Development of the larval migration inhibition test for comparative analysis of ivermectin sensitivity in cyathostomin populations

Veterinary Parasitology

Volumn 212, Issue 3-4, 2015, Pages 292-298

  McArthur, Claire L ^a   Handel, Ian G ^b   Robinson, Ailie ^a   Hodgkinson, Jane E ^c   Bronsvoort, Barend Mde C ^b   Burden, Faith ^d   Kaplan, Ray M ^e   Matthews, Jacqueline B ^a  

^a MOREDUN RESEARCH INSTITUTE   (United Kingdom)

^b UNIVERSITY OF EDINBURGH   (United Kingdom)

^c UNIVERSITY OF LIVERPOOL   (United Kingdom)

^d THE DONKEY SANCTUARY   (United Kingdom)

^e UNIVERSITY OF GEORGIA   (United States)

Author keywords

Anthelmintic resistance; Cyathostomins; Ivermectin; Larval migration inhibition test

Indexed keywords

ANTHELMINTIC AGENT; IVERMECTIN; MOXIDECTIN; ANTIPARASITIC AGENT;

ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; CYATHOSTOMIN; DEVELOPMENTAL STAGE; DONKEY; DRUG SCREENING; DRUG SENSITIVITY; EC50; EQUIDAE; FECES ANALYSIS; HORSE; LARVAL DEVELOPMENT; MIGRATION INHIBITION; NEMATODE; NEMATODIASIS; NONHUMAN; UNITED KINGDOM; ANIMAL; DRUG EFFECTS; DRUG RESISTANCE; LARVA; MOTOR ACTIVITY;

ANIMALS; ANTIPARASITIC AGENTS; DRUG RESISTANCE; IVERMECTIN; LARVA; MOTOR ACTIVITY; NEMATODA;

EID: 84942991232     PISSN: 03044017     EISSN: 18732550     Source Type: Journal    
DOI: 10.1016/j.vetpar.2015.06.019     Document Type: Article

References (41)

1. Bello T.R. Alternative antiparasitic treatment of horses with pyrantel pamoate suspension and ivermectin oral solution compared with horses treated only with ivermectin oral solution. J. Eq. Vet. Sci. 1996, 16:18-21.
2. Canever R.J., Braga P.R., Boeckh A., Grycajuck M., Bier D., Molento M.B. Lack of cyathostomin sp. reduction after anthelmintic treatment in horses in Brazil. Vet. Parasitol. 2013, 194:35-39.
3. Christie M., Jackson F. Specific identification of strongyle eggs in small samples of sheep faeces. Res. Vet. Sci. 1982, 32:113-117.
4. Coles G.C., Bauer C., Borgsteede F.H., Geerts S., Klei T.R., Taylor M.A., Waller P.J. World Association for the Advancement of Veterinary Parasitology (W.A. A. V.P.) methods for the detection of anthelmintic resistance in nematodes of veterinary importance. Vet. Parasitol. 1992, 44:35-44.
5. Cwiklinski K., Kooyman F.N., Van Doorn D.C., Matthews J.B. New insights into sequence variation in the IGS region of 21 cyathostomin species and the implication for molecular identification. Parasitology 2012, 139:1063-1073.
6. Demeler J., Küttler U., El-Abdellati A., Stafford K., Rydzik A., Varaday M., Kenyon F., Jackson F., Vercruysse J., von Samson-Himmelstjerna G. Standardization of the larval migration inhibition test for the detection of resistance of ivermectin in gastrointestinal nematodes of ruminants. Vet. Parasitol. 2010, 174:58-64.
7. Demeler J., Kleinschmidt N., Küttler U., Koopmann R., von Samson-Himmelstjerna G. Evaluation of the egg hatch assay and the larval migration inhibition assay to detect anthelmintic resistance in cattle parasitic nematodes on farms. Parasitol. Int. 2012, 61:614-618.
8. Demeler J., Gill J.H., von Samson-Himmelstjerna G., Sangster, NC The in vitro assay profile of macrocyclic lactone resistance in three species of sheep trichostrongyloids. Int. J. Parasitol. Drugs Drug Resist. 2013, 3:109-118.
9. Denwood M.J., Reid S.W., Love S., Nielsen M.K., Matthews L., McKendrick I.J., Innocent G.T. Comparison of three alternative methods for analysis of equine Faecal Egg Count Reduction Test data. Prev. Vet. Med. 2010, 93:316-323.
10. DiPietro J.A., D, Lockc T.F., Walkerd K., Paul A.J., Shipleyc C., Rullie D. Clinical trial of moxidectin oral gel in horses. Vet. Parasitol. 1997, 72:167-177.
11. Folz S.D., Pax R.A., Thomas E.M., Bennet J.L., Lee B.L., Conder G.A. Development and validation of an in vitro Trichostrongylus colubriformis motility assay. Int. J. Parasitol. 1987, 17:1441-1444.
12. Gill, J.H., Lacey, E., 1998. Avermectin/milbemycin resistance in trichostrongyloid nematodes.
13. Jackson F., Coop R.L. The development of anthelmintic resistance in sheep nematodes. Parasitology 2000, 120(Suppl):S95-S107.
14. Kaplan R.M. Anthelmintic resistance in nematodes of horses. Vet. Res. 2002, 33:491-507.
15. Kaplan R.M., Klei T.R., Lyons E.T., Lester G., Courtney C.H., French D.D., Tolliver S.C., Vidyashankar A.N., Zhao Y. Prevalence of anthelmintic resistant cyathostomes on horse farms. J. Am. Vet. Med. Assoc. 2004, 225:903-910.
16. Lester H.E., Spanton J., Stratford C.A., Bartley D.J., Morgan E.R., Hodgkinson J.E., Coumbe K., Mair T., Swane B., Lemone G., Cookson R., Matthews J.B. Anthelmintic efficacy against cyathostomins in horses in England. Vet. Parasitol. 2013, 197:189-196.
17. Lichtenfels J.R., Kharchenko V.A., Dvojnos G.M. Illustrated identification keys to strongylid parasites (strongylidae: Nematoda) of horses, zebras and asses (Equidae). Vet. Parasitol. 2008, 156:4-161.
18. Lind E.O., Uggla A., Waller P., Höglund J. Larval development assay for detection of anthelmintic resistance in cyathostomins of Swedish horses. Vet. Parasitol. 2005, 128:261-269.
19. Lyons E.T., Drudge J.H., Tolliver S.C., Granstrom D.E., Stamper S. Evaluation of exclusive use of ivermectin vs. alternation of antiparasitic compounds for control of internal parasites of horses. Am. J. Vet. Res. 1992, 52:97-104.
20. Martin P.J., Le Jambre L.F. Larval paralysis as an in vitro assay of levamisole and morantel tartrate resistance in Ostertagia. Vet. Sci. Comm. 1979, 3:159-164.
21. Matthee S., Krecek R.C., McGeoch, MA A comparison of the intestinal helminth communities of Equidae in Southern Africa. J. Parasitol. 2004, 90:1263-1273.
22. Matthews J.B. Anthelmintic resistance in equine nematodes. Int. J. Parasit Drugs Drug Resistance 2014, 4:310-315.
23. Matthews J.B., McArthur C., Robinson A., Jackson F. The in vitro diagnosis of anthelmintic resistance in cyathostomins. Vet. Parasitol. 2012, 185:25-31.
24. McKellar Q.A. Ecotoxicology and residues of anthelmintic compounds. Vet. Parasitol. 1997, 72:413. 426.
25. Molan A.L., Waghorns G.C., Min B.R., McNabb W.C. The effect of condensed tannins from seven herbages on Trichostrongylus colubriformis larval migration in vitro. Folia Parasitol. 2000, 47:39-44.
26. Molento M.B., Antunes J., Bentes R.N., Coles G.C. Anthelmintic resistant nematodes in Brazilian horses. Vet. Rec. 2008, 162:384-385.
27. Molento M.B., Nielsen M.K., Kaplan R.M. Resistance to avermectin/milbemycin anthelmintics in equine cyathostomins - current situation. Vet. Parasitol. 2012, 185:16-24.
28. Love S., Murphy D., Mellor D. Pathogenicity of cyathostome infection. Vet. Parasitol. 1999, 85:113-121.
29. R. Development Core Team. 2012. R: A language and environment for statistical computing. R Foundation for Statistical Computing, Vienna, Austria. ISBN 3-900051-07-0, URL http://www.R-project.org.
30. Relf V.E., Lester H.E., Morgan E.R., Hodgkinson J.E., Matthews J.B. Anthelmintic efficacy on UK Thoroughbred stud farms. Int. J. Parasitol. 2014, 44:507-514.
31. Sangster N.C., Riley F.L., Collins G.H. Investigation of the mechanism of levamisole resistance in trichostrongylid nematodes of sheep. Int. J. Parasitol. 1988, 18:813-818.
32. Shoop W.L., Mrozik H., Fisher M.H. Structure and activity of avermectins and milbemycins in animal health. Vet. Parasitol. 1995, 59:139-156.
33. Siegel S., Castellan N.J. Nonparametric statistics for the behavioural sciences. Nonparametric statistics for the behavioural sciences 1989, 213-214. 2nd ed.
34. ®) for the detection of anthelmintic resistance in cyathostomin nematodes of horses. Vet. Parasitol. 2004, 121:125-142.
35. Thienpont D., Rochette F., Vanparijs O.F. Diagnosing helminthiasis by coprological examination 1986, 85. Janssen Research Foundation, Beerse, Belguim. 2nd ed.
36. Traversa D., Castagna G., von Samson-Himmelstjerna G., Meloni S., Bartolini R., Geurden T., Pearce M.C., Woringer E., Besognet B., Milillo P., D'Espois, M Efficacy of major anthelmintics against horse cyathostomins in France. Vet. Parasitol. 2012, 188:294-300.
37. Trawford A.F., Burden F., Hodgkinson J., 2005. Suspected moxidectin resistance in two donkey herds at The Donkey Sanctuary. Proceedings of the 20th International Conference of the WAAVP, Christchurch, New Zealand.
38. Trawford, A.F., Burden, F., 2009. Ivermectin resistance in cyathostomes in four donkeys herds at the Donkey Sanctuary, UK. Proceedings of the 22nd International Conference of the WAAVP, Calgary, Canada.
39. van Doorn D.C., Kooyman F.N., Eysker M., Hodgkinson J.E., Wagenaar J.A., Ploeger H.W. In vitro selection and differentiation of ivermectin resistant cyathostomin larvae. Vet. Parasitol. 2010, 174:292-299.
40. Vidyashankar A.N., Hanlon B.M., Kaplan R.M. Statistical and biological considerations in evaluating drug efficacy in equine strongyle parasites using fecal egg count data. Vet. Parasitol. 2012, 185:45-56.
41. Wood E.L., Matthews J.B., Stephenson S., Slote M., Nussey D.H. Variation in fecal egg counts in horses managed for conservation purposes: individual egg shedding consistency, age effects and seasonal variation. Parasitology 2012, 140:115-128.