메뉴 건너뛰기




Volumn 120, Issue 5, 2015, Pages e191-e198

Aggressive giant cell lesion of the jaws: a review of management options and report of a mandibular lesion treated with denosumab

Author keywords

[No Author keywords available]

Indexed keywords

BONE DENSITY CONSERVATION AGENT; CALCIUM; DENOSUMAB; GLUCOCORTICOID; TRIAMCINOLONE; VITAMIN D;

EID: 84944177801     PISSN: 22124403     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.oooo.2015.07.011     Document Type: Article
Times cited : (22)

References (71)
  • 1
    • 50449136862 scopus 로고
    • Giant-cell reparative granuloma, traumatic bone cyst, and fibrous (fibro-osseous) dysplasia of the jaw bones
    • H.L. Jaffe Giant-cell reparative granuloma, traumatic bone cyst, and fibrous (fibro-osseous) dysplasia of the jaw bones Oral Surg 6 1953 159 175
    • (1953) Oral Surg , vol.6 , pp. 159-175
    • Jaffe, H.L.1
  • 2
    • 0024060648 scopus 로고
    • A clinical and histomorphologic comparison of the central giant cell granuloma and the giant cell tumour
    • P.L. Auclair, P. Cuenin, F.J. Kratochyil, L.J. Slater, and G.L. Ellis A clinical and histomorphologic comparison of the central giant cell granuloma and the giant cell tumour Oral Surg Oral Med Oral Pathol 66 1988 197 208
    • (1988) Oral Surg Oral Med Oral Pathol , vol.66 , pp. 197-208
    • Auclair, P.L.1    Cuenin, P.2    Kratochyil, F.J.3    Slater, L.J.4    Ellis, G.L.5
  • 4
    • 0001492621 scopus 로고
    • Giant cell reparative granuloma and related conditions affecting the jawbones
    • L.T. Austin, C.D. Dahlin, and Q.R. Royer Giant cell reparative granuloma and related conditions affecting the jawbones Oral Surg Oral Med Oral Pathol 12 1959 1285 1295
    • (1959) Oral Surg Oral Med Oral Pathol , vol.12 , pp. 1285-1295
    • Austin, L.T.1    Dahlin, C.D.2    Royer, Q.R.3
  • 5
    • 0023958388 scopus 로고
    • Radiologic features, including those seen with computed tomography, of central giant cell granuloma of the jaws
    • M. Cohen, and Y. Hertzanu Radiologic features, including those seen with computed tomography, of central giant cell granuloma of the jaws Oral Surg Oral Med Oral Pathol 65 1988 255
    • (1988) Oral Surg Oral Med Oral Pathol , vol.65 , pp. 255
    • Cohen, M.1    Hertzanu, Y.2
  • 7
    • 4344645084 scopus 로고    scopus 로고
    • Incidence and disease free survival after surgical therapy of central giant cell granulomas of the jaws in The Netherlands; 1990-1995
    • J. de Lange, H.P. van den Akker, and H. Klip Incidence and disease free survival after surgical therapy of central giant cell granulomas of the jaws in The Netherlands; 1990-1995 Head Neck 26 2004 792 795
    • (2004) Head Neck , vol.26 , pp. 792-795
    • De Lange, J.1    Van Den Akker, H.P.2    Klip, H.3
  • 9
    • 0025821019 scopus 로고
    • Noonan-like/multiple giant cell lesion syndrome
    • M.M. Cohen Jr., and R.J. Gorlin Noonan-like/multiple giant cell lesion syndrome Am J Med Genet 40 1991 159
    • (1991) Am J Med Genet , vol.40 , pp. 159
    • Cohen, M.M.1    Gorlin, R.J.2
  • 10
    • 0027406902 scopus 로고
    • Multiple peripheral odontogenic fibroma, World Health Organaization type, and giant cell granuloma: a report of an unusual association
    • G. Ficarra, P. Sapp, and L.R. Eversole Multiple peripheral odontogenic fibroma, World Health Organaization type, and giant cell granuloma: a report of an unusual association J Oral Maxillofac Surg 51 1993 325 328
    • (1993) J Oral Maxillofac Surg , vol.51 , pp. 325-328
    • Ficarra, G.1    Sapp, P.2    Eversole, L.R.3
  • 11
    • 0027406902 scopus 로고
    • Multiple peripheral odontogenic fibroma, World Health Organization type, and giant cell granuloma: a report of an unusual association
    • G. Ficarra, P. Sapp, and L.R. Eversole Multiple peripheral odontogenic fibroma, World Health Organization type, and giant cell granuloma: a report of an unusual association J Oral Maxillofac Surg 51 1993 325 328
    • (1993) J Oral Maxillofac Surg , vol.51 , pp. 325-328
    • Ficarra, G.1    Sapp, P.2    Eversole, L.R.3
  • 12
    • 0032969125 scopus 로고    scopus 로고
    • Bilateral central giant cell granulomas in a patient with neurofibromatosis: report of a case and review of the literature
    • L. Ardekian, R. Manor, M. Peled, and D. Laufer Bilateral central giant cell granulomas in a patient with neurofibromatosis: report of a case and review of the literature J Oral Maxillofac Surg 57 1999 869 872
    • (1999) J Oral Maxillofac Surg , vol.57 , pp. 869-872
    • Ardekian, L.1    Manor, R.2    Peled, M.3    Laufer, D.4
  • 14
    • 0034977079 scopus 로고    scopus 로고
    • Mutations in the gene encoding c-Abl-binding protein SH3 BP2 causes cherubism
    • Y. Ueki, V. Tiziani, C. Santanna, and et al. Mutations in the gene encoding c-Abl-binding protein SH3 BP2 causes cherubism Nat Genet 28 2001 125 126
    • (2001) Nat Genet , vol.28 , pp. 125-126
    • Ueki, Y.1    Tiziani, V.2    Santanna, C.3
  • 15
    • 2642651900 scopus 로고    scopus 로고
    • Noonan syndrome associated with central giant cell granuloma
    • B. Ucar, A. Okten, H. Mocan, and C. Ercin Noonan syndrome associated with central giant cell granuloma Clin Genet 53 1998 411 414
    • (1998) Clin Genet , vol.53 , pp. 411-414
    • Ucar, B.1    Okten, A.2    Mocan, H.3    Ercin, C.4
  • 17
    • 13344270276 scopus 로고    scopus 로고
    • Cherubism-new hypothesis on pathogenesis and therapeutic consequences
    • P. Hyckel, A. Berndt, P. Schleier, and et al. Cherubism-new hypothesis on pathogenesis and therapeutic consequences J Craniomaxillofac Surg 33 2005 61 68
    • (2005) J Craniomaxillofac Surg , vol.33 , pp. 61-68
    • Hyckel, P.1    Berndt, A.2    Schleier, P.3
  • 18
    • 7944227070 scopus 로고    scopus 로고
    • Point mutations of 3 BP2 identified in human inherited disease cherubism result in the loss of function
    • S.M. Miah, T. Hatani, X. Qu, H. Yamamura, and K. Sada Point mutations of 3 BP2 identified in human inherited disease cherubism result in the loss of function Genes Cells 9 2004 993 1004
    • (2004) Genes Cells , vol.9 , pp. 993-1004
    • Miah, S.M.1    Hatani, T.2    Qu, X.3    Yamamura, H.4    Sada, K.5
  • 19
    • 40149085868 scopus 로고    scopus 로고
    • Mutations in SH3 BP2, the cherubism gene, were not detected in central or peripheral giant cell tumors of the jaw
    • B.D. Idowu, G. Thomas, R. Frow, and et al. Mutations in SH3 BP2, the cherubism gene, were not detected in central or peripheral giant cell tumors of the jaw Br J Oral Maxillofac Surg 46 2008 229
    • (2008) Br J Oral Maxillofac Surg , vol.46 , pp. 229
    • Idowu, B.D.1    Thomas, G.2    Frow, R.3
  • 20
    • 0038466065 scopus 로고    scopus 로고
    • Multinucleated giant cells in various forms of giant cell containing lesions of the jaws express features of osteoclasts
    • B. Liu, S.-F. Yu, and T.-J. Li Multinucleated giant cells in various forms of giant cell containing lesions of the jaws express features of osteoclasts J Oral Pathol Med 32 2003 367
    • (2003) J Oral Pathol Med , vol.32 , pp. 367
    • Liu, B.1    Yu, S.-F.2    Li, T.-J.3
  • 21
    • 33745191197 scopus 로고    scopus 로고
    • Immunohistochemical expression of glucocorticoid and calcitonin receptors as a tool for selecting therapeutic approach in central giant cell granuloma of the jaw bones
    • M. Vered, A. Buchner, and D. Dayan Immunohistochemical expression of glucocorticoid and calcitonin receptors as a tool for selecting therapeutic approach in central giant cell granuloma of the jaw bones Int J Oral Maxillofac Surg 35 2006 756 760
    • (2006) Int J Oral Maxillofac Surg , vol.35 , pp. 756-760
    • Vered, M.1    Buchner, A.2    Dayan, D.3
  • 22
    • 0030983835 scopus 로고    scopus 로고
    • Markers for macrophage and osteoclast lineages in giant cell lesions of the oral cavity
    • J.C. Tiffee, and T.B. Aufdemorte Markers for macrophage and osteoclast lineages in giant cell lesions of the oral cavity J Oral Maxillofac Surg 55 1997 1108 1112
    • (1997) J Oral Maxillofac Surg , vol.55 , pp. 1108-1112
    • Tiffee, J.C.1    Aufdemorte, T.B.2
  • 23
    • 0037947843 scopus 로고    scopus 로고
    • Cellular mechanisms of osteoclast formation and lacunar resorption in giant cell granuloma of the jaw
    • I. Itonaga, I. Hussein, O. Kudo, and et al. Cellular mechanisms of osteoclast formation and lacunar resorption in giant cell granuloma of the jaw J Oral Pathol Med 32 2003 224 231
    • (2003) J Oral Pathol Med , vol.32 , pp. 224-231
    • Itonaga, I.1    Hussein, I.2    Kudo, O.3
  • 24
    • 33749515101 scopus 로고    scopus 로고
    • Giant cell granuloma of the jaw bones - a proliferative vascular lesion? Immunohistochemical study with vascular endothelial growth factor and basic fibroblast growth factor
    • M. Vered, A. Buchner, and D. Dayan Giant cell granuloma of the jaw bones - a proliferative vascular lesion? Immunohistochemical study with vascular endothelial growth factor and basic fibroblast growth factor J Oral Pathol Med 53 2006 613 619
    • (2006) J Oral Pathol Med , vol.53 , pp. 613-619
    • Vered, M.1    Buchner, A.2    Dayan, D.3
  • 25
    • 29844432457 scopus 로고    scopus 로고
    • Long-term clinical and radiological outcomes of surgical management of central giant cell granuloma of the maxilla
    • M. Rawashdeh, A. Bataineh, and T. Al-Khateeb Long-term clinical and radiological outcomes of surgical management of central giant cell granuloma of the maxilla Int J Oral Maxillofac Surg 35 2006 60 66
    • (2006) Int J Oral Maxillofac Surg , vol.35 , pp. 60-66
    • Rawashdeh, M.1    Bataineh, A.2    Al-Khateeb, T.3
  • 28
    • 0024501785 scopus 로고
    • Central giant cell granulomas of the jaws: nuclear DNA analysis using image cytometry
    • A. Eckardt, M.A. Pogrel, L.B. Kaban, and et al. Central giant cell granulomas of the jaws: nuclear DNA analysis using image cytometry Int J Oral Maxillofac Surg 18 1989 3
    • (1989) Int J Oral Maxillofac Surg , vol.18 , pp. 3
    • Eckardt, A.1    Pogrel, M.A.2    Kaban, L.B.3
  • 29
    • 0023368544 scopus 로고
    • Central giant cell lesions of the mandible and maxilla: a clinicopathologic and cytometric study
    • G. Ficarra, L.B. Kaban, and L.S. Hansen Central giant cell lesions of the mandible and maxilla: a clinicopathologic and cytometric study Oral Surg Oral Med Oral Pathol 64 1987 44
    • (1987) Oral Surg Oral Med Oral Pathol , vol.64 , pp. 44
    • Ficarra, G.1    Kaban, L.B.2    Hansen, L.S.3
  • 30
    • 0031128203 scopus 로고    scopus 로고
    • Central giant cell granulomas of the jaws: phenotype and proliferation-associated markers
    • M. O'Malley, M.A. Pogrel, J.C. Stewart, and et al. Central giant cell granulomas of the jaws: phenotype and proliferation-associated markers J Oral Pathol Med 26 1997 159
    • (1997) J Oral Pathol Med , vol.26 , pp. 159
    • O'Malley, M.1    Pogrel, M.A.2    Stewart, J.C.3
  • 31
    • 42149174911 scopus 로고    scopus 로고
    • Immunohistochemical evaluation of giant cell tumors of the jaws using CD34 density analysis
    • N.C. Dewsnup, S.M. Susarla, M. Abulikemu, and et al. Immunohistochemical evaluation of giant cell tumors of the jaws using CD34 density analysis J Oral Maxillofac Surg 66 2008 928
    • (2008) J Oral Maxillofac Surg , vol.66 , pp. 928
    • Dewsnup, N.C.1    Susarla, S.M.2    Abulikemu, M.3
  • 32
    • 0022858879 scopus 로고
    • Combined curettage and cryosurgical treatment for the aggressive "giant cell lesion" of the mandible
    • D.J. Webb, and J. Brockbank Combined curettage and cryosurgical treatment for the aggressive "giant cell lesion" of the mandible Int J Oral Maxillofac Surg 5 1986 780
    • (1986) Int J Oral Maxillofac Surg , vol.5 , pp. 780
    • Webb, D.J.1    Brockbank, J.2
  • 33
    • 0023922323 scopus 로고
    • Central giant cell granuloma of the jaws: experiences in the management of thirty-seven cases
    • L. Eisenbud, M. Stern, M. Rothberg, and et al. Central giant cell granuloma of the jaws: experiences in the management of thirty-seven cases J Oral Maxillofac Surg 46 1988 376 384
    • (1988) J Oral Maxillofac Surg , vol.46 , pp. 376-384
    • Eisenbud, L.1    Stern, M.2    Rothberg, M.3
  • 35
    • 34548612363 scopus 로고    scopus 로고
    • Adjuvant antiangiogenic therapy for giant cell tumors of the jaws
    • L.B. Kaban, M.J. Troulis, M.J. Wilkinson, and et al. Adjuvant antiangiogenic therapy for giant cell tumors of the jaws J Oral Maxillofac Surg 65 2007 2018
    • (2007) J Oral Maxillofac Surg , vol.65 , pp. 2018
    • Kaban, L.B.1    Troulis, M.J.2    Wilkinson, M.J.3
  • 36
    • 0029950632 scopus 로고    scopus 로고
    • Prognostic significance of cortical perforation in the recurrence of central giant cell granulomas of the jaws
    • A. Minic, and Z. Stajcic Prognostic significance of cortical perforation in the recurrence of central giant cell granulomas of the jaws J Craniomaxillofac Surg 24 1996 104
    • (1996) J Craniomaxillofac Surg , vol.24 , pp. 104
    • Minic, A.1    Stajcic, Z.2
  • 37
    • 0036295474 scopus 로고    scopus 로고
    • The surgical treatment of central giant cell granuloma of the mandible
    • A. Bataineh, T. Al-Khateeb, and M. Rawashdeh The surgical treatment of central giant cell granuloma of the mandible J Oral Maxillofac Surg 60 2002 756 761
    • (2002) J Oral Maxillofac Surg , vol.60 , pp. 756-761
    • Bataineh, A.1    Al-Khateeb, T.2    Rawashdeh, M.3
  • 38
    • 0023765965 scopus 로고
    • The multinucleate cells in the giant cell granulomas of the jaw are osteoclasts
    • A.M. Flanagan, B. Nui, S.M.B. Tinkler, and et al. The multinucleate cells in the giant cell granulomas of the jaw are osteoclasts Cancer 62 1988 1139
    • (1988) Cancer , vol.62 , pp. 1139
    • Flanagan, A.M.1    Nui, B.2    Tinkler, S.M.B.3
  • 39
    • 0022448217 scopus 로고
    • Dexamethasone inhibits formation of osteoclast-like cells in bone-marrow cultures
    • M.J. Pharoah, and J.N.M. Heersche Dexamethasone inhibits formation of osteoclast-like cells in bone-marrow cultures J Dent Res 65 1986 1006
    • (1986) J Dent Res , vol.65 , pp. 1006
    • Pharoah, M.J.1    Heersche, J.N.M.2
  • 40
    • 0000327480 scopus 로고
    • Central giant cell granuloma - an alternative to surgical therapy [abstract]
    • J.R. Jacoway, F.V. Howell, and B.C. Terry Central giant cell granuloma - an alternative to surgical therapy [abstract] Oral Surg Oral Med Oral Pathol 66 1988 572
    • (1988) Oral Surg Oral Med Oral Pathol , vol.66 , pp. 572
    • Jacoway, J.R.1    Howell, F.V.2    Terry, B.C.3
  • 41
    • 0028708485 scopus 로고
    • Local injection of corticosteroids for central giant cell granuloma. A case report
    • C. Kermer, W. Millesi, and I.M. Watzke Local injection of corticosteroids for central giant cell granuloma. A case report Int J Oral Maxillofac Surg 23 1994 366 368
    • (1994) Int J Oral Maxillofac Surg , vol.23 , pp. 366-368
    • Kermer, C.1    Millesi, W.2    Watzke, I.M.3
  • 43
    • 0032135568 scopus 로고    scopus 로고
    • Intralesional corticosteroid injection for central giant cell granuloma: a case report
    • N.S. Rajeevan, and C.S. Soumithran Intralesional corticosteroid injection for central giant cell granuloma: a case report Int J Oral Maxillofac Surg 27 1998 303
    • (1998) Int J Oral Maxillofac Surg , vol.27 , pp. 303
    • Rajeevan, N.S.1    Soumithran, C.S.2
  • 44
    • 33745713830 scopus 로고    scopus 로고
    • Oral and intralesional steroid therapy in giant cell granuloma
    • E. Comert, M. Turanli, and S. Ulu Oral and intralesional steroid therapy in giant cell granuloma Acta Otolaryngol 26 2006 664
    • (2006) Acta Otolaryngol , vol.26 , pp. 664
    • Comert, E.1    Turanli, M.2    Ulu, S.3
  • 46
    • 0030805263 scopus 로고    scopus 로고
    • Glucocorticoids inhibit bone resorption in isolated rat osteoclasts by inducing apoptosis
    • O.W. Dempster, B.S. Moonga, L.S. Stein, W.R. Horbert, and T. Antakly Glucocorticoids inhibit bone resorption in isolated rat osteoclasts by inducing apoptosis J Endocrinol 154 1997 397 406
    • (1997) J Endocrinol , vol.154 , pp. 397-406
    • Dempster, O.W.1    Moonga, B.S.2    Stein, L.S.3    Horbert, W.R.4    Antakly, T.5
  • 47
    • 0027467447 scopus 로고
    • Central giant cell granulomas of the jaws regress with calcitonin therapy
    • M. Harris Central giant cell granulomas of the jaws regress with calcitonin therapy Br J Oral Maxillofac Surg 31 1993 89
    • (1993) Br J Oral Maxillofac Surg , vol.31 , pp. 89
    • Harris, M.1
  • 48
    • 0037849857 scopus 로고    scopus 로고
    • Calcitonin therapy for central giant cell granuloma
    • M.A. Pogrel Calcitonin therapy for central giant cell granuloma J Oral Maxillofac Surg 61 2003 649 653
    • (2003) J Oral Maxillofac Surg , vol.61 , pp. 649-653
    • Pogrel, M.A.1
  • 51
    • 0033041691 scopus 로고    scopus 로고
    • Calcitonin treatment for central giant cell granulomas of the mandible: report of two cases
    • M.A. Pogrel, J.A. Regezi, S.T. Harris, and et al. Calcitonin treatment for central giant cell granulomas of the mandible: report of two cases J Oral Maxillofac Surg 57 1999 848
    • (1999) J Oral Maxillofac Surg , vol.57 , pp. 848
    • Pogrel, M.A.1    Regezi, J.A.2    Harris, S.T.3
  • 52
    • 33746033782 scopus 로고    scopus 로고
    • Limited regression of central giant cell granuloma by interferon alpha after failed calcitonin therapy: a report of 2 cases
    • J. de Lange, H.P. van der Akker, H. van der Berg, D.J. Richel, and R.A. Gortzak Limited regression of central giant cell granuloma by interferon alpha after failed calcitonin therapy: a report of 2 cases Int J Oral Maxillofac Surg 35 2006 865 869
    • (2006) Int J Oral Maxillofac Surg , vol.35 , pp. 865-869
    • De Lange, J.1    Van Der Akker, H.P.2    Van Der Berg, H.3    Richel, D.J.4    Gortzak, R.A.5
  • 53
    • 0033041884 scopus 로고    scopus 로고
    • Antiangiogenic therapy of a recurrent giant cell tumour of the mandible with interferon alpha-2 a
    • K.B. Kaban, J.B. Mulliken, R.A. Ezekowitz, D. Ebb, P.S. Smith, and J. Folkman Antiangiogenic therapy of a recurrent giant cell tumour of the mandible with interferon alpha-2 a Paediatrics 103 1999 11145 11149
    • (1999) Paediatrics , vol.103 , pp. 11145-11149
    • Kaban, K.B.1    Mulliken, J.B.2    Ezekowitz, R.A.3    Ebb, D.4    Smith, P.S.5    Folkman, J.6
  • 56
    • 0019306152 scopus 로고
    • Inhibition of cell motility by interferon
    • D. Brouty-Boye, and B. Zetter Inhibition of cell motility by interferon Science 208 1980 516
    • (1980) Science , vol.208 , pp. 516
    • Brouty-Boye, D.1    Zetter, B.2
  • 57
    • 0023160237 scopus 로고
    • Inhibition of angiogenesis by interferons: effects on tumour- and lymphocyte-induced vascular responses
    • Y.A. Sidky, and E.C. Borden Inhibition of angiogenesis by interferons: effects on tumour- and lymphocyte-induced vascular responses Cancer Res 47 1987 5155
    • (1987) Cancer Res , vol.47 , pp. 5155
    • Sidky, Y.A.1    Borden, E.C.2
  • 58
    • 0024517730 scopus 로고
    • Treatment of pulmonary haemangiomatosis with recombinant interferon alpha-2 a
    • C.W. White, H.M. Sondheimer, E.C. Crouch, and et al. Treatment of pulmonary haemangiomatosis with recombinant interferon alpha-2 a N Engl J Med 320 1989 1197
    • (1989) N Engl J Med , vol.320 , pp. 1197
    • White, C.W.1    Sondheimer, H.M.2    Crouch, E.C.3
  • 59
    • 84878345657 scopus 로고    scopus 로고
    • Aggressive giant cell granuloma of the jaws treated with interferon alpha: a report of two cases
    • J.E. O'Connell, and G.J. Kearns Aggressive giant cell granuloma of the jaws treated with interferon alpha: a report of two cases Ir J Med Sci 182 2013 163 170
    • (2013) Ir J Med Sci , vol.182 , pp. 163-170
    • O'Connell, J.E.1    Kearns, G.J.2
  • 60
    • 84880770534 scopus 로고    scopus 로고
    • Safety and efficacy of denosumab for adults and skeletally mature adolescents with giant cell tumour of bone: interim analysis of an open-label, parallel-group, phase 2 study
    • S. Chawla, R. Henshaw, L. Seeger, and et al. Safety and efficacy of denosumab for adults and skeletally mature adolescents with giant cell tumour of bone: interim analysis of an open-label, parallel-group, phase 2 study Lancet Oncol 14 2013 901 908
    • (2013) Lancet Oncol , vol.14 , pp. 901-908
    • Chawla, S.1    Henshaw, R.2    Seeger, L.3
  • 61
    • 79952614068 scopus 로고    scopus 로고
    • The role of RANK-ligand inhibition in cancer: the story of denosumab
    • D. Castellano, J.M. Sepulveda, I. GarcIa-Escobar, and et al. The role of RANK-ligand inhibition in cancer: the story of denosumab Oncologist 16 2011 136
    • (2011) Oncologist , vol.16 , pp. 136
    • Castellano, D.1    Sepulveda, J.M.2    Garcia-Escobar, I.3
  • 62
    • 84862809842 scopus 로고    scopus 로고
    • Denosumab in patients with cancer - a surgical strike against the osteoclast
    • J.E. Brown, and R.E. Coleman Denosumab in patients with cancer - a surgical strike against the osteoclast Nat Rev Clin Oncol 9 2012 110
    • (2012) Nat Rev Clin Oncol , vol.9 , pp. 110
    • Brown, J.E.1    Coleman, R.E.2
  • 63
    • 77349120482 scopus 로고    scopus 로고
    • Denosumab in patients with giant-cell tumour of bone: an open-label, phase 2 study
    • D. Thomas, R. Henshaw, K. Skubitz, and et al. Denosumab in patients with giant-cell tumour of bone: an open-label, phase 2 study Lancet Oncol 11 2010 275
    • (2010) Lancet Oncol , vol.11 , pp. 275
    • Thomas, D.1    Henshaw, R.2    Skubitz, K.3
  • 64
    • 84922876343 scopus 로고    scopus 로고
    • Management of central giant cell granuloma with subcutaneous denosumab therapy
    • A. Naidu, M.P. Malmquist, C.A. Denham, and S.R. Schow Management of central giant cell granuloma with subcutaneous denosumab therapy J Oral Maxillofac Surg 72 2014 2469 2484
    • (2014) J Oral Maxillofac Surg , vol.72 , pp. 2469-2484
    • Naidu, A.1    Malmquist, M.P.2    Denham, C.A.3    Schow, S.R.4
  • 65
    • 84902958919 scopus 로고    scopus 로고
    • Alternative pharmacologic therapy for aggressive central giant cell granuloma: denosumab
    • W.H. Schreuder, A.W. Coumou, P.A. Kessler, and J. de Lange Alternative pharmacologic therapy for aggressive central giant cell granuloma: denosumab J Oral Maxillofac Surg 72 2014 1301 1309
    • (2014) J Oral Maxillofac Surg , vol.72 , pp. 1301-1309
    • Schreuder, W.H.1    Coumou, A.W.2    Kessler, P.A.3    De Lange, J.4
  • 66
    • 3342982829 scopus 로고    scopus 로고
    • A single-dose placebo-controlled study of AMG 162, a fully human monoclonal antibody to RANKL, in postmenopausal women
    • P.J. Bekker, D.L. Holloway, A.S. Rasmussen, and et al. A single-dose placebo-controlled study of AMG 162, a fully human monoclonal antibody to RANKL, in postmenopausal women J Bone Miner Res 19 2004 1059 1066
    • (2004) J Bone Miner Res , vol.19 , pp. 1059-1066
    • Bekker, P.J.1    Holloway, D.L.2    Rasmussen, A.S.3
  • 67
    • 79551568488 scopus 로고    scopus 로고
    • Denosumab compared with zoledronic acid for the treatment of bone metastases in patients with advanced breast cancer: a randomized, double-blind study
    • A.T. Stopeck, A. Lipton, J.J. Body, and et al. Denosumab compared with zoledronic acid for the treatment of bone metastases in patients with advanced breast cancer: a randomized, double-blind study J Clin Oncol 28 2010 5132
    • (2010) J Clin Oncol , vol.28 , pp. 5132
    • Stopeck, A.T.1    Lipton, A.2    Body, J.J.3
  • 68
    • 79952360832 scopus 로고    scopus 로고
    • Denosumab versus zoledronic acid for treatment of bone metastases in men with castration resistant prostate cancer: a randomised, double-blind study
    • K. Fizazi, M. Carducci, M. Smith, and et al. Denosumab versus zoledronic acid for treatment of bone metastases in men with castration resistant prostate cancer: a randomised, double-blind study Lancet 377 2011 813
    • (2011) Lancet , vol.377 , pp. 813
    • Fizazi, K.1    Carducci, M.2    Smith, M.3
  • 69
    • 84944164325 scopus 로고    scopus 로고
    • Update. Accessed January 15, 2015
    • American Association of Oral and Maxillofacial Surgeons: Medication-related osteonecrosis of the jaw - 2014 Update. Available at: Http://www.aaoms.org/docs/position-papers/mronj-position-paper.pdf?pdf=MRONJ-Position-Paper. Accessed January 15, 2015.
    • Medication-related osteonecrosis of the jaw - 2014
  • 70
    • 84863116813 scopus 로고    scopus 로고
    • Five years of denosumab exposure in women with postmenopausal osteoporosis: results from the first two years of the FREEDOM extension
    • S. Papapoulos, R. Chapurlat, C. Libanati, and et al. Five years of denosumab exposure in women with postmenopausal osteoporosis: results from the first two years of the FREEDOM extension J Bone Miner Res 27 2012 694
    • (2012) J Bone Miner Res , vol.27 , pp. 694
    • Papapoulos, S.1    Chapurlat, R.2    Libanati, C.3
  • 71
    • 0038466065 scopus 로고    scopus 로고
    • Multinucleated giant cells in various forms of giant cell containing lesions of the jaws express features of osteoclasts
    • B. Lui, S.F. Yu, and T.J. Li Multinucleated giant cells in various forms of giant cell containing lesions of the jaws express features of osteoclasts J Oral Pathol Med 32 2003 367
    • (2003) J Oral Pathol Med , vol.32 , pp. 367
    • Lui, B.1    Yu, S.F.2    Li, T.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.