GLUCAGON-LIKE PEPTIDE 1; INTESTINE, SMALL; INTRACELLULAR SPACE; MALE; MICE, KNOCKOUT; MICE, TRANSGENIC; MICROSCOPY, FLUORESCENCE; RATS, WISTAR; RECEPTORS, G-PROTEIN-COUPLED; TAURODEOXYCHOLIC ACID; TAUROLITHOCHOLIC ACID; TISSUE CULTURE TECHNIQUES;

EID: 84946071276     PISSN: 00137227     EISSN: 19457170     Source Type: Journal    
DOI: 10.1210/en.2015-1321     Document Type: Article

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