Changes in microRNAs associated with Twist-1 and Bcl-2 overexpression identify signaling pathways

Experimental and Molecular Pathology

Volumn 99, Issue 3, 2015, Pages 524-532

  Zhao, Nan ^a   Sun, Bao cun ^a   Zhao, Xiu lan ^a   Wang, Yong ^a   Sun, Hui zhi ^a   Dong, Xue yi ^a   Meng, Jie ^a   Gu, Qiang ^a  

^a TIANJIN MEDICAL UNIVERSITY   (China)

Author keywords

Bcl 2; EMT; MiRNAs; Twist 1; VM

Indexed keywords

MATRIGEL; MICRORNA; MICRORNA 27A; PROTEIN BCL 2; UNCLASSIFIED DRUG; BCL2 PROTEIN, HUMAN; NUCLEAR PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR TWIST; TWIST1 PROTEIN, HUMAN;

ANGIOGENESIS; ARTICLE; BCL 2 GENE; CELL STRUCTURE; CONTROLLED STUDY; EPITHELIAL MESENCHYMAL TRANSITION; GENE; GENE OVEREXPRESSION; METASTASIS; MICROARRAY ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS; SIGNAL TRANSDUCTION; TUMOR CELL; TUMOR INVASION; TWIST 1 GENE; WESTERN BLOTTING; WOUND HEALING; GENE EXPRESSION REGULATION; GENETICS; HUMAN; LIVER CELL CARCINOMA; LIVER TUMOR; METABOLISM; PATHOLOGY; TUMOR CELL LINE;

CARCINOMA, HEPATOCELLULAR; CELL LINE, TUMOR; EPITHELIAL-MESENCHYMAL TRANSITION; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; LIVER NEOPLASMS; MICRORNAS; NUCLEAR PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS; TWIST TRANSCRIPTION FACTOR;

EID: 84943145145     PISSN: 00144800     EISSN: 10960945     Source Type: Journal    
DOI: 10.1016/j.yexmp.2015.08.018     Document Type: Article

References (29)

1. Anon The Gene Ontology (GO) project in 2006. Nucleic Acids Res. 2006, 34:D322-D326.
2. Ashburner M., Ball C.A., Blake J.A., Botstein D., Butler H., Cherry J.M., Davis A.P., Dolinski K., Dwight S.S., Eppig J.T., Harris M.A., Hill D.P., Issel-Tarver L., Kasarskis A., Lewis S., Matese J.C., Richardson J.E., Ringwald M., Rubin G.M., Sherlock G. Gene ontology: tool for the unification of biology. The Gene Ontology Consortium. Nat. Genet. 2000, 25:25-29.
3. Baritaki S., Chapman A., Yeung K., Spandidos D.A., Palladino M., Bonavida B. Inhibition of epithelial to mesenchymal transition in metastatic prostate cancer cells by the novel proteasome inhibitor, NPI-0052: pivotal roles of Snail repression and RKIP induction. Oncogene 2009, 28:3573-3585.
4. Correia C., Lee S.H., Meng X.W., Vincelette N.D., Knorr K.L., Ding H., Nowakowski G.S., Dai H., Kaufmann S.H. Emerging understanding of Bcl-2 biology: implications for neoplastic progression and treatment. Biochim. Biophys. Acta 2015, 1853:1658-1671.
5. Dupuy D., Bertin N., Hidalgo C.A., Venkatesan K., Tu D., Lee D., Rosenberg J., Svrzikapa N., Blanc A., Carnec A., Carvunis A.R., Pulak R., Shingles J., Reece-Hoyes J., Hunt-Newbury R., Viveiros R., Mohler W.A., Tasan M., Roth F.P., Le Peuch C., Hope I.A., Johnsen R., Moerman D.G., Barabasi A.L., Baillie D., Vidal M. Genome-scale analysis of in vivo spatiotemporal promoter activity in Caenorhabditis elegans. Nat. Biotechnol. 2007, 25:663-668.
6. Gao G., Gay H.A., Chernock R.D., Zhang T.R., Luo J., Thorstad W.L., Lewis J.S., Wang X. A microRNA expression signature for the prognosis of oropharyngeal squamous cell carcinoma. Cancer 2012.
7. Grille S.J., Bellacosa A., Upson J., Klein-Szanto A.J., van Roy F., Lee-Kwon W., Donowitz M., Tsichlis P.N., Larue L. The protein kinase Akt induces epithelial mesenchymal transition and promotes enhanced motility and invasiveness of squamous cell carcinoma lines. Cancer Res. 2003, 63:2172-2178.
8. Han G., Lu S.L., Li A.G., He W., Corless C.L., Kulesz-Martin M., Wang X.J. Distinct mechanisms of TGF-beta1-mediated epithelial-to-mesenchymal transition and metastasis during skin carcinogenesis. J. Clin. Invest. 2005, 115:1714-1723.
9. Hess A.R., Seftor E.A., Gruman L.M., Kinch M.S., Seftor R.E.B., Hendrix M.J.C. VE-cadherin regulates EphA2 in aggressive melanoma cells through a novel signaling pathway - implications for vasculogenic mimicry. Cancer Biol. Ther. 2006, 5:228-233.
10. Hu X., Schwarz J.K., Lewis J.S., Huettner P.C., Rader J.S., Deasy J.O., Grigsby P.W., Wang X. A microRNA expression signature for cervical cancer prognosis. Cancer Res. 2010, 70:1441-1448.
11. Jiang L., Yang Y.D., Fu L., Xu W.Q., Liu D.B., Liang Q.Y., Zhang X., Xu L.X., Guan X.Y., Wu B., Sung J.J.Y., Yu J. CLDN3 inhibits cancer aggressiveness via Wnt-EMT signaling and is a potential prognostic biomarker for hepatocellular carcinoma. Oncotarget 2014, 5:7663-7676.
12. Kang Y., Massague J. Epithelial-mesenchymal transitions: twist in development and metastasis. Cell 2004, 118:277-279.
13. Li L., Li W. Epithelial-mesenchymal transition in human cancer: comprehensive reprogramming of metabolism, epigenetics, and differentiation. Pharmacol. Ther. 2015.
14. Lu J., Getz G., Miska E.A., Alvarez-Saavedra E., Lamb J., Peck D., Sweet-Cordero A., Ebert B.L., Mak R.H., Ferrando A.A., Downing J.R., Jacks T., Horvitz H.R., Golub T.R. MicroRNA expression profiles classify human cancers. Nature 2005, 435:834-838.
15. Maniotis A.J., Folberg R., Hess A., Seftor E.A., Gardner L.M., Pe'er J., Trent J.M., Meltzer P.S., Hendrix M.J. Vascular channel formation by human melanoma cells in vivo and in vitro: vasculogenic mimicry. Am. J. Pathol. 1999, 155:739-752.
16. Paulis Y.W., Soetekouw P.M., Verheul H.M., Tjan-Heijnen V.C., Griffioen A.W. Signalling pathways in vasculogenic mimicry. Biochim. Biophys. Acta 2010, 1806:18-28.
17. Reed J.C. Bcl-2-family proteins and hematologic malignancies: history and future prospects. Blood 2008, 111:3322-3330.
18. Rossato M., Curtale G., Tamassia N., Castellucci M., Mori L., Gasperini S., Mariotti B., De Luca M., Mirolo M., Cassatella M.A., Locati M., Bazzoni F. IL-10-induced microRNA-187 negatively regulates TNF-alpha, IL-6, and IL-12p40 production in TLR4-stimulated monocytes. Proc. Natl. Acad. Sci. U. S. A. 2012.
19. Schlitt T., Palin K., Rung J., Dietmann S., Lappe M., Ukkonen E., Brazma A. From gene networks to gene function. Genome Res. 2003, 13:2568-2576.
20. Shi X.B., Xue L., Yang J., Ma A.H., Zhao J., Xu M., Tepper C.G., Evans C.P., Kung H.J., deVere White R.W. An androgen-regulated miRNA suppresses Bak1 expression and induces androgen-independent growth of prostate cancer cells. Proc. Natl. Acad. Sci. U. S. A. 2007, 104:19983-19988.
21. Shi X.B., Xue L., Ma A.H., Tepper C.G., Gandour-Edwards R., Kung H.J., Devere White R.W. Tumor suppressive miR-124 targets androgen receptor and inhibits proliferation of prostate cancer cells. Oncogene 2012.
22. Sun T., Sun B.C., Zhao X.L., Zhao N., Dong X.Y., Che N., Yao Z., Ma Y.M., Gu Q., Zong W.K., Liu Z.Y. Promotion of tumor cell metastasis and vasculogenic mimicry by way of transcription coactivation by Bcl-2 and Twist1: a study of hepatocellular carcinoma. Hepatology 2011, 54:1690-1706.
23. Sun T., Zhao N., Zhao X.L., Gu Q., Zhang S.W., Che N., Wang X.H., Du J., Liu Y.X., Sun B.C. Expression and functional significance of Twist1 in hepatocellular carcinoma: its role in vasculogenic mimicry. Hepatology 2010, 51:545-556.
24. Sun W., Shen Z.Y., Zhang H., Fan Y.Z., Zhang W.Z., Zhang J.T., Lu X.S., Ye C. Overexpression of HIF-1 alpha in primary gallbladder carcinoma and its relation to vasculogenic mimicry and unfavourable prognosis. Oncol. Rep. 2012, 27:1990-2002.
25. Tse J.C., Kalluri R. Mechanisms of metastasis: epithelial-to-mesenchymal transition and contribution of tumor microenvironment. J. Cell. Biochem. 2007, 101:816-829.
26. Vartanian A., Gatsina G., Grigorieva I., Solomko E., Dombrovsky V., Baryshnikov A., Stepanova E. The involvement of Notch signaling in melanoma vasculogenic mimicry. Clin. Exp. Med. 2013, 13:201-209.
27. Volinia S., Calin G.A., Liu C.G., Ambs S., Cimmino A., Petrocca F., Visone R., Iorio M., Roldo C., Ferracin M., Prueitt R.L., Yanaihara N., Lanza G., Scarpa A., Vecchione A., Negrini M., Harris C.C., Croce C.M. A microRNA expression signature of human solid tumors defines cancer gene targets. Proc. Natl. Acad. Sci. U. S. A. 2006, 103:2257-2261.
28. Yip K.W., Reed J.C. Bcl-2 family proteins and cancer. Oncogene 2008, 27:6398-6406.
29. Zoni E., van der Pluijm G., Gray P.C., Kruithof-de Julio M. Epithelial plasticity in cancer: unmasking a MicroRNA network for TGF-beta-, Notch-, and Wnt-mediated EMT. J. Oncol. 2015, 2015:198967.