Apelin and APLN single nucleotide polymorphisms and combined hypertension and central retinal artery stenosis in a Chinese population

Clinical and Experimental Hypertension

Volumn 37, Issue 4, 2015, Pages 280-287

  Zhu, Pengli ^a   Lin, Fan ^a   Huang, Feng ^a   Huang, Qiuxia ^a   Li, Qiaowei ^a   Gao, Zhonghai ^a   Chen, Falin ^a  

^a FUJIAN MEDICAL UNIVERSITY   (China)

Author keywords

Apelin; APLN single nucleotide polymorphism; Central retinal artery stenosis; Hypertension with CRAE; Primary hypertension

Indexed keywords

APELIN; GLUCOSE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN CHOLESTEROL; APLN PROTEIN, HUMAN; DNA; SIGNAL PEPTIDE;

ADULT; AGE; ALLELE; APELIN BLOOD LEVEL; ARTICLE; CENTRAL RETINA ARTERY OCCLUSION; CHINESE; CHOLESTEROL BLOOD LEVEL; CLINICAL EVALUATION; COMPARATIVE STUDY; CONTROLLED STUDY; DIASTOLIC BLOOD PRESSURE; DISEASE ASSOCIATION; ELISA KIT; ENZYME ACTIVITY; EYE PHOTOGRAPHY; FEMALE; FUNDUS CAMERA; GENE FREQUENCY; GENETIC ANALYSIS; GENOTYPE; GLUCOSE BLOOD LEVEL; HAPLOTYPE; HUMAN; HYPERTENSION; LIPID BLOOD LEVEL; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; PROTEIN BLOOD LEVEL; PROTEIN LOCALIZATION; SEX DIFFERENCE; SINGLE NUCLEOTIDE POLYMORPHISM; SYSTOLIC BLOOD PRESSURE; BLOOD PRESSURE; CHEMICALLY INDUCED; CHINA; COMPLICATION; GENETICS; INCIDENCE; METABOLISM; PHYSIOLOGY; POLYMERASE CHAIN REACTION; RETINAL ARTERY OCCLUSION;

BLOOD PRESSURE; CHINA; DNA; FEMALE; GENOTYPE; HAPLOTYPES; HUMANS; HYPERTENSION; INCIDENCE; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; MIDDLE AGED; POLYMERASE CHAIN REACTION; POLYMORPHISM, SINGLE NUCLEOTIDE; RETINAL ARTERY OCCLUSION;

EID: 84943536006     PISSN: 10641963     EISSN: 15256006     Source Type: Journal    
DOI: 10.3109/10641963.2014.960970     Document Type: Article

References (37)

1. Simonetti GD, Mohaupt MG, Bianchetti MG. Monogenic forms of hypertension. Eur J Pediatr 2012;171:1433-9.
2. Li WW, Niu WQ, Zhang Y, et al. Family-based analysis of apelin and agtrl1 gene polymorphisms with hypertension in Han Chinese. J Hypertens 2009;27:1194-201.
3. Charles CJ. Putative role for apelin in pressure/volume homeostasis and cardiovascular disease. Cardiovasc Hematol Agents Med Chem 2007;5:1-10.
4. Kagiyama S, Fukuhara M, Matsumura K, et al. Central and peripheral cardiovascular actions of apelin in conscious rats. Regul Pept 2005;125:55-9.
5. Seyedabadi M, Goodchild AK, Pilowsky PM. Site-specific effects of apelin-13 in the rat medulla oblongata on arterial pressure and respiration. Auton Neurosci 2002;101:32-8.
6. El Messari S, Iturrioz X, Fassot C, et al. Functional dissociation of apelin receptor signaling and endocytosis: implications for the effects of apelin on arterial blood pressure. J Neurochem 2004;90: 1290-301.
7. Lee DK, Cheng R, Nguyen T, et al. Characterization of apelin, the ligand for the apj receptor. J Neurochem 2000;74:34-41.
8. Tatemoto K, Takayama K, Zou MX, et al. The novel peptide apelin lowers blood pressure via a nitric oxide-dependent mechanism. Regul Pept 2001;99:87-92.
9. Japp AG, Cruden NL, Amer DA, et al. Vascular effects of apelin in vivo in man. J Am Coll Cardiol 2008;52:908-13.
10. Przewlocka-Kosmala M, Kotwica T, Mysiak A, Kosmala W. Reduced circulating apelin in essential hypertension and its association with cardiac dysfunction. J Hypertens 2011;29:971-9.
11. Sonmez A, Celebi G, Erdem G, et al. Plasma apelin and adma levels in patients with essential hypertension. Clin Exp Hypertens 2010;32:179-83.
12. Wong TY, Klein R, Couper DJ, et al. Retinal microvascular abnormalities and incident stroke: the Atherosclerosis Risk in Communities Study. Lancet 2001;358:1134-40.
13. Wong TY, Klein R, Sharrett AR, et al. Retinal microvascular abnormalities and cognitive impairment in middle-aged persons: the Atherosclerosis Risk in the Communities study. Stroke 2002;33: 1487-92.
14. Wong TY, Klein R, Sharrett AR, et al. The prevalence and risk factors of retinal microvascular abnormalities in older people: the Cardiovascular Health Study. Ophthalmology 2003;110: 658-66.
15. Cheung N, Sharrett AR, Klein R, et al. Aortic distensibility and retinal arteriolar narrowing: the Multi-Ethnic Study of Atherosclerosis. Hypertension 2007;50:617-22.
16. Cheung N, Islam FM, Jacobs Jr DR, et al. Arterial compliance and retinal vascular caliber in cerebrovascular disease. Ann Neurol 2007;62:618-24.
17. De Silva DA, Woon FP, Manzano JJ, et al. Behalf of the Multi-Centre Retinal Stroke Study Collaborative Group: the relationship between aortic stiffness and changes in retinal microvessels among Asian ischemic stroke patients. J Hum Hypertens 2012;26:716-22.
18. Vlachopoulos C, Dima I, Aznaouridis K, et al. Acute systemic inflammation increases arterial stiffness and decreases wave reflections in healthy individuals. Circulation 2005;112:2193-200.
19. Feihl F, Liaudet L, Waeber B. The macrocirculation and microcirculation of hypertension. Curr Hypertens Rep 2009;11:182-9.
20. Sun C, Liew G, Wang JJ, et al. Retinal vascular caliber, blood pressure, and cardiovascular risk factors in an Asian population: the Singapore Malay Eye Study. Invest Ophthalmol Vis Sci 2008;49: 1784-90.
21. Kawasaki R, Wang JJ, Rochtchina E, et al. Cardiovascular risk factors and retinal microvascular signs in an adult Japanese population: the funagata study. Ophthalmology 2006; 113:1378-84.
22. Wong TY, Islam FM, Klein R, et al. Retinal vascular caliber, cardiovascular risk factors, and inflammation: the multi-ethnic study of atherosclerosis (MESA). Invest Ophthalmol Vis Sci 2006; 47:2341-50.
23. Ikram MK, de Jong FJ, Bos MJ, et al. Retinal vessel diameters and risk of stroke: the Rotterdam study. Neurology 2006;66: 1339-43.
24. Niu W, Wu S, Zhang Y, et al. Validation of genetic association in apelin-agtrl1 system with hypertension in a larger Han Chinese population. J Hypertens 2010;28:1854-61.
25. Chobanian AV, Bakris GL, Black HR, et al. National Heart, Lung, and Blood Institute Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure; National High Blood Pressure Education Program Coordinating Committee. The seventh report of the joint national committee on prevention, detection, evaluation, and treatment of high blood pressure: the jnc 7 report. JAMA 2003;289:2560-72.
26. American Diabetes A. Standards of medical care in diabetes - 2011. Diabetes Care 2011;34:S11-61.
27. Cheung CY, Zheng Y, Hsu W, et al. Retinal vascular tortuosity, blood pressure, and cardiovascular risk factors. Ophthalmology 2011;118:812-18.
28. Cheung CY, Tay WT, Mitchell P, et al. Quantitative and qualitative retinal microvascular characteristics and blood pressure. J Hypertens 2011;29:1380-91.
29. Wong TY, Hubbard LD, Klein R, et al. Retinal microvascular abnormalities and blood pressure in older people: the cardiovascular health study. Br J Ophthalmol 2002;86:1007-13.
30. de Kok JB, Wiegerinck ET, Giesendorf BA, Swinkels DW. Rapid genotyping of single nucleotide polymorphisms using novel minor groove binding DNA oligonucleotides (mgb probes). Hum Mutat 2002;19:554-9.
31. Hashimoto T, Kihara M, Ishida J, et al. Apelin stimulates myosin light chain phosphorylation in vascular smooth muscle cells. Arterioscler Thromb Vasc Biol 2006;26:1267-72.
32. Tatemoto K, Takayama K, Zou MX, et al. The novel peptide apelin lowers blood pressure via a nitric oxide-dependent mechanism. Regul Pept 2001;99:87-92.
33. Kidoya H, Ueno M, Yamada Y, et al. Spatial and temporal role of the Apelin-APJ system in the caliber size regulation of blood vessels during angiogenesis. EMBO J 2008;27:522-34.
34. Kasai A, Shintani N, Oda M, et al. Apelin is a novel angiogenic factor in retinal endothelial cells. Biochem Biophys Res Commun 2004;325:395-400.
35. Zhang R, Lu J, Hu C, et al. Associations of common variants at APLN and hypertension in Chinese subjects with and without diabetes. Exp Diabetes Res 2012;17:1-6.
36. Wong TY, Kamineni A, Klein R, et al. Quantitative retinal venular caliber and risk of cardiovascular disease in older persons: the cardiovascular health study. Arch Intern Med 2006;166: 2388-94.
37. Rosman M, Zheng Y, Lamoureux E, et al. Review of key findings from the Singapore Malay Eye Study (simes-1). Singapore Med J 2012;53:82-7.