Effects on gastric mucosa induced by dental bleaching – An experimental study with 6% hydrogen peroxide in rats

Journal of Applied Oral Science

Volumn 23, Issue 5, 2015, Pages 497-507

  Paula, Anabela Baptista ^a   Dias, Maria Isabel ^b   Ferreira, Manuel Marques ^a   Carrilho, Teresa ^a   Marto, Carlos Miguel ^a   Casalta, João ^a   Cabrita, António Silvério ^a   Carrilho, Eunice ^a  

^a UNIVERSITY OF COIMBRA   (Portugal)

^b UNIVERSITY OF TRÁS OS MONTES AND ALTO DOURO   (Portugal)

Author keywords

Ambulatory monitoring; Bleaching agents; Gastritis; Hydrogen peroxide; Tooth bleaching; Toxicity

Indexed keywords

ALCOHOL; HYDROGEN PEROXIDE; TOOTH BLEACHING AGENT;

ADVERSE EFFECTS; ANIMAL; BODY WEIGHT; DENTAL PROCEDURE; DRUG EFFECTS; EVALUATION STUDY; ORGAN SIZE; PATHOLOGY; SPLEEN; STOMACH MUCOSA; TIME FACTOR; WISTAR RAT;

ANIMALS; BODY WEIGHT; ETHANOL; GASTRIC MUCOSA; HYDROGEN PEROXIDE; ORGAN SIZE; RATS, WISTAR; SPLEEN; TIME FACTORS; TOOTH BLEACHING; TOOTH BLEACHING AGENTS;

EID: 84946034722     PISSN: 16787757     EISSN: 16787765     Source Type: Journal    
DOI: 10.1590/1678-775720150235     Document Type: Article

References (30)

1. Adam-Rodwell G, Kong BM, Bagley DM, Tonucci D, Christina LM. Safety profile of Colgate Platinum Professional Toothwhitening System. Compend Suppl. 1994;17:S622-66.
2. Birdane FM, Cemek M, Birdane YO, Gülçin I, Büyükokuroglu ME. Beneficial effects of Foeniculum vulgare on ethanol-induced acute gastric mucosal injury in rats. World J Gastroenterol. 2007;13(4):607-11.
3. Cantürk NZ, Cantürk Z, Özbilim G, Yenisey C. Protective effect of vitamin E on gastric mucosal injury in rats with biliary obstruction. Can J Gastroenterol. 2000;14(6):499-503.
4. Cherry DV, Bowers DE Jr, Thomas L, Redmond AF. Acute toxicological effects of ingested tooth whiteners in female rats. J Dent Res. 1993;72:1298-303.
5. Dahl JE, Becher R. Acute toxicity of carbamide peroxide and a commercially available tooth-bleaching agent in rats. J Dent Res. 1995;74:710-4.
6. Dahl JE, Pallesen U. Tooth bleaching – a critical review of the biological aspects. Crit Rev Oral Biol Med. 2003;14:292-304.
7. Demarco FF, Meireles SS, Masotti AS. Over-the-counter whitening agents: A concise review. Braz Oral Res. 2009;23:64-70.
8. Fearon J. Tooth whitening: concepts and controversies. J Ir Dent Assoc. 2007;53:132-40.
9. Gambarini G, Testarelli L, Luca MD, Dolci G. Effiacy and safety assessment of a new liquid tooth whitening gel containing 5.9% hydrogen peroxide. Am J Dent. 2004;17(2):75-9.
10. Gerlach RW, Barker ML. Randomized clinical trial comparing overnight use of two self-directed peroxide tooth whiteners. Am J Dent. 2003;16:17B-21B.
11. Gökay O, Müjdeci A, Algn E. Peroxide penetration into the pulp from whitening strips. J Endod. 2004;30:887-9.
12. Goldberg M, Grootveld M, Lynch E. Undesirable and adverse effects of tooth-whitening products: A review. Clin Oral Invest. 2010;14:1-10.
13. Haywood VB. New bleaching considerations compared with at-home bleaching. J Esthet Restor Dent. 2003;15:184-7.
14. Haywood VB, Leonard RH, Nelson CF, Brunson WD. Effectiveness, side effects and long-term status of nightguard vital bleaching. J Am Dent Assoc. 1994;125:1219-26.
15. Hernández-Muñoz R, Montiel-Ruíz C, Vázquez-Martínez O. Gastric mucosal cell proliferation in ethanol-induced chronic mucosal injury is related to oxidative stress and lipid peroxidation in rats. Lab Invest. 2000;80:1161-9.
16. Kelleher MG, Roe FJ. The safety-in-use 10% carbamide peroxide (Opalescence) for bleaching teeth under the supervision of a dentist. Br Dent J. 1999;187:190-4.
17. Kugel G, Kastali S. Tooth-whitening efficacy and safety: A randomized and controlled clinical trial. Compend Contin Educ Dent Suppl. 2000;21:S16-S21.
18. Li Y. Biological properties of peroxide-containing tooth whiteners. Food Chem Toxicol. 1996;34:887-904.
19. Li Y. Toxicological considerations of tooth bleaching using peroxide-containing agents. J Am Dent Assoc. 1997;128:31S-36S.
20. Li Y. The safety of peroxide-containing at-home tooth whiteners. Compend COntin Educ Dent. 2003;4A:384-9.
21. Matis BA, Wang Y, Eckert GJ, Cochran MA, Jiang T. Extended bleaching of tetracicline-stained teeth: A 5-year study. Oper Dent. 2006;31:643-51.
22. Minoux M, Serfaty R. Vital tooth bleaching: Biologic adverse effects – a review. Quintessence Int. 2008;39:645-59.
23. Munro IC, Williams GM, Heymann HO, Kroes R. Tooth whitening products and the risk of oral cancer. Food Chem Toxicol. 2006;44:301-15.
24. Niedeman R, Tantrapol MC, Slinin P, Hayes C, Conway S. Effectiveness of dentist-prescribed, home-applied tooth whitening. A meta-analysis. J Contemp Dent Pract. 2000;4:20-36.
25. Pugh G Jr, Zaidel L, Lin N, Stranick M, Bagley D. High levels of hydrogen peroxide in overnight tooth-whitening formulas: effects on enamel and pulp. J Esthet Restor Dent. 2005;17:40-7.
26. Redmond AF, Cherry DV, Bowers DE Jr. Acute illness and recovery in adult female rats following ingestion of a tooth whitener containing 6% hydrogen peroxide. Am J Dent. 1997;10:268-71.
27. Shethri SA, Matis BA, Cochran MA, Zekonis R, Stropes M. A clinical evaluation of two in-office bleaching products. Oper Dent. 2003;28:488-95.
28. Walsh LJ. Safety issues relating to the use of hydrogen peroxide in dentistry. Aust Dent J. 2000;45:257-69.
29. Weiner ML, Freeman C, Trochimowicz H, de Gerlache J, Jacobi S, Malinverno G, et al. 13-week drinking water toxicity study of hydrogen peroxide with 6-week recovery period in catalasedeficient mice. Food Chem Toxicol. 2000;38:607-15.
30. Xiang Z, Si JM, Huang HD. Chronic gastritis rat model and role of inducing factors. World J Gastroenterol. 2004;10:3212-4.