메뉴 건너뛰기




Volumn 10, Issue 4, 2015, Pages 239-245

Formulation and pharmacology of long-acting cabotegravir

Author keywords

Cabotegravir; Formulation; Long Acting; Nanosuspension; Pharmacokinetics

Indexed keywords

CABOTEGRAVIR; GLUCURONOSYLTRANSFERASE 1A1; LONG ACTING DRUG; ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; PYRIDONE DERIVATIVE;

EID: 84943154337     PISSN: 1746630X     EISSN: 17466318     Source Type: Journal    
DOI: 10.1097/COH.0000000000000168     Document Type: Review
Times cited : (144)

References (22)
  • 1
    • 84943188005 scopus 로고    scopus 로고
    • Panel on Antiretroviral Guidelines for Adults and Adolescents. Guidelines for the use of antiretroviral agents in HIV-1-infected adults and adolescents. Department of Health and Human Services 2014 [Accessed 8 December 2014]
    • Panel on Antiretroviral Guidelines for Adults and Adolescents. Guidelines for the use of antiretroviral agents in HIV-1-infected adults and adolescents. Department of Health and Human Services 2014 http://aidsinfo.nih.gov/ContentFiles/AdultandAdolescentGL.pdf. [Accessed 8 December 2014]
  • 2
    • 0034604276 scopus 로고    scopus 로고
    • Adherence to protease inhibitor therapy and outcomes in patients with HIV infection
    • Paterson DL, Swindells S, Mohr J, et al. Adherence to protease inhibitor therapy and outcomes in patients with HIV infection. Ann Intern Med 2000; 133:21-30.
    • (2000) Ann Intern Med , vol.133 , pp. 21-30
    • Paterson, D.L.1    Swindells, S.2    Mohr, J.3
  • 3
    • 80051633217 scopus 로고    scopus 로고
    • Prevention of HIV-1 infection with early antiretroviral therapy
    • Cohen MS, Chen YQ, McCauley M, et al. Prevention of HIV-1 infection with early antiretroviral therapy. N Engl J Med 2011; 365:493-505.
    • (2011) N Engl J Med , vol.365 , pp. 493-505
    • Cohen, M.S.1    Chen, Y.Q.2    McCauley, M.3
  • 5
    • 84943164104 scopus 로고    scopus 로고
    • ClinicalTrials.gov. A phase IIb study to evaluate a long-acting intramuscular regimen for maintenance of virologic suppression (following induction with an oral regimen of GSK1265744 and abacavir/lamivudine) in human immunode ficiency virus type 1 (HIV-1) infected, antiretroviral therapy-naive adult subjects [Accessed 8 December 2014]
    • ClinicalTrials.gov. A phase IIb study to evaluate a long-acting intramuscular regimen for maintenance of virologic suppression (following induction with an oral regimen of GSK1265744 and abacavir/lamivudine) in human immunode ficiency virus type 1 (HIV-1) infected, antiretroviral therapy-naive adult subjects. http://clinicaltrials.gov/ct2/show/NCT02120352?term=gsk1265744&rank=16. [Accessed 8 December 2014].
  • 6
    • 84921044609 scopus 로고    scopus 로고
    • The long-acting integrase inhibitor GSK744 protects macaques from repeated intravaginal SHIV challenge
    • Radzio J, Spreen W, Yueh YL, et al. The long-acting integrase inhibitor GSK744 protects macaques from repeated intravaginal SHIV challenge. Sci Transl Med 2015; 7:270ra5.
    • (2015) Sci Transl Med , vol.7 , pp. 270ra5
    • Radzio, J.1    Spreen, W.2    Yueh, Y.L.3
  • 7
    • 84921047798 scopus 로고    scopus 로고
    • A long-acting integrase inhibitor protects female macaques from repeated high-dose intravaginal SHIV challenge
    • Andrews CD, Yueh YL, Spreen WR, et al. A long-acting integrase inhibitor protects female macaques from repeated high-dose intravaginal SHIV challenge. Sci Transl Med 2015; 7:270ra4.
    • (2015) Sci Transl Med , vol.7 , pp. 270ra4
    • Andrews, C.D.1    Yueh, Y.L.2    Spreen, W.R.3
  • 8
    • 84896769378 scopus 로고    scopus 로고
    • Long-acting integrase inhibitor protects macaques from intrarectal simian/human immunodeficiency virus
    • Andrews C, Spreen W, Mohri H, et al. Long-acting integrase inhibitor protects macaques from intrarectal simian/human immunodeficiency virus. Science 2014; 343:1151-1154.
    • (2014) Science , vol.343 , pp. 1151-1154
    • Andrews, C.1    Spreen, W.2    Mohri, H.3
  • 10
    • 79952025252 scopus 로고    scopus 로고
    • A prolonged release parenteral drug delivery system: An overview
    • Bari H. A prolonged release parenteral drug delivery system: an overview. Int J Pharm Sci Rev Res 2010; 3:1-11.
    • (2010) Int J Pharm Sci Rev Res , vol.3 , pp. 1-11
    • Bari, H.1
  • 11
    • 84925557632 scopus 로고    scopus 로고
    • GSK1265744 pharmacokinetics inplasma and tissue after single-dose long-acting injectable administration in healthy subjects
    • Spreen W, Ford SL, Chen S, et al. GSK1265744 pharmacokinetics inplasma and tissue after single-dose long-acting injectable administration in healthy subjects. J Acquir Immune Defic Syndr 2014; 67:481-486.
    • (2014) J Acquir Immune Defic Syndr , vol.67 , pp. 481-486
    • Spreen, W.1    Ford, S.L.2    Chen, S.3
  • 12
    • 84886089649 scopus 로고    scopus 로고
    • Long-acting injectable antiretrovirals for HIV treatment and prevention
    • Spreen WR, Margolis DA, Pottage JC Jr. Long-acting injectable antiretrovirals for HIV treatment and prevention. Curr Opin HIV AIDS 2013; 8:565-571.
    • (2013) Curr Opin HIV AIDS , vol.8 , pp. 565-571
    • Spreen, W.R.1    Margolis, D.A.2    Pottage, J.C.3
  • 13
    • 84886473877 scopus 로고    scopus 로고
    • Pharmacokinetics, safety, and monotherapy antiviral activity of GSK1265744, an HIV integrase strand transfer inhibitor
    • Spreen W, Min S, Ford SL, et al. Pharmacokinetics, safety, and monotherapy antiviral activity of GSK1265744, an HIV integrase strand transfer inhibitor. HIV Clin Trials 2013; 14:192-203.
    • (2013) HIV Clin Trials , vol.14 , pp. 192-203
    • Spreen, W.1    Min, S.2    Ford, S.L.3
  • 14
    • 0028299106 scopus 로고
    • Release and absorption rates of intramuscularly and subcutaneously injected pharmaceuticals (II)
    • Zuidema J, Kadir F, Titulaer HAC, Oussoren C. Release and absorption rates of intramuscularly and subcutaneously injected pharmaceuticals (II). Int J Pharm 1994; 105:189-207.
    • (1994) Int J Pharm , vol.105 , pp. 189-207
    • Zuidema, J.1    Kadir, F.2    Hac, T.3    Oussoren, C.4
  • 15
    • 84921020451 scopus 로고    scopus 로고
    • Pharmacokinetics, safety, and tolerability with repeat doses of GSK1265744 and rilpivirine (TMC278) long-acting nanosuspensions in healthy adults
    • Spreen W, Williams P, Margolis D, et al. Pharmacokinetics, safety, and tolerability with repeat doses of GSK1265744 and rilpivirine (TMC278) long-acting nanosuspensions in healthy adults. J Acquir Immune Defic Syndr 2014; 67:487-492.
    • (2014) J Acquir Immune Defic Syndr , vol.67 , pp. 487-492
    • Spreen, W.1    Williams, P.2    Margolis, D.3
  • 17
    • 84907878697 scopus 로고    scopus 로고
    • A compartmental pharmacokinetic evaluation of long-acting rilpivirine in HIV-negative volunteers for preexposure prophylaxis
    • Jackson AG, Else LJ, Mesquita PM, et al. A compartmental pharmacokinetic evaluation of long-acting rilpivirine in HIV-negative volunteers for preexposure prophylaxis. Clin Pharmacol Ther 2014; 96:314-323.
    • (2014) Clin Pharmacol Ther , vol.96 , pp. 314-323
    • Jackson, A.G.1    Else, L.J.2    Mesquita, P.M.3
  • 18
    • 84943174161 scopus 로고    scopus 로고
    • HIV PrEP dose rationale for cabotegravir (GSK1265744) long-acting injectable nanosuspension
    • 28-31 October Cape Town, South Africa; abstract A-671-0009-01071
    • Spreen W, Rinehart A, Smith K, et al. HIV PrEP dose rationale for cabotegravir (GSK1265744) long-acting injectable nanosuspension. Proceedings of the HIV Research for Prevention; 28-31 October 2014; Cape Town, South Africa; abstract A-671-0009-01071.
    • (2014) Proceedings of the HIV Research for Prevention;
    • Spreen, W.1    Rinehart, A.2    Smith, K.3
  • 20
    • 84943182099 scopus 로고    scopus 로고
    • In vitro drug interaction profile of the HIV integrase inhibitor, GSK1265744, and demonstrated lack of clinical interaction with midazolam
    • 19-21 May Washington, DC; abstract PP-20. 2014
    • Reese M, Ford S, Bowers G, et al. In vitro drug interaction profile of the HIV integrase inhibitor, GSK1265744, and demonstrated lack of clinical interaction with midazolam. Proceedings of the 15th International Workshop on Clinical Pharmacology of HIV and Hepatitis Therapy; 19-21 May 2014; Washington, DC; abstract PP-20. 2014.
    • (2014) Proceedings of the 15th International Workshop on Clinical Pharmacology of HIV and Hepatitis Therapy;
    • Reese, M.1    Ford, S.2    Bowers, G.3
  • 21
    • 84872050289 scopus 로고    scopus 로고
    • Effects of etravirine on the pharmacokinetics of the integrase inhibitor S/GSK1265744
    • Ford SL, Gould E, Chen S, et al. Effects of etravirine on the pharmacokinetics of the integrase inhibitor S/GSK1265744. Antimicrob Agents Chemother 2013; 57:277-280.
    • (2013) Antimicrob Agents Chemother , vol.57 , pp. 277-280
    • Ford, S.L.1    Gould, E.2    Chen, S.3
  • 22
    • 84885934539 scopus 로고    scopus 로고
    • Lack of pharmacokinetic interaction between rilpivirine and integrase inhibitors dolutegravir and GSK1265744
    • Ford SL, Gould E, Chen S, et al. Lack of pharmacokinetic interaction between rilpivirine and integrase inhibitors dolutegravir and GSK1265744. Antimicrob Agents Chemother 2013; 57:5472-5477.
    • (2013) Antimicrob Agents Chemother , vol.57 , pp. 5472-5477
    • Ford, S.L.1    Gould, E.2    Chen, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.