Yapsin 2

Handbook of Proteolytic Enzymes, Second Edition: Volume 1: Aspartic and Metallo Peptidases

Volumn 1, Issue , 2004, Pages 132-133

  Fuller, Robert S ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 84944031120     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1016/B978-0-12-079611-3.50042-2     Document Type: Chapter

References (8)

1. J. Ash, M. Dominguez, J.J. Bergeron, D.Y. Thomas and Y. Bourbonnais (1995) The yeast proprotein convertase encoded by YAP3 is a glycophosphatidylinositol-anchored protein that localizes to the plasma membrane. J. Biol. Chem. 270 20847-20854.
2. N.X. Cawley, M. Wong, L.P. Pu, W. Tam and Y.P. Loh (1995) Secretion of yeast aspartic protease 3 is regulated by its carboxyterminal tail: characterization of secreted YAP3p. Biochemistry 34 7430-7437.
3. K.S. Copley, S.M. Alm, D.A. Schooley and W.E. Courchesne (1998) Expression, processing and secretion of a proteolytically-sensitive insect diuretic hormone by Saccharomyces cerevisiae requires the use of a yeast strain lacking genes encoding the Yap3 and Mkc7 endoproteases found in the secretory pathway. Biochem. J. 330 1333-1340.
4. M. Egel-Mitani, H.P. Flygenring and M.T. Hansen (1990) A novel aspartyl protease allowing KEX2-independent MFα propheromone processing in yeast. Yeast 6 127-137.
5. H. Komano and R.S. Fuller (1995) Shared functions in vivo of a glycosyl-phosphatidylinositol-linked aspartyl protease, Mkc7, and the proprotein-processing protease Kex2 in yeast. Proc. Natl. Acad. Sci. USA 92 10752-10756.
6. H. Komano, M. Seeger, S.E. Gandy, G.T. Wang, G.A. Krafft and R.S. Fuller (1998) Involvement of cell surface glycosylphosphatidylinositol-linked aspartyl proteases in α-secretase type cleavage and ectodomain solubilization of human Alzheimer β-amyloid precursor protein in yeast. J. Biol. Chem. 273 31648-31651.
7. H. Komano, N. Rockwell, G. Wang, G. Krafft and R.S. Fuller (1999) Purification and characterization of the yeast GPI-anchored, monobasic-specific aspartyl protease yapsin 2 (Mkc7p). J. Biol. Chem. 274 24431-24437.
8. W. Zhang, D. Espinoza, V. Hines, M. Innis, P. Mehta and D.L. Miller (1997) Characterization of beta-amyloid peptide precursor processing by the yeast Yap3 and Mkc7 proteases. Biochim. Biophys. Acta 1359 110-122.