-
1
-
-
33748083041
-
Long-term clinical improvement in MPTP-lesioned primates after gene therapy with AAV-hAADC
-
Bankiewicz KS, Forsayeth J, Eberling JL, Sanchez-Pernaute R, Pivirotto P, Bringas J, Herscovitch P, Carson RE, Eckelman W, Reutter B, Cunningham J (2006) Long-term clinical improvement in MPTP-lesioned primates after gene therapy with AAV-hAADC. Mol Ther 14:564-570.
-
(2006)
Mol Ther
, vol.14
, pp. 564-570
-
-
Bankiewicz, K.S.1
Forsayeth, J.2
Eberling, J.L.3
Sanchez-Pernaute, R.4
Pivirotto, P.5
Bringas, J.6
Herscovitch, P.7
Carson, R.E.8
Eckelman, W.9
Reutter, B.10
Cunningham, J.11
-
2
-
-
84895442417
-
Parkinson’s disease gene therapy: Success by design meets failure by efficacy
-
Bartus RT, Weinbert MS, Samulski RJ (2014) Parkinson’s disease gene therapy: Success by design meets failure by efficacy. Mol Ther 22:487-497.
-
(2014)
Mol Ther
, vol.22
, pp. 487-497
-
-
Bartus, R.T.1
Weinbert, M.S.2
Samulski, R.J.3
-
3
-
-
84868156476
-
Advancing neurotrophic factors as treatments for age-related neurodegenerative diseases: Developing and demonstrating “clinical proof-of-concept” for AAV-neurturin (CERE-120) in Parkinson’s disease
-
Bartus RT, Baumann TL, Brown L, Kruegel BR, Ostrove JM, Herzog CD (2013) Advancing neurotrophic factors as treatments for age-related neurodegenerative diseases: developing and demonstrating “clinical proof-of-concept” for AAV-neurturin (CERE-120) in Parkinson’s disease. Neurobiol Aging 34:35-61.
-
(2013)
Neurobiol Aging
, vol.34
, pp. 35-61
-
-
Bartus, R.T.1
Baumann, T.L.2
Brown, L.3
Kruegel, B.R.4
Ostrove, J.M.5
Herzog, C.D.6
-
4
-
-
79951476995
-
Bioactivity of AAV2-NeurturinNRTN gene therapy (CERE-120) in Parkinson’s disease: A comparison of post-mortem and nonhuman primate brain tissue
-
Bartus RT, Herzog CD, Chu Y, Wilson A, Brown L, Johnson E, Olanow CW, Mufson EJ, Kordower JH (2011) Bioactivity of AAV2-NeurturinNRTN gene therapy (CERE-120) in Parkinson’s disease: A comparison of post-mortem and nonhuman primate brain tissue. Mov Disord 26:27-36.
-
(2011)
Mov Disord
, vol.26
, pp. 27-36
-
-
Bartus, R.T.1
Herzog, C.D.2
Chu, Y.3
Wilson, A.4
Brown, L.5
Johnson, E.6
Olanow, C.W.7
Mufson, E.J.8
Kordower, J.H.9
-
5
-
-
84927921640
-
Post-mortem assessment of the short and long-term effects of the trophic factor neurturin in patients with α-synucleinopathies
-
Bartus RT, Kordower JH, Johnson EM Jr, Brown L, Kruegel BR, Chu Y, Baumann TL, Lang AE, Olanow CW, Herzog CD (2015) Post-mortem assessment of the short and long-term effects of the trophic factor neurturin in patients with α-synucleinopathies. Neurobiol Dis 78:162-171.
-
(2015)
Neurobiol Dis
, vol.78
, pp. 162-171
-
-
Bartus, R.T.1
Kordower, J.H.2
Johnson, E.M.3
Brown, L.4
Kruegel, B.R.5
Chu, Y.6
Baumann, T.L.7
Lang, A.E.8
Olanow, C.W.9
Herzog, C.D.10
-
6
-
-
84880932230
-
Disease duration and the integrity of the nigrostriatal system in Parkinson’s disease
-
Kordower JH, Olanow CW, Dodiya HB, Chu Y, Beach TG, Adler CH, Halliday GM, Bartus RT (2013) Disease duration and the integrity of the nigrostriatal system in Parkinson’s disease. Brain 136:2419-2431.
-
(2013)
Brain
, vol.136
, pp. 2419-2431
-
-
Kordower, J.H.1
Olanow, C.W.2
Dodiya, H.B.3
Chu, Y.4
Beach, T.G.5
Adler, C.H.6
Halliday, G.M.7
Bartus, R.T.8
-
7
-
-
78349247631
-
Gene delivery of AAV2-neurturin for Parkinson’s disease: A double-blind, randomised, controlled trial
-
Marks WJ Jr, Bartus RT, Siffert J, Davis CS, Lozano A, Boulis N, Vitek J, Stacy M, Turner D, Verhagen L, Bakay R, Watts R, Guthrie B, Jankovic J, Simpson R, Tagliati M, Alterman R, Stern M, Baltuch G, Starr PA, et al. (2010) Gene delivery of AAV2-neurturin for Parkinson’s disease: a double-blind, randomised, controlled trial. Lancet Neurol 9:1164-1172.
-
(2010)
Lancet Neurol
, vol.9
, pp. 1164-1172
-
-
Marks, W.J.1
Bartus, R.T.2
Siffert, J.3
Davis, C.S.4
Lozano, A.5
Boulis, N.6
Vitek, J.7
Stacy, M.8
Turner, D.9
Verhagen, L.10
Bakay, R.11
Watts, R.12
Guthrie, B.13
Jankovic, J.14
Simpson, R.15
Tagliati, M.16
Alterman, R.17
Stern, M.18
Baltuch, G.19
Starr, P.A.20
more..
-
8
-
-
84860130544
-
Long-term evaluation of a phase 1 study of AADC gene therapy for Parkinson’s disease
-
Mittermeyer G, Christine CW, Rosenbluth KH, Baker SL, Starr P, Larson P, Kaplan PL, Forsayeth J, Aminoff MJ, Bankiewicz KS (2012) Long-term evaluation of a phase 1 study of AADC gene therapy for Parkinson’s disease. Hum Gene Ther 23:377-381.
-
(2012)
Hum Gene Ther
, vol.23
, pp. 377-381
-
-
Mittermeyer, G.1
Christine, C.W.2
Rosenbluth, K.H.3
Baker, S.L.4
Starr, P.5
Larson, P.6
Kaplan, P.L.7
Forsayeth, J.8
Aminoff, M.J.9
Bankiewicz, K.S.10
-
9
-
-
84937734362
-
Gene delivery of neurturin to putamen and substania nigra in Parkinson disease: A double-blind, randomized controlled trial
-
Warren Olanow C, Bartus RT, Baumann TL, Factor S, Boulis N, Stacy M, Turner DA, Marks W, Larson P, Starr PA, Jankovic J, Simpson R, Watts R, Guthrie B, Poston K, Henderson JM, Stern M, Baltuch G, Goetz CG, Herzog C, et al. (2015) Gene delivery of neurturin to putamen and substania nigra in Parkinson disease: A double-blind, randomized controlled trial. Ann Neurol 78:248-257.
-
(2015)
Ann Neurol
, vol.78
, pp. 248-257
-
-
Warren Olanow, C.1
Bartus, R.T.2
Baumann, T.L.3
Factor, S.4
Boulis, N.5
Stacy, M.6
Turner, D.A.7
Marks, W.8
Larson, P.9
Starr, P.A.10
Jankovic, J.11
Simpson, R.12
Watts, R.13
Guthrie, B.14
Poston, K.15
Henderson, J.M.16
Stern, M.17
Baltuch, G.18
Goetz, C.G.19
Herzog, C.20
more..
|