Cryptococcal meningoencephalitis relapse after an eight-year delay: an interplay of infection and immune reconstitution

International Journal of STD and AIDS

Volumn 26, Issue 12, 2015, Pages 912-914

  Katchanov, Juri ^a   Blechschmidt, Cristiane ^b   Nielsen, Kirsten ^c   Branding, Gordian ^a   Arastéh, Keikawus ^a   Tintelnot, Kathrin ^d   Meintjes, Graeme ^e   Boulware, David R ^f   Stocker, Hartmut ^a  

^a Vivantes Auguste Viktoria Klinikum   (Germany)

^b VIVANTES KLINIKUM NEUKÖLLN   (Germany)

^c UNIVERSITY OF MINNESOTA   (United States)

^d ROBERT KOCH INSTITUTE   (Germany)

^e UNIVERSITY OF CAPE TOWN   (South Africa)

^f UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

Author keywords

AIDS; antiretroviral therapy; CNS cryptococcosis; cryptococcal meningitis; Cryptococcus neoformans; HIV; immune restoration; IRIS; opportunistic infection

Indexed keywords

AMPHOTERICIN B LIPID COMPLEX; EFAVIRENZ; EMTRICITABINE; FLUCONAZOLE; FLUCYTOSINE; PREDNISOLONE; TENOFOVIR; ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; ANTIFUNGAL AGENT;

ADULT; ANTIBIOTIC PROPHYLAXIS; ANTIVIRAL THERAPY; ARTICLE; BRAIN BIOPSY; BRAIN EDEMA; CASE REPORT; CD4 LYMPHOCYTE COUNT; CEREBROSPINAL FLUID CYTOLOGY; CLINICAL EXAMINATION; CONTRAST ENHANCEMENT; CRYPTOCOCCAL MENINGITIS; CRYPTOCOCCAL MENINGOENCEPHALITIS; DIENCEPHALON; DISEASE COURSE; FILOBASIDIELLA; HEMIPARESIS; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; HUMAN TISSUE; IMMUNE RECONSTITUTION INFLAMMATORY SYNDROME; LYMPHOCYTE SUBPOPULATION; MALE; MENINGOENCEPHALITIS; MESENCEPHALON; MUSCLE STRENGTH; NEUROLOGIC EXAMINATION; NUCLEAR MAGNETIC RESONANCE IMAGING; PATIENT COMPLIANCE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RECURRENT INFECTION; RELAPSE; SEIZURE; SPASTICITY; SUBARACHNOID SPACE; TREATMENT REFUSAL; VIRUS LOAD; YEAST CELL; AIDS-RELATED OPPORTUNISTIC INFECTIONS; BIOPSY; BRAIN; CRYPTOCOCCUS NEOFORMANS; FEMALE; GENETICS; HIGHLY ACTIVE ANTIRETROVIRAL THERAPY; HIV INFECTIONS; ISOLATION AND PURIFICATION; MEDICATION COMPLIANCE; MENINGITIS, CRYPTOCOCCAL; PATHOLOGY; RECURRENT DISEASE; TREATMENT OUTCOME;

AIDS-RELATED OPPORTUNISTIC INFECTIONS; ANTI-HIV AGENTS; ANTIFUNGAL AGENTS; ANTIRETROVIRAL THERAPY, HIGHLY ACTIVE; BIOPSY; BRAIN; CRYPTOCOCCUS NEOFORMANS; FEMALE; FLUCONAZOLE; HIV INFECTIONS; HUMANS; IMMUNE RECONSTITUTION INFLAMMATORY SYNDROME; MALE; MEDICATION ADHERENCE; MENINGITIS, CRYPTOCOCCAL; RECURRENCE; TREATMENT OUTCOME;

EID: 84944554476     PISSN: 09564624     EISSN: 17581052     Source Type: Journal    
DOI: 10.1177/0956462414563630     Document Type: Article

References (3)

1. A.K.MusubireD.R.BoulwareD.B.Meya. Diagnosis and management of cryptococcal relapse. J AIDS Clin Res2013; pii: S3–003.
2. L.J.HaddowR.ColebundersG.Meintjes. International network for the study of HIV-associated IRIS (INSHI). Cryptococcal immune reconstitution inflammatory syndrome in HIV-1-infected individuals: proposed clinical case definitions. Lancet Infect Dis2010; 10: 791–802.
3. D.R.BoulwareD.B.MeyaT.L.Bergemann. Clinical features and serum biomarkers in HIV immune reconstitution inflammatory syndrome after Cryptococcal meningitis: a prospective cohort study. PLoS Med2010; 7: e1000384–e1000384.