Marijuana use is associated with worse outcomes in symptom severity and violent behavior in patients with posttraumatic stress disorder

Journal of Clinical Psychiatry

Volumn 76, Issue 9, 2015, Pages 1174-1180

  Wilkinson, Samuel T ^a   Stefanovics, Elina ^a,b   Rosenheck, Robert A ^a,b  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VA CONNECTICUT HEALTHCARE SYSTEM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ALCOHOL CONSUMPTION; ARTICLE; CANNABIS USE; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE COURSE; DISEASE SEVERITY; DRUG USE; DSM-III; DSM-IV; EMPLOYMENT; FEMALE; FOLLOW UP; HUMAN; LONGITUDINAL STUDY; MAJOR CLINICAL STUDY; MALE; OBSERVATIONAL STUDY; POSTTRAUMATIC STRESS DISORDER; PRIORITY JOURNAL; PROGNOSIS; VETERAN; VIOLENCE; CANNABIS SMOKING; CASE CONTROL STUDY; DRINKING BEHAVIOR; MIDDLE AGED; PSYCHOLOGY; SEVERITY OF ILLNESS INDEX; TIME;

ALCOHOL DRINKING; CASE-CONTROL STUDIES; DRUG USERS; EMPLOYMENT; FEMALE; HUMANS; LONGITUDINAL STUDIES; MALE; MARIJUANA SMOKING; MIDDLE AGED; SEVERITY OF ILLNESS INDEX; STRESS DISORDERS, POST-TRAUMATIC; TIME FACTORS; VETERANS; VIOLENCE;

EID: 84943558970     PISSN: 01606689     EISSN: None     Source Type: Journal    
DOI: 10.4088/JCP.14m09475     Document Type: Article

References (41)

1. Volkow ND, Baler RD, Compton WM, et al. Adverse health effects of marijuana use. N Engl J Med. 2014;370(23):2219-2227.
2. 23 legal medical marijuana states and DC: laws, fees, and possession limits. Procon.org Web site. http://medicalmarijuana.procon.org/view.resource.php?resourceID=000881. Accessed January 12, 2015.
3. Wilkinson ST, D'Souza DC. Problems with the medicalization of marijuana. JAMA. 2014;311(23):2377-2378.
4. Stern CA, Gazarini L, Takahashi RN, et al. On disruption of fear memory by reconsolidation blockade: evidence from cannabidiol treatment. Neuropsychopharmacology. 2012;37(9):2132-2142.
5. Das RK, Kamboj SK, Ramadas M, et al. Cannabidiol enhances consolidation of explicit fear extinction in humans. Psychopharmacology (Berl). 2013;226(4):781-792.
6. Bremner JD, Southwick SM, Darnell A, et al. Chronic PTSD in Vietnam combat veterans: course of illness and substance abuse. Am J Psychiatry. 1996;153(3):369-375.
7. Bonn-Miller MO, Vujanovic AA, Feldner MT, et al. Posttraumatic stress symptom severity predicts marijuana use coping motives among traumatic event-exposed marijuana users. J Trauma Stress. 2007;20(4):577-586.
8. Boden MT, Babson KA, Vujanovic AA, et al. Posttraumatic stress disorder and cannabis use characteristics among military veterans with cannabis dependence. Am J Addict. 2013;22(3):277-284.
9. Bonn-Miller MO, Vujanovic AA, Boden MT, et al. Posttraumatic stress, difficulties in emotion regulation, and coping-oriented marijuana use. Cogn Behav Ther. 2011;40(1):34-44.
10. Cornelius JR, Kirisci L, Reynolds M, et al. PTSD contributes to teen and young adult cannabis use disorders. Addict Behav. 2010;35(2):91-94.
11. Lipschitz DS, Rasmusson AM, Anyan W, et al. Posttraumatic stress disorder and substance use in inner-city adolescent girls. J Nerv Ment Dis. 2003;191(11):714-721.
12. Cougle JR, Bonn-Miller MO, Vujanovic AA, et al. Posttraumatic stress disorder and cannabis use in a nationally representative sample. Psychol Addict Behav. 2011;25(3):554-558.
13. Bonn-Miller MO, Vujanovic AA, Drescher KD. Cannabis use among military veterans after residential treatment for posttraumatic stress disorder. Psychol Addict Behav. 2011;25(3):485-491.
14. Bonn-Miller MO, Boden MT, Vujanovic AA, et al. Prospective investigation of the impact of cannabis use disorders on posttraumatic stress disorder symptoms among veterans in residential treatment. Psychol Trauma. 2013;5(2):193-200.
15. Fontana A, Rosenheck R. Treatment-seeking veterans of Iraq and Afghanistan: comparison with veterans of previous wars. J Nerv Ment Dis. 2008;196(7):513-521.
16. Engdahl B, Dikel TN, Eberly R, et al. Comorbidity and course of psychiatric disorders in a community sample of former prisoners of war. Am J Psychiatry. 1998;155(12):1740-1745.
17. Savarese VW, Suvak MK, King LA, et al. Relationships among alcohol use, hyperarousal, and marital abuse and violence in Vietnam veterans. J Trauma Stress. 2001;14(4):717-732.
18. Smith MW, Schnurr PP, Rosenheck RA. Employment outcomes and PTSD symptom severity. Ment Health Serv Res. 2005;7(2):89-101.
19. McFall M, Fontana A, Raskind M, et al. Analysis of violent behavior in Vietnam combat veteran psychiatric inpatients with posttraumatic stress disorder. J Trauma Stress. 1999;12(3):501-517.
20. Fontana A, Rosenheck R, Desai R. Comparison of treatment outcomes for veterans with posttraumatic stress disorder with and without J Psychiatr Res. 2012;46(8):1008-1014.
21. McLellan AT, Luborsky L, Cacciola J, et al. New data from the Addiction Severity Index: reliability and validity in three centers. J Nerv Ment Dis. 1985;173(7):412-423.
22. Fontana A, Rosenheck R. A short form of the Mississippi Scale for measuring change in combat-related PTSD. J Trauma Stress. 1994;7(3):407-414.
23. Kulka RA, Schlenger WE, Fairbank JA, et al. Trauma and the Vietnam War Generation: Report of Findings from the National Vietnam Veterans' Readjustment Study. New York, NY: Brunner/Mazel; 1990.
24. Passie T, Emrich HM, Karst M, et al. Mitigation of post-traumatic stress symptoms by Cannabis resin: A review of the clinical and neurobiological evidence. Drug Test Anal. 2012;4(7-8):649-659.
25. Norman SB, Myers US, Wilkins KC, et al. Review of biological mechanisms and pharmacological treatments of comorbid PTSD and substance use disorder. Neuropharmacology. 2012;62(2):542-551.
26. Greer GR, Grob CS, Halberstadt AL. PTSD symptom reports of patients evaluated for the New Mexico Medical Cannabis Program. J Psychoactive Drugs. 2014;46(1):73-77.
27. Stewart SH, Pihl RO, Conrod PJ, et al. Functional associations among trauma, PTSD, 1998;23(6):797-812.
28. Mulvey EP, Odgers C, Skeem J, et al. Substance use and community violence: A test of the relation at the daily level. J Consult Clin Psychol. 2006;74(4):743-754.
29. Arendt M, Rosenberg R, Fjordback L, et al. Testing the self-medication hypothesis of depression and aggression in cannabisdependent subjects. Psychol Med. 2007;37(7):935-945.
30. Carabellese F, Candelli C, Martinelli D, et al. Cannabis use and violent behaviour: A psychiatric patients cohort study in Southern Italy. Riv Psichiatr. 2013;48(1):43-50.
31. Norström T, Rossow I. Cannabis use and violence: is there a link? Scand J Public Health. 2014;42(4):358-363.
32. Harrison LD, Erickson PG, Adlaf E, et al. The drugs-violence nexus among American and Canadian youth. Subst Use Misuse. 2001;36(14):2065-2086.
33. Friedman AS, Glassman K, Terras BA. Violent behavior as related to use of marijuana and other drugs. J Addict Dis. 2001;20(1):49-72.
34. Barrett EL, Mills KL, Teesson M. Hurt people who hurt people: violence amongst individuals with comorbid substance use disorder and post traumatic stress disorder. Addict Behav. 2011;36(7):721-728.
35. Macdonald S, Erickson P, Wells S, et al. cannabis, and alcohol treatment clients. Addict Behav. 2008;33(1):201-205.
36. Martin SE. The epidemiology of alcoholrelated interpersonal violence. Alcohol Health Res World. 1992;16(3):230-237.
37. Budney AJ, Moore BA, Vandrey RG, et al. The time course and significance of cannabis withdrawal. J Abnorm Psychol. 2003;112(3):393-402.
38. Crippa JA, Zuardi AW, Martín-Santos R, et al. Cannabis and anxiety: A critical review of the evidence. Hum Psychopharmacol. 2009;24(7):515-523.
39. Bergamaschi MM, Queiroz RH, Chagas MH, et al. Cannabidiol reduces the anxiety induced by simulated public speaking in treatment-naïve social phobia patients. Neuropsychopharmacology. 2011;36(6):1219-1226.
40. Campos AC, Ortega Z, Palazuelos J, et al. The anxiolytic effect of cannabidiol on chronically stressed mice depends on hippocampal neurogenesis: involvement of the endocannabinoid system. Int J Neuropsychopharmacol. 2013;16(6):1407-1419.
41. Zuardi AW, Cosme RA, Graeff FG, et al. Effects of ipsapirone and cannabidiol on human experimental anxiety. J Psychopharmacol. 1993;7(suppl):82-88.