Present-day hospital readmissions after left ventricular assist device implantation: A large single-center study

Texas Heart Institute Journal

Volumn 42, Issue 5, 2015, Pages 419-429

  Hernandez, Ruben E ^a,c   Singh, Steve K ^a   Hoang, Dale T ^a,b   Ali, Syed W ^a   Elayda, MacArthur A ^a   Mallidi, Hari R ^a   Frazier, O H ^a   Meyers, Deborah E ^a  

^a TEXAS HEART INSTITUTE   (United States)

^b Department of Obstetrics Gynecology   (United States)

^c ST JOHN S EPISCOPAL HOSPITAL   (United States)

Author keywords

Comorbidity; Diabetes complications epidemiology mortality surgery; Heart failure therapy; Heart assist devices; Hospital readmission; Hospitalization statistics and numerical data; Left ventricular assist device; Patient readmission statistics and numerical data; Retrospective studies; Surgical wound infections; Thrombosis; Treatment outcome

Indexed keywords

ADULT; ANTICOAGULATION; ARTICLE; BLEEDING; COMORBIDITY; DIABETES MELLITUS; FEMALE; HEART FAILURE; HOSPITAL READMISSION; HUMAN; IMPLANTATION; LEFT VENTRICULAR ASSIST DEVICE; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; SURVIVAL; THROMBOSIS; ADVERSE EFFECTS; AGED; HEART ASSIST DEVICE; HEART LEFT VENTRICLE FUNCTION; HEART TRANSPLANTATION; HOSPITAL ADMISSION; KAPLAN MEIER METHOD; METABOLISM; MULTIVARIATE ANALYSIS; ODDS RATIO; PATHOPHYSIOLOGY; PATIENT TRANSPORT; PROSTHESIS DESIGN; RETROSPECTIVE STUDY; RISK FACTOR; SEVERITY OF ILLNESS INDEX; TEXAS; TIME FACTOR; TREATMENT OUTCOME;

ADULT; AGED; COMORBIDITY; FEMALE; HEART FAILURE; HEART TRANSPLANTATION; HEART-ASSIST DEVICES; HUMANS; KAPLAN-MEIER ESTIMATE; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; ODDS RATIO; PATIENT READMISSION; PROSTHESIS DESIGN; RETROSPECTIVE STUDIES; RISK FACTORS; SEVERITY OF ILLNESS INDEX; TEXAS; TIME FACTORS; TRANSPORTATION OF PATIENTS; TREATMENT OUTCOME; VENTRICULAR FUNCTION, LEFT; WAITING LISTS;

EID: 84943237343     PISSN: 07302347     EISSN: 15266702     Source Type: Journal    
DOI: 10.14503/THIJ-14-4971     Document Type: Article

References (40)

1. Miller LW, Pagani FD, Russell SD, John R, Boyle AJ, Aaronson KD, et al. Use of a continuous-flow device in patients awaiting heart transplantation. N Engl J Med 2007;357(9): 885-96.
2. Slaughter MS, Rogers JG, Milano CA, Russell SD, Conte JV, Feldman D, et al. Advanced heart failure treated with continuous-flow left ventricular assist device. N Engl J Med 2009; 361(23):2241-51.
3. Aaronson KD, Slaughter MS, Miller LW, McGee EC, Cotts WG, Acker MA, et al. Use of an intrapericardial, continuousflow, centrifugal pump in patients awaiting heart transplantation. Circulation 2012;125(25):3191-200.
4. Rogers JG, Aaronson KD, Boyle AJ, Russell SD, Milano CA, Pagani FD, et al. Continuous flow left ventricular assist device improves functional capacity and quality of life of advanced heart failure patients. J Am Coll Cardiol 2010;55(17):1826-34.
5. John R, Naka Y, Smedira NG, Starling R, Jorde U, Eckman P, et al. Continuous flow left ventricular assist device outcomes in commercial use compared with the prior clinical trial. Ann Thorac Surg 2011;92(4):1406-13.
6. Terracciano CM, Miller LW, Yacoub MH. Contemporary use of ventricular assist devices. Annu Rev Med 2010;61:255-70.
7. Kamdar F, Boyle A, Liao K, Colvin-Adams M, Joyce L, John R. Effects of centrifugal, axial, and pulsatile left ventricular assist device support on end-organ function in heart failure patients. J Heart Lung Transplant 2009;28(4):352-9.
8. Adamson RM, Stahovich M, Chillcott S, Baradarian S, Chammas J, Jaski B, et al. Clinical strategies and outcomes in advanced heart failure patients older than 70 years of age receiving the HeartMate II left ventricular assist device: a community hospital experience. J Am Coll Cardiol 2011;57(25): 2487-95.
9. Kirklin JK, Naftel DC, Kormos RL, Stevenson LW, Pagani FD, Miller MA, et al. The Fourth INTERMACS Annual Report: 4,000 implants and counting. J Heart Lung Transplant 2012;31(2):117-26.
10. Moazami N, Fukamachi K, Kobayashi M, Smedira NG, Hoercher KJ, Massiello A, et al. Axial and centrifugal continuousflow rotary pumps: a translation from pump mechanics to clinical practice. J Heart Lung Transplant 2013;32(1):1-11.
11. Kirklin JK, Naftel DC, Kormos RL, Stevenson LW, Pagani FD, Miller MA, et al. Fifth INTERMACS annual report: risk factor analysis from more than 6,000 mechanical circulatory support patients. J Heart Lung Transplant 2013;32(2):141-56.
12. Russell SD, Rogers JG, Milano CA, Dyke DB, Pagani FD, Aranda JM, et al. Renal and hepatic function improve in advanced heart failure patients during continuous-flow support with the HeartMate II left ventricular assist device. Circulation 2009;120(23):2352-7.
13. Sandner SE, Zimpfer D, Zrunek P, Rajek A, Schima H, Dunkler D, et al. Renal function and outcome after continuous flow left ventricular assist device implantation. Ann Thorac Surg 2009;87(4):1072-8.
14. Mehra MR, Stewart GC, Uber PA. The vexing problem of thrombosis in long-term mechanical circulatory support. J Heart Lung Transplant 2014;33(1):1-11.
15. Slaughter MS, Pagani FD, Rogers JG, Miller LW, Sun B, Russell SD, et al. Clinical management of continuous-flow left ventricular assist devices in advanced heart failure. J Heart Lung Transplant 2010;29(4 Suppl):S1-39.
16. Metcalfe C, Thompson SG, Cowie MR, Sharples LD. The use of hospital admission data as a measure of outcome in clinical studies of heart failure. Eur Heart J 2003;24(1):105-12.
17. Brush S, Budge D, Alharethi R, McCormick AJ, MacPherson JE, Reid BB, et al. End-of-life decision making and implementation in recipients of a destination left ventricular assist device. J Heart Lung Transplant 2010;29(12):1337-41.
18. Setoguchi S, Stevenson LW, Schneeweiss S. Repeated hospitalizations predict mortality in the community population with heart failure. Am Heart J 2007;154(2):260-6.
19. Alba AC, Braga J, Gewarges M, Walter SD, Guyatt GH, Ross HJ. Predictors of mortality in patients with an implantable cardiac defibrillator: a systematic review and meta-analysis. Can J Cardiol 2013;29(12):1729-40.
20. Chamberlain AM, McNallan SM, Dunlay SM, Spertus JA, Redfield MM, Moser DK, et al. Physical health status measures predict all-cause mortality in patients with heart failure. Circ Heart Fail 2013;6(4):669-75.
21. Bernheim SM, Grady JN, Lin Z, Wang Y, Wang Y, Savage SV, et al. National patterns of risk-standardized mortality and readmission for acute myocardial infarction and heart failure. Update on publicly reported outcomes measures based on the 2010 release. Circ Cardiovasc Qual Outcomes 2010;3(5): 459-67.
22. Krumholz HM, Merrill AR, Schone EM, Schreiner GC, Chen J, Bradley EH, et al. Patterns of hospital performance in acute myocardial infarction and heart failure 30-day mortality and readmission. Circ Cardiovasc Qual Outcomes 2009;2 (5):407-13.
23. Bradley EH, Curry L, Horwitz LI, Sipsma H, Wang Y, Walsh MN, et al. Hospital strategies associated with 30-day readmission rates for patients with heart failure. Circ Cardiovasc Qual Outcomes 2013;6(4):444-50.
24. Rogers JG, Bostic RR, Tong KB, Adamson R, Russo M, Slaughter MS. Cost-effectiveness analysis of continuous-flow left ventricular assist devices as destination therapy. Circ Heart Fail 2012;5(1):10-6.
25. Smedira NG, Hoercher KJ, Lima B, Mountis MM, Starling RC, Thuita L, et al. Unplanned hospital readmissions after HeartMate II implantation: frequency, risk factors, and impact on resource use and survival. JACC Heart Fail 2013;1 (1):31-9.
26. Forest SJ, Bello R, Friedmann P, Casazza D, Nucci C, Shin JJ, et al. Readmissions after ventricular assist device: etiologies, patterns, and days out of hospital. Ann Thorac Surg 2013;95 (4):1276-81.
27. Hasin T, Marmor Y, Kremers W, Topilsky Y, Severson CJ, Schirger JA, et al. Readmissions after implantation of axial flow left ventricular assist device. J Am Coll Cardiol 2013;61 (2):153-63.
28. Jennings DL, Wagner JL, To L, Nemerovski CW, Kalus JS, Morgan JA, Lanfear DE. Epidemiology and outcomes associated with anemia during long-term support with continuousflow left ventricular assist devices. J Card Fail 2014;20(6): 387-91.
29. Carson JL, Scholz PM, Chen AY, Peterson ED, Gold J, Schneider SH. Diabetes mellitus increases short-term mortality and morbidity in patients undergoing coronary artery bypass graft surgery. J Am Coll Cardiol 2002;40(3):418-23.
30. Alserius T, Hammar N, Nordqvist T, Ivert T. Improved survival after coronary artery bypass grafting has not influenced the mortality disadvantage in patients with diabetes mellitus. J Thorac Cardiovasc Surg 2009;138(5):1115-22.
31. Hoffman DM, Dimitrova KR, Decastro H, Friedmann P, Geller CM, Ko W, Tranbaugh RF. Improving long term outcome for diabetic patients undergoing surgical revascularization by use of the radial artery conduit: a propensity matched study. J Cardiothorac Surg 2013;8:27.
32. Halkos ME, Puskas JD, Lattouf OM, Kilgo P, Kerendi F, Song HK, et al. Elevated preoperative hemoglobin A1c level is predictive of adverse events after coronary artery bypass surgery. J Thorac Cardiovasc Surg 2008;136(3):631-40.
33. Lola I, Levidiotou S, Petrou A, Arnaoutoglou H, Apostolakis E, Papadopoulos GS. Are there independent predisposing factors for postoperative infections following open heart surgery? J Cardiothorac Surg 2011;6:151.
34. Hudson CC, Welsby IJ, Phillips-Bute B, Mathew JP, Lutz A, Chad-Hughes G, et al. Glycosylated hemoglobin levels and outcome in non-diabetic cardiac surgery patients. Can J Anaesth 2010;57(6):565-72.
35. Tennyson C, Lee R, Attia R. Is there a role for HbA1c in predicting mortality and morbidity outcomes after coronary artery bypass graft surgery? Interact Cardiovasc Thorac Surg 2013;17(6):1000-8.
36. Pagani FD, Miller LW, Russell SD, Aaronson KD, John R, Boyle AJ, et al. Extended mechanical circulatory support with a continuous-flow rotary left ventricular assist device. J Am Coll Cardiol 2009;54(4):312-21.
37. Khazanie P, Hammill BG, Patel CB, Eapen ZJ, Peterson ED, Rogers JG, et al. Trends in the use and outcomes of ventricular assist devices among Medicare beneficiaries, 2006 through 2011. J Am Coll Cardiol 2014;63(14):1395-404.
38. Gordon RJ, Quagliarello B, Lowy FD. Ventricular assist device-related infections. Lancet Infect Dis 2006;6(7):426-37.
39. Holman WL, Pamboukian SV, McGiffin DC, Tallaj JA, Cadeiras M, Kirklin JK. Device related infections: are we making progress? J Card Surg 2010;25(4):478-83.
40. Bunte MC, Blackstone EH, Thuita L, Fowler J, Joseph L, Ozaki A, et al. Major bleeding during HeartMate II support. J Am Coll Cardiol 2013;62(23):2188-96.