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Volumn 3, Issue 2, 2014, Pages 116-119

How old is "too old" for translational research?

Author keywords

Antiangiogenic agents; Elderly; Lung cancer; Tyrosine kinase inhibitors (TKIs)

Indexed keywords


EID: 84944357147     PISSN: 22186751     EISSN: 22264477     Source Type: Journal    
DOI: 10.3978/j.issn.2218-6751.2014.03.03     Document Type: Review
Times cited : (3)

References (28)
  • 3
    • 0033920730 scopus 로고    scopus 로고
    • Management of cancer in the older person: a practical approach
    • Balducci L, Extermann M. Management of cancer in the older person: a practical approach. Oncologist 2000;5:224-37.
    • (2000) Oncologist , vol.5 , pp. 224-237
    • Balducci, L.1    Extermann, M.2
  • 4
    • 34249774066 scopus 로고    scopus 로고
    • Comprehensive geriatric assessment for older patients with cancer
    • Extermann M, Hurria A. Comprehensive geriatric assessment for older patients with cancer. J Clin Oncol 2007;25:1824-31.
    • (2007) J Clin Oncol , vol.25 , pp. 1824-1831
    • Extermann, M.1    Hurria, A.2
  • 5
    • 17444373505 scopus 로고    scopus 로고
    • The abbreviated comprehensive geriatric assessment (aCGA): a retrospective analysis
    • Overcash JA, Beckstead J, Extermann M, et al. The abbreviated comprehensive geriatric assessment (aCGA): a retrospective analysis. Crit Rev Oncol Hematol 2005;54:129-36.
    • (2005) Crit Rev Oncol Hematol , vol.54 , pp. 129-136
    • Overcash, J.A.1    Beckstead, J.2    Extermann, M.3
  • 6
    • 80052964872 scopus 로고    scopus 로고
    • Carboplatin and weekly paclitaxel doublet chemotherapy compared with monotherapy in elderly patients with advanced non-smallcell lung cancer: IFCT-0501 randomised, phase 3 trial
    • Quoix E, Zalcman G, Oster JP, et al. Carboplatin and weekly paclitaxel doublet chemotherapy compared with monotherapy in elderly patients with advanced non-smallcell lung cancer: IFCT-0501 randomised, phase 3 trial. Lancet 2011;378:1079-88.
    • (2011) Lancet , vol.378 , pp. 1079-1088
    • Quoix, E.1    Zalcman, G.2    Oster, J.P.3
  • 7
    • 84890442079 scopus 로고    scopus 로고
    • Treatment outcomes in elderly with advanced-stage non-small cell lung cancer
    • Tam TC, Ho JC, Wong MK, et al. Treatment outcomes in elderly with advanced-stage non-small cell lung cancer. Lung 2013;191:645-54.
    • (2013) Lung , vol.191 , pp. 645-654
    • Tam, T.C.1    Ho, J.C.2    Wong, M.K.3
  • 9
    • 63049132774 scopus 로고    scopus 로고
    • First-line gefitinib for patients with advanced non-small-cell lung cancer harboring epidermal growth factor receptor mutations without indication for chemotherapy
    • Inoue A, Kobayashi K, Usui K, et al. First-line gefitinib for patients with advanced non-small-cell lung cancer harboring epidermal growth factor receptor mutations without indication for chemotherapy. J Clin Oncol 2009;27:1394-400.
    • (2009) J Clin Oncol , vol.27 , pp. 1394-1400
    • Inoue, A.1    Kobayashi, K.2    Usui, K.3
  • 10
    • 63049115966 scopus 로고    scopus 로고
    • The "lazarus response" in treatment-naive, poor performance status patients with non-small-cell lung cancer and epidermal growth factor receptor mutation
    • Langer CJ. The "lazarus response" in treatment-naive, poor performance status patients with non-small-cell lung cancer and epidermal growth factor receptor mutation. J Clin Oncol 2009;27:1350-4.
    • (2009) J Clin Oncol , vol.27 , pp. 1350-1354
    • Langer, C.J.1
  • 11
    • 79952185499 scopus 로고    scopus 로고
    • Gefitinib as first-line treatment for patients with advanced non-smallcell lung cancer with activating Epidermal Growth Factor Receptor mutation: implications for clinical practice and open issues
    • Gridelli C, De Marinis F, Di Maio M, et al. Gefitinib as first-line treatment for patients with advanced non-smallcell lung cancer with activating Epidermal Growth Factor Receptor mutation: implications for clinical practice and open issues. Lung Cancer 2011;72:3-8.
    • (2011) Lung Cancer , vol.72 , pp. 3-8
    • Gridelli, C.1    De Marinis, F.2    Di Maio, M.3
  • 12
    • 52049096854 scopus 로고    scopus 로고
    • Gefitinib versus vinorelbine in chemotherapy-naive elderly patients with advanced non-small-cell lung cancer (INVITE): a randomized, phase II study
    • Crinò L, Cappuzzo F, Zatloukal P, et al. Gefitinib versus vinorelbine in chemotherapy-naive elderly patients with advanced non-small-cell lung cancer (INVITE): a randomized, phase II study. J Clin Oncol 2008;26:4253-60.
    • (2008) J Clin Oncol , vol.26 , pp. 4253-4260
    • Crinò, L.1    Cappuzzo, F.2    Zatloukal, P.3
  • 13
    • 77957941643 scopus 로고    scopus 로고
    • First-line gefitinib therapy for elder advanced non-small cell lung cancer patients with epidermal growth factor receptor mutations: Multicenter phase II trial (NEJ 003 study)
    • Minegishi Y, Maemondo M, Okinaga S, et al. First-line gefitinib therapy for elder advanced non-small cell lung cancer patients with epidermal growth factor receptor mutations: Multicenter phase II trial (NEJ 003 study). J Clin Oncol 2010;28:abstr 7561.
    • (2010) J Clin Oncol , vol.28
    • Minegishi, Y.1    Maemondo, M.2    Okinaga, S.3
  • 14
    • 84883558800 scopus 로고    scopus 로고
    • First-line gefitinib for elderly patients harboring EGFR mutations
    • Asami K, Koizumi T, Amejima S, et al. First-line gefitinib for elderly patients harboring EGFR mutations. J Clin Oncol 2010;28:abstr e18094.
    • (2010) J Clin Oncol , vol.28
    • Asami, K.1    Koizumi, T.2    Amejima, S.3
  • 15
    • 75749100264 scopus 로고    scopus 로고
    • Efficacy of gefitinib for elderly patients with advanced non-small cell lung cancer harboring epidermal growth factor receptor gene mutations: a retrospective analysis
    • Uruga H, Kishi K, Fujii T, et al. Efficacy of gefitinib for elderly patients with advanced non-small cell lung cancer harboring epidermal growth factor receptor gene mutations: a retrospective analysis. Intern Med 2010;49:103-7.
    • (2010) Intern Med , vol.49 , pp. 103-107
    • Uruga, H.1    Kishi, K.2    Fujii, T.3
  • 16
    • 65549154268 scopus 로고    scopus 로고
    • Randomized phase II study of gefitinib compared with placebo in chemotherapy-naive patients with advanced non-smallcell lung cancer and poor performance status
    • Goss G, Ferry D, Wierzbicki R, et al. Randomized phase II study of gefitinib compared with placebo in chemotherapy-naive patients with advanced non-smallcell lung cancer and poor performance status. J Clin Oncol 2009;27:2253-60.
    • (2009) J Clin Oncol , vol.27 , pp. 2253-2260
    • Goss, G.1    Ferry, D.2    Wierzbicki, R.3
  • 17
    • 76149135376 scopus 로고    scopus 로고
    • Octogenarians with advanced non-small cell lung cancer: treatment modalities, survival, and prognostic factors
    • Chen KY, Chen JH, Shih JY, et al. Octogenarians with advanced non-small cell lung cancer: treatment modalities, survival, and prognostic factors. J Thorac Oncol 2010;5:82-9.
    • (2010) J Thorac Oncol , vol.5 , pp. 82-89
    • Chen, K.Y.1    Chen, J.H.2    Shih, J.Y.3
  • 18
    • 58949088423 scopus 로고    scopus 로고
    • A phase II trial of gefitinib monotherapy in chemotherapy-naive patients of 75 years or older with advanced non-small cell lung cancer
    • Ebi N, Semba H, Tokunaga SJ, et al. A phase II trial of gefitinib monotherapy in chemotherapy-naive patients of 75 years or older with advanced non-small cell lung cancer. J Thorac Oncol 2008;3:1166-71.
    • (2008) J Thorac Oncol , vol.3 , pp. 1166-1171
    • Ebi, N.1    Semba, H.2    Tokunaga, S.J.3
  • 19
    • 84865686581 scopus 로고    scopus 로고
    • First-line gefitinib in patients aged 75 or older with advanced nonsmall cell lung cancer harboring epidermal growth factor receptor mutations: NEJ 003 study
    • Maemondo M, Minegishi Y, Inoue A, et al. First-line gefitinib in patients aged 75 or older with advanced nonsmall cell lung cancer harboring epidermal growth factor receptor mutations: NEJ 003 study. J Thorac Oncol 2012;7:1417-22.
    • (2012) J Thorac Oncol , vol.7 , pp. 1417-1422
    • Maemondo, M.1    Minegishi, Y.2    Inoue, A.3
  • 20
    • 77649322365 scopus 로고    scopus 로고
    • Second-line therapy for elderly patients with non-small cell lung cancer who failed previous chemotherapy is as effective as for younger patients
    • Wu CH, Fan WC, Chen YM, et al. Second-line therapy for elderly patients with non-small cell lung cancer who failed previous chemotherapy is as effective as for younger patients. J Thorac Oncol 2010;5:376-79.
    • (2010) J Thorac Oncol , vol.5 , pp. 376-379
    • Wu, C.H.1    Fan, W.C.2    Chen, Y.M.3
  • 21
    • 84861742943 scopus 로고    scopus 로고
    • A multicenter phase II randomized trial of gemcitabine followed by erlotinib at progression, versus the reverse sequence, in vulnerable elderly patients with advanced non small-cell lung cancer selected with a comprehensive geriatric assessment (the GFPC 0505 study)
    • LeCaer H, Greillier L, Corre R, et al. A multicenter phase II randomized trial of gemcitabine followed by erlotinib at progression, versus the reverse sequence, in vulnerable elderly patients with advanced non small-cell lung cancer selected with a comprehensive geriatric assessment (the GFPC 0505 study). Lung Cancer 2012;77:97-103.
    • (2012) Lung Cancer , vol.77 , pp. 97-103
    • LeCaer, H.1    Greillier, L.2    Corre, R.3
  • 22
    • 80053943975 scopus 로고    scopus 로고
    • A multicentre phase II randomised trial of weekly docetaxel/gemcitabine followed by erlotinib on progression, vs the reverse sequence, in elderly patients with advanced non small-cell lung cancer selected with a comprehensive geriatric assessment (the GFPC 0504 study)
    • LeCaer H, Barlesi F, Corre R, et al. A multicentre phase II randomised trial of weekly docetaxel/gemcitabine followed by erlotinib on progression, vs the reverse sequence, in elderly patients with advanced non small-cell lung cancer selected with a comprehensive geriatric assessment (the GFPC 0504 study). Br J Cancer 2011;105:1123-30.
    • (2011) Br J Cancer , vol.105 , pp. 1123-1130
    • LeCaer, H.1    Barlesi, F.2    Corre, R.3
  • 23
    • 37849052774 scopus 로고    scopus 로고
    • Outcomes for elderly, advanced-stage non small-cell lung cancer patients treated with bevacizumab in combination with carboplatin and paclitaxel: analysis of Eastern Cooperative Oncology Group Trial 4599
    • Ramalingam SS, Dahlberg SE, Langer CJ, et al. Outcomes for elderly, advanced-stage non small-cell lung cancer patients treated with bevacizumab in combination with carboplatin and paclitaxel: analysis of Eastern Cooperative Oncology Group Trial 4599. J Clin Oncol 2008;26:60-5.
    • (2008) J Clin Oncol , vol.26 , pp. 60-65
    • Ramalingam, S.S.1    Dahlberg, S.E.2    Langer, C.J.3
  • 24
    • 62449124416 scopus 로고    scopus 로고
    • Phase III trial of cisplatin plus gemcitabine with either placebo or bevacizumab as first-line therapy for nonsquamous non-small-cell lung cancer: AVAil
    • Reck M, von Pawel J, Zatloukal P, et al. Phase III trial of cisplatin plus gemcitabine with either placebo or bevacizumab as first-line therapy for nonsquamous non-small-cell lung cancer: AVAil. J Clin Oncol 2009;27:1227-34.
    • (2009) J Clin Oncol , vol.27 , pp. 1227-1234
    • Reck, M.1    von Pawel, J.2    Zatloukal, P.3
  • 25
    • 79960183862 scopus 로고    scopus 로고
    • Clinical outcomes (CO) for special populations of patients (pts) with advanced non-small cell lung cancer (NSCLC): results from ARIES, a bevacizumab (BV) observational cohort study (OCS)
    • Wozniak AJ, Garst J, Jahanzeb M, et al. Clinical outcomes (CO) for special populations of patients (pts) with advanced non-small cell lung cancer (NSCLC): results from ARIES, a bevacizumab (BV) observational cohort study (OCS). J Clin Oncol 2012;28:abstr 7618.
    • (2012) J Clin Oncol , vol.28
    • Wozniak, A.J.1    Garst, J.2    Jahanzeb, M.3
  • 26
    • 84867902025 scopus 로고    scopus 로고
    • Clinical outcomes and biomarker profiles of elderly pretreated NSCLC patients from the BATTLE trial
    • Tsao AS, Liu S, Lee JJ, et al. Clinical outcomes and biomarker profiles of elderly pretreated NSCLC patients from the BATTLE trial. J Thorac Oncol 2012;7:1645-52.
    • (2012) J Thorac Oncol , vol.7 , pp. 1645-1652
    • Tsao, A.S.1    Liu, S.2    Lee, J.J.3
  • 27
    • 33847064257 scopus 로고    scopus 로고
    • Age-related genetic abnormalities: the Achilles' heel for customizing therapy in elderly lung cancer patients
    • Rosell R, Santarpia M, Moran T, et al. Age-related genetic abnormalities: the Achilles' heel for customizing therapy in elderly lung cancer patients. Personal Med 2007;4:59-72.
    • (2007) Personal Med , vol.4 , pp. 59-72
    • Rosell, R.1    Santarpia, M.2    Moran, T.3
  • 28
    • 35348856117 scopus 로고    scopus 로고
    • Pharmacogenomics comes of age in selecting patients for lung cancer treatment. American Society of Clinical Oncology, 42nd
    • Rosell R. Pharmacogenomics comes of age in selecting patients for lung cancer treatment. American Society of Clinical Oncology, 42nd. Annual Meeting, Educational Book, 2006:425-30.
    • (2006) Annual Meeting, Educational Book , pp. 425-430
    • Rosell, R.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.