Failure to recognize preoperatively high-risk endometrial carcinoma is associated with a poor outcome

European Journal of Obstetrics and Gynecology and Reproductive Biology

Volumn 194, Issue , 2015, Pages 153-160

  Di Cello, Annalisa ^a   Rania, Erika ^a   Zuccalà, Valeria ^a   Venturella, Roberta ^a   Mocciaro, Rita ^a   Zullo, Fulvio ^a   Morelli, Michele ^a  

^a UNIVERSITY MAGNA GRAECIA OF CATANZARO   (Italy)

Author keywords

Frozen section; High risk endometrial cancer; Poor prognosis; Pre operative diagnoses; Surgical staging; Undiagnosed endometrial cancer

Indexed keywords

ANTINEOPLASTIC AGENT;

ADJUVANT THERAPY; ADULT; ARTICLE; CANCER ADJUVANT THERAPY; CANCER DIAGNOSIS; CANCER PROGNOSIS; CANCER RISK; CANCER STAGING; CANCER SURGERY; CANCER SURVIVAL; COMORBIDITY; COMPARATIVE STUDY; CONTROLLED STUDY; DIAGNOSTIC ERROR; DISEASE FREE SURVIVAL; DISEASE SPECIFIC SURVIVAL; ENDOMETRIUM BIOPSY; ENDOMETRIUM CARCINOMA; FEMALE; FROZEN SECTION; HIGH RISK PATIENT; HISTOLOGY; HUMAN; HYSTERECTOMY; MAJOR CLINICAL STUDY; OVERALL SURVIVAL; PREOPERATIVE EVALUATION; PRIORITY JOURNAL; RECURRENCE FREE SURVIVAL; RETROSPECTIVE STUDY; TREATMENT OUTCOME; AGED; BIOPSY; CANCER GRADING; CARCINOMA; ENDOMETRIAL NEOPLASMS; ENDOMETRIUM; MIDDLE AGED; PATHOLOGY; PREOPERATIVE PERIOD; RISK FACTOR; SURVIVAL RATE;

AGED; BIOPSY; CARCINOMA; DIAGNOSTIC ERRORS; DISEASE-FREE SURVIVAL; ENDOMETRIAL NEOPLASMS; ENDOMETRIUM; FEMALE; HUMANS; MIDDLE AGED; NEOPLASM GRADING; NEOPLASM STAGING; PREOPERATIVE PERIOD; RETROSPECTIVE STUDIES; RISK FACTORS; SURVIVAL RATE;

EID: 84945931068     PISSN: 03012115     EISSN: 18727654     Source Type: Journal    
DOI: 10.1016/j.ejogrb.2015.09.004     Document Type: Article

References (44)

1. C.B. Gilks, E. Oliva, and R.A. Soslow Poor interobserver reproducibility in the diagnosis of high-grade endometrial carcinoma Am J Surg Pathol 37 2013 874 881
2. R. Murali, R.A. Soslow, and B. Weigelt Classification of endometrial carcinoma: more than two types Lancet Oncol 15 2014 e268 e278
3. R. Halperin, S. Zehavi, R. Langer, E. Hadas, I. Bukovsky, and D. Schneider Uterine papillary serous carcinoma (pure and mixed type) compared with moderately and poorly differentiated endometrioid carcinoma. A clinicopathologic study Eur J Gynaecol Oncol 23 2002 300 304
4. W.T. Creasman, M.F. Kohler, F. Odicino, P. Maisonneuve, and P. Boyle Prognosis of papillary serous, clear cell, and grade 3 stage I carcinoma of the endometrium Gynecol Oncol 95 2004 593 596
5. J.C. Schink, J.R. Lurain, C.B. Wallemark, and J.S. Chmiel Tumor size in endometrial cancer: a prognostic factor for lymph node metastasis Obstet Gynecol 70 1987 216 219
6. J.M. Briet, H. Hollema, N. Reesink, and et al. Lymphvascular space involvement: an independent prognostic factor in endometrial cancer Gynecol Oncol 96 2005 799 804
7. K.B. Lee, K.D. Ki, J.M. Lee, and et al. The risk of lymph node metastasis based on myometrial invasion and tumor grade in endometrioid uterine cancers: a multicenter, retrospective Korean study Ann Surg Oncol 16 2009 2882 2887
8. M.R. Milam, J. Java, J.L. Walker, and et al. Nodal metastasis risk in endometrioid endometrial cancer Obstet Gynecol 119 2012 286 292
9. R. Berretta, T.S. Patrelli, C. Migliavacca, and et al. Assessment of tumor size as a useful marker for the surgical staging of endometrial cancer Oncol Rep 31 2014 2407 2412
10. K. Matsuo, N.R. Opper, M.A. Ciccone, and et al. Time interval between endometrial biopsy and surgical staging for type I endometrial cancer: association between tumor characteristics and survival outcome Obstet Gynecol 125 2015 424 433
11. Cancer Genome Atlas Research Network, C. Kandoth, N. Schultz, and et al. Integrated genomic characterization of endometrial carcinoma Nature 497 2013 67 73
12. B. Meng, L.N. Hoang, J.B. McIntyre, and et al. POLE exonuclease domain mutation predicts long progression-free survival in grade 3 endometrioid carcinoma of the endometrium Gynecol Oncol 134 2014 15 19
13. D.N. Church, E. Stelloo, R.A. Nout, and et al. Prognostic significance of POLE proofreading mutations in endometrial cancer J Natl Cancer Inst 107 2014 402
14. W.B. Growdon, J. Groeneweg, V. Byron, and et al. HER2 over-expressing high grade endometrial cancer expresses high levels of p95HER2 variant Gynecol Oncol 2015 pii:S0090-8258(15)00537-5
15. Y. Liu, R.R. Broaddus, and W. Zhang Identifying aggressive forms of endometrioid-type endometrial cancer: new insights into molecular subtyping Expert Rev Anticancer Ther 15 2015 1 3
16. F. Darvishian, A.J. Hummer, H.T. Thaler, and et al. Serous endometrial cancers that mimic endometrioid adenocarcinomas: a clinicopathologic and immunohistochemical study of a group of problematic cases Am J Surg Pathol 28 2004 1568 1578
17. A. Alkushi, Z.H. Abdul-Rahman, P. Lim, and et al. Description of a novel system for grading of endometrial carcinoma and comparison with existing grading systems Am J Surg Pathol 29 2005 295 304
18. A. Alkushi, M. Köbel, S.E. Kalloger, and C.B. Gilks High grade endometrial carcinoma: serous and grade 3 endometrioid carcinomas have different immunophenotypes and outcomes Int J Gynecol Pathol 29 2010 343 350
19. R.A. Soslow, S.L. Wethington, M. Cesari, and et al. Clinicopathologic analysis of matched primary and recurrent endometrial carcinoma Am J Surg Pathol 36 2012 1771 1781
20. S. Chiang, and R.A. Soslow Updates in diagnostic immunohistochemistry in endometrial carcinoma Semin Diagn Pathol 31 2014 205 215
21. S. Kumar, F. Medeiros, S.C. Dowdy, and et al. A prospective assessment of the reliability of frozen section to direct intraoperative decision making in endometrial cancer Gynecol Oncol 127 2012 525 531
22. S. Kumar, A. Mariani, J.N. Bakkum-Gamez, and et al. Risk factors that mitigate the role of paraaortic lymphadenectomy in uterine endometrioid cancer Gynecol Oncol 130 2013 441 445
23. S. Kumar, K.C. Podratz, J.N. Bakkum-Gamez, and et al. Prospective assessment of the prevalence of pelvic, para-aortic and high para-aortic lymph node metastasis in endometrial cancer Gynecol Oncol 132 2014 38 43
24. J.M. Stephan, J. Hansen, M. Samuelson, and et al. Intra-operative frozen section results reliably predict final pathology in endometrial cancer Gynecol Oncol 2014 pii:S0090-8258(14)00811-7
25. M. Frumovitz, B.M. Slomovitz, D.K. Singh, and et al. Frozen section analyses as predictors of lymphatic spread in patients with early-stage uterine cancer J Am Coll Surg 199 2004 388 393
26. C. Celik, S. Ozdemir, H. Esen, O. Balci, and O. Ylmaz The clinical value of preoperative and intraoperative assessments in the management of endometrial cancer Int J Gynecol Cancer 20 2010 358 362
27. P.T. Soliman, M. Frumovitz, W. Spannuth, and et al. Lymphadenectomy during endometrial cancer staging: practice patterns among gynecologic oncologists Gynecol Oncol 119 2010 291 294
28. NCCN guidelines 2014. https://www.nccn.org/store/login/login.aspx?ReturnURL=http://www.nccn.org/professionals/physician-gls/pdf/uterine.pdf.
29. ESMO guidelines. http://www.esmo.org/Guidelines/Gynaecological-Cancers/Endometrial-Cancer.
30. L. Helpman, R. Kupets, A. Covens, and et al. Assessment of endometrial sampling as a predictor of final surgical pathology in endometrial cancer Br J Cancer 110 2014 609 615
31. M.A. Voss, R. Ganesan, L. Ludeman, and et al. Should grade 400 3 endometrioid endometrial carcinoma be considered a type 2 cancer - a clinical and pathological evaluation Gynecol Oncol 124 2012 15 20
32. L.A. Brinton, A.S. Felix, D.S. McMeekin, and et al. Etiologic heterogeneity in endometrial cancer: evidence from a Gynecologic Oncology Group trial Gynecol Oncol 129 2013 277 284
33. H.M. Werner, J. Trovik, J. Marcickiewicz, and et al. A discordant histological risk classification in preoperative and operative biopsy in endometrial cancer is reflected in metastatic risk and prognosis Eur J Cancer 49 February (3) 2013 625 632
34. L.N. Hoang, M.K. McConechy, M. Köbel, and et al. Histotype-genotype correlation in 36 high-grade endometrial carcinomas Am J Surg Pathol 37 2013 1421 1432
35. S.C. Dowdy Improving oncologic outcomes for women with endometrial cancer: realigning our sights Gynecol Oncol 133 2014 370 374
36. G. Bogani, S.C. Dowdy, W.A. Cliby, F. Ghezzi, D. Rossetti, and A. Mariani Role of pelvic and para-aortic lymphadenectomy in endometrial cancer: current evidence J Obstet Gynaecol Res 40 2014 301 311
37. P. Benedetti Panici, S. Basile, F. Maneschi, and et al. Systematic pelvic lymphadenectomy vs. no lymphadenectomy in early-stage endometrial carcinoma: randomized clinical trial J Natl Cancer Inst 100 2008 1707 1716
38. M.Q. Bernardini, and J.K. Murphy Issues surrounding lymphadenectomy in the management of endometrial cancer Surg Oncol 99 2009 232 241
39. A. Mariani, S.C. Dowdy, W.A. Cliby, and et al. Prospective assessment of lymphatic dissemination in endometrial cancer: a paradigm shift in surgical staging Gynecol Oncol 109 2008 11 18
40. H.S. Chon, R. Abdallah, and J.G. Bosquet Association between endometrial cancer risk classification and gene expression in the cancer genome atlas database Obstet Gynecol 123 Suppl 1 2014 90S
41. M. Morelli, D. Scumaci, A. Di Cello, and et al. DJ-1 in endometrial cancer: a possible biomarker to improve differential diagnosis between subtypes Int J Gynecol Cancer 24 2014 649 658
42. J. Cao, S. Lou, M. Ying, and B. Yang DJ-1 as a human oncogene and potential therapeutic target Biochem Pharmacol 93 2015 241 250
43. M.M. Alhilli, A. Mariani, J.N. Bakkum-Gamez, and et al. Risk-scoring models for individualized prediction of overall survival in low-grade and high-grade endometrial cancer Gynecol Oncol 2014 pii:S0090-8258(14)00809-9
44. S. Bendifallah, G. Canlorbe, E. Arsène, and et al. French Multicenter Study evaluating the risk of lymph node metastases in early-stage endometrial cancer: contribution of a risk scoring system Ann Surg Oncol 22 2015 2722 2728