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Volumn 7, Issue 24, 2015, Pages 2503-2509

Recent advances in vaccination of non-responders to standard dose hepatitis B virus vaccine

Author keywords

Adjuvants; Hepatitis B vaccine; Intradermal vaccine; Non responders; Oral vaccine

Indexed keywords


EID: 84945912754     PISSN: None     EISSN: 19485182     Source Type: Journal    
DOI: 10.4254/wjh.v7.i24.2503     Document Type: Article
Times cited : (89)

References (53)
  • 1
    • 1642337523 scopus 로고    scopus 로고
    • Hepatitis B
    • World Health Organization. Hepatitis B. 2002. Available from: URL: http://apps.who.int/iris/handle/10665/67746
    • (2002)
  • 2
    • 84864336274 scopus 로고    scopus 로고
    • Prevalence of chronic hepatitis B among foreign-born persons living in the United States by country of origin
    • [PMID: 22105832]
    • Kowdley KV, Wang CC, Welch S, Roberts H, Brosgart CL. Prevalence of chronic hepatitis B among foreign-born persons living in the United States by country of origin. Hepatology 2012; 56: 422-433 [PMID: 22105832 DOI: 10.1002/hep.24804]
    • (2012) Hepatology , vol.56 , pp. 422-433
    • Kowdley, K.V.1    Wang, C.C.2    Welch, S.3    Roberts, H.4    Brosgart, C.L.5
  • 3
    • 1642410856 scopus 로고    scopus 로고
    • Available from: URL: http://www.cdc.gov/hepatitis/HBV/HBVfaq.htm#overview 4 Lavanchy D. Hepatitis B virus epidemiology, disease burden, treatment, and current and emerging prevention and control measures
    • [PMID: 14996343]
    • FAQs for Health Professionals: Hepatitis B. Available from: URL: http://www.cdc.gov/hepatitis/HBV/HBVfaq.htm#overview 4 Lavanchy D. Hepatitis B virus epidemiology, disease burden, treatment, and current and emerging prevention and control measures. J Viral Hepat 2004; 11: 97-107 [PMID: 14996343 DOI: 10.1046/j.1365-2893.2003.00487.x]
    • (2004) J Viral Hepat , vol.11 , pp. 97-107
  • 4
    • 0029115078 scopus 로고
    • Global programme for control of hepatitis B infection
    • [PMID: 7571830]
    • Kane M. Global programme for control of hepatitis B infection. Vaccine 1995; 13 Suppl 1: S47-S49 [PMID: 7571830 DOI: 10.1016/0264-410X(95)80050-N]
    • (1995) Vaccine , vol.13 , pp. S47-S49
    • Kane, M.1
  • 5
    • 0020690361 scopus 로고
    • Hepadna viruses: hepatitis B and related viruses
    • [PMID: 6354611]
    • Marion PL, Robinson WS. Hepadna viruses: hepatitis B and related viruses. Curr Top Microbiol Immunol 1983; 105: 99-121 [PMID: 6354611 DOI: 10.1007/9783-642-69159-1_2]
    • (1983) Curr Top Microbiol Immunol , vol.105 , pp. 99-121
    • Marion, P.L.1    Robinson, W.S.2
  • 6
    • 33747875872 scopus 로고    scopus 로고
    • Hepatitis B virus infection: epidemiology and vaccination
    • [PMID: 16754644]
    • Shepard CW, Simard EP, Finelli L, Fiore AE, Bell BP. Hepatitis B virus infection: epidemiology and vaccination. Epidemiol Rev 2006; 28: 112-125 [PMID: 16754644 DOI: 10.1093/epirev/mxj009]
    • (2006) Epidemiol Rev , vol.28 , pp. 112-125
    • Shepard, C.W.1    Simard, E.P.2    Finelli, L.3    Fiore, A.E.4    Bell, B.P.5
  • 7
    • 16544365632 scopus 로고    scopus 로고
    • Clinical practice: prevention of hepatitis B with the hepatitis B vaccine
    • [PMID: 15625334]
    • Poland GA, Jacobson RM. Clinical practice: prevention of hepatitis B with the hepatitis B vaccine. N Engl J Med 2004; 351: 2832-2838 [PMID: 15625334 DOI: 10.1056/NEJMcp041507]
    • (2004) N Engl J Med , vol.351 , pp. 2832-2838
    • Poland, G.A.1    Jacobson, R.M.2
  • 8
    • 0028945294 scopus 로고
    • Risks of chronicity following acute hepatitis B virus infection: a review
    • [PMID: 7795104]
    • Hyams KC. Risks of chronicity following acute hepatitis B virus infection: a review. Clin Infect Dis 1995; 20: 992-1000 [PMID: 7795104 DOI: 10.1093/clinids/20.4.992]
    • (1995) Clin Infect Dis , vol.20 , pp. 992-1000
    • Hyams, K.C.1
  • 9
    • 0029095461 scopus 로고
    • Seroepidemiology of hepatitis B virus in a population of injecting drug users. Association with drug injection patterns
    • [PMID: 7631637]
    • Levine OS, Vlahov D, Koehler J, Cohn S, Spronk AM, Nelson KE. Seroepidemiology of hepatitis B virus in a population of injecting drug users. Association with drug injection patterns. Am J Epidemiol 1995; 142: 331-341 [PMID: 7631637]
    • (1995) Am J Epidemiol , vol.142 , pp. 331-341
    • Levine, O.S.1    Vlahov, D.2    Koehler, J.3    Cohn, S.4    Spronk, A.M.5    Nelson, K.E.6
  • 10
    • 0032978748 scopus 로고    scopus 로고
    • Prevalence of hepatitis B virus infection in the United States: the National Health and Nutrition Examination Surveys, 1976 through 1994
    • [PMID: 9987458]
    • McQuillan GM, Coleman PJ, Kruszon-Moran D, Moyer LA, Lambert SB, Margolis HS. Prevalence of hepatitis B virus infection in the United States: the National Health and Nutrition Examination Surveys, 1976 through 1994. Am J Public Health 1999; 89: 14-18 [PMID: 9987458]
    • (1999) Am J Public Health , vol.89 , pp. 14-18
    • McQuillan, G.M.1    Coleman, P.J.2    Kruszon-Moran, D.3    Moyer, L.A.4    Lambert, S.B.5    Margolis, H.S.6
  • 12
    • 66149171764 scopus 로고    scopus 로고
    • Epidemiology of hepatitis B in the United States
    • [PMID: 19399791]
    • Kim WR. Epidemiology of hepatitis B in the United States. Hepatology 2009; 49: S28-S34 [PMID: 19399791 DOI: 10.1002/hep.22975]
    • (2009) Hepatology , vol.49 , pp. S28-S34
    • Kim, W.R.1
  • 13
    • 33747883642 scopus 로고    scopus 로고
    • Nationwide hepatitis B vaccination program in Taiwan: effectiveness in the 20 years after it was launched
    • [PMID: 16782778]
    • Chien YC, Jan CF, Kuo HS, Chen CJ. Nationwide hepatitis B vaccination program in Taiwan: effectiveness in the 20 years after it was launched. Epidemiol Rev 2006; 28: 126-135 [PMID: 16782778 DOI: 10.1093/epirev/mxj010]
    • (2006) Epidemiol Rev , vol.28 , pp. 126-135
    • Chien, Y.C.1    Jan, C.F.2    Kuo, H.S.3    Chen, C.J.4
  • 14
    • 0032867435 scopus 로고    scopus 로고
    • Contrasting the in situ behavior of a memory B cell clone during primary and secondary immune responses
    • [PMID: 10510371]
    • Vora KA, Tumas-Brundage K, Manser T. Contrasting the in situ behavior of a memory B cell clone during primary and secondary immune responses. J Immunol 1999; 163: 4315-4327 [PMID: 10510371]
    • (1999) J Immunol , vol.163 , pp. 4315-4327
    • Vora, K.A.1    Tumas-Brundage, K.2    Manser, T.3
  • 15
    • 29544432932 scopus 로고    scopus 로고
    • Hepatitis B surface antigen-specific T and B cell memory in individuals who had lost protective antibodies after hepatitis B vaccination
    • [PMID: 16171909]
    • Bauer T, Jilg W. Hepatitis B surface antigen-specific T and B cell memory in individuals who had lost protective antibodies after hepatitis B vaccination. Vaccine 2006; 24: 572-577 [PMID: 16171909 DOI: 10.1016/j.vaccine.2005.08.058]
    • (2006) Vaccine , vol.24 , pp. 572-577
    • Bauer, T.1    Jilg, W.2
  • 17
    • 0036841372 scopus 로고    scopus 로고
    • Immunogenicity of hepatitis B vaccines: implications of immune memory
    • [PMID: 12399197]
    • Koff RS. Immunogenicity of hepatitis B vaccines: implications of immune memory. Vaccine 2002; 20: 3695-3701 [PMID: 12399197 DOI: 10.1016/S0264-410X(02)00405-X]
    • (2002) Vaccine , vol.20 , pp. 3695-3701
    • Koff, R.S.1
  • 19
    • 20144375709 scopus 로고    scopus 로고
    • Molecular analysis of HLA class II associations with hepatitis B virus clearance and vaccine nonresponsiveness
    • [PMID: 15915462]
    • Godkin A, Davenport M, Hill AV. Molecular analysis of HLA class II associations with hepatitis B virus clearance and vaccine nonresponsiveness. Hepatology 2005; 41: 1383-1390 [PMID: 15915462 DOI: 10.1002/hep.20716]
    • (2005) Hepatology , vol.41 , pp. 1383-1390
    • Godkin, A.1    Davenport, M.2    Hill, A.V.3
  • 22
    • 0028345884 scopus 로고
    • Immunogenicity of standard and low dose vaccination using yeast-derived recombinant hepatitis B surface antigen in elderly volunteers
    • [PMID: 8036828]
    • de Rave S, Heijtink RA, Bakker-Bendik M, Boot J, Schalm SW. Immunogenicity of standard and low dose vaccination using yeast-derived recombinant hepatitis B surface antigen in elderly volunteers. Vaccine 1994; 12: 532-534 [PMID: 8036828 DOI: 10.1016/0264410X(94)90313-1]
    • (1994) Vaccine , vol.12 , pp. 532-534
    • de Rave, S.1    Heijtink, R.A.2    Bakker-Bendik, M.3    Boot, J.4    Schalm, S.W.5
  • 23
    • 25444498267 scopus 로고    scopus 로고
    • Undetectable plasma HIV RNA load predicts success after hepatitis B vaccination in HIV-infected persons
    • [PMID: 16142673]
    • Overton ET, Sungkanuparph S, Powderly WG, Seyfried W, Groger RK, Aberg JA. Undetectable plasma HIV RNA load predicts success after hepatitis B vaccination in HIV-infected persons. Clin Infect Dis 2005; 41: 1045-1048 [PMID: 16142673 DOI: 10.1086/433180]
    • (2005) Clin Infect Dis , vol.41 , pp. 1045-1048
    • Overton, E.T.1    Sungkanuparph, S.2    Powderly, W.G.3    Seyfried, W.4    Groger, R.K.5    Aberg, J.A.6
  • 24
    • 57049153416 scopus 로고    scopus 로고
    • Serologic response to hepatitis B vaccine with high dose and increasing number of injections in HIV infected adult patients
    • [PMID: 18984022]
    • Cruciani M, Mengoli C, Serpelloni G, Lanza A, Gomma M, Nardi S, Rimondo C, Bricolo F, Consolaro S, Trevisan M, Bosco O. Serologic response to hepatitis B vaccine with high dose and increasing number of injections in HIV infected adult patients. Vaccine 2009; 27: 17-22 [PMID: 18984022 DOI: 10.1016/j.vaccine.2008.10.040]
    • (2009) Vaccine , vol.27 , pp. 17-22
    • Cruciani, M.1    Mengoli, C.2    Serpelloni, G.3    Lanza, A.4    Gomma, M.5    Nardi, S.6    Rimondo, C.7    Bricolo, F.8    Consolaro, S.9    Trevisan, M.10    Bosco, O.11
  • 25
    • 11144273185 scopus 로고    scopus 로고
    • Hepatitis B vaccine efficacy in patients with chronic liver disease by hepatitis C virus
    • [PMID: 15678203]
    • Mattos AA, Gomes EB, Tovo CV, Alexandre CO, Remião JO. Hepatitis B vaccine efficacy in patients with chronic liver disease by hepatitis C virus. Arq Gastroenterol 2004; 41: 180-184 [PMID: 15678203]
    • (2004) Arq Gastroenterol , vol.41 , pp. 180-184
    • Mattos, A.A.1    Gomes, E.B.2    Tovo, C.V.3    Alexandre, C.O.4    Remião, J.O.5
  • 27
    • 0345690072 scopus 로고    scopus 로고
    • Stage of chronic kidney disease predicts seroconversion after hepatitis B immunization: earlier is better
    • [PMID: 14655190]
    • DaRoza G, Loewen A, Djurdjev O, Love J, Kempston C, Burnett S, Kiaii M, Taylor PA, Levin A. Stage of chronic kidney disease predicts seroconversion after hepatitis B immunization: earlier is better. Am J Kidney Dis 2003; 42: 1184-1192 [PMID: 14655190 DOI: 10.1053/j.ajkd.2003.08.019]
    • (2003) Am J Kidney Dis , vol.42 , pp. 1184-1192
    • DaRoza, G.1    Loewen, A.2    Djurdjev, O.3    Love, J.4    Kempston, C.5    Burnett, S.6    Kiaii, M.7    Taylor, P.A.8    Levin, A.9
  • 28
    • 0033068729 scopus 로고    scopus 로고
    • Comparison of two schedules of hepatitis B vaccination in patients with mild, moderate and severe renal failure
    • [PMID: 10999085]
    • Agarwal SK, Irshad M, Dash SC. Comparison of two schedules of hepatitis B vaccination in patients with mild, moderate and severe renal failure. J Assoc Physicians India 1999; 47: 183-185 [PMID: 10999085]
    • (1999) J Assoc Physicians India , vol.47 , pp. 183-185
    • Agarwal, S.K.1    Irshad, M.2    Dash, S.C.3
  • 31
    • 0036175360 scopus 로고    scopus 로고
    • The effect of high dose and short interval HBV vaccination in individuals with chronic hepatitis C
    • [PMID: 11866284]
    • Idilman R, De MN, Colantoni A, Nadir A, Van Thiel DH. The effect of high dose and short interval HBV vaccination in individuals with chronic hepatitis C. Am J Gastroenterol 2002; 97: 435-439 [PMID: 11866284 DOI: 10.1111/j.15720241.2002.05482.x]
    • (2002) Am J Gastroenterol , vol.97 , pp. 435-439
    • Idilman, R.1    De, M.N.2    Colantoni, A.3    Nadir, A.4    Van Thiel, D.H.5
  • 32
    • 61349183077 scopus 로고    scopus 로고
    • Intradermal hepatitis B vaccination: a systematic review and meta-analysis
    • [PMID: 19200451]
    • Sangaré L, Manhart L, Zehrung D, Wang CC. Intradermal hepatitis B vaccination: a systematic review and meta-analysis. Vaccine 2009; 27: 1777-1786 [PMID: 19200451 DOI: 10.1016/j.vaccine.2009.01.043]
    • (2009) Vaccine , vol.27 , pp. 1777-1786
    • Sangaré, L.1    Manhart, L.2    Zehrung, D.3    Wang, C.C.4
  • 33
    • 0033250953 scopus 로고    scopus 로고
    • Epidermal Langerhans cells: from neurons to nature's adjuvants
    • discussion 259 [PMID: 10643500]
    • Jakob T, Udey MC. Epidermal Langerhans cells: from neurons to nature's adjuvants. Adv Dermatol 1999; 14: 209-258; discussion 259 [PMID: 10643500]
    • (1999) Adv Dermatol , vol.14 , pp. 209-258
    • Jakob, T.1    Udey, M.C.2
  • 35
    • 0033967584 scopus 로고    scopus 로고
    • Cellular and humoral immune responses induced by intradermal or intramuscular vaccination with the major hepatitis B surface antigen
    • [PMID: 10655280]
    • Rahman F, Dahmen A, Herzog-Hauff S, Böcher WO, Galle PR, Löhr HF. Cellular and humoral immune responses induced by intradermal or intramuscular vaccination with the major hepatitis B surface antigen. Hepatology 2000; 31: 521-527 [PMID: 10655280]
    • (2000) Hepatology , vol.31 , pp. 521-527
    • Rahman, F.1    Dahmen, A.2    Herzog-Hauff, S.3    Böcher, W.O.4    Galle, P.R.5    Löhr, H.F.6
  • 36
    • 84856757537 scopus 로고    scopus 로고
    • Efficacy of high-dose intra-dermal hepatitis B virus vaccine in previous vaccination non-responders with chronic liver disease
    • [PMID: 22160636]
    • Dhillon S, Moore C, Li SD, Aziz A, Kakar A, Dosanjh A, Beesla A, Murphy L, Van Thiel DH. Efficacy of high-dose intra-dermal hepatitis B virus vaccine in previous vaccination non-responders with chronic liver disease. Dig Dis Sci 2012; 57: 215-220 [PMID: 22160636 DOI: 10.1007/s10620-011-1996-0]
    • (2012) Dig Dis Sci , vol.57 , pp. 215-220
    • Dhillon, S.1    Moore, C.2    Li, S.D.3    Aziz, A.4    Kakar, A.5    Dosanjh, A.6    Beesla, A.7    Murphy, L.8    Van Thiel, D.H.9
  • 37
    • 67449168123 scopus 로고    scopus 로고
    • Intradermal versus intramuscular hepatitis B vaccination in hemodialysis patients: a prospective open-label randomized controlled trial in nonresponders to primary vaccination
    • [PMID: 19481320]
    • Barraclough KA, Wiggins KJ, Hawley CM, van Eps CL, Mudge DW, Johnson DW, Whitby M, Carpenter S, Playford EG. Intradermal versus intramuscular hepatitis B vaccination in hemodialysis patients: a prospective open-label randomized controlled trial in nonresponders to primary vaccination. Am J Kidney Dis 2009; 54: 95-103 [PMID: 19481320 DOI: 10.1053/j.ajkd.2009.03.010]
    • (2009) Am J Kidney Dis , vol.54 , pp. 95-103
    • Barraclough, K.A.1    Wiggins, K.J.2    Hawley, C.M.3    van Eps, C.L.4    Mudge, D.W.5    Johnson, D.W.6    Whitby, M.7    Carpenter, S.8    Playford, E.G.9
  • 38
    • 0023575837 scopus 로고
    • Intradermal, subcutaneous or intramuscular administration of hepatitis B vaccine: side effects and antibody response
    • [PMID: 3441747]
    • Wahl M, Hermodsson S. Intradermal, subcutaneous or intramuscular administration of hepatitis B vaccine: side effects and antibody response. Scand J Infect Dis 1987; 19: 617-621 [PMID: 3441747]
    • (1987) Scand J Infect Dis , vol.19 , pp. 617-621
    • Wahl, M.1    Hermodsson, S.2
  • 39
    • 0029687236 scopus 로고    scopus 로고
    • Reactogenicity and immunogenicity of a new recombinant hepatitis B vaccine containing Pre S antigens: a preliminary report
    • [PMID: 8736239]
    • Hourvitz A, Mosseri R, Solomon A, Yehezkelli Y, Atsmon J, Danon YL, Koren R, Shouval D. Reactogenicity and immunogenicity of a new recombinant hepatitis B vaccine containing Pre S antigens: a preliminary report. J Viral Hepat 1996; 3: 37-42 [PMID: 8736239 DOI: 10.1111/j.13652893.1996.tb00079.x]
    • (1996) J Viral Hepat , vol.3 , pp. 37-42
    • Hourvitz, A.1    Mosseri, R.2    Solomon, A.3    Yehezkelli, Y.4    Atsmon, J.5    Danon, Y.L.6    Koren, R.7    Shouval, D.8
  • 40
    • 0031029869 scopus 로고    scopus 로고
    • A comparative trial of standard or high-dose S subunit recombinant hepatitis B vaccine versus a vaccine containing S subunit, pre-S1, and pre-S2 particles for revaccination of healthy adult nonresponders
    • [PMID: 9041342]
    • Bertino JS, Tirrell P, Greenberg RN, Keyserling HL, Poland GA, Gump D, Kumar ML, Ramsey K. A comparative trial of standard or high-dose S subunit recombinant hepatitis B vaccine versus a vaccine containing S subunit, pre-S1, and pre-S2 particles for revaccination of healthy adult nonresponders. J Infect Dis 1997; 175: 678-681 [PMID: 9041342 DOI: 10.1093/infdis/175.3.678]
    • (1997) J Infect Dis , vol.175 , pp. 678-681
    • Bertino, J.S.1    Tirrell, P.2    Greenberg, R.N.3    Keyserling, H.L.4    Poland, G.A.5    Gump, D.6    Kumar, M.L.7    Ramsey, K.8
  • 42
    • 0031034072 scopus 로고    scopus 로고
    • Immune response to a new hepatitis B vaccine in healthcare workers who had not responded to standard vaccine: randomised double blind dose-response study
    • [PMID: 9040320]
    • Zuckerman JN, Sabin C, Craig FM, Williams A, Zuckerman AJ. Immune response to a new hepatitis B vaccine in healthcare workers who had not responded to standard vaccine: randomised double blind dose-response study. BMJ 1997; 314: 329-333 [PMID: 9040320 DOI: 10.1136/bmj.314.7077.329]
    • (1997) BMJ , vol.314 , pp. 329-333
    • Zuckerman, J.N.1    Sabin, C.2    Craig, F.M.3    Williams, A.4    Zuckerman, A.J.5
  • 43
    • 0029925874 scopus 로고    scopus 로고
    • Clinical experience with a new recombinant hepatitis-B vaccine in previous non-responders with chronic renal insufficiency
    • [PMID: 8706359]
    • Haubitz M, Ehlerding G, Beigel A, Heuer U, Hemmerling AE, Thoma HA. Clinical experience with a new recombinant hepatitis-B vaccine in previous non-responders with chronic renal insufficiency. Clin Nephrol 1996; 45: 180-182 [PMID: 8706359]
    • (1996) Clin Nephrol , vol.45 , pp. 180-182
    • Haubitz, M.1    Ehlerding, G.2    Beigel, A.3    Heuer, U.4    Hemmerling, A.E.5    Thoma, H.A.6
  • 44
    • 0036841343 scopus 로고    scopus 로고
    • The immunogenicity and reactogenicity profile of a candidate hepatitis B vaccine in an adult vaccine nonresponder population
    • [PMID: 12399191]
    • Jacques P, Moens G, Desombere I, Dewijngaert J, Leroux-Roels G, Wettendorff M, Thoelen S. The immunogenicity and reactogenicity profile of a candidate hepatitis B vaccine in an adult vaccine nonresponder population. Vaccine 2002; 20: 3644-3649 [PMID: 12399191 DOI: 10.1016/S0264-410X(02)00397-3]
    • (2002) Vaccine , vol.20 , pp. 3644-3649
    • Jacques, P.1    Moens, G.2    Desombere, I.3    Dewijngaert, J.4    Leroux-Roels, G.5    Wettendorff, M.6    Thoelen, S.7
  • 45
    • 84875257910 scopus 로고    scopus 로고
    • A novel hepatitis B vaccine containing Advax™, a polysaccharide adjuvant derived from delta inulin, induces robust humoral and cellular immunity with minimal reactogenicity in preclinical testing
    • [PMID: 23306367]
    • Saade F, Honda-Okubo Y, Trec S, Petrovsky N. A novel hepatitis B vaccine containing Advax™, a polysaccharide adjuvant derived from delta inulin, induces robust humoral and cellular immunity with minimal reactogenicity in preclinical testing. Vaccine 2013; 31: 1999-2007 [PMID: 23306367 DOI: 10.1016/j.vaccine.2012.12.077]
    • (2013) Vaccine , vol.31 , pp. 1999-2007
    • Saade, F.1    Honda-Okubo, Y.2    Trec, S.3    Petrovsky, N.4
  • 46
    • 79955088827 scopus 로고    scopus 로고
    • Hepatitis B surface antigen-1018 ISS adjuvant-containing vaccine: a review of HEPLISAV™ safety and efficacy
    • [PMID: 21506639]
    • Cooper C, Mackie D. Hepatitis B surface antigen-1018 ISS adjuvant-containing vaccine: a review of HEPLISAV™ safety and efficacy. Expert Rev Vaccines 2011; 10: 417-427 [PMID: 21506639 DOI: 10.1586/erv.10.162]
    • (2011) Expert Rev Vaccines , vol.10 , pp. 417-427
    • Cooper, C.1    Mackie, D.2
  • 47
    • 84865283534 scopus 로고    scopus 로고
    • Strong and multi-antigen specific immunity by hepatitis B core antigen (HBcAg)-based vaccines in a murine model of chronic hepatitis B: HBcAg is a candidate for a therapeutic vaccine against hepatitis B virus
    • [PMID: 22884884]
    • Akbar SM, Chen S, Al-Mahtab M, Abe M, Hiasa Y, Onji M. Strong and multi-antigen specific immunity by hepatitis B core antigen (HBcAg)-based vaccines in a murine model of chronic hepatitis B: HBcAg is a candidate for a therapeutic vaccine against hepatitis B virus. Antiviral Res 2012; 96: 59-64 [PMID: 22884884 DOI: 10.1016/j.antiviral.2012.07.011]
    • (2012) Antiviral Res , vol.96 , pp. 59-64
    • Akbar, S.M.1    Chen, S.2    Al-Mahtab, M.3    Abe, M.4    Hiasa, Y.5    Onji, M.6
  • 48
    • 84912010867 scopus 로고    scopus 로고
    • In vitro stimulation with HBV therapeutic vaccine candidate Nasvac activates B and T cells from chronic hepatitis B patients and healthy donors
    • [PMID: 25193323]
    • Lobaina Y, Hardtke S, Wedemeyer H, Aguilar JC, Schlaphoff V. In vitro stimulation with HBV therapeutic vaccine candidate Nasvac activates B and T cells from chronic hepatitis B patients and healthy donors. Mol Immunol 2015; 63: 320-327 [PMID: 25193323 DOI: 10.1016/j.molimm.2014.08.003]
    • (2015) Mol Immunol , vol.63 , pp. 320-327
    • Lobaina, Y.1    Hardtke, S.2    Wedemeyer, H.3    Aguilar, J.C.4    Schlaphoff, V.5
  • 50
    • 37049026517 scopus 로고    scopus 로고
    • Open label trial of therapeutic hepatitis B vaccine V-5 Immunitor (V5) delivered by oral route
    • Batdelger D, Dandii D, Jirathitikal V, Bourinbaia AS. Open label trial of therapeutic hepatitis B vaccine V-5 Immunitor (V5) delivered by oral route. Lett Drug Des Discov 2007; 4: 540-544 [DOI: 10.2174/157018007782794545]
    • (2007) Lett Drug Des Discov , vol.4 , pp. 540-544
    • Batdelger, D.1    Dandii, D.2    Jirathitikal, V.3    Bourinbaia, A.S.4
  • 51
    • 84873088935 scopus 로고    scopus 로고
    • A novel therapeutic hepatitis B vaccine induces cellular and humoral immune responses and breaks tolerance in hepatitis B virus (HBV) transgenic mice
    • [PMID: 23306359]
    • Buchmann P, Dembek C, Kuklick L, Jäger C, Tedjokusumo R, von Freyend MJ, Drebber U, Janowicz Z, Melber K, Protzer U. A novel therapeutic hepatitis B vaccine induces cellular and humoral immune responses and breaks tolerance in hepatitis B virus (HBV) transgenic mice. Vaccine 2013; 31: 1197-1203 [PMID: 23306359 DOI: 10.1016/j.vaccine.2012.12.074]
    • (2013) Vaccine , vol.31 , pp. 1197-1203
    • Buchmann, P.1    Dembek, C.2    Kuklick, L.3    Jäger, C.4    Tedjokusumo, R.5    von Freyend, M.J.6    Drebber, U.7    Janowicz, Z.8    Melber, K.9    Protzer, U.10
  • 52
    • 48749095598 scopus 로고    scopus 로고
    • Excellent response rate to a double dose of the combined hepatitis A and B vaccine in previous nonresponders to hepatitis B vaccine
    • [PMID: 18544037]
    • Cardell K, Akerlind B, Sällberg M, Frydén A. Excellent response rate to a double dose of the combined hepatitis A and B vaccine in previous nonresponders to hepatitis B vaccine. J Infect Dis 2008; 198: 299-304 [PMID: 18544037 DOI: 10.1086/589722]
    • (2008) J Infect Dis , vol.198 , pp. 299-304
    • Cardell, K.1    Akerlind, B.2    Sällberg, M.3    Frydén, A.4
  • 53
    • 80052501750 scopus 로고    scopus 로고
    • Randomized trial of the immunogenicity and safety of the Hepatitis B vaccine given in an accelerated schedule coadministered with the human papillomavirus type 16/18 AS04-adjuvanted cervical cancer vaccine
    • [PMID: 21734063]
    • Leroux-Roels G, Haelterman E, Maes C, Levy J, De Boever F, Licini L, David MP, Dobbelaere K, Descamps D. Randomized trial of the immunogenicity and safety of the Hepatitis B vaccine given in an accelerated schedule coadministered with the human papillomavirus type 16/18 AS04-adjuvanted cervical cancer vaccine. Clin Vaccine Immunol 2011; 18: 1510-1518 [PMID: 21734063]
    • (2011) Clin Vaccine Immunol , vol.18 , pp. 1510-1518
    • Leroux-Roels, G.1    Haelterman, E.2    Maes, C.3    Levy, J.4    De Boever, F.5    Licini, L.6    David, M.P.7    Dobbelaere, K.8    Descamps, D.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.