Myocardial inflammation in experimental acute right ventricular failure: Effects of prostacyclin therapy

Journal of Heart and Lung Transplantation

Volumn 34, Issue 10, 2015, Pages 1334-1345

  Dewachter, Céline ^a   Belhaj, Asmae ^a,b,c   Rondelet, Benoit ^a,b,c   Vercruyssen, Marie ^a   Schraufnagel, Dean P ^a   Remmelink, Myriam ^b   Brimioulle, Serge ^a,b   Kerbaul, François ^a,d   Naeije, Robert ^a   Dewachter, Laurence ^a  

^a UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

^b ERASME HOSPITAL   (Belgium)

^c UNIVERSITY HOSPITAL OF MONT GODINNE   (Belgium)

^d TIMONE HOSPITAL   (France)

Author keywords

acute right heart syndrome; inflammation; prostacyclin; pulmonary hypertension; Right ventricular failure; ventriculoarterial coupling

Indexed keywords

HEME OXYGENASE 1; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 1; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 10; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 33; INTERLEUKIN 6; MONOCYTE CHEMOTACTIC PROTEIN 1; PROSTACYCLIN; PROSTACYCLIN SYNTHASE; SYNAPSIN I; VASCULAR CELL ADHESION MOLECULE 1; ANTIHYPERTENSIVE AGENT; CELL ADHESION MOLECULE; CHEMOKINE;

ACUTE RIGHT VENTRICULAR FAILURE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN BINDING; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; GENE EXPRESSION; HEART LEFT VENTRICLE; HEART OUTPUT; HEART RIGHT VENTRICLE FAILURE; IMMUNOHISTOCHEMISTRY; LUNG ARTERY BANDING; MACROPHAGE; MONGREL DOG; MYOCARDITIS; NEUTROPHIL; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; ANIMAL; DISEASE MODEL; DOG; HEART RIGHT VENTRICLE FUNCTION; METABOLISM;

ANIMALS; ANTIHYPERTENSIVE AGENTS; CELL ADHESION MOLECULES; CHEMOKINES; DISEASE MODELS, ANIMAL; DOGS; EPOPROSTENOL; MYOCARDITIS; VENTRICULAR DYSFUNCTION, RIGHT;

EID: 84943365030     PISSN: 10532498     EISSN: 15573117     Source Type: Journal    
DOI: 10.1016/j.healun.2015.05.004     Document Type: Article

References (47)

1. C.R. Greyson Pathophysiology of right ventricular failure Crit Care Med 36 1 Suppl 2008 S57 S65
2. H.J. Bogaard, K. Abe, A. Vonk Noordegraaf, and N.F. Voelkel The right ventricle under pressure: cellular and molecular mechanisms of right-heart failure in pulmonary hypertension Chest 135 2009 794 804
3. N.S. Hill, K.R. Roberts, and I.R. Preston Postoperative pulmonary hypertension: etiology and treatment of a dangerous complication Respir Care 54 2009 958 968
4. P.F. Fedullo, W.R. Auger, K.M. Kerr, and L.J. Rubin Chronic thromboembolic pulmonary hypertension N Engl J Med 345 2001 1465 1472
5. M.K. Pasque, E.P. Trulock, L.R. Kaiser, and J.D. Cooper Single-lung transplantation for pulmonary hypertension. Three-month hemodynamic follow-up Circulation 84 1991 2275 2279
6. F. Kerbaul, S. Brimioulle, B. Rondelet, C. Dewachter, I. Hubloue, and R. Naeije How prostacyclin improves cardiac output in right heart failure in conjunction with pulmonary hypertension Am J Respir Crit Care Med 175 2007 846 850
7. C. Dewachter, L. Dewachter, B. Rondelet, and et al. Activation of apoptotic pathways in experimental acute afterload-induced right ventricular failure Crit Care Med 38 2010 1405 1413
8. B. Rondelet, C. Dewachter, F. Kerbaul, and et al. Prolonged overcirculation-induced pulmonary arterial hypertension as a cause of right ventricular failure Eur Heart J 33 2012 1017 1026
9. N. Galie, M.M. Hoeper, M. Humbert, and et al. Guidelines for the diagnosis and treatment of pulmonary hypertension Eur Respir J 34 2009 1219 1263
10. D.B. Badesch, V.V. McLaughlin, M. Delcroix, and et al. Prostanoid therapy for pulmonary arterial hypertension J Am Coll Cardiol 43 12 Suppl S 2004 56 61S
11. R.J. Barst, L.J. Rubin, W.A. Long, and et al. A comparison of continuous intravenous epoprostenol (prostacyclin) with conventional therapy for primary pulmonary hypertension. The Primary Pulmonary Hypertension Study Group N Engl J Med 334 1996 296 302
12. S. Rich, and V.V. McLaughlin The effects of chronic prostacyclin therapy on cardiac output and symptoms in primary pulmonary hypertension J Am Coll Cardiol 34 1999 1184 1187
13. Z. Jaffar, M.E. Ferrini, M.C. Buford, G.A. Fitzgerald, and K. Roberts Prostaglandin I2-IP signaling blocks allergic pulmonary inflammation by preventing recruitment of CD4+ Th2 cells into the airways in a mouse model of asthma J Immunol 179 2007 6193 6203
14. W. Zhou, T.S. Blackwell, K. Goleniewska, and et al. Prostaglandin I2 analogs inhibit Th1 and Th2 effector cytokine production by CD4 T cells J Leukoc Biol 81 2007 809 817
15. S. Brimioulle, P. Wauthy, P. Ewalenko, and et al. Single-beat estimation of right ventricular end-systolic pressure-volume relationship Am J Physiol Heart Circ Physiol 284 2003 H1625 H1630
16. M.P. Begieneman, F.R. van de Goot, I.A. van der Bilt, and et al. Pulmonary embolism causes endomyocarditis in the human heart Heart 94 2008 450 456
17. M. Bujak, and N.G. Frangogiannis The role of IL-1 in the pathogenesis of heart disease Arch Immunol Ther Exp (Warsz) 57 2009 165 176
18. U. Hofmann, S. Heuer, K. Meder, and et al. The proinflammatory cytokines TNF-alpha and IL-1 beta impair economy of contraction in human myocardium Cytokine 39 2007 157 162
19. S. Sanada, D. Hakuno, L.J. Higgins, E.R. Schreiter, A.N. McKenzie, and R.T. Lee IL-33 and ST2 comprise a critical biomechanically induced and cardioprotective signaling system J Clin Invest 117 2007 1538 1549
20. Y.H. Zhang, J.X. Lin, and J. Vilcek Interleukin-6 induction by tumor necrosis factor and interleukin-1 in human fibroblasts involves activation of a nuclear factor binding to a kappa B-like sequence Mol Cell Biol 10 1990 3818 3823
21. X.W. Yu, M.Y. Liu, R.H. Kennedy, and S.J. Liu Both cGMP and peroxynitrite mediate chronic interleukin-6-induced negative inotropy in adult rat ventricular myocytes J Physiol 566 2005 341 353
22. D.L. Maass, J. White, and J.W. Horton IL-1beta and IL-6 act synergistically with TNF-alpha to alter cardiac contractile function after burn trauma Shock 18 2002 360 366
23. S.D. Anker, and S. von Haehling Inflammatory mediators in chronic heart failure: an overview Heart 90 2004 464 470
24. Y. Seta, K. Shan, B. Bozkurt, H. Oral, and D.L. Mann Basic mechanisms in heart failure: the cytokine hypothesis J Card Fail 2 1996 243 249
25. M. Humbert, G. Monti, F. Brenot, and et al. Increased interleukin-1 and interleukin-6 serum concentrations in severe primary pulmonary hypertension Am J Respir Crit Care Med 151 1995 1628 1631
26. E. Soon, A.M. Holmes, C.M. Treacy, and et al. Elevated levels of inflammatory cytokines predict survival in idiopathic and familial pulmonary arterial hypertension Circulation 122 2010 920 927
27. S. Adamopoulos, J.T. Parissis, and D.T. Kremastinos A glossary of circulating cytokines in chronic heart failure Eur J Heart Fail 3 2001 517 526
28. L. Zhou, A. Azfer, J. Niu, and et al. Monocyte chemoattractant protein-1 induces a novel transcription factor that causes cardiac myocyte apoptosis and ventricular dysfunction Circ Res 98 2006 1177 1185
29. P.E. Kolattukudy, T. Quach, S. Bergese, and et al. Myocarditis induced by targeted expression of the MCP-1 gene in murine cardiac muscle Am J Pathol 152 1998 101 111
30. B.J. Wrigley, G.Y. Lip, and E. Shantsila The role of monocytes and inflammation in the pathophysiology of heart failure Eur J Heart Fail 13 2011 1161 1171
31. M. Constantin, A.J. Choi, S.M. Cloonan, and S.W. Ryter Therapeutic potential of heme oxygenase-1/carbon monoxide in lung disease Int J Hypertens 2012 2012 859235
32. S.F. Yet, M.A. Perrella, M.D. Layne, and et al. Hypoxia induces severe right ventricular dilatation and infarction in heme oxygenase-1 null mice J Clin Invest 103 1999 R23 R29
33. D. Katayose, S. Isoyama, H. Fujita, and S. Shibahara Separate regulation of heme oxygenase and heat shock protein 70 mRNA expression in the rat heart by hemodynamic stress Biochem Biophys Res Commun 191 1993 587 594
34. H.J. Bogaard, R. Natarajan, S.C. Henderson, and et al. Chronic pulmonary artery pressure elevation is insufficient to explain right heart failure Circulation 120 2009 1951 1960
35. K. Youker, C.W. Smith, D.C. Anderson, and et al. Neutrophil adherence to isolated adult cardiac myocytes. Induction by cardiac lymph collected during ischemia and reperfusion J Clin Invest 89 1992 602 609
36. H. Kai, F. Kuwahara, K. Tokuda, and T. Imaizumi Diastolic dysfunction in hypertensive hearts: roles of perivascular inflammation and reactive myocardial fibrosis Hypertens Res 28 2005 483 490
37. J.A. Watts, J. Zagorski, M.A. Gellar, B.G. Stevinson, and J.A. Kline Cardiac inflammation contributes to right ventricular dysfunction following experimental pulmonary embolism in rats J Mol Cell Cardiol 41 2006 296 307
38. J. Zagorski, N. Sanapareddy, M.A. Gellar, J.A. Kline, and J.A. Watts Transcriptional profile of right ventricular tissue during acute pulmonary embolism in rats Physiol Genomics 34 2008 101 111
39. M.E. Campian, M. Hardziyenka, K. de Bruin, and et al. Early inflammatory response during the development of right ventricular heart failure in a rat model Eur J Heart Fail 12 2010 653 658
40. S.Y. Ho, and P. Nihoyannopoulos Anatomy, echocardiography, and normal right ventricular dimensions Heart 92 Suppl 1 2006 i2 13
41. M. Hardziyenka, M.E. Campian, A.O. Verkerk, and et al. Electrophysiologic remodeling of the left ventricle in pressure overload-induced right ventricular failure J Am Coll Cardiol 59 2012 2193 2202
42. W. Zhou, K. Hashimoto, K. Goleniewska, and et al. Prostaglandin I2 analogs inhibit proinflammatory cytokine production and T cell stimulatory function of dendritic cells J Immunol 178 2007 702 710
43. D. Strassheim, S.R. Riddle, D.L. Burke, M.W. Geraci, and K.R. Stenmark Prostacyclin inhibits IFN-gamma-stimulated cytokine expression by reduced recruitment of CBP/p300 to STAT1 in a SOCS-1-independent manner J Immunol 183 2009 6981 6988
44. K. Yamauchi-Takihara, and T. Kishimoto Cytokines and their receptors in cardiovascular diseases - role of gp130 signalling pathway in cardiac myocyte growth and maintenance Int J Exp Pathol 81 2000 1 16
45. K. Goya, M. Otsuki, X. Xu, and S. Kasayama Effects of the prostaglandin I2 analogue, beraprost sodium, on vascular cell adhesion molecule-1 expression in human vascular endothelial cells and circulating vascular cell adhesion molecule-1 level in patients with type 2?diabetes mellitus Metabolism 52 2003 192 198
46. J. Gomez-Arroyo, M. Sakagami, A.A. Syed, and et al. Iloprost reverses established fibrosis in experimental right ventricular failure Eur Respir J 45 2015 449 462
47. C. Greyson, Y. Xu, J. Cohen, and G.G. Schwartz Right ventricular dysfunctiosn persists following brief right ventricular pressure overload Cardiovasc Res 34 1997 281 288