IDH1R132H mutation causes a less aggressive phenotype and radiosensitizes human malignant glioma cells independent of the oxygenation status

Radiotherapy and Oncology

Volumn 116, Issue 3, 2015, Pages 381-387

  Kessler, Jacqueline ^a   Güttler, Antje ^a   Wichmann, Henri ^a   Rot, Swetlana ^a   Kappler, Matthias ^a   Bache, Matthias ^a   Vordermark, Dirk ^a  

^a MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

Author keywords

Glioma; Hypoxia; IDH1; IDH1R132H; Isocitrate dehydrogenase 1; Radiation

Indexed keywords

ISOCITRATE DEHYDROGENASE 1; MUTANT PROTEIN; IDH1 PROTEIN, HUMAN; ISOCITRATE DEHYDROGENASE; RADIOSENSITIZING AGENT;

APOPTOSIS; CANCER CELL CULTURE; CANCER GROWTH; CANCER RADIOTHERAPY; CELL HYPOXIA; CELL MIGRATION; CELL MOTILITY; CELL PROLIFERATION; CELL SURVIVAL; COLONY FORMATION; CONFERENCE PAPER; CONTROLLED STUDY; GENE MUTATION; GENE OVEREXPRESSION; GLIOBLASTOMA; GLIOMA CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; OXYGENATION; PHENOTYPE; PRIORITY JOURNAL; RADIOBIOLOGY; RADIOSENSITIVITY; RADIOSENSITIZATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPHEROID CELL; SURVIVAL RATE; WESTERN BLOTTING; ANOXIA; GENETICS; GLIOMA; MUTATION; PATHOPHYSIOLOGY; PHYSIOLOGY; RADIATION TOLERANCE;

ANOXIA; CELL PROLIFERATION; CELL SURVIVAL; GLIOMA; HUMANS; ISOCITRATE DEHYDROGENASE; MUTATION; PHENOTYPE; RADIATION TOLERANCE; RADIATION-SENSITIZING AGENTS;

EID: 84944172039     PISSN: 01678140     EISSN: 18790887     Source Type: Journal    
DOI: 10.1016/j.radonc.2015.08.007     Document Type: Conference Paper

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