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Volumn 48, Issue 7, 2015, Pages 874-882

DNA methylation in individuals with anorexia nervosa and in matched normal-eater controls: A genome-wide study

Author keywords

anorexia nervosa; body mass index; brain development; DNA methylation; eating disorders; epigenetics

Indexed keywords

ADULT; ANOREXIA NERVOSA; ANXIETY DISORDER; ARTICLE; BINGE EATING DISORDER; BULIMIA; CHROMOSOME NUMBER; CLINICAL ARTICLE; CONTROLLED STUDY; CPG ISLAND; DISEASE ASSOCIATION; DISEASE DURATION; DNA METHYLATION; EPIGENETICS; FEMALE; GENOME ANALYSIS; HUMAN; ONSET AGE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SYNAPTOGENESIS; ADOLESCENT; BLOOD; CASE CONTROL STUDY; GENETICS; GENOME-WIDE ASSOCIATION STUDY; PROCEDURES; YOUNG ADULT;

EID: 84944154075     PISSN: 02763478     EISSN: 1098108X     Source Type: Journal    
DOI: 10.1002/eat.22374     Document Type: Article
Times cited : (54)

References (44)
  • 1
    • 78649906686 scopus 로고    scopus 로고
    • Eating disorders, gene-environment interactions and epigenetics
    • Campbell IC, Mill J, Uher R, Schmidt U,. Eating disorders, gene-environment interactions and epigenetics. Neurosci Biobehav Rev 2011; 35: 784-793.
    • (2011) Neurosci Biobehav Rev , vol.35 , pp. 784-793
    • Campbell, I.C.1    Mill, J.2    Uher, R.3    Schmidt, U.4
  • 2
    • 62649117779 scopus 로고    scopus 로고
    • Academy for eating disorders position paper: Eating disorders are serious mental illnesses
    • Klump KL, Bulik CM, Kaye WH, Treasure J, Tyson E,. Academy for eating disorders position paper: Eating disorders are serious mental illnesses. Int J Eat Disord 2009; 42: 97-103.
    • (2009) Int J Eat Disord , vol.42 , pp. 97-103
    • Klump, K.L.1    Bulik, C.M.2    Kaye, W.H.3    Treasure, J.4    Tyson, E.5
  • 3
    • 84916876786 scopus 로고    scopus 로고
    • The plasticity of development: How knowledge of epigenetics may advance understanding of eating disorders
    • Strober M, Peris T, Steiger H,. The plasticity of development: How knowledge of epigenetics may advance understanding of eating disorders. Int J Eat Disord 2014; 7: 696-704.
    • (2014) Int J Eat Disord , vol.7 , pp. 696-704
    • Strober, M.1    Peris, T.2    Steiger, H.3
  • 4
    • 79957489780 scopus 로고    scopus 로고
    • Gene-environment interaction in anorexia nervosa: Relevance of non-shared environment and the serotonin transporter gene
    • Karwautz AF, Wagner G, Waldherr K, Nader IW, Fernandez-Aranda F, Estivill X, et al., Gene-environment interaction in anorexia nervosa: Relevance of non-shared environment and the serotonin transporter gene. Mol Psychiatry 2011; 16: 590-592.
    • (2011) Mol Psychiatry , vol.16 , pp. 590-592
    • Karwautz, A.F.1    Wagner, G.2    Waldherr, K.3    Nader, I.W.4    Fernandez-Aranda, F.5    Estivill, X.6
  • 5
    • 78650190642 scopus 로고    scopus 로고
    • Food restriction leads to binge eating dependent upon the effect of the brain-derived neurotrophic factor Val66Met polymorphism
    • Akkermann K, Hiio K, Villa I, Harro J,. Food restriction leads to binge eating dependent upon the effect of the brain-derived neurotrophic factor Val66Met polymorphism. Psychiatry Res 2011; 185: 39-43.
    • (2011) Psychiatry Res , vol.185 , pp. 39-43
    • Akkermann, K.1    Hiio, K.2    Villa, I.3    Harro, J.4
  • 7
    • 84455169456 scopus 로고    scopus 로고
    • How does the social environment 'get into the mind'? Epigenetics at the intersection of social and psychiatric epidemiology
    • Toyokawa S, Uddin M, Koenen KC, Galea S,. How does the social environment 'get into the mind'? Epigenetics at the intersection of social and psychiatric epidemiology. Soc Sci Med 2012; 74: 67-74.
    • (2012) Soc Sci Med , vol.74 , pp. 67-74
    • Toyokawa, S.1    Uddin, M.2    Koenen, K.C.3    Galea, S.4
  • 8
    • 33847254942 scopus 로고    scopus 로고
    • Global DNA hypomethylation and DNA hypermethylation of the alpha synuclein promoter in females with anorexia nervosa
    • Frieling H, Gozner A, Romer KD, Lenz B, Bonsch D, Wilhelm J, et al., Global DNA hypomethylation and DNA hypermethylation of the alpha synuclein promoter in females with anorexia nervosa. Mol Psychiatry 2007; 12: 229-230.
    • (2007) Mol Psychiatry , vol.12 , pp. 229-230
    • Frieling, H.1    Gozner, A.2    Romer, K.D.3    Lenz, B.4    Bonsch, D.5    Wilhelm, J.6
  • 9
    • 51749123969 scopus 로고    scopus 로고
    • Epigenetic downregulation of atrial natriuretic peptide but not vasopressin mRNA expression in females with eating disorders is related to impulsivity
    • Frieling H, Bleich S, Otten J, Romer KD, Kornhuber J, de Zwaan M, et al., Epigenetic downregulation of atrial natriuretic peptide but not vasopressin mRNA expression in females with eating disorders is related to impulsivity. Neuropsychopharmacology 2008; 33: 2605-2609.
    • (2008) Neuropsychopharmacology , vol.33 , pp. 2605-2609
    • Frieling, H.1    Bleich, S.2    Otten, J.3    Romer, K.D.4    Kornhuber, J.5    De Zwaan, M.6
  • 10
    • 77956338909 scopus 로고    scopus 로고
    • Promoter specific DNA methylation and gene expression of POMC in acutely underweight and recovered patients with anorexia nervosa
    • Ehrlich S, Weiss D, Burghardt R, Infante-Duarte C, Brockhaus S, Muschler MA, et al., Promoter specific DNA methylation and gene expression of POMC in acutely underweight and recovered patients with anorexia nervosa. J Psychiatr Res 2010; 44: 827-833.
    • (2010) J Psychiatr Res , vol.44 , pp. 827-833
    • Ehrlich, S.1    Weiss, D.2    Burghardt, R.3    Infante-Duarte, C.4    Brockhaus, S.5    Muschler, M.A.6
  • 11
    • 84895755456 scopus 로고    scopus 로고
    • Differential methylation of the oxytocin receptor gene in patients with anorexia nervosa: A pilot study
    • Kim YR, Kim JH, Kim MJ, Treasure J,. Differential methylation of the oxytocin receptor gene in patients with anorexia nervosa: A pilot study. PLoS One 2014; 9: e88673.
    • (2014) PLoS One , vol.9 , pp. e88673
    • Kim, Y.R.1    Kim, J.H.2    Kim, M.J.3    Treasure, J.4
  • 13
    • 84895076452 scopus 로고    scopus 로고
    • Assessing global and gene specific DNA methylation in anorexia nervosa: A pilot study
    • Saffrey R, Novakovic B, Wade TD,. Assessing global and gene specific DNA methylation in anorexia nervosa: A pilot study. Int J Eat Disord 2014; 47: 206-210.
    • (2014) Int J Eat Disord , vol.47 , pp. 206-210
    • Saffrey, R.1    Novakovic, B.2    Wade, T.D.3
  • 14
    • 84900808650 scopus 로고    scopus 로고
    • Decreased whole-blood global DNA methylation is related to serum hormones in anorexia nervosa adolescents
    • Tremolizzo L, Conti E, Bomba M, Uccellini O, Rossi MS, Marfone M, et al., Decreased whole-blood global DNA methylation is related to serum hormones in anorexia nervosa adolescents. World J Biol Psychiatry 2014; 15: 327-333.
    • (2014) World J Biol Psychiatry , vol.15 , pp. 327-333
    • Tremolizzo, L.1    Conti, E.2    Bomba, M.3    Uccellini, O.4    Rossi, M.S.5    Marfone, M.6
  • 15
    • 0003472502 scopus 로고    scopus 로고
    • American Psychiatric Association. 5th ed. Arlington,VA: American Psychiatric Publishing.
    • American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders, 5th ed. Arlington,VA: American Psychiatric Publishing, 2013.
    • (2013) Diagnostic and Statistical Manual of Mental Disorders
  • 16
    • 0001879817 scopus 로고
    • The eating disorders examination
    • Fairburn C.G. Terence Wilson G. editors. New York: Guilford
    • Fairburn CG, Cooper P,. The eating disorders examination. In:, Fairburn CG, Terence Wilson G, editors. Binge Eating: Nature, Assessment, and Treatment. New York: Guilford, 1993, pp. 317-360.
    • (1993) Binge Eating: Nature, Assessment, and Treatment , pp. 317-360
    • Fairburn, C.G.1    Cooper, P.2
  • 17
    • 0033000087 scopus 로고    scopus 로고
    • The reliability of the eating disorder examination-self-report questionnaire version (EDE-Q)
    • Luce KH, Crowther JH,. The reliability of the eating disorder examination-self-report questionnaire version (EDE-Q). Int J Eat Disord 1999; 25: 349-351.
    • (1999) Int J Eat Disord , vol.25 , pp. 349-351
    • Luce, K.H.1    Crowther, J.H.2
  • 19
    • 1642334048 scopus 로고    scopus 로고
    • Validity of the eating disorder examination questionnaire (EDE-Q) in screening for eating disorders in community samples
    • Mond JM, Hay PJ, Rodgers B, Owen C, Beumont PJ,. Validity of the eating disorder examination questionnaire (EDE-Q) in screening for eating disorders in community samples. Behav Res Ther 2004; 42: 551-567.
    • (2004) Behav Res Ther , vol.42 , pp. 551-567
    • Mond, J.M.1    Hay, P.J.2    Rodgers, B.3    Owen, C.4    Beumont, P.J.5
  • 20
    • 84965520932 scopus 로고
    • The CES-D scale: A self-report depression scale for research in the general population
    • Radloff LS,. The CES-D scale: A self-report depression scale for research in the general population. Appl Psychol Meas 1977; 1: 385-401.
    • (1977) Appl Psychol Meas , vol.1 , pp. 385-401
    • Radloff, L.S.1
  • 21
    • 0029567978 scopus 로고
    • Factor structure of the Barratt impulsiveness scale
    • Patton JH, Stanford MS, Barratt ES,. Factor structure of the Barratt impulsiveness scale. J Clin Psychol 1995; 51: 768-774.
    • (1995) J Clin Psychol , vol.51 , pp. 768-774
    • Patton, J.H.1    Stanford, M.S.2    Barratt, E.S.3
  • 23
    • 34247536724 scopus 로고    scopus 로고
    • Outcomes of eating disorders: A systematic review of the literature
    • Berkman ND, Lohr KN, Bulik CM,. Outcomes of eating disorders: A systematic review of the literature. Int J Eat Disord 2007; 40: 293-309.
    • (2007) Int J Eat Disord , vol.40 , pp. 293-309
    • Berkman, N.D.1    Lohr, K.N.2    Bulik, C.M.3
  • 25
    • 84873687326 scopus 로고    scopus 로고
    • Treatment for severe and enduring anorexia nervosa: A review
    • Hay PJ, Touyz S, Sud R,. Treatment for severe and enduring anorexia nervosa: A review. Aust N Z J Psychiatry 2012; 46: 1136-1144.
    • (2012) Aust N Z J Psychiatry , vol.46 , pp. 1136-1144
    • Hay, P.J.1    Touyz, S.2    Sud, R.3
  • 26
    • 84916638038 scopus 로고    scopus 로고
    • Attachment and eating disorders: A review of current research
    • Tasca GA, Balfour L,. Attachment and eating disorders: A review of current research. Int J Eat Disord 2014; 47: 710-717.
    • (2014) Int J Eat Disord , vol.47 , pp. 710-717
    • Tasca, G.A.1    Balfour, L.2
  • 27
    • 0034947095 scopus 로고    scopus 로고
    • Ten-year follow-up of adolescent-onset anorexia nervosa: Psychiatric disorders and overall functioning scales
    • Wentz E, Gillberg C, Gillberg IC, Rastam M,. Ten-year follow-up of adolescent-onset anorexia nervosa: Psychiatric disorders and overall functioning scales. J Child Psychol Psychiatry 2001; 42: 613-622.
    • (2001) J Child Psychol Psychiatry , vol.42 , pp. 613-622
    • Wentz, E.1    Gillberg, C.2    Gillberg, I.C.3    Rastam, M.4
  • 28
    • 1642304002 scopus 로고    scopus 로고
    • Eating disorders and the serotonin connection: State, trait and developmental effects
    • Steiger H,. Eating disorders and the serotonin connection: State, trait and developmental effects. J Psychiatry Neurosci 2004; 29: 20-29.
    • (2004) J Psychiatry Neurosci , vol.29 , pp. 20-29
    • Steiger, H.1
  • 29
    • 84883812822 scopus 로고    scopus 로고
    • Daily patterns of anxiety in anorexia nervosa: Associations with eating disorder behaviors in the natural environment
    • Lavender JM, De Young KP, Wonderlich SA, Crosby RD, Engel SG, Mitchell JE, et al., Daily patterns of anxiety in anorexia nervosa: Associations with eating disorder behaviors in the natural environment. J Abnorm Psychol 2013; 122: 672-683.
    • (2013) J Abnorm Psychol , vol.122 , pp. 672-683
    • Lavender, J.M.1    De Young, K.P.2    Wonderlich, S.A.3    Crosby, R.D.4    Engel, S.G.5    Mitchell, J.E.6
  • 30
    • 0035094531 scopus 로고    scopus 로고
    • Growth/differentiation factor 7 is preferentially expressed in the primary motor area of the monkey neocortex
    • Watakabe A, Fujita H, Hayashi M, Yamamori T,. Growth/differentiation factor 7 is preferentially expressed in the primary motor area of the monkey neocortex. J Neurochem 2001; 76: 1455-1464.
    • (2001) J Neurochem , vol.76 , pp. 1455-1464
    • Watakabe, A.1    Fujita, H.2    Hayashi, M.3    Yamamori, T.4
  • 31
    • 84864878382 scopus 로고    scopus 로고
    • Dopamine in anorexia nervosa: A systematic review
    • Kontis D, Theochari E,. Dopamine in anorexia nervosa: A systematic review. Behav Pharmacol 2012; 23: 496-515.
    • (2012) Behav Pharmacol , vol.23 , pp. 496-515
    • Kontis, D.1    Theochari, E.2
  • 32
    • 0032213969 scopus 로고    scopus 로고
    • Neuronal patterning by BMPs: A requirement for GDF7 in the generation of a discrete class of commissural interneurons in the mouse spinal cord
    • Lee KJ, Mendelsohn M, Jessell TM,. Neuronal patterning by BMPs: A requirement for GDF7 in the generation of a discrete class of commissural interneurons in the mouse spinal cord. Genes Dev 1998; 12: 3394-3407.
    • (1998) Genes Dev , vol.12 , pp. 3394-3407
    • Lee, K.J.1    Mendelsohn, M.2    Jessell, T.M.3
  • 33
    • 32544457443 scopus 로고    scopus 로고
    • WAVE signalling: From biochemistry to biology
    • Soderling SH, Scott JD,. WAVE signalling: From biochemistry to biology. Biochem Soc Tran 2006; 34: 73-76.
    • (2006) Biochem Soc Tran , vol.34 , pp. 73-76
    • Soderling, S.H.1    Scott, J.D.2
  • 34
    • 34548259213 scopus 로고    scopus 로고
    • WAVE2 regulates high-affinity integrin binding by recruiting vinculin and talin to the immunological synapse
    • Nolz JC, Medeiros RB, Mitchell JS, Zhu P, Freedman BD, Shimizu Y, et al., WAVE2 regulates high-affinity integrin binding by recruiting vinculin and talin to the immunological synapse. Mol Cell Biol 2007; 27: 5986-6000.
    • (2007) Mol Cell Biol , vol.27 , pp. 5986-6000
    • Nolz, J.C.1    Medeiros, R.B.2    Mitchell, J.S.3    Zhu, P.4    Freedman, B.D.5    Shimizu, Y.6
  • 35
    • 84888437729 scopus 로고    scopus 로고
    • Methylation of the dopamine D2 receptor (DRD2) gene promoter in women with a bulimia-spectrum disorder: Associations with borderline personality disorder and exposure to childhood abuse
    • Groleau P, Joober R, Israel M, Zeramdini N, DeGuzman R, Steiger H,. Methylation of the dopamine D2 receptor (DRD2) gene promoter in women with a bulimia-spectrum disorder: Associations with borderline personality disorder and exposure to childhood abuse. J Psychiatr Res 2014; 48: 121-127.
    • (2014) J Psychiatr Res , vol.48 , pp. 121-127
    • Groleau, P.1    Joober, R.2    Israel, M.3    Zeramdini, N.4    DeGuzman, R.5    Steiger, H.6
  • 36
    • 84875228188 scopus 로고    scopus 로고
    • Methylation of the glucocorticoid receptor gene promoter in bulimic women: Associations with borderline personality disorder, suicidality, and exposure to childhood abuse
    • Steiger H, Labonte B, Groleau P, Turecki G, Israel M,. Methylation of the glucocorticoid receptor gene promoter in bulimic women: Associations with borderline personality disorder, suicidality, and exposure to childhood abuse. Int J Eat Disord 2013; 46: 246-255.
    • (2013) Int J Eat Disord , vol.46 , pp. 246-255
    • Steiger, H.1    Labonte, B.2    Groleau, P.3    Turecki, G.4    Israel, M.5
  • 37
    • 84902478625 scopus 로고    scopus 로고
    • Methylation of BDNF in women with bulimic eating syndromes: Associations with childhood abuse and borderline personality disorder
    • Thaler L, Gauvin L, Joober R, Groleau P, de Guzman R, Ambalavanan A, et al., Methylation of BDNF in women with bulimic eating syndromes: Associations with childhood abuse and borderline personality disorder. Prog Neuropsychopharmacol Biol Psychiatry 2014; 54C: 43-49.
    • (2014) Prog Neuropsychopharmacol Biol Psychiatry , vol.54 C , pp. 43-49
    • Thaler, L.1    Gauvin, L.2    Joober, R.3    Groleau, P.4    De Guzman, R.5    Ambalavanan, A.6
  • 38
    • 84862667231 scopus 로고    scopus 로고
    • Peripheral SLC6A4 DNA methylation is associated with in vivo measures of human brain serotonin synthesis and childhood physical aggression
    • Wang D, Szyf M, Benkelfat C, Provencal N, Turecki G, Caramaschi D, et al., Peripheral SLC6A4 DNA methylation is associated with in vivo measures of human brain serotonin synthesis and childhood physical aggression. PLoS One 2012; 7: e39501.
    • (2012) PLoS One , vol.7 , pp. e39501
    • Wang, D.1    Szyf, M.2    Benkelfat, C.3    Provencal, N.4    Turecki, G.5    Caramaschi, D.6
  • 39
    • 84892159781 scopus 로고    scopus 로고
    • Differential DNA methylation regions in cytokine and transcription factor genomic loci associate with childhood physical aggression
    • Provencal N, Suderman MJ, Caramaschi D, Wang D, Hallett M, Vitaro F, et al., Differential DNA methylation regions in cytokine and transcription factor genomic loci associate with childhood physical aggression. PLoS One 2013; 8: e71691.
    • (2013) PLoS One , vol.8 , pp. e71691
    • Provencal, N.1    Suderman, M.J.2    Caramaschi, D.3    Wang, D.4    Hallett, M.5    Vitaro, F.6
  • 40
    • 68349091505 scopus 로고    scopus 로고
    • The early life environment and the epigenome
    • Szyf M,. The early life environment and the epigenome. Biochim Biophys Acta 2009; 1790: 878-885.
    • (2009) Biochim Biophys Acta , vol.1790 , pp. 878-885
    • Szyf, M.1
  • 41
    • 84925414806 scopus 로고    scopus 로고
    • Genetic and early environmental influences on the serotonin system: Consequences for brain development and risk for psychopathology
    • Booij L, Tremblay RE, Szyf M, Benkelfat C,. Genetic and early environmental influences on the serotonin system: Consequences for brain development and risk for psychopathology. J Psychiatry Neurosci 2014; 39: 140099.
    • (2014) J Psychiatry Neurosci , vol.39 , pp. 140099
    • Booij, L.1    Tremblay, R.E.2    Szyf, M.3    Benkelfat, C.4
  • 43
    • 84861077168 scopus 로고    scopus 로고
    • Antidepressant treatment is associated with epigenetic alterations in the promoter of P11 in a genetic model of depression
    • Melas PA, Rogdaki M, Lennartsson A, Bjork K, Qi H, Witasp A, et al., Antidepressant treatment is associated with epigenetic alterations in the promoter of P11 in a genetic model of depression. Int J Neuropsychopharmacol 2012; 15: 669-679.
    • (2012) Int J Neuropsychopharmacol , vol.15 , pp. 669-679
    • Melas, P.A.1    Rogdaki, M.2    Lennartsson, A.3    Bjork, K.4    Qi, H.5    Witasp, A.6
  • 44
    • 79951698211 scopus 로고    scopus 로고
    • Fluoxetine increases hippocampal neurogenesis and induces epigenetic factors but does not improve functional recovery after traumatic brain injury
    • Wang Y, Neumann M, Hansen K, Hong SM, Kim S, Noble-Haeusslein LJ, et al., Fluoxetine increases hippocampal neurogenesis and induces epigenetic factors but does not improve functional recovery after traumatic brain injury. J Neurotrauma 2011; 28: 259-268.
    • (2011) J Neurotrauma , vol.28 , pp. 259-268
    • Wang, Y.1    Neumann, M.2    Hansen, K.3    Hong, S.M.4    Kim, S.5    Noble-Haeusslein, L.J.6


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