-
1
-
-
84862317270
-
RNA interference trigger variants: Getting the most out of RNA for RNA interference-based therapeutics
-
Snead NM, Rossi JJ (2012) RNA interference trigger variants: getting the most out of RNA for RNA interference-based therapeutics. Nucleic Acid Ther 22:139-146
-
(2012)
Nucleic Acid Ther
, vol.22
, pp. 139-146
-
-
Snead, N.M.1
Rossi, J.J.2
-
2
-
-
84857784900
-
Progress toward in vivo use of siRNAs-II
-
Rettig GR, Behlke MA (2012) Progress toward in vivo use of siRNAs-II. Mol Ther 20:483-512
-
(2012)
Mol Ther
, vol.20
, pp. 483-512
-
-
Rettig, G.R.1
Behlke, M.A.2
-
3
-
-
79954580272
-
Current prospects for RNA interference-based therapies
-
Davidson BL, McCray PB Jr (2011) Current prospects for RNA interference-based therapies. Nat Rev Genet 12:329-340
-
(2011)
Nat Rev Genet
, vol.12
, pp. 329-340
-
-
Davidson, B.L.1
McCray, P.B.2
-
4
-
-
33646185371
-
RNAi-mediated gene silencing in nonhuman primates
-
Zimmermann TS, Lee AC, Akinc A, Bramlage B, Bumcrot D, Fedoruk MN, Harborth J, Heyes JA, Jeffs LB, John M, Judge AD, Lam K, McClintock K, Nechev LV, Palmer LR, Racie T, Rohl I, Seiffert S, Shanmugam S, Sood V, Soutschek J, Toudjarska I, Wheat AJ, Yaworski E, Zedalis W, Koteliansky V, Manoharan M, Vornlocher HP, MacLachlan I (2006) RNAi-mediated gene silencing in nonhuman primates. Nature 441:111-114
-
(2006)
Nature
, vol.441
, pp. 111-114
-
-
Zimmermann, T.S.1
Lee, A.C.2
Akinc, A.3
Bramlage, B.4
Bumcrot, D.5
Fedoruk, M.N.6
Harborth, J.7
Heyes, J.A.8
Jeffs, L.B.9
John, M.10
Judge, A.D.11
Lam, K.12
McClintock, K.13
Nechev, L.V.14
Palmer, L.R.15
Racie, T.16
Rohl, I.17
Seiffert, S.18
Shanmugam, S.19
Sood, V.20
Soutschek, J.21
Toudjarska, I.22
Wheat, A.J.23
Yaworski, E.24
Zedalis, W.25
Koteliansky, V.26
Manoharan, M.27
Vornlocher, H.P.28
MacLachlan, I.29
more..
-
5
-
-
77951132901
-
Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles
-
Davis ME, Zuckerman JE, Choi CH, Seligson D, Tolcher A, Alabi CA, Yen Y, Heidel JD, Ribas A (2010) Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles. Nature 464:1067-1070
-
(2010)
Nature
, vol.464
, pp. 1067-1070
-
-
Davis, M.E.1
Zuckerman, J.E.2
Choi, C.H.3
Seligson, D.4
Tolcher, A.5
Alabi, C.A.6
Yen, Y.7
Heidel, J.D.8
Ribas, A.9
-
7
-
-
70349971417
-
In vivo delivery of siRNA to immune cells by conjugation to a TLR9 agonist enhances antitumor immune responses
-
Kortylewski M, Swiderski P, Herrmann A, Wang L, Kowolik C, Kujawski M, Lee H, Scuto A, Liu Y, Yang C, Deng J, Soifer HS, Raubitschek A, Forman S, Rossi JJ, Pardoll DM, Jove R, Yu H (2009) In vivo delivery of siRNA to immune cells by conjugation to a TLR9 agonist enhances antitumor immune responses. Nat Biotechnol 27:925-932
-
(2009)
Nat Biotechnol
, vol.27
, pp. 925-932
-
-
Kortylewski, M.1
Swiderski, P.2
Herrmann, A.3
Wang, L.4
Kowolik, C.5
Kujawski, M.6
Lee, H.7
Scuto, A.8
Liu, Y.9
Yang, C.10
Deng, J.11
Soifer, H.S.12
Raubitschek, A.13
Forman, S.14
Rossi, J.J.15
Pardoll, D.M.16
Jove, R.17
Yu, H.18
-
8
-
-
84859489110
-
CpG still rocks! Update on an accidental drug
-
Krieg AM (2012) CpG still rocks! Update on an accidental drug. Nucleic Acid Ther 22:77-89
-
(2012)
Nucleic Acid Ther
, vol.22
, pp. 77-89
-
-
Krieg, A.M.1
-
9
-
-
77951260924
-
The role of patternrecognition receptors in innate immunity: Update on Toll-like receptors
-
Kawai T, Akira S (2010) The role of patternrecognition receptors in innate immunity: update on Toll-like receptors. Nat Immunol 11:373-384
-
(2010)
Nat Immunol
, vol.11
, pp. 373-384
-
-
Kawai, T.1
Akira, S.2
-
10
-
-
33747748975
-
Rational design and in vitro and in vivo delivery of Dicer substrate siRNA
-
Amarzguioui M, Lundberg P, Cantin E, Hagstrom J, Behlke MA, Rossi JJ (2006) Rational design and in vitro and in vivo delivery of Dicer substrate siRNA. Nat Protoc 1:508-517
-
(2006)
Nat Protoc
, vol.1
, pp. 508-517
-
-
Amarzguioui, M.1
Lundberg, P.2
Cantin, E.3
Hagstrom, J.4
Behlke, M.A.5
Rossi, J.J.6
-
11
-
-
84874449237
-
TLR9-mediated siRNA delivery for targeting of normal and malignant human hematopoietic cells in vivo
-
Zhang Q, Hossain DM, Nechaev S, Kozlowska A, Zhang W, Liu Y, Kowolik CM, Swiderski P, Rossi JJ, Forman S, Pal S, Bhatia R, Raubitschek A, Yu H, Kortylewski M (2013) TLR9-mediated siRNA delivery for targeting of normal and malignant human hematopoietic cells in vivo. Blood 121:1304-1315
-
(2013)
Blood
, vol.121
, pp. 1304-1315
-
-
Zhang, Q.1
Hossain, D.M.2
Nechaev, S.3
Kozlowska, A.4
Zhang, W.5
Liu, Y.6
Kowolik, C.M.7
Swiderski, P.8
Rossi, J.J.9
Forman, S.10
Pal, S.11
Bhatia, R.12
Raubitschek, A.13
Yu, H.14
Kortylewski, M.15
-
12
-
-
84885145424
-
Intracellular processing of immunostimulatory CpG-siRNA: Toll-like receptor 9 facilitates siRNA dicing and endosomal escape
-
Nechaev S, Gao C, Moreira D, Swiderski P, Jozwiak A, Kowolik CM, Zhou J, Armstrong B, Raubitschek A, Rossi JJ, Kortylewski M (2013) Intracellular processing of immunostimulatory CpG-siRNA: toll-like receptor 9 facilitates siRNA dicing and endosomal escape. J Control Release 170:307-315
-
(2013)
J Control Release
, vol.170
, pp. 307-315
-
-
Nechaev, S.1
Gao, C.2
Moreira, D.3
Swiderski, P.4
Jozwiak, A.5
Kowolik, C.M.6
Zhou, J.7
Armstrong, B.8
Raubitschek, A.9
Rossi, J.J.10
Kortylewski, M.11
-
13
-
-
84876416274
-
The rough endoplasmatic reticulum is a central nucleation site of siRNA-mediated RNA silencing
-
Stalder L, Heusermann W, Sokol L, Trojer D, Wirz J, Hean J, Fritzsche A, Aeschimann F, Pfanzagl V, Basselet P, Weiler J, Hintersteiner M, Morrissey DV, Meisner-Kober NC (2013) The rough endoplasmatic reticulum is a central nucleation site of siRNA-mediated RNA silencing. EMBO J 32:1115-1127
-
(2013)
EMBO J
, vol.32
, pp. 1115-1127
-
-
Stalder, L.1
Heusermann, W.2
Sokol, L.3
Trojer, D.4
Wirz, J.5
Hean, J.6
Fritzsche, A.7
Aeschimann, F.8
Pfanzagl, V.9
Basselet, P.10
Weiler, J.11
Hintersteiner, M.12
Morrissey, D.V.13
Meisner-Kober, N.C.14
-
14
-
-
84891769689
-
Leukemia cell-targeted STAT3 silencing and TLR9 triggering generate systemic antitumor immunity
-
Hossain DM, Dos Santos C, Zhang Q, Kozlowska A, Liu H, Gao C, Moreira D, Swiderski P, Jozwiak A, Kline J, Forman S, Bhatia R, Kuo YH, Kortylewski M (2014) Leukemia cell-targeted STAT3 silencing and TLR9 triggering generate systemic antitumor immunity. Blood 123:15-25
-
(2014)
Blood
, vol.123
, pp. 15-25
-
-
Hossain, D.M.1
Dos Santos, C.2
Zhang, Q.3
Kozlowska, A.4
Liu, H.5
Gao, C.6
Moreira, D.7
Swiderski, P.8
Jozwiak, A.9
Kline, J.10
Forman, S.11
Bhatia, R.12
Kuo, Y.H.13
Kortylewski, M.14
-
15
-
-
84861399789
-
S1PR1-STAT3 signaling is crucial for myeloid cell colonization at future metastatic sites
-
Deng J, Liu Y, Lee H, Herrmann A, Zhang W, Zhang C, Shen S, Priceman SJ, Kujawski M, Pal SK, Raubitschek A, Hoon DS, Forman S, Figlin RA, Liu J, Jove R, Yu H (2012) S1PR1-STAT3 signaling is crucial for myeloid cell colonization at future metastatic sites. Cancer Cell 21:642-654
-
(2012)
Cancer Cell
, vol.21
, pp. 642-654
-
-
Deng, J.1
Liu, Y.2
Lee, H.3
Herrmann, A.4
Zhang, W.5
Zhang, C.6
Shen, S.7
Priceman, S.J.8
Kujawski, M.9
Pal, S.K.10
Raubitschek, A.11
Hoon, D.S.12
Forman, S.13
Figlin, R.A.14
Liu, J.15
Jove, R.16
Yu, H.17
-
16
-
-
84938254969
-
TLR9 signaling through NF-κB/RELA and STAT3 promotes tumor-propagating potential of prostate cancer cells
-
Moreira D, Zhang Q, Hossain DM, Nechaev S, Li H, Kowolik CM, D’Apuzzo M, Forman S, Jones J, Pal SK, Kortylewski M (2015) TLR9 signaling through NF-κB/RELA and STAT3 promotes tumor-propagating potential of prostate cancer cells. Oncotarget 6:17302-17313
-
(2015)
Oncotarget
, vol.6
, pp. 17302-17313
-
-
Moreira, D.1
Zhang, Q.2
Hossain, D.M.3
Nechaev, S.4
Li, H.5
Kowolik, C.M.6
D’Apuzzo, M.7
Forman, S.8
Jones, J.9
Pal, S.K.10
Kortylewski, M.11
|