SH2B3 Is a Genetic Determinant of Cardiac Inflammation and Fibrosis

Circulation: Cardiovascular Genetics

Volumn 8, Issue 2, 2015, Pages 294-304

  Flister, Michael J ^a,b   Hoffman, Matthew J ^a,b   Lemke, Angela ^a,b   Prisco, Sasha Z ^a,b   Rudemiller, Nathan ^b   O'Meara, Caitlin C ^e   Tsaih, Shirng Wern ^a   Moreno, Carol ^f   Geurts, Aron M ^a   Lazar, Jozef ^a,c   Adhikari, Neeta ^g   Hall, Jennifer L ^g   Jacob, Howard J ^a,d  

^a Human and Molecular Genetics Center   (United States)

^b Departments of Physiology   (United States)

^c Departments of Dermatology   (United States)

^d MEDICAL COLLEGE OF WISCONSIN   (United States)

^e BRIGHAM AND WOMEN S HOSPITAL   (United States)

^f MEDIMMUNE   (United States)

^g UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

Author keywords

genetics; myocardial fibrosis; myocardial infarction; rats

Indexed keywords

MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1; PROTEIN; SH2B ADAPTOR PROTEIN 3; UNCLASSIFIED DRUG; LNK PROTEIN, RAT; MUSCLE PROTEIN;

ALLELE; ANGIOGENESIS; ANGIOGENESIS ASSAY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CAPILLARY DENSITY; CARDITIS; CELL INFILTRATION; CHROMOSOME 12; COMPARATIVE STUDY; CONTROLLED STUDY; DIASTOLE; EXON; EXPERIMENTAL CORONARY OCCLUSION; FEMALE; FRAMESHIFT MUTATION; GENE EXPRESSION; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENOTYPE; HAPLOTYPE; HEART FAILURE; HEART INFARCTION; HEART LEFT VENTRICLE CONTRACTILITY; HEART MUSCLE FIBROSIS; HEART MUSCLE INJURY; HUMAN; HUMAN CHROMOSOME; HUMAN TISSUE; IMMUNOFLUORESCENCE TEST; IMMUNOHISTOCHEMISTRY; LEFT ANTERIOR DESCENDING CORONARY ARTERY; LEUKOCYTE; MACROPHAGE; MONOCYTE; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE TRAIT LOCUS; RAT; REAL TIME ULTRASOUND SCANNER; REPERFUSION INJURY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSTHORACIC ECHOCARDIOGRAPHY; WESTERN BLOTTING; ANIMAL; COMPLICATION; DISEASE MODEL; FIBROSIS; GENETICS; METABOLISM; MUTANT RAT STRAIN; MYOCARDITIS; PATHOLOGY;

ANIMALS; DISEASE MODELS, ANIMAL; FIBROSIS; MUSCLE PROTEINS; MYOCARDIAL INFARCTION; MYOCARDITIS; PROTEINS; RATS; RATS, MUTANT STRAINS;

EID: 84942919523     PISSN: 1942325X     EISSN: 19423268     Source Type: Journal    
DOI: 10.1161/CIRCGENETICS.114.000527     Document Type: Article

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