메뉴 건너뛰기




Volumn 18, Issue 11, 2015, Pages 874-885

Cost-utility of fingolimod compared with dimethyl fumarate in highly active relapsing-remitting multiple sclerosis (RRMS) in England

Author keywords

Cost effectiveness; Cost utility; Dimethyl fumarate; Fingolimod; Highly active relapsing remitting multiple sclerosis; Multiple sclerosis

Indexed keywords

FINGOLIMOD; FUMARIC ACID DIMETHYL ESTER; PLACEBO; IMMUNOSUPPRESSIVE AGENT;

EID: 84945161927     PISSN: 13696998     EISSN: 1941837X     Source Type: Journal    
DOI: 10.3111/13696998.2015.1056794     Document Type: Article
Times cited : (22)

References (56)
  • 2
    • 0029913882 scopus 로고    scopus 로고
    • Defining the clinical course of multiple sclerosis: Results of an international survey. National multiple sclerosis society (USA) Advisory committee on clinical trials of new agents in multiple sclerosis
    • Lublin FD, Reingold SC. Defining the clinical course of multiple sclerosis: results of an international survey. National Multiple Sclerosis Society (USA) Advisory Committee on Clinical Trials of New Agents in Multiple Sclerosis. Neurology 1996;46:907-11
    • (1996) Neurology , vol.46 , pp. 907-911
    • Lublin, F.D.1    Reingold, S.C.2
  • 3
    • 84866984858 scopus 로고    scopus 로고
    • Natural, innate improvements in multiple sclerosis disability
    • Tremlett H, Zhu F, Petkau J, et al. Natural, innate improvements in multiple sclerosis disability. Mult Scler 2012;18:1412-21
    • (2012) Mult Scler , vol.18 , pp. 1412-1421
    • Tremlett, H.1    Zhu, F.2    Petkau, J.3
  • 4
    • 84884581173 scopus 로고    scopus 로고
    • Incidence and prevalence of multiple sclerosis in Europe: A systematic review
    • Kingwell E, Marriott JJ, Jette N, et al. Incidence and prevalence of multiple sclerosis in Europe: a systematic review. BMC Neurol 2013;13:128
    • (2013) BMC Neurol , vol.13 , pp. 128
    • Kingwell, E.1    Marriott, J.J.2    Jette, N.3
  • 5
    • 84891833705 scopus 로고    scopus 로고
    • Incidence and prevalence of multiple sclerosis in the UK 1990-2010: A descriptive study in the general practice research database
    • Mackenzie IS, Morant SV, Bloomfield GA, et al. Incidence and prevalence of multiple sclerosis in the UK 1990-2010: a descriptive study in the General Practice Research Database. J Neurol Neurosurg Psychiatry 2014;85:76-84
    • (2014) J Neurol Neurosurg Psychiatry , vol.85 , pp. 76-84
    • Mackenzie, I.S.1    Morant, S.V.2    Bloomfield, G.A.3
  • 6
    • 33746316226 scopus 로고    scopus 로고
    • Costs and quality of life of patients with multiple sclerosis in Europe
    • Kobelt G, Berg J, Lindgren P, et al. Costs and quality of life of patients with multiple sclerosis in Europe. J Neurol Neurosurg Psychiatry 2006;77:918-26
    • (2006) J Neurol Neurosurg Psychiatry , vol.77 , pp. 918-926
    • Kobelt, G.1    Berg, J.2    Lindgren, P.3
  • 7
    • 51949117761 scopus 로고    scopus 로고
    • Multiple sclerosis in the UK: Service use, costs, quality of life and disability
    • McCrone P, Heslin M, Knapp M, et al. Multiple sclerosis in the UK: service use, costs, quality of life and disability. Pharmacoeconomics 2008;26:847-60
    • (2008) Pharmacoeconomics , vol.26 , pp. 847-860
    • McCrone, P.1    Heslin, M.2    Knapp, M.3
  • 8
    • 84906020064 scopus 로고    scopus 로고
    • Multiple sclerosis: Current knowledge and future outlook
    • Kamm CP, Uitdehaag BM, Polman CH. Multiple sclerosis: Current knowledge and future outlook. Eur Neurol 2014;72:132-41
    • (2014) Eur Neurol , vol.72 , pp. 132-141
    • Kamm, C.P.1    Uitdehaag, B.M.2    Polman, C.H.3
  • 9
    • 84905101925 scopus 로고    scopus 로고
    • Accessed September 8, 2014
    • electronic Medicines Compendium (eMC). TYSABRI 300 mg concentrate for solution for infusion, 2013. https://www.medicines.org.uk/emc/medicine/18447. Accessed September 8, 2014
    • (2013) TYSABRI 300 Mg Concentrate for Solution for Infusion
  • 10
    • 84905119280 scopus 로고    scopus 로고
    • Accessed September 8, 2014
    • electronic Medicines Compendium (eMC). Gilenya 0.5mg hard capsules, 2014. http://www.medicines.org.uk/emc/medicine/24443/SPC/. Accessed September 8, 2014
    • (2014) Gilenya 0.5mg Hard Capsules
  • 11
    • 76149093586 scopus 로고    scopus 로고
    • A placebo-controlled trial of oral fingolimod in relapsing multiple sclerosis
    • Kappos L, Radue E, O'Connor P, et al. A placebo-controlled trial of oral fingolimod in relapsing multiple sclerosis. N Engl J Med 2010;362:387-401
    • (2010) N Engl J Med , vol.362 , pp. 387-401
    • Kappos, L.1    Radue, E.2    O'Connor, P.3
  • 12
    • 84901197534 scopus 로고    scopus 로고
    • Safety and efficacy of fingolimod in patients with relapsing-remitting multiple sclerosis (FREEDOMS II): A doubleblind, randomised, placebo-controlled, phase 3 trial
    • Calabresi PA, Radue EW, Goodin D, et al. Safety and efficacy of fingolimod in patients with relapsing-remitting multiple sclerosis (FREEDOMS II): a doubleblind, randomised, placebo-controlled, phase 3 trial. Lancet Neurol 2014;13:545-56
    • (2014) Lancet Neurol , vol.13 , pp. 545-556
    • Calabresi, P.A.1    Radue, E.W.2    Goodin, D.3
  • 13
    • 76149140914 scopus 로고    scopus 로고
    • Oral fingolimod or intramuscular interferon for relapsing multiple sclerosis
    • Cohen JA, Barkhof F, Comi G, et al. Oral fingolimod or intramuscular interferon for relapsing multiple sclerosis. N Engl J Med 2010;362:402-15
    • (2010) N Engl J Med , vol.362 , pp. 402-415
    • Cohen, J.A.1    Barkhof, F.2    Comi, G.3
  • 14
    • 80053533877 scopus 로고    scopus 로고
    • Randomized trial of oral teriflunomide for relapsing multiple sclerosis
    • O'Connor P, Wolinsky JS, Confavreux C, et al. Randomized trial of oral teriflunomide for relapsing multiple sclerosis. N Engl J Med 2011;365:1293-303
    • (2011) N Engl J Med , vol.365 , pp. 1293-1303
    • O'Connor, P.1    Wolinsky, J.S.2    Confavreux, C.3
  • 15
    • 84894271594 scopus 로고    scopus 로고
    • Oral teriflunomide for patients with relapsing multiple sclerosis (TOWER): A randomised, double-blind, placebocontrolled, phase 3 trial
    • Confavreux C, O'Connor P, Comi G, et al. Oral teriflunomide for patients with relapsing multiple sclerosis (TOWER): a randomised, double-blind, placebocontrolled, phase 3 trial. Lancet Neurol 2014;13:247-56
    • (2014) Lancet Neurol , vol.13 , pp. 247-256
    • Confavreux, C.1    O'Connor, P.2    Comi, G.3
  • 16
    • 84897022266 scopus 로고    scopus 로고
    • Teriflunomide versus subcutaneous interferon beta-1a in patients with relapsing multiple sclerosis: A randomised, controlled phase 3 trial
    • Vermersch P, Czlonkowska A, Grimaldi LM, et al. Teriflunomide versus subcutaneous interferon beta-1a in patients with relapsing multiple sclerosis: a randomised, controlled phase 3 trial. Mult Scler 2014;20:705-16
    • (2014) Mult Scler , vol.20 , pp. 705-716
    • Vermersch, P.1    Czlonkowska, A.2    Grimaldi, L.M.3
  • 17
    • 84866423965 scopus 로고    scopus 로고
    • Placebo-controlled phase 3 study of oral BG-12 for relapsing multiple sclerosis
    • Gold R, Kappos L, Arnold DL, et al. Placebo-controlled phase 3 study of oral BG-12 for relapsing multiple sclerosis. N Engl J Med 2012;367:1098-107
    • (2012) N Engl J Med , vol.367 , pp. 1098-1107
    • Gold, R.1    Kappos, L.2    Arnold, D.L.3
  • 18
    • 84866355653 scopus 로고    scopus 로고
    • Placebo-controlled phase 3 study of oral BG-12 or glatiramer in multiple sclerosis
    • Fox RJ, Miller DH, Phillips JT, et al. Placebo-controlled phase 3 study of oral BG-12 or glatiramer in multiple sclerosis. N Engl J Med 2012;367:1087-97
    • (2012) N Engl J Med , vol.367 , pp. 1087-1097
    • Fox, R.J.1    Miller, D.H.2    Phillips, J.T.3
  • 19
    • 84922082704 scopus 로고    scopus 로고
    • Cost effectiveness of fingolimod, teriflunomide, dimethyl fumarate and intramuscular interferon-beta in relapsing-remitting multiple sclerosis
    • Zhang X, Hay JW, Niu X. Cost effectiveness of fingolimod, teriflunomide, dimethyl fumarate and intramuscular interferon-beta in relapsing-remitting multiple sclerosis. CNS drugs 2015;29:71-81
    • (2015) CNS Drugs , vol.29 , pp. 71-81
    • Zhang, X.1    Hay, J.W.2    Niu, X.3
  • 21
    • 84945118469 scopus 로고    scopus 로고
    • Accessed August 27, 2014
    • electronic Medicines Compendium (eMC). Tecfidera 240 mg gastro-resistant hard capsules, 2014. http://www.medicines.org.uk/emc/medicine/28592. Accessed August 27, 2014
    • (2014) Tecfidera 240 Mg Gastro-resistant Hard Capsules
  • 22
    • 84945121646 scopus 로고    scopus 로고
    • Accessed September 22, 2014
    • electronic Medicines Compendium (eMC). AUBAGIO 14 mg film-coated tablets, 2014. http://www.medicines.org.uk/emc/medicine/28533. Accessed September 22, 2014
    • (2014) AUBAGIO 14 Mg Film-coated Tablets
  • 25
    • 85043144930 scopus 로고    scopus 로고
    • Efficacy of fingolimod in pre-treated patients with disease activity: Pooled analyses of FREEDOMS and FREEDOMS II (P3.174)
    • P3.174
    • Bergvall N, Sfikas N, Chin P, et al. Efficacy of fingolimod in pre-treated patients with disease activity: Pooled analyses of FREEDOMS and FREEDOMS II (P3.174). Neurology 2014;82(10 Supplement):P3.174
    • (2014) Neurology , vol.82 , Issue.10
    • Bergvall, N.1    Sfikas, N.2    Chin, P.3
  • 28
    • 72449125358 scopus 로고    scopus 로고
    • Multiple sclerosis risk sharing scheme: Two year results of clinical cohort study with historical comparator
    • Boggild M, Palace J, Barton P, et al. Multiple sclerosis risk sharing scheme: two year results of clinical cohort study with historical comparator. BMJ 2009;339:b4677
    • (2009) BMJ , vol.339 , pp. b4677
    • Boggild, M.1    Palace, J.2    Barton, P.3
  • 32
    • 84945135726 scopus 로고    scopus 로고
    • Manufacturer submission of evidence. London, UK: National Institute for Health and Care Excellence: TA312
    • Genzyme. Alemtuzumab for the treatment of relapsing remitting multiple sclerosis in adults. Manufacturer submission of evidence. London, UK: National Institute for Health and Care Excellence: TA312; 2013
    • (2013) Alemtuzumab for the Treatment of Relapsing Remitting Multiple Sclerosis in Adults
  • 33
  • 34
    • 84870958115 scopus 로고    scopus 로고
    • Manufacturer submission of evidence. London, UK: National Institute for Health and Clinical Excellence: TA254
    • Novartis Pharmaceuticals UK Ltd. Fingolimod for the treatment of relapsingremitting multiple sclerosis in adults. Manufacturer submission of evidence. London, UK: National Institute for Health and Clinical Excellence: TA254; 2011
    • (2011) Fingolimod for the Treatment of Relapsingremitting Multiple Sclerosis in Adults
  • 36
    • 84945123615 scopus 로고    scopus 로고
    • Accessed October 22, 2014
    • Office for National Statistics. England and Wales, interim life tables, 1980-82 to 2010-2012, 2013. http://www.ons.gov.uk/ons/rel/lifetables/interim-lifetables/2010-2012/rft-ew.xls. Accessed October 22, 2014
    • (2013) England and Wales, Interim Life Tables, 1980-82 to 2010-2012
  • 37
    • 0030627540 scopus 로고    scopus 로고
    • Long-term survival experience of patients with multiple sclerosis
    • Pokorski RJ. Long-term survival experience of patients with multiple sclerosis. J Insur Med 1997;29:101-6
    • (1997) J Insur Med , vol.29 , pp. 101-106
    • Pokorski, R.J.1
  • 38
    • 0026780512 scopus 로고
    • Life expectancy in patients attending multiple sclerosis clinics
    • Sadovnick AD, Ebers GC, Wilson RW, et al. Life expectancy in patients attending multiple sclerosis clinics. Neurology 1992;42:991
    • (1992) Neurology , vol.42 , pp. 991
    • Sadovnick, A.D.1    Ebers, G.C.2    Wilson, R.W.3
  • 39
    • 0024504359 scopus 로고
    • The natural history of multiple sclerosis: A geographically based study. I. Clinical course and disability
    • Weinshenker BG, Bass B, Rice GP, et al. The natural history of multiple sclerosis: a geographically based study. I. Clinical course and disability. Brain 1989;112(Pt 1):133-46
    • (1989) Brain , vol.112 , pp. 133-146
    • Weinshenker, B.G.1    Bass, B.2    Rice, G.P.3
  • 40
    • 84887044784 scopus 로고    scopus 로고
    • London, UK: Association of British Neurologists
    • Association of British Neurologists. Guidelines for prescribing in multiple sclerosis. London, UK: Association of British Neurologists; 2009
    • (2009) Guidelines for Prescribing in Multiple Sclerosis
  • 41
    • 68349141120 scopus 로고    scopus 로고
    • The half-cycle correction: Banish rather than explain it
    • Barendregt JJ. The half-cycle correction: banish rather than explain it. Med Decis Making 2009;29:500-2
    • (2009) Med Decis Making , vol.29 , pp. 500-502
    • Barendregt, J.J.1
  • 45
    • 34748843196 scopus 로고    scopus 로고
    • The distribution of the cost of multiple sclerosis in the UK: How do costs vary by illness severity?
    • Tyas D, Kerrigan J, Russell N, et al. The distribution of the cost of multiple sclerosis in the UK: how do costs vary by illness severity? Value Health 2007;10:386-9
    • (2007) Value Health , vol.10 , pp. 386-389
    • Tyas, D.1    Kerrigan, J.2    Russell, N.3
  • 46
    • 33846506747 scopus 로고    scopus 로고
    • The effect of disease, functional status, and relapses on the utility of people with multiple sclerosis in the UK
    • Orme M, Kerrigan J, Tyas D. The effect of disease, functional status, and relapses on the utility of people with multiple sclerosis in the UK. Value Health 2007;10:54-60
    • (2007) Value Health , vol.10 , pp. 54-60
    • Orme, M.1    Kerrigan, J.2    Tyas, D.3
  • 48
    • 84892884652 scopus 로고    scopus 로고
    • UK multiple sclerosis risk-sharing scheme: A new natural history dataset and an improved Markov model
    • Palace J, Bregenzer T, Tremlett H, et al. UK multiple sclerosis risk-sharing scheme: a new natural history dataset and an improved Markov model. BMJ Open 2014;4:e004073
    • (2014) BMJ Open , vol.4 , pp. e004073
    • Palace, J.1    Bregenzer, T.2    Tremlett, H.3
  • 50
    • 84945125030 scopus 로고    scopus 로고
    • Persistence with fingolimod versus dimethyl fumarate in patients with multiple sclerosis: A retrospective analysis using US open and closed data sources
    • September 10-13, 2014, Boston, MA
    • Bergvall N, Lahoz R, Nazareth T, et al. Persistence with fingolimod versus dimethyl fumarate in patients with multiple sclerosis: a retrospective analysis using US open and closed data sources. Poster presented at the Joint ECTRIMS/ACTRIMS meeting, September 10-13, 2014, Boston, MA. 2014:P289
    • (2014) Poster Presented at the Joint ECTRIMS/ACTRIMS Meeting , pp. 289
    • Bergvall, N.1    Lahoz, R.2    Nazareth, T.3
  • 51
    • 84945165312 scopus 로고    scopus 로고
    • Comparative tolerability and efficacy of dimethyl fumarate and fingolimod in multiple sclerosis
    • September 10-13, 2014, Boston, MA, USA
    • Cohn S, Bermel RA, Hara-Cleaver C, et al. Comparative Tolerability and Efficacy of Dimethyl Fumarate And Fingolimod in Multiple Sclerosis. Poster presented at the Joint ECTRIMS/ACTRIMS meeting, September 10-13, 2014, Boston, MA, USA. 2014. p 300
    • (2014) Poster Presented at the Joint ECTRIMS/ACTRIMS Meeting , pp. 300
    • Cohn, S.1    Bermel, R.A.2    Hara-Cleaver, C.3
  • 53
    • 33644695375 scopus 로고    scopus 로고
    • The impact of agerelated macular degeneration on health status utility values
    • Espallargues M, Czoski-Murray CJ, Bansback NJ, et al. The impact of agerelated macular degeneration on health status utility values. Invest Ophthalmol Vis Sci 2005;46:4016-23
    • (2005) Invest Ophthalmol Vis Sci , vol.46 , pp. 4016-4023
    • Espallargues, M.1    Czoski-Murray, C.J.2    Bansback, N.J.3
  • 54
    • 27844487451 scopus 로고    scopus 로고
    • An investigation into the empirical validity of the EQ-5D and SF-6D based on hypothetical preferences in a general population
    • Petrou S, Hockley C. An investigation into the empirical validity of the EQ-5D and SF-6D based on hypothetical preferences in a general population. Health Econ 2005;14:1169-89
    • (2005) Health Econ , vol.14 , pp. 1169-1189
    • Petrou, S.1    Hockley, C.2
  • 55
    • 27744569367 scopus 로고    scopus 로고
    • The routine collation of health outcomes data from hospital treated subjects in the health outcomes data repository (HODaR): Descriptive analysis from the first 20,000 subjects
    • Currie CJ, McEwan P, Peters JR, et al. The routine collation of health outcomes data from hospital treated subjects in the Health Outcomes Data Repository (HODaR): descriptive analysis from the first 20,000 subjects. Value Health 2005;8:581-90
    • (2005) Value Health , vol.8 , pp. 581-590
    • Currie, C.J.1    McEwan, P.2    Peters, J.R.3
  • 56
    • 33748558111 scopus 로고    scopus 로고
    • Health state utilities for metastatic breast cancer
    • Lloyd A, Nafees B, Narewska J, et al. Health state utilities for metastatic breast cancer. Br J Cancer 2006;95:683-90
    • (2006) Br J Cancer , vol.95 , pp. 683-690
    • Lloyd, A.1    Nafees, B.2    Narewska, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.