-
1
-
-
0024847290
-
What is synergy?
-
Berenbaum, M. C. (1989). What is synergy? Pharmacol. Rev. 41, 93-141.
-
(1989)
Pharmacol. Rev
, vol.41
, pp. 93-141
-
-
Berenbaum, M.C.1
-
2
-
-
84946384873
-
The toxicity of poisons applied jointly1
-
Bliss, C. I. (1939). The toxicity of poisons applied jointly1. Ann. Appl. Biol. 26, 585-615. doi: 10.1111/j.1744-7348.1939.tb06990.x
-
(1939)
Ann. Appl. Biol
, vol.26
, pp. 585-615
-
-
Bliss, C.I.1
-
3
-
-
84886588058
-
'Drug synergy-mechanisms and methods of analysis,'
-
ed. B. Acree (Rijeka: InTech)
-
Breitinger, H.-G. (2012). "Drug synergy-mechanisms and methods of analysis," in Toxicity and Drug Testing, ed B. Acree (Rijeka: InTech), 143-166.
-
(2012)
Toxicity and Drug Testing
, pp. 143-166
-
-
Breitinger, H.-G.1
-
4
-
-
84911860811
-
Binding characteristics and synergistic effects of bacterial expansins on cellulosic and hemicellulosic substrates
-
Bunterngsook, B., Eurwilaichitr, L., Thamchaipenet, A., and Champreda, V. (2015). Binding characteristics and synergistic effects of bacterial expansins on cellulosic and hemicellulosic substrates. Bioresour. Technol. 176, 129-135. doi: 10.1016/j.biortech.2014.11.042
-
(2015)
Bioresour. Technol
, vol.176
, pp. 129-135
-
-
Bunterngsook, B.1
Eurwilaichitr, L.2
Thamchaipenet, A.3
Champreda, V.4
-
5
-
-
84928790670
-
Systematic discovery of drug interaction mechanisms
-
Chevereau, G., and Bollenbach, T. (2015). Systematic discovery of drug interaction mechanisms. Mol. Syst. Biol. 11:807. doi: 10.15252/msb.20156098
-
(2015)
Mol. Syst. Biol
, vol.11
, pp. 807
-
-
Chevereau, G.1
Bollenbach, T.2
-
6
-
-
33748794547
-
Theoretical basis, experimental design, and computerized simulation of synergism and antagonism in drug combination studies
-
Chou, T.-C. (2006). Theoretical basis, experimental design, and computerized simulation of synergism and antagonism in drug combination studies. Pharmacol. Rev. 58, 621-681. doi: 10.1124/pr.58.3.10
-
(2006)
Pharmacol. Rev
, vol.58
, pp. 621-681
-
-
Chou, T.-C.1
-
7
-
-
76549129820
-
Drug combination studies and their synergy quantification using the Chou-Talalay method
-
Chou, T.-C. (2010). Drug combination studies and their synergy quantification using the Chou-Talalay method. Cancer Res. 70, 440-446. doi: 10.1158/0008-5472.CAN-09-1947
-
(2010)
Cancer Res
, vol.70
, pp. 440-446
-
-
Chou, T.-C.1
-
8
-
-
80855124963
-
Systematic exploration of synergistic drug pairs
-
Cokol, M., Chua, H. N., Tasan, M., Mutlu, B., Weinstein, Z. B., Suzuki, Y., et al. (2011). Systematic exploration of synergistic drug pairs. Mol. Syst. Biol. 7:544. doi: 10.1038/msb.2011.71
-
(2011)
Mol. Syst. Biol
, vol.7
, pp. 544
-
-
Cokol, M.1
Chua, H.N.2
Tasan, M.3
Mutlu, B.4
Weinstein, Z.B.5
Suzuki, Y.6
-
9
-
-
55649090564
-
Quantifying the evidence for ecological synergies
-
Darling, E. S., and Côté, I. M. (2008). Quantifying the evidence for ecological synergies. Ecol. Lett. 11, 1278-1286. doi: 10.1111/j.1461-0248.2008.01243.x
-
(2008)
Ecol. Lett
, vol.11
, pp. 1278-1286
-
-
Darling, E.S.1
Côté, I.M.2
-
10
-
-
0028991020
-
Assessment of the combined effects of substances: the relationship between concentration addition and independent action
-
Drescher, K., and Boedeker, W. (1995). Assessment of the combined effects of substances: the relationship between concentration addition and independent action. Biometrics 51, 716-730. doi: 10.2307/2532957
-
(1995)
Biometrics
, vol.51
, pp. 716-730
-
-
Drescher, K.1
Boedeker, W.2
-
11
-
-
0033118758
-
CombiTool-a new computer program for analyzing combination experiments with biologically active agents
-
Dressler, V., Müller, G., and Sühnel, J. (1999). CombiTool-a new computer program for analyzing combination experiments with biologically active agents. Comput. Biomed. Res. Int. J. 32, 145-160. doi: 10.1006/cbmr.1999.1509
-
(1999)
Comput. Biomed. Res. Int. J
, vol.32
, pp. 145-160
-
-
Dressler, V.1
Müller, G.2
Sühnel, J.3
-
12
-
-
33747620519
-
Systems biology and combination therapy in the quest for clinical efficacy
-
Fitzgerald, J. B., Schoeberl, B., Nielsen, U. B., and Sorger, P. K. (2006). Systems biology and combination therapy in the quest for clinical efficacy. Nat. Chem. Biol. 2, 458-466. doi: 10.1038/nchembio817
-
(2006)
Nat. Chem. Biol
, vol.2
, pp. 458-466
-
-
Fitzgerald, J.B.1
Schoeberl, B.2
Nielsen, U.B.3
Sorger, P.K.4
-
13
-
-
34247177620
-
A mathematical approach to study combined effects of toxicants in vitro: evaluation of the Bliss independence criterion and the Loewe additivity model
-
Goldoni, M., and Johansson, C. (2007). A mathematical approach to study combined effects of toxicants in vitro: evaluation of the Bliss independence criterion and the Loewe additivity model. Toxicol. In Vitro 21, 759-769. doi: 10.1016/j.tiv.2007.03.003
-
(2007)
Toxicol. In Vitro
, vol.21
, pp. 759-769
-
-
Goldoni, M.1
Johansson, C.2
-
14
-
-
0002303704
-
Consensus on concepts and terminology for combined action assessment: the saariselkä agreement
-
Greco, W., Unkelbach, H.-D., Pöch, G., Sühnel, J., Kundi, M., and Bödeker, W. (1992). Consensus on concepts and terminology for combined action assessment: the saariselkä agreement. Arch. Complex Environ. Stud. 4, 65-69.
-
(1992)
Arch. Complex Environ. Stud
, vol.4
, pp. 65-69
-
-
Greco, W.1
Unkelbach, H.-D.2
Pöch, G.3
Sühnel, J.4
Kundi, M.5
Bödeker, W.6
-
15
-
-
0029036955
-
The search for synergy: a critical review from a response surface perspective
-
Greco, W. R., Bravo, G., and Parsons, J. C. (1995). The search for synergy: a critical review from a response surface perspective. Pharmacol. Rev. 47, 331-385.
-
(1995)
Pharmacol. Rev
, vol.47
, pp. 331-385
-
-
Greco, W.R.1
Bravo, G.2
Parsons, J.C.3
-
16
-
-
80053500301
-
The enhancement of enzymatic hydrolysis of lignocellulosic substrates by the addition of accessory enzymes such as xylanase: is it an additive or synergistic effect?
-
Hu, J., Arantes, V., and Saddler, J. N. (2011). The enhancement of enzymatic hydrolysis of lignocellulosic substrates by the addition of accessory enzymes such as xylanase: is it an additive or synergistic effect? Biotechnol. Biofuels 4:36. doi: 10.1186/1754-6834-4-36
-
(2011)
Biotechnol. Biofuels
, vol.4
, pp. 36
-
-
Hu, J.1
Arantes, V.2
Saddler, J.N.3
-
17
-
-
84904161049
-
A pragmatic definition of therapeutic synergy suitable for clinically relevant in vitro multicompound analyses
-
Kashif, M., Andersson, C., Åberg, M., Nygren, P., Sjöblom, T., Hammerling, U., et al. (2014). A pragmatic definition of therapeutic synergy suitable for clinically relevant in vitro multicompound analyses. Mol. Cancer Ther. 13, 1964-1976. doi: 10.1158/1535-7163.MCT-13-0430
-
(2014)
Mol. Cancer Ther
, vol.13
, pp. 1964-1976
-
-
Kashif, M.1
Andersson, C.2
Åberg, M.3
Nygren, P.4
Sjöblom, T.5
Hammerling, U.6
-
18
-
-
33845502742
-
A generalized response surface model with varying relative potency for assessing drug interaction
-
Kong, M., and Lee, J. J. (2006). A generalized response surface model with varying relative potency for assessing drug interaction. Biometrics 62, 986-995. doi: 10.1111/j.1541-0420.2006.00579.x
-
(2006)
Biometrics
, vol.62
, pp. 986-995
-
-
Kong, M.1
Lee, J.J.2
-
19
-
-
84922480274
-
A mechanistic theory to explain the efficacy of antiretroviral therapy
-
Laskey, S. B., and Siliciano, R. F. (2014). A mechanistic theory to explain the efficacy of antiretroviral therapy. Nat. Rev. Microbiol. 12, 772-780. doi: 10.1038/nrmicro3351
-
(2014)
Nat. Rev. Microbiol
, vol.12
, pp. 772-780
-
-
Laskey, S.B.1
Siliciano, R.F.2
-
20
-
-
34247897031
-
Interaction index and different methods for determining drug interaction in combination therapy
-
Lee, J. J., Kong, M., Ayers, G. D., and Lotan, R. (2007). Interaction index and different methods for determining drug interaction in combination therapy. J. Biopharm. Stat. 17, 461-480. doi: 10.1080/10543400701199593
-
(2007)
J. Biopharm. Stat
, vol.17
, pp. 461-480
-
-
Lee, J.J.1
Kong, M.2
Ayers, G.D.3
Lotan, R.4
-
21
-
-
77953336211
-
Drug interaction: focusing on response surface models
-
Lee, S.-I. (2010). Drug interaction: focusing on response surface models. Korean J. Anesthesiol. 58, 421-434. doi: 10.4097/kjae.2010.58.5.421
-
(2010)
Korean J. Anesthesiol
, vol.58
, pp. 421-434
-
-
Lee, S.-I.1
-
22
-
-
67650488269
-
Synergistic drug combinations tend to improve therapeutically relevant selectivity
-
Lehár, J., Krueger, A. S., Avery, W., Heilbut, A. M., Johansen, L. M., Price, E. R., et al. (2009). Synergistic drug combinations tend to improve therapeutically relevant selectivity. Nat. Biotechnol. 27, 659-666. doi: 10.1038/nbt.1549
-
(2009)
Nat. Biotechnol
, vol.27
, pp. 659-666
-
-
Lehár, J.1
Krueger, A.S.2
Avery, W.3
Heilbut, A.M.4
Johansen, L.M.5
Price, E.R.6
-
23
-
-
0001663843
-
The problem of synergism and antagonism of combined drugs
-
Loewe, S. (1953). The problem of synergism and antagonism of combined drugs. Arzneimittelforschung 3, 285-290.
-
(1953)
Arzneimittelforschung
, vol.3
, pp. 285-290
-
-
Loewe, S.1
-
24
-
-
84885811004
-
Drug synergy screen and network modeling in dedifferentiated liposarcoma identifies CDK4 and IGF1R as synergistic drug targets
-
Miller, M. L., Molinelli, E. J., Nair, J. S., Sheikh, T., Samy, R., Jing, X., et al. (2013). Drug synergy screen and network modeling in dedifferentiated liposarcoma identifies CDK4 and IGF1R as synergistic drug targets. Sci. Signal. 6:ra85. doi: 10.1126/scisignal.2004014
-
(2013)
Sci. Signal
, vol.6
-
-
Miller, M.L.1
Molinelli, E.J.2
Nair, J.S.3
Sheikh, T.4
Samy, R.5
Jing, X.6
-
25
-
-
84926418142
-
Reconceptualizing synergism and antagonism among multiple stressors
-
Piggott, J. J., Townsend, C. R., and Matthaei, C. D. (2015). Reconceptualizing synergism and antagonism among multiple stressors. Ecol. Evol. 5, 1538-1547. doi: 10.1002/ece3.1465
-
(2015)
Ecol. Evol
, vol.5
, pp. 1538-1547
-
-
Piggott, J.J.1
Townsend, C.R.2
Matthaei, C.D.3
-
26
-
-
49949097479
-
Additivity versus synergy: a theoretical analysis of implications for anesthetic mechanisms
-
Shafer, S. L., Hendrickx, J. F., Flood, P., Sonner, J., and Eger, E. I. II. (2008). Additivity versus synergy: a theoretical analysis of implications for anesthetic mechanisms. Anesth. Analg. 107, 507-524. doi: 10.1213/ane.0b013e31817b7140
-
(2008)
Anesth. Analg
, vol.107
, pp. 507-524
-
-
Shafer, S.L.1
Hendrickx, J.F.2
Flood, P.3
Sonner, J.4
Eger, E.I.5
-
27
-
-
84921850405
-
Searching for synergy in silico, in vitro and in vivo
-
Sucher, N. J. (2014). Searching for synergy in silico, in vitro and in vivo. Synergy 1, 30-43. doi: 10.1016/j.synres.2014.07.004
-
(2014)
Synergy
, vol.1
, pp. 30-43
-
-
Sucher, N.J.1
-
28
-
-
33749007441
-
An overview of drug combination analysis with isobolograms
-
Tallarida, R. J. (2006). An overview of drug combination analysis with isobolograms. J. Pharmacol. Exp. Ther. 319, 1-7. doi: 10.1124/jpet.106.104117
-
(2006)
J. Pharmacol. Exp. Ther
, vol.319
, pp. 1-7
-
-
Tallarida, R.J.1
-
29
-
-
33645396484
-
Functional classification of drugs by properties of their pairwise interactions
-
Yeh, P., Tschumi, A. I., and Kishony, R. (2006). Functional classification of drugs by properties of their pairwise interactions. Nat. Genet. 38, 489-494. doi: 10.1038/ng1755
-
(2006)
Nat. Genet
, vol.38
, pp. 489-494
-
-
Yeh, P.1
Tschumi, A.I.2
Kishony, R.3
-
30
-
-
84920252183
-
Impact of xylan on synergistic effects of xylanases and cellulases in enzymatic hydrolysis of lignocelluloses
-
Zhang, J., and Viikari, L. (2014). Impact of xylan on synergistic effects of xylanases and cellulases in enzymatic hydrolysis of lignocelluloses. Appl. Biochem. Biotechnol. 174, 1393-1402. doi: 10.1007/s12010-014-1140-7
-
(2014)
Appl. Biochem. Biotechnol
, vol.174
, pp. 1393-1402
-
-
Zhang, J.1
Viikari, L.2
-
31
-
-
77954503442
-
Comparison of methods for evaluating drug-drug interaction
-
Zhao, L., Au, J. L., and Wientjes, M. G. (2010). Comparison of methods for evaluating drug-drug interaction. Front. Biosci. Elite Ed. 2, 241-249. doi: 10.2741/e86
-
(2010)
Front. Biosci. Elite Ed
, vol.2
, pp. 241-249
-
-
Zhao, L.1
Au, J.L.2
Wientjes, M.G.3
-
32
-
-
84902211438
-
A new bliss independence model to analyze drug combination data
-
Zhao, W., Sachsenmeier, K., Zhang, L., Sult, E., Hollingsworth, R. E., and Yang, H. (2014). A new bliss independence model to analyze drug combination data. J. Biomol. Screen. 19, 817-821. doi: 10.1177/1087057114521867
-
(2014)
J. Biomol. Screen
, vol.19
, pp. 817-821
-
-
Zhao, W.1
Sachsenmeier, K.2
Zhang, L.3
Sult, E.4
Hollingsworth, R.E.5
Yang, H.6
|