Measuring Transcription Rate Changes via Time-Course 4-Thiouridine Pulse-Labelling Improves Transcriptional Target Identification

Journal of Molecular Biology

Volumn 427, Issue 21, 2015, Pages 3368-3374

  Schwarzl, Thomas ^a   Higgins, Desmond G ^a   Kolch, Walter ^a   Duffy, David J ^a  

^a UNIVERSITY COLLEGE DUBLIN   (Ireland)

Author keywords

4sU seq; metabolic labelling; sequencing; systems biology; transcription factor targets

Indexed keywords

4 THIOURIDINE; CYCLIN D; MESSENGER RNA; THIOURIDINE; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; MYCN PROTEIN, HUMAN; NUCLEAR PROTEIN; ONCOPROTEIN; RNA;

ARTICLE; CHROMATIN IMMUNOPRECIPITATION; DNA BASE COMPOSITION; FEEDBACK SYSTEM; GENE IDENTIFICATION; GENE TARGETING; GENETIC TRANSCRIPTION; HUMAN; MULTIDIMENSIONAL SCALING; ONCOGENE C MYC; PRIORITY JOURNAL; PROTEIN EXPRESSION; RNA ANALYSIS; RNA EXTRACTION; RNA SEQUENCE; TRANSCRIPTION INITIATION SITE; BINDING SITE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; NEUROBLASTOMA; NUCLEOTIDE SEQUENCE; PROCEDURES; SEQUENCE ANALYSIS; SYSTEMS BIOLOGY; TUMOR CELL LINE;

BASE SEQUENCE; BINDING SITES; CELL LINE, TUMOR; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; HUMANS; NEUROBLASTOMA; NUCLEAR PROTEINS; ONCOGENE PROTEINS; RNA; SEQUENCE ANALYSIS, RNA; SYSTEMS BIOLOGY; THIOURIDINE; TRANSCRIPTION FACTORS;

EID: 84944278562     PISSN: 00222836     EISSN: 10898638     Source Type: Journal    
DOI: 10.1016/j.jmb.2015.09.006     Document Type: Article

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