PIRO concept: Staging of sepsis

Journal of Postgraduate Medicine

Volumn 61, Issue 4, 2015, Pages 235-242

  Rathour, S ^a   Kumar, S ^a   Hadda, V ^b   Bhalla, A ^a   Sharma, N ^a   Varma, S ^a  

^a POSTGRADUATE INSTITUTE OF MEDICAL EDUCATION AND RESEARCH   (India)

^b ALL INDIA INSTITUTE OF MEDICAL SCIENCES   (India)

Author keywords

Emergency services; infection; organ dysfunction; predisposition; response; sepsis

Indexed keywords

ADULT; AGE; ARTERIAL BLOOD; ARTERIAL OXYGEN TENSION; ARTICLE; CHRONIC LIVER DISEASE; CHRONIC OBSTRUCTIVE LUNG DISEASE; COMORBIDITY; CREATININE BLOOD LEVEL; DIAGNOSTIC TEST ACCURACY STUDY; DIASTOLIC BLOOD PRESSURE; DISEASE CLASSIFICATION; DISEASE PREDISPOSITION; EMERGENCY HEALTH SERVICE; ENCEPHALITIS; FEMALE; GLASGOW COMA SCALE; HUMAN; MAJOR CLINICAL STUDY; MALE; MEAN ARTERIAL PRESSURE; MENINGITIS; MIDDLE AGED; MORTALITY; NEOPLASM; OBSERVATIONAL STUDY; PARTIAL THROMBOPLASTIN TIME; PNEUMONIA; PREDICTIVE VALUE; PREDISPOSITION INFECTION RESPONSE AND ORGAN DYSFUNCTION STAGING; PROSPECTIVE STUDY; PROTHROMBIN TIME; RECEIVER OPERATING CHARACTERISTIC; RESPONSE VARIABLE; SEPSIS; SYSTOLIC BLOOD PRESSURE; TACHYPNEA; TERTIARY CARE CENTER; URINARY TRACT INFECTION; URINE VOLUME; AGED; INDIA; MULTIVARIATE ANALYSIS; ORGAN DYSFUNCTION SCORE; PROGNOSIS; SENSITIVITY AND SPECIFICITY; SEVERITY OF ILLNESS INDEX; STATISTICAL MODEL; VERY ELDERLY;

ADULT; AGED; AGED, 80 AND OVER; EMERGENCY SERVICE, HOSPITAL; FEMALE; GLASGOW COMA SCALE; HOSPITAL MORTALITY; HUMANS; INDIA; LOGISTIC MODELS; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; ORGAN DYSFUNCTION SCORES; PROGNOSIS; PROSPECTIVE STUDIES; SENSITIVITY AND SPECIFICITY; SEPSIS; SEVERITY OF ILLNESS INDEX;

EID: 84945177431     PISSN: 00223859     EISSN: 09722823     Source Type: Journal    
DOI: 10.4103/0022-3859.166511     Document Type: Article

References (19)

1. Lagu T, Rothberg MB, Shieh MS, Pekow PS, Steingrub JS, Lindenauer PK. Hospitalizations, costs, and outcomes of severe sepsis in the United States 2003 to 2007. Crit Care Med 2012;40:754-61.
2. Kumar G, Kumar N, Taneja A, Kaleekal T, Tarima S, McGinley E, et al. Milwaukee Initiative in Critical Care Outcomes Research Group of Investigators. Nationwide trends of severe sepsis in the 21st century (2000-2007). Chest 2011;140:1223-31.
3. Bone RC, Balk RA, Cerra FB, Dellinger RP, Fein AM, Knaus WA, et al. Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. The ACCP/SCCM Consensus Conference Committee. American College of Chest Physicians/ Society of Critical Care Medicine. Chest 1992;101:1644-55.
4. Poeze M, Ramsay G, Gerlach H, Rubulotta F, Levy M. An international sepsis survey: A study of doctors' knowledge and perception about sepsis. Crit Care 2004;8:R409-13.
5. Levy MM, Fink MP, Marshall JC, Abraham E, Angus D, Cook D, et al. SCCM/ ESICM/ACCP/ATS/SIS. 2001 SCCM/ESICM/ACCP/ATS/SIS International Sepsis Definitions Conference. Crit Care Med 2003;31:1250-6.
6. Angus DC, van der Poll T. Severe sepsis and septic shock. N Engl J Med 2013;369:840-51.
7. Knaus WA, Draper EA, Wagner DP, Zimmerman JE. APACHE II: A severity of disease classification system. Crit Care Med 1985;13:818-29.
8. Le Gall JR, Neumann A, Hemery F, Bleriot JP, Fulgencio JP, Garrigues B, et al. Mortality prediction using SAPS II: An update for French intensive care units. Crit Care 2005;9:R645-52.
9. Vincent JL, de Mendonça A, Cantraine F, Moreno R, Takala J, Suter PM, et al. Use of the SOFA score to assess the incidence of organ dysfunction/failure in intensive care units: Results of a multicenter, prospective study. Working group on "sepsis-related problems" of the European Society of Intensive Care Medicine. Crit Care Med 1998;26:1793-800.
10. Rello J, Rodriguez A, Lisboa T, Gallego M, Lujan M, Wunderink R. PIRO score for community-acquired pneumonia: A new prediction rule for assessment of severity in intensive care unit patients with community-acquired pneumonia. Crit Care Med 2009;37:456-62.
11. Lisboa T, Diaz E, Sa-Borges M, Socias A, Sole-Violan J, Rodríguez A, et al. The ventilator-associated pneumonia PIRO score: A tool for predicting ICU mortality and health-care resources use in ventilatorassociated pneumonia. Chest 2008;134:1208-16.
12. Howell MD, Talmor D, Schuetz P, Hunziker S, Jones AE, Shapiro NI. Proof of principle: The predisposition, infection, response, organ failure sepsis staging system. Crit Care Med 2011;39:322-7.
13. Rubulotta F, Marshall JC, Ramsay G, Nelson D, Levy M, Williams M. Predisposition, insult/infection, response, and organ dysfunction: A new model for staging severe sepsis. Crit Care Med 2009;37:1329-35.
14. Moreno RP, Metnitz B, Adler L, Hoechtl A, Bauer P, Metnitz PG; SAPS 3 Investigators. Sepsis mortality prediction based on predisposition, infection and response. Intensive Care Med 2008;34:496-504.
15. Granja C, Póvoa P, Lobo C, Teixeira-Pinto A, Carneiro A, Costa-Pereira A. The predisposition, infection, response and organ failure (Piro) sepsis classification system: Results of hospital mortality using a novel concept and methodological approach. PLoS One 2013;8:e53885.
16. Nguyen HB, Van Ginkel C, Batech M, Banta J, Corbett SW. Comparison of Predisposition, Insult/Infection, Response, and Organ dysfunction, Acute Physiology and Chronic Health Evaluation II, and Mortality in Emergency Department Sepsis in patients meeting criteria for early goal-directed therapy and the severe sepsis resuscitation bundle. J Crit Care 2012;27:362-9.
17. Chen YX, Li CS. Evaluation of community-acquired sepsis by PIRO system in the emergency department. Intern Emerg Med 2013;8:521-7.
18. Cardoso T, Teixeira-Pinto A, Rodrigues PP, Aragão I, Costa-Pereira A, Sarmento AE. Predisposition, insult/infection, response and organ dysfunction (PIRO): A pilot clinical staging system for hospital mortality in patients with infection. PLoS One 2013;8:e70806.
19. Horan TC, Andrus M, Dudeck MA. CDC/NHSN surveillance definition of health care-associated infection and criteria for specific types of infections in the acute care setting. Am J Infect Control 2008;36:309-32.