Vitamin D fortification and seasonality of birth in type 1 diabetic cases: D-tect study

Journal of Developmental Origins of Health and Disease

Volumn 7, Issue 1, 2016, Pages 114-119

  Jacobsen, R ^a,g   Moldovan, M ^b   Vaag, A A ^c,d   Hypponen, E ^b   Heitmann, B L ^a,e,f,g  

^a FREDERIKSBERG HOSPITAL   (Denmark)

^b UNIVERSITY OF SOUTH AUSTRALIA   (Australia)

^c Rigshospitalet   (Denmark)

^d UNIVERSITY OF COPENHAGEN   (Denmark)

^e UNIVERSITY OF SYDNEY   (Australia)

^f UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

^g The Capital Region   (Denmark)

Author keywords

fortification; seasonality of birth; type 1 diabetes; Vitamin D

Indexed keywords

MARGARINE; VITAMIN D;

ADOLESCENT; CHILD; COHORT ANALYSIS; COMPLICATION; DENMARK; DIABETES MELLITUS, TYPE 1; FEMALE; FORTIFIED FOOD; HUMAN; MALE; SEASON; VITAMIN D DEFICIENCY;

ADOLESCENT; CHILD; COHORT STUDIES; DENMARK; DIABETES MELLITUS, TYPE 1; FEMALE; FOOD, FORTIFIED; HUMANS; MALE; MARGARINE; SEASONS; VITAMIN D; VITAMIN D DEFICIENCY;

EID: 84945262620     PISSN: 20401744     EISSN: 20401752     Source Type: Journal    
DOI: 10.1017/S2040174415007849     Document Type: Article

References (25)

1. Atkinson MA, Eisenbarth GS, Michels AW. Type 1 diabetes. Lancet. 2014; 383, 69-82.
2. Hypponen E. Preventing vitamin D deficiency in pregnancy: importance for the mother and child. An Nutr Metab. 2011; 59, 28-31.
3. McGrath J. Does 'imprinting' with low prenatal vitamin D contribute to the risk of various adult disorders? Med Hypotheses. 2001; 56, 367-371.
4. Dong JY, Zhang WG, Chen JJ, et al. Vitamin D intake and risk of type 1 diabetes: a meta-analysis of observational studies. Nutrients. 2013; 5, 3551-3562.
5. Rothwell PM, Staines A, Smail P, Wadsworth E, McKinney P. Seasonality of birth of patients with childhood diabetes in Britain. BMJ. 1996; 312, 1456-1457.
6. Laron Z. Interplay between heredity and environment in the recent explosion of type 1 childhood diabetes mellitus. Am J Med Genet. 2002; 115, 4-7.
7. Lips P. Vitamin D physiology. Prog Biophys Mol Biol. 2006; 92, 4-8.
8. Kimlin MG. Geographic location and vitamin D synthesis. Mol Aspects Med. 2008; 29, 453-461.
9. Madsen KH, Rasmussen LB, Andersen R, et al. Randomized controlled trial of the effects of vitamin D-fortified milk and bread on serum 25-hydroxyvitamin D concentrations in families in Denmark during winter: the VitmaD study. Am J Clin Nutr. 2013; 98, 374-382.
10. Jacobsen R, Hypponen E, Sorensen TI, Vaag AA, Heitmann BL. Gestational and early infancy exposure to margarine fortified with vitamin D through a national Danish programme and the risk of type 1 diabetes: the D-tect study. Plos One. 2015; 10, e0128631.
11. Haradsdóttir J, Thaarup S. Tilsætning af vitaminer og mineraler til levnedsmidler (The Fortification of Foods with Vitamins and Minerals) 1989. Nordic Council of Ministers: Copenhagen.
12. Pedersen CB. The Danish Civil Registration System. Scand J Public Health. 2011; 39, 22-25.
13. Svensson J, Lyngaae-Jorgensen A, Carstensen B, Simonsen LB, Mortensen HB. Long-term trends in the incidence of type 1 diabetes in Denmark: the seasonal variation changes over time. Pediatr Diabetes. 2009; 10, 248-254.
14. McKinney PA. Seasonality of birth in patients with childhood type I diabetes in 19 European regions. Diabetologia. 2001; 44 (Suppl. 3), B67-B74.
15. Streym S, Rejnmark L, Mosekilde L, Vestergaard P. No effect of season of birth on risk of type 1 diabetes, cancer, schizophrenia and ischemic heart disease, while some variations may be seen for pneumonia and multiple sclerosis. Dermatoendocrinol. 2013; 5, 309-316.
16. Dror DK, Allen LH. Vitamin D inadequacy in pregnancy: biology, outcomes, and interventions. Nutr Rev. 2010; 68, 465-477.
17. Hypponen E, Power C. Hypovitaminosis D in British adults at age 45 y: nationwide cohort study of dietary and lifestyle predictors. Am J Clin Nutr. 2007; 85, 860-868.
18. McGrath JJ, Eyles DW, Pedersen CB, et al. Neonatal vitamin D status and risk of schizophrenia: a population-based case-control study. Arch Gen Psychiatry. 2010; 67, 889-894.
19. Jongbloet PH, Groenewoud HM, Hirasing RA, Van BS. Seasonality of birth in patients with childhood diabetes in the Netherlands. Diabetes Care. 1998; 21, 190-191.
20. Jongbloet PH. Over-ripeness ovopathy: a challenging hypothesis for sex ratio modulation. Hum Reprod. 2004; 19, 769-774.
21. Bach JF, Chatenoud L. The hygiene hypothesis: an explanation for the increased frequency of insulin-dependent diabetes. Cold Spring Harb Perspect Med. 2012; 2, a007799.
22. Stene LC, Rewers M. Immunology in the clinic review series; focus on type 1 diabetes and viruses: the enterovirus link to type 1 diabetes: critical review of human studies. Clin Exp Immunol. 2012; 168, 12-23.
23. Svensson J, Carstensen B, Mortensen HB, Borch-Johnsen K. Early childhood risk factors associated with type 1 diabetes-is gender important? Eur J Epidemiol. 2005; 20, 429-434.
24. Parekh D, Lax S, Dancer R, Perkins G, Thickett D. Vitamin D deficiency and bacterial load in a murin model of sepsis-induced lung injury. The Lancet. 2014; 383, S15.
25. Fagt S, Trolle E. Forsyningen af fødevarer 1955-1999. Udviklingen i danskernes kost-forbrug, indkøb og vaner (The Supply of Food from 1955 to 1999. Overview of theDevelopments in theDanishDiet-Consumption, Purchasing and Habits), 2001. Fødevaredirektoratet: Søborg.