Imaging of fluid in cancer patients treated with systemic therapy: Chemotherapy, molecular targeted therapy, and hematopoietic stem cell transplantation

American Journal of Roentgenology

Volumn 205, Issue 4, 2015, Pages 709-719

  Keraliya, Abhishek R ^a   Rosenthal, Michael H ^a   Krajewski, Katherine M ^a   Jagannathan, Jyothi P ^a   Shinagare, Atul B ^a   Tirumani, Sree Harsha ^a   Ramaiya, Nikhil H ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Fluid; Hematopoietic stem cell transplantation; Molecular targeted therapy

Indexed keywords

ASPARAGINASE; BEVACIZUMAB; BUSULFAN; CARBOPLATIN; CETUXIMAB; CISPLATIN; CYCLOPHOSPHAMIDE; DABRAFENIB; DACARBAZINE; DASATINIB; DOCETAXEL; DOXORUBICIN; ERLOTINIB; EVEROLIMUS; FLUOROURACIL; GEMCITABINE; IMATINIB; IPILIMUMAB; LAPATINIB; MITOMYCIN; NILOTINIB; OXALIPLATIN; PACLITAXEL; PAZOPANIB; SORAFENIB; SUNITINIB; TEMSIROLIMUS; TRAMETINIB; TRASTUZUMAB; UNINDEXED DRUG; ANTINEOPLASTIC AGENT;

ABDOMINAL FLUID RETENTION; ABDOMINAL PAIN; ACUTE KIDNEY FAILURE; ACUTE LYMPHOBLASTIC LEUKEMIA; ACUTE PANCREATITIS; ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION; AMYLASE BLOOD LEVEL; ANASARCA; ASCITES; AUTOLOGOUS HEMATOPOIETIC STEM CELL TRANSPLANTATION; BILIRUBIN BLOOD LEVEL; BLEEDING; BREAST CANCER; BREAST METASTASIS; CANCER CHEMOTHERAPY; CANCER MORTALITY; CANCER PATIENT; CAPILLARY PERMEABILITY; CARCINOMATOSIS; CARDIOMYOPATHY; CARDIOTOXICITY; CHOLESTASIS; CHRONIC MYELOID LEUKEMIA; COLITIS; COLON CANCER; COLORECTAL CANCER; COMPUTER ASSISTED TOMOGRAPHY; CONGESTIVE HEART FAILURE; CONTRAST ENHANCEMENT; COUGHING; DIARRHEA; DIFFERENTIAL DIAGNOSIS; DISEASE ASSOCIATION; DOPPLER ECHOGRAPHY; DRUG MECHANISM; DYSPNEA; ECHOCARDIOGRAPHY; EDEMA; EDEMATOUS PANCREAS; ENDOTHELIUM INJURY; ENGRAFTMENT SYNDROME; ENTERITIS; EPIDERMAL GROWTH FACTOR RECEPTOR 2 POSITIVE BREAST CANCER; ESOPHAGUS CANCER; FLUID RETENTION; GASTROINTESTINAL STROMAL TUMOR; GLIOBLASTOMA; GLOMERULAR INJURY; GRAFT VERSUS HOST REACTION; HEART ARRHYTHMIA; HEART FAILURE; HEART LEFT VENTRICLE EJECTION FRACTION; HEART LEFT VENTRICLE FAILURE; HEART MUSCLE CELL; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HEPATITIS; HEPATOMEGALY; HUMAN; HYPERKALEMIA; HYPERPHOSPHATEMIA; HYPERTENSION; HYPERURICEMIA; HYPOALBUMINEMIA; HYPOCALCEMIA; HYPOPHYSITIS; IMMUNOSUPPRESSIVE TREATMENT; INCIDENCE; INTRAPANCREATIC FLUID COLLECTION; JAUNDICE; KIDNEY CANCER; KIDNEY DISEASE; KIDNEY TUBULE NECROSIS; LIVER CELL DAMAGE; LIVER CIRRHOSIS; LIVER DYSFUNCTION; LIVER FAILURE; LIVER NECROSIS; LIVER TOXICITY; LIVER VEIN OBSTRUCTION; LIVER VENOOCCLUSIVE DISEASE; LUNG EDEMA; LUNG TOXICITY; LYMPHANGITIC CARCINOMATOSIS; LYMPHOMA; MELANOMA; MOLECULARLY TARGETED THERAPY; MORBIDITY; NEPHROTIC SYNDROME; NEPHROTOXICITY; NON SMALL CELL LUNG CANCER; NONCARDIOGENIC LUNG EDEMA; NONHODGKIN LYMPHOMA; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PANCREAS CANCER; PANCREAS DISEASE; PANCREATITIS; PEPTOCLOSTRIDIUM DIFFICILE; PERICARDIAL EFFUSION; PERICARDITIS; PERINEPHRIC STRANDING; PERIPANCREATIC FLUID COLLECTION; PERIPHERAL EDEMA; PERIPORTAL EDEMA; PLEURA EFFUSION; PORTAL HYPERTENSION; PORTAL VEIN THROMBOSIS; POSITRON EMISSION TOMOGRAPHY; POSTOPERATIVE COMPLICATION; PRIORITY JOURNAL; PROTEINURIA; PSEUDOCIRRHOSIS; PSEUDOMEMBRANOUS COLITIS; PULMONARY HYPERTENSION; RASH; RETROSPECTIVE STUDY; REVIEW; RISK FACTOR; SEPSIS; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; SOLID TUMOR; SPLENOMEGALY; STEATOSIS; SUBCUTANEOUS EDEMA; SUPERFICIAL EDEMA; SYNGENIC HEMATOPOIETIC STEM CELL TRANSPLANTATION; THORAX PAIN; THROMBOEMBOLISM; THROMBOTIC THROMBOCYTOPENIC PURPURA; THYROID CANCER; TREATMENT RESPONSE; TRIACYLGLYCEROL LIPASE BLOOD LEVEL; TUMOR LYSIS SYNDROME; TYPHLITIS; VOLUME OVERLOAD; WEIGHT GAIN; WHOLE BODY RADIATION; ADVERSE EFFECTS; COMPLICATION; DIAGNOSTIC IMAGING; NEOPLASMS; PLEURAL EFFUSION;

ANTINEOPLASTIC AGENTS; ASCITES; DIAGNOSTIC IMAGING; EDEMA; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMANS; MOLECULAR TARGETED THERAPY; NEOPLASMS; PERICARDIAL EFFUSION; PLEURAL EFFUSION;

EID: 84943652834     PISSN: 0361803X     EISSN: 15463141     Source Type: Journal    
DOI: 10.2214/AJR.15.14459     Document Type: Review

References (65)

1. Risson JR, Macovei I, Loock M, Paquette B, Martin M, Delabrousse E. Cirrhotic and malignant ascites: differential CT diagnosis. Diagn Interv Imaging 2012; 93:365-370
2. Maor Y, Malnick S. Liver injury induced by anticancer chemotherapy and radiation therapy. Int J Hepatol 2013; 2013:815105
3. King PD, Perry MC. Hepatotoxicity of chemotherapy. Oncologist 2001; 6:162-176
4. Iacovelli R, Palazzo A, Procopio G, et al. Incidence and relative risk of hepatic toxicity in patients treated with anti-angiogenic tyrosine kinase inhibitors for malignancy. Br J Clin Pharmacol 2014; 77:929-938
5. Azim HA Jr, Agbor-Tarh D, Bradbury I, et al. Pattern of rash, diarrhea, and hepatic toxicities secondary to lapatinib and their association with age and response to neoadjuvant therapy: analysis from the NeoALTTO trial. J Clin Oncol 2013; 31:4504-4511
6. Saif MW. Erlotinib-induced acute hepatitis in a patient with pancreatic cancer. Clin Adv Hematol Oncol 2008; 6:191-199
7. Kim KW, Ramaiya NH, Krajewski KM, et al. Ipilimumab associated hepatitis: imaging and clinicopathologic findings. Invest New Drugs 2013; 31:1071-1077
8. Qayyum A, Lee GK, Yeh BM, Allen JN, Venook AP, Coakley FV. Frequency of hepatic contour abnormalities and signs of portal hypertension at CT in patients receiving chemotherapy for breast cancer metastatic to the liver. Clin Imaging 2007; 31:6-10
9. Kang SP, Taddei T, McLennan B, Lacy J. Pseudocirrhosis in a pancreatic cancer patient with liver metastases: A case report of complete resolution of pseudocirrhosis with an early recognition and management. World J Gastroenterol 2008; 14:1622-1624
10. Harry BL, Smith ML, Burton JR, Dasari A, Eckhardt SG, Diamond JR. Medullary thyroid cancer and pseudocirrhosis: case report and literature review. Curr Oncol 2012; 19:e36-e41
11. McDonald GB, Hinds MS, Fisher LD, et al. Venoocclusive disease of the liver and multiorgan failure after bone marrow transplantation: A cohort study of 355 patients. Ann Intern Med 1993; 118:255-267
12. Seo AN, Kim H. Sinusoidal obstruction syndrome after oxaliplatin-based chemotherapy. Clin Mol Hepatol 2014; 20:81-84
13. DeLeve LD, Shulman HM, McDonald GB. Toxic injury to hepatic sinusoids: sinusoidal obstruction syndrome (veno-occlusive disease). Semin Liver Dis 2002; 22:27-42
14. Cefalo MG, Maurizi P, Arlotta A, et al. Hepatic veno-occlusive disease: A chemotherapy-related toxicity in children with malignancies. Paediatr Drugs 2010; 12:277-284
15. Coppell JA, Brown SA, Perry DJ. Veno-occlusive disease: cytokines, genetics, and haemostasis. Blood Rev 2003; 17:63-70
16. Deeg KH, Glockel U, Richter R, Beck J. Diagnosis of veno-occlusive disease of the liver by colorcoded Doppler sonography. Pediatr Radiol 1993; 23:134-136
17. Lassau N, Auperin A, Leclere J, Bennaceur A, Valteau-Couanet D, Hartmann O. Prognostic value of Doppler-ultrasonography in hepatic veno-occlusive disease. Transplantation 2002; 74:60-66
18. Erturk SM, Mortele KJ, Binkert CA, et al. CT features of hepatic venoocclusive disease and hepatic graftversus-host disease in patients after hematopoietic stem cell transplantation. AJR 2006; 186:1497-1501
19. Donadon M, Vauthey JN, Loyer EM, Charnsangavej C, Abdalla EK. Portal thrombosis and steatosis after preoperative chemotherapy with FOLFIRIbevacizumab for colorectal liver metastases. World J Gastroenterol 2006; 12:6556-6558
20. Lawson TL, Thorsen MK, Erickson SJ, Perret RS, Quiroz FA, Foley WD. Periportal halo: A CT sign of liver disease. Abdom Imaging 1993; 18:42-46
21. Vinklerová I, Procházka M, Procházka V, Urbánek K. Incidence, severity, and etiology of drug-induced acute pancreatitis. Dig Dis Sci 2010; 55:2977-2981
22. Raja RA, Schmiegelow K, Frandsen TL. Asparaginase-associated pancreatitis in children. Br J Haematol 2012; 159:18-27
23. Pezzilli R, Fabbri D, Imbrogno A, Corinaldesi R. Tyrosine kinase inhibitors, pancreatic hyperenzymemia and acute pancreatitis: A review. Recent Pat Inflamm Allergy Drug Discov 2011; 5:165-168
24. Tirumani SH, Jagannathan JP, Shinagare AB, Kim K, Krajewski KM, Ramaiya NH. Acute pancreatitis associated with molecular targeted therapies: A retrospective review of the clinico-radiological features, management and outcome. Pancreatology 2013; 13:461-467
25. Stein A, Voigt W, Jordan K. Chemotherapy-induced diarrhea: pathophysiology, frequency and guideline-based management. Ther Adv Med Oncol 2010; 2:51-63
26. Parithivel K, Ramaiya N, Jagannathan JP, et al. Everolimus-and temsirolimus-associated enteritis: report of three cases. J Clin Oncol 2011; 29:e404-e406
27. Wolchok JD, Neyns B, Linette G, et al. Ipilimumab monotherapy in patients with pretreated advanced melanoma: A randomised, double-blind, multicentre, phase 2, dose-ranging study. Lancet Oncol 2010; 11:155-164
28. Kim KW, Ramaiya NH, Krajewski KM, et al. Ipilimumab-associated colitis: CT findings. AJR 2013; 200:[web]W468-W474
29. Humphreys BD, Soiffer RJ, Magee CC. Renal failure associated with cancer and its treatment: an update. J Am Soc Nephrol 2005; 16:151-161
30. Izzedine H, Massard C, Spano JP, Goldwasser F, Khayat D, Soria JC. VEGF signalling inhibitioninduced proteinuria: mechanisms, significance and management. Eur J Cancer 2010; 46:439-448
31. Izzedine H, Escudier B, Lhomme C, et al. Kidney diseases associated with anti-vascular endothelial growth factor (VEGF): An 8-year observational study at a single center. Medicine 2014; 93:333-339
32. Rampello E, Fricia T, Malaguarnera M. The management of tumor lysis syndrome. Nat Clin Pract Oncol 2006; 3:438-447
33. Yeh ET, Bickford CL. Cardiovascular complications of cancer therapy: incidence, pathogenesis, diagnosis, and management. J Am Coll Cardiol 2009; 53:2231-2247
34. Broder H, Gottlieb RA, Lepor NE. Chemotherapy and cardiotoxicity. Rev Cardiovasc Med 2008; 9:75-83
35. Jiji RS, Kramer CM, Salerno M. Non-invasive imaging and monitoring cardiotoxicity of cancer therapeutic drugs. J Nucl Cardiol 2012; 19:377-388
36. Wouters KA, Kremer LC, Miller TL, Herman EH, Lipshultz SE. Protecting against anthracycline-induced myocardial damage: A review of the most promising strategies. Br J Haematol 2005; 131:561-578
37. Kremer LC, van Dalen EC, Offringa M, Ottenkamp J, Voute PA. Anthracycline-induced clinical heart failure in a cohort of 607 children: long-term follow-up study. J Clin Oncol 2001; 19:191-196
38. Volkova M, Russell R 3rd. Anthracycline cardiotoxicity: prevalence, pathogenesis and treatment. Curr Cardiol Rev 2011; 7:214-220
39. Pai VB, Nahata MC. Cardiotoxicity of chemotherapeutic agents: incidence, treatment and prevention. Drug Saf 2000; 22:263-302
40. Ho MY, Mackey JR. Presentation and management of docetaxel-related adverse effects in patients with breast cancer. Cancer Manag Res 2014; 6:253-259
41. de Forni M, Malet-Martino MC, Jaillais P, et al. Cardiotoxicity of high-dose continuous infusion fluorouracil: A prospective clinical study. J Clin Oncol 1992; 10:1795-1801
42. Slamon D, Eiermann W, Robert N, et al. Adjuvant trastuzumab in HER2-positive breast cancer. N Engl J Med 2011; 365:1273-1283
43. Fiúza M. Cardiotoxicity associated with trastuzumab treatment of HER2+ breast cancer. Adv Ther 2009; 26(suppl 1):S9-S17
44. Zeglinski M, Ludke A, Jassal DS, Singal PK. Trastuzumab-induced cardiac dysfunction: A 'dualhit.' Exp Clin Cardiol 2011; 16:70-74
45. Huszno J, Les D, Sarzyczny-Slota D, Nowara E. Cardiac side effects of trastuzumab in breast cancer patients: single center experiences. Contemp Oncol 2013; 17:190-195
46. Guarneri V, Lenihan DJ, Valero V, et al. Long-term cardiac tolerability of trastuzumab in metastatic breast cancer: The M. D. Anderson Cancer Center experience. J Clin Oncol 2006; 24:4107-4115
47. Choueiri TK, Mayer EL, Je Y, et al. Congestive heart failure risk in patients with breast cancer treated with bevacizumab. J Clin Oncol 2011; 29:632-638
48. Kantarjian H, Shah NP, Hochhaus A, et al. Dasatinib versus imatinib in newly diagnosed chronicphase chronic myeloid leukemia. N Engl J Med 2010; 362:2260-2270
49. Keating GM, Lyseng-Williamson KA, McCormack PL, Keam SJ. Dasatinib: A guide to its use in chronic myeloid leukemia in the EU. BioDrugs 2013; 27:275-279
50. Kerkela R, Grazette L, Yacobi R, et al. Cardiotoxicity of the cancer therapeutic agent imatinib mesylate. Nat Med 2006; 12:908-916
51. Brixey AG, Light RW. Pleural effusions due to dasatinib. Curr Opin Pulm Med 2010; 16:351-356
52. Masiello D, Gorospe G 3rd, Yang AS. The occurrence and management of fluid retention associated with TKI therapy in CML, with a focus on dasatinib. J Hematol Oncol 2009; 2:46
53. Ascierto PA, Kirkwood JM, Grob JJ, et al. The role of BRAF V600 mutation in melanoma. J Transl Med 2012; 10:85
54. Flaherty KT, Infante JR, Daud A, et al. Combined BRAF and MEK inhibition in melanoma with BRAF V600 mutations. N Engl J Med 2012; 367:1694-1703
55. Dy GK, Adjei AA. Understanding, recognizing, and managing toxicities of targeted anticancer therapies. CA Cancer J Clin 2013; 63:249-279
56. Briasoulis E, Pavlidis N. Noncardiogenic pulmonary edema: an unusual and serious complication of anticancer therapy. Oncologist 2001; 6:153-161
57. Milne EN, Pistolesi M, Miniati M, Giuntini C. The radiologic distinction of cardiogenic and noncardiogenic edema. AJR 1985; 144:879-894
58. Copelan EA. Hematopoietic stem-cell transplantation. N Engl J Med 2006; 354:1813-1826
59. Lim do H, Lee J, Lee HG, et al. Pulmonary complications after hematopoietic stem cell transplantation. J Korean Med Sci 2006; 21:406-411
60. Maiolino A, Biasoli I, Lima J, Portugal AC, Pulcheri W, Nucci M. Engraftment syndrome following autologous hematopoietic stem cell transplantation: definition of diagnostic criteria. Bone Marrow Transplant 2003; 31:393-397
61. Jagannathan JP, Ramaiya N, Gill RR, Alyea EP 3rd, Ros P. Imaging of complications of hematopoietic stem cell transplantation. Radiol Clin North Am 2008; 46:397-417
62. Ball LM, Egeler RM, Party EPW. Acute GvHD: pathogenesis and classification. Bone Marrow Transplant 2008; 41(suppl 2):S58-S64
63. Brodoefel H, Bethge W, Vogel M, et al. Early and late-onset acute GvHD following hematopoietic cell transplantation: CT features of gastrointestinal involvement with clinical and pathological correlation. Eur J Radiol 2010; 73:594-600
64. Lee JH, Lim GY, Im SA, Chung NG, Hahn ST. Gastrointestinal complications following hematopoietic stem cell transplantation in children. Korean J Radiol 2008; 9:449-457
65. Ash L, Baker ME, O'Malley CM Jr, Gordon SM, Delaney CP, Obuchowski NA. Colonic abnormalities on CT in adult hospitalized patients with Clostridium difficile colitis: prevalence and significance of findings. AJR 2006; 186:1393-1400