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Volumn 25, Issue 21, 2015, Pages 4945-4949

Development of a novel class of potent and selective FIXa inhibitors

Author keywords

Benzimidazole; FIXa inhibitor; Structure based drug design; TGA

Indexed keywords

APIXABAN; BENZIMIDAZOLE DERIVATIVE; BLOOD CLOTTING FACTOR 9A; PROTEIN INHIBITOR; QUINAZOLINONE DERIVATIVE; AMINE; ENZYME INHIBITOR;

EID: 84944158401     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2015.04.057     Document Type: Article
Times cited : (14)

References (20)
  • 10
    • 1642310340 scopus 로고    scopus 로고
    • Compounds were docked into the Factor IXa crystal structure using GlideSP (Maestro Suites 2010 & 2011; Schrödinger, LLC, New York, NY) and then synthetically prioritized according to their overall Glide scores and predicted log D. For reference, see: T.A. Halgren, R.B. Murphy, R.A. Friesner, H.S. Beard, L.L. Frye, W.T. Pollard, and J.L. Banks J. Med. Chem. 47 2004 1750
    • (2004) J. Med. Chem. , vol.47 , pp. 1750
    • Halgren, T.A.1    Murphy, R.B.2    Friesner, R.A.3    Beard, H.S.4    Frye, L.L.5    Pollard, W.T.6    Banks, J.L.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.