Epigenetics: Place your BETs

Nature Reviews Cancer

Volumn 15, Issue 11, 2015, Pages 638-

  Seton Rogers, Sarah ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

BETA CATENIN; BROMODOMAIN INHIBITOR; HYBRID PROTEIN; K RAS PROTEIN; POLYCOMB REPRESSIVE COMPLEX 2; SHORT HAIRPIN RNA; WNT PROTEIN;

ACUTE MYELOBLASTIC LEUKEMIA; APOPTOSIS; CHROMATIN; ENHANCER REGION; EPIGENETICS; HUMAN; IN VITRO STUDY; LEUKEMIA; LEUKEMIA CELL LINE; NONHUMAN; NOTE; PANCREAS ADENOCARCINOMA; PRIORITY JOURNAL; STEM CELL; THERAPY EFFECT;

EID: 84945456244     PISSN: 1474175X     EISSN: 14741768     Source Type: Journal    
DOI: 10.1038/nrc4035     Document Type: Note

References (3)

1. Fong, C. Y. et al. BET inhibitor resistance emerges from leukaemia stem cells. Nature 525, 538-542 (2015)
2. Rathert, P., Roth, M. et al. Transcriptional plasticity promotes primary and acquired resistance to BET inhibition. Nature 525, 543-547 (2015)
3. Mazur, P. K., Herner, A. et al. Combined inhibition of BET family proteins and histone deacetylases as a potential epigenetics-based therapy for pancreatic ductal adenocarcinoma. Nat. Med. 21, 1163-1171 (2015)