Potent Antibacterial Activity of Copper Embedded into Silicone and Polyurethane

ACS Applied Materials and Interfaces

Volumn 7, Issue 41, 2015, Pages 22807-22813

  Sehmi, Sandeep K ^a,b,c   Noimark, Sacha ^a   Weiner, Jonathan ^d   Allan, Elaine ^c   MacRobert, Alexander J ^b   Parkin, Ivan P ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c UNIVERSITY COLLEGE LONDON   (United Kingdom)

^d IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

antimicrobial; bacteria; copper; hospital acquired infections; nanoparticle; polymers

Indexed keywords

BACTERIA; COPPER; ESCHERICHIA COLI; FUNCTIONAL POLYMERS; HOSPITALS; MICROORGANISMS; NANOPARTICLES; POLYURETHANES; SILICONES;

ANTI-BACTERIAL ACTIVITY; ANTI-MICROBIAL ACTIVITY; ANTIMICROBIAL; ANTIMICROBIAL MATERIALS; HOSPITAL ACQUIRED INFECTION; MEDICAL GRADE POLYMERS; METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS; MICROBIAL CONTAMINATION;

POLYMERS;

ANTIINFECTIVE AGENT; COPPER; METAL NANOPARTICLE; POLYURETHAN; SILICONE DERIVATIVE; WATER;

DRUG EFFECTS; ESCHERICHIA COLI; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MICROBIAL SENSITIVITY TEST; MICROBIAL VIABILITY; PARTICLE SIZE; ULTRASTRUCTURE; X RAY PHOTOELECTRON SPECTROSCOPY;

ANTI-BACTERIAL AGENTS; COPPER; ESCHERICHIA COLI; METAL NANOPARTICLES; METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS; MICROBIAL SENSITIVITY TESTS; MICROBIAL VIABILITY; PARTICLE SIZE; PHOTOELECTRON SPECTROSCOPY; POLYURETHANES; SILICONES; WATER;

EID: 84945313967     PISSN: 19448244     EISSN: 19448252     Source Type: Journal    
DOI: 10.1021/acsami.5b08665     Document Type: Article

References (31)

1. Agency for Healthcare Research and Quality (AHRQ). AHRQ's efforts to prevent and reduce healthcare-associated infections, (2009).
2. Klevens, R. M.; Edwards, J. R.; Richards, C. L.; Horan, T. C.; Gaynes, R. P.; Pollock, D. A.; Cardo, D. M. Estimating Healthcare-associated Infections and Deaths in U.S. Hospitals Public Health Rep. 2007) 2, 160-166
3. World Health Organization. The Burden of Health Care-Associated Infection Worldwide. http://www.who.int/gpsc/country-work/burden-hcai/en/, 2010.
4. Hospital Hygiene: Hospital infection rates in developed countries, 2010. http://hospitalhygiene.info.
5. Sandle, T.; Babenko, D.; Lavrinenko, A.; Azizov, I.; Chesca, A. Comparative Evaluation of Traditional Susceptibility Testing for MRSA with the PCR Approach Adv. Microbiol. 2014, 19, 153-164 10.4236/aim.2014.416130
6. Syndor, E. R.; Perl, T. M. Hospital Epidemiology and Infection Control in Acute-Care Settings Clin. Microbiol. Rev. 2011, 24, 141-173 10.1128/CMR.00027-10
7. Kleinpell, R. M.; Munro, C. L.; Giuliano, K. K. Targeting Health Care-Associated Infections: Evidence-Based Strategies, In Patient Safety and Quality: An Evidence-Based Handbook for Nurses; Hughes, R. G., Ed. Agency for Healthcare Research and Quality: Rockville, MD, 2008, Chapter 42.
8. Noimark, S.; Dunnill, C. W.; Wilson, M.; Parkin, I. P. The Role of Surfaces in Catheter-Associated Infections Adv. Drug Delivery Rev. 2009, 65, 570-580
9. Noimark, S.; Dunnill, C. W.; Kay, M.; Perni, S.; Prokopovich, P.; Ismail, S.; Wilson, M.; Parkin, I. P. Incorporation of Methylene Blue and Nanogold into Polyvinyl Chloride Catheters; A New Approach for Light-Activated Disinfection of Surfaces J. Mater. Chem. 2012, 22, 15388-15396 10.1039/c2jm31987j
10. Page, K.; Wilson, M.; Mordan, N. J.; Chrzanowski, W.; Knowles, J.; Parkin, I. P. The Use of Zinc Oxide Nanoparticles to Enhance the Antibacterial Properties of Light-Activated Polydimethylsiloxane Containing Crystal Violet J. Mater. Sci. 2011, 46, 6355-6363 10.1007/s10853-011-5582-9
11. Ozkan, E.; Allan, E.; Parkin, I. P. The Antibacterial Properties of Light-Activated Polydimethylsiloxane Containing Crystal Violet RSC Adv. 2014, 4, 51711-51715 10.1039/C4RA08503E
12. Perni, S.; Piccirillo, C.; Kafizas, A.; Uppal, M.; Pratten, J.; Wilson, M.; Parkin, I. P. Antibacterial Activity of Light-Activated Silicone Containing Methylene Blue and Gold Nanoparticles of Different Sizes J. Cluster Sci. 2010, 21, 427-438 10.1007/s10876-010-0319-5
13. Noimark, S.; Dunnill, C. W.; Kay, M.; Perni, S.; Prokopovich, P.; Ismail, S.; Wilson, M.; Parkin, I. P. Incorporation of Methylene Blue and Nanogold into Polyvinyl Chloride Catheters; A New Approach for Light-Activated Disinfection of Surfaces J. Mater. Chem. 2012, 22, 15388-15396 10.1039/c2jm31987j
14. Noimark, S.; Bovis, M.; MacRobert, A. J.; Correia, A.; Allan, E.; Wilson, M.; Parkin, I. P. Photobactericidal Polymers; The Incorporation of Crystal Violet and Nanogold into Medical Grade Silicone RSC Adv. 2013, 3, 18383-18394 10.1039/c3ra42629g
15. Noimark, S.; Allan, E.; Parkin, I. P. Light-Activated Antimicrobial Surfaces with Enhanced Efficacy Induced by a Dark-Activated Mechanism Chem. Sci. 2014, 5, 2216-2223 10.1039/c3sc53186d
16. Noimark, S.; Weiner, J.; Noor, N.; Allan, E.; Williams, C. K.; Shaffer, M. S.; Parkin, I. P. Dual-Mechanism Antimicrobial Polymer-ZnO Nanoparticle and Crystal Violet-Encapsulated Silicone Adv. Funct. Mater. 2015, 25, 1367-1373 10.1002/adfm.201402980
17. Sehmi, S. K.; Noimark, S.; Bear, J. C.; Peveler, W. J.; Bovis, M.; Allan, E.; MacRobert, A. J.; Parkin, I. P. Lethal Photosensitisation of Staphylococcus Aureus and Escherichia Coli using Crystal Violet and Zinc Oxide-Encapsulated Polyurethane J. Mater. Chem. B 2015, 3, 6490-6500 10.1039/C5TB00971E
18. Treter, J.; Macedo, A. J. Catheters: A Suitable Surface for Biofilm Formation. Science against Microbial Pathogens: Communicating Current Research and Technological Advances; Formatex Research Center: Badajoz, Spain, 2011. pp 835-842.
19. Ramyadevi, J.; Jeyasubramanian, K.; Marikani, A.; Rajakumar, G.; Rahuman, A. A. Synthesis and Antimicrobial Activity of Copper Nanoparticles Mater. Lett. 2012, 71, 114-116 10.1016/j.matlet.2011.12.055
20. Ruparelia, J. P.; Chatterjee, A. K.; Duttagupta, S. P.; Mukherji, S. Strain Specificity in Antimicrobial Activity of Silver and Copper Nanoparticles Acta Biomater. 2008, 4, 707-716 10.1016/j.actbio.2007.11.006
21. Rai, R. V.; Bai, J. A. Nanoparticles and their Potential Application as Antimicrobials, Communicating Current Research and Technological Advances; Microbiology Book Series, No. 3. Formatex Research Center: Badajoz, Spain, 2011, pp 197-209.
22. Esteban-Cubillo, A.; Pecharroman, C.; Aguilar, E.; Santaren, J.; Moya, J. S. Antibacterial Activity of Copper Monodispersed Nanoparticles into Sepiolite J. Mater. Sci. 2006, 41, 5208-5212 10.1007/s10853-006-0432-x
23. 4 Alloy J. Achievements Mater. Manufacturing Eng. 2010, 42, 9-25
24. Manzl, C.; Enrich, J.; Ebner, H.; Dallinger, R.; Krumschnabel, G. Copper-Induced Formation of Reactive Oxygen Species Causes Cell Death and Disruption of Calcium Homeostasis in Trout Hepatocytes Toxicology 2004, 196, 57-64 10.1016/j.tox.2003.11.001
25. Vadlapudi, V.; Kaladhar, D.S.V.G.K.; Behara, M.; Sujatha, B.; Kishore Naidu, G. Synthesis of Green Metallic Nanoparticles (NPs) and Applications Orient. J. Chem. 2013, 29, 1589-1595 10.13005/ojc/290442
26. Xiong, J.; Wang, Y.; Xue, Q.; Wu, X. Synthesis of Highly Stable Dispersions of Nanosized Copper Particles using L-Ascorbic Acid Green Chem. 2011, 13, 900-904 10.1039/c0gc00772b
27. Crick, C. R.; Noimark, S.; Peveler, W. J.; Bear, J. C.; Ivanov, P.; Edel, J. B.; Parkin, I. P. Advanced Analysis of Nanoparticle Composites-A Means Towards Increasing the Efficiency of Functional Materials RSC Adv. 2015, 5, 53789-53795 10.1039/C5RA08788K
28. Nikaido, H. Multidrug Resistance in Bacteria Annu. Rev. Biochem. 2009, 78, 119-149 10.1146/annurev.biochem.78.082907.145923
29. Shi, M.; Kwon, H. S.; Peng, Z.; Elder, A.; Yang, H. Effects of Surface Chemistry on the Generation of Reactive Oxygen Species by Copper Nanoparticles ACS Nano 2012, 6, 2157-2164 10.1021/nn300445d
30. Grass, G.; Rensing, C.; Solioz, M. Metallic Copper as an Antimicrobial Surface Appl. Environ. Microbiol. 2011, 77, 1541-1547 10.1128/AEM.02766-10
31. Yaghini, E.; Pirker, K. F.; Kay, C. W. M.; Seifalian, A. M.; MacRobert, A. J. Quantification of Reactive Oxygen Species Generation by Photoexcitation of PEGylated Quantum Dots Small 2014, 24, 5106-5115 10.1002/smll.201401209