Data in support of a functional analysis of splicing mutations in the IDS gene and the use of antisense oligonucleotides to exploit an alternative therapy for MPS II

Data in Brief

Volumn 5, Issue , 2015, Pages 810-817

  Matos, Liliana ^a,b   Gonçalves, Vânia ^c   Pinto, Eugénia ^d   Laranjeira, Francisco ^d   Prata, Maria João ^b   Jordan, Peter ^c   Desviat, Lourdes R ^e,f,g   Pérez, Belén ^e,f,g   Alves, Sandra ^a  

^a NATIONAL INSTITUTE OF HEALTH   (Portugal)

^b UNIVERSITY OF PORTO   (Portugal)

^c NATIONAL INSTITUTE OF HEALTH DR RICARDO JORGE   (Portugal)

^d UP   (Portugal)

^e UNIVERSIDAD AUTÓNOMA DE MADRID   (Spain)

^f CENTRO DE INVESTIGACIÓN BIOMÉDICA EN RED DE ENFERMEDADES RARAS CIBERER   (Spain)

^g HOSPITAL UNIVERSITARIO LA PAZ IDIPAZ   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

GENE THERAPY; OLIGONUCLEOTIDES;

ALTERNATIVE THERAPY; ANTISENSE OLIGONUCLEOTIDES; MINIGENES; OVEREXPRESSIONS; REGULATORY SEQUENCES; RNA INTERFERENCE; WILD TYPES;

FUNCTIONAL ANALYSIS;

EID: 84943605593     PISSN: None     EISSN: 23523409     Source Type: Journal    
DOI: 10.1016/j.dib.2015.10.011     Document Type: DP

References (5)

1. Matos L., Gonçalves V., Pinto E., Laranjeira F., Prata M.J., Jordan P., Desviat L.R., Pérez B., Alves S. Functional analysis of splicing mutations in the IDS gene and the use of antisense oligonucleotides to exploit an alternative therapy for MPS II. Biochim. Biophys. Acta 2015, 1852:2712-2721.
2. Neufeld E.F., Muenzer J. Part 12: 78. The mucopolysaccharidoses. The Metabolic and Molecular Bases of Inherited Disease 2001, Vol. II:2465-2495. McGraw-Hill, New York. 8th ed.
3. Cartegni L., Wang J., Zhu Z., Zhang M.Q., Krainer A.R. ESEfinder: a web resource to identify exonic splicing enhancers. Nucleic Acids Res. 2003, 31:3568-3571.
4. Smith P.J., Zhang C., Wang J., Chew S.L., Zhang M.Q., Krainer A.R. An increased specificity score matrix for the prediction of SF2/ASF-specific exonic splicing enhancers. Hum. Mol. Genet. 2006, 15:2490-2508.
5. Stamm S., Riethoven J.J., Le Texier V., Gopalakrishnan C., Kumanduri V., Tang Y., Barbosa-Morais N.L., Thanaraj T.A. ASD: a bioinformatics resource on alternative splicing. Nucleic Acids Res. 2006, 34:D46-D55.