Methods for reducing sepsis mortality in emergency departments and inpatient units

Joint Commission Journal on Quality and Patient Safety

Volumn 41, Issue 5, 2015, Pages 205-211

  Doerfler, Martin E ^a,b   D'Angelo, John ^c   Jacobsen, Diane ^d   Jarrett, Mark P ^b   Kabcenell, Andrea I ^e   Masick, Kevin D ^e   Parmentier, Darlene ^f   Nelson, Karen L ^e   Stier, Lori ^e  

^a Clinical Strategy and Development   (United States)

^b Northwell Health   (United States)

^c Emergency Medicine Service Line   (United States)

^d INSTITUTE FOR HEALTHCARE IMPROVEMENT   (United States)

^e North Shore LIJ Health System   (United States)

^f Northwell Health   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EMERGENCY HEALTH SERVICE; HOSPITAL PATIENT; HUMAN; INTENSIVE CARE; MORTALITY; ORGANIZATION AND MANAGEMENT; PRACTICE GUIDELINE; SEPSIS; TOTAL QUALITY MANAGEMENT; UNITED STATES;

CRITICAL CARE; EMERGENCY SERVICE, HOSPITAL; HUMANS; INPATIENTS; PRACTICE GUIDELINES AS TOPIC; QUALITY IMPROVEMENT; SEPSIS; UNITED STATES;

EID: 84943362817     PISSN: 15537250     EISSN: None     Source Type: Journal    
DOI: 10.1016/s1553-7250(15)41027-x     Document Type: Article

References (30)

1. Angus D, et al. Epidemiology of severe sepsis in the United States: Analysis of incidence, outcome, and costs of care. Crit Care Med. 2001;29(7):1303-1310.
2. Skrupky LP, Kerby PW, Hotchkiss RS. Advances in the management of sepsis and the understanding of key immunologic defects. Anesthesiology. 2011;115(6):1349-1362.
3. Czura CJ. Merinoff Symposium 2010: Sepsis - an international call to action. Mol Med. 2010;16(5-6):157-158.
4. Global Sepsis Alliance. Home page. Accessed Apr 1, 2015. http://globalsepsisalliance.com/.
5. Dellinger RP, et al.; Surviving Sepsis Campaign Management Guidelines Committee. Surviving Sepsis Campaign guidelines for management of severe sepsis and septic shock. Crit Care Med. 2004;32(3):858-873.
6. Rivers E, et al. Early goal-directed therapy in the treatment of severe sepsis and septic shock. N Engl J Med. 2001Nov 8;345(19):1368-1377.
7. Dellinger RP, et al. Surviving Sepsis Campaign: International guidelines for management of severe sepsis and septic shock: 2008. Crit Care Med. 2008;36(1):296-327.
8. Dellinger RP, et al. Surviving Sepsis Campaign: International guidelines for management of severe sepsis and septic shock, 2012. Intensive Care Med. 2013;39(2):165-228.
9. Hoo WE, et al. Successes and lessons learned implementing the sepsis bundle. J Healthc Qual. 2009;31(4):9-15.
10. Focht A, Jones AE, Lowe TJ. Early goal-directed therapy: Improving mortality and morbidity of sepsis in the emergency department. Jt Comm J Qual Patient Saf. 2009;35(4):186-191.
11. Institute for Healthcare Improvement (IHI): The Breakthrough Series: IHI's Collaborative Model for Achieving Breakthrough Improvement. IHI Innovation Series white paper. Cambridge, MA: IHI, 2003.
12. Centers for Medicare & Medicaid Services, Center for Medicare and Medicaid Innovation Learning and Diffusion Group. Defining and Using Aims and Drivers for Improvement: A How-to Guide. Jan 2013. Accessed Apr 1, 2015. http://innovation.cms.gov/files/x/hciatwoaimsdrvrs.pdf.
13. Bone, RC, et al. Sepsis syndrome: A valid clinical entity Methylprednisolone Severe Sepsis Study Group. Crit Care Med. 1989;17(5):389-393.
14. Kumar A, et al. Duration of hypotension before initiation of effective antimicrobial therapy is the critical determinant of survival in human septic shock. Crit Care Med. 2006;34(6):1589-1596.
15. Gaieski DF, et al. Impact of time to antibiotics on survival in patients with severe sepsis or septic shock in whom early goal-directed therapy was initiated in the emergency department. Crit Care Med. 2010;38(4):1045-1053.
16. Ferrer R, et al. Empiric antibiotic treatment reduces mortality in severe sepsis and septic shock from the first hour: Results from a guideline-based performance improvement program. Crit Care Med. 2014;42(8):1749-1755.
17. Agency for Healthcare Research and Quality. TeamSTEPPS™: Strategies and Tools to Enhance Performance and Patient Safety. King HB, et al. 2007. Accessed Apr 1, 2015. http://www.ahrq.gov/professionals/quality-patient-safety/patient-safety-resources/resources/advances-in-patient-safety-2/vol3/Advances-King-1.pdf.
18. Thomas L, Galla C. Building a culture of safety through team training and engagement. BMJ Qual Saf. 2013;22(5):425-434.
19. Subbe CP, et al. Validation of a modified Early Warning Score in medical admissions. QJM. 2001;94(10):521-526.
20. Morgan RJM, Williams F, Wright MM. An early warning scoring system for detecting developing critical illness. Clin Intensive Care. 1997;8(2):100.
21. Subbe CP, et al. Effect of introducing the Modified Early Warning score on clinical outcomes, cardio-pulmonary arrests and intensive care utilisation in acute medical admissions. Anaesthesia. 2003;58(8):797-802.
22. Maccarone N, et al. Impact of a systematic MEWS introduction on preoperative and postoperative evaluation in urgent/emergency surgery. Crit Care. 2010;14(Suppl 1):P255.
23. Gardner-Thorpe J, et al. The value of Modified Early Warning Score (MEWS) in surgical in-patients: A prospective observational study. Ann R Coll Surg Engl. 2006;88(6):571-575.
24. Friedman MI, Doerfler M, Tamuz M. Safety hub: Research and role of a simulation center in a system-wide initiative to reduce sepsis. In Gallo K, Smith LG, editors: Building a Culture of Patient Safety Through Simulation: An Interprofessional Model. New York City: Springer, 2015, 45-52.
25. Levy, MM, et al. Sepsis change bundles: Converting guidelines into meaningful change in behavior and clinical outcome. Crit Care Med. 2004;32(11 Suppl):S595-597.
26. Miller RR 3rd, et al. Multicenter implementation of a severe sepsis and septic shock treatment bundle. Am J Respir Crit Care Med. 2013 Jul 1;188(1):77-82.
27. New York State Department of Health. Sepsis Regulations: Guidance Document 405.4 (a)(4). (Updated: Jul 2012.) Accessed Apr 1, 2015. https://www.health.ny.gov/regulations/public-health-law/section/405/.
28. New York State Department of Health. Council Meeting Document.Accessed Apr 1, 2015. https://www.health.ny.gov/facilities/public-health-and-health-planning-council/meetings/2013-02-07/docs/13-01.pdf.
29. Dwyer J. An infection, unnoticed, turns unstoppable. New York Times Jul 11, 2012. Accessed Apr 1, 2015. http://www.nytimes.com/2012/07/12/nyregion/in-rory-stauntons-fight-for-his-life-signs-that-went-unheeded.html?-r=0.
30. Rory Staunton Foundation. Home page. Accessed Apr 1, 2015. http://rorystaunton.com/.