Farnesoid X receptor agonist CDCA reduces blood pressure and regulates vascular tone in spontaneously hypertensive rats

Journal of the American Society of Hypertension

Volumn 9, Issue 7, 2015, Pages 507-516.e7

  Li, Chenyu ^a   Li, Jing ^b   Weng, Xu ^a   Lan, Xiaofang ^a   Chi, Xiangbo ^c  

^a Chongqing Hospital of Traditional Chinese Medicine   (China)

^b THE FIRST AFFILIATED HOSPITAL OF CHONGQING MEDICAL UNIVERSITY   (China)

^c Qijiang People's Hospital   (China)

Author keywords

Bile Acid; Hypertension; Inflammation; Nitric oxide; Nuclear receptor

Indexed keywords

3 [2 [2 CHLORO 4 [3 (2,6 DICHLOROPHENYL) 5 ISOPROPYL 4 ISOXAZOLYLMETHOXY]PHENYL]VINYL]BENZOIC ACID; ACETYLCHOLINE; CALCIUM ACTIVATED POTASSIUM CHANNEL; CHENODEOXYCHOLIC ACID; ENDOTHELIAL NITRIC OXIDE SYNTHASE; ENDOTHELIN 1; MESSENGER RNA; TRANSCRIPTION FACTOR RELA; VASCULAR CELL ADHESION MOLECULE 1; ANTIHYPERTENSIVE AGENT; CELL RECEPTOR; FARNESOID X-ACTIVATED RECEPTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; NITRIC OXIDE SYNTHASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; BLOOD VESSEL TONE; CONCENTRATION RESPONSE; CONFERENCE PAPER; CONTROLLED STUDY; ELEVATED BLOOD PRESSURE; ESSENTIAL HYPERTENSION; MALE; MESENTERIC ARTERY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SPONTANEOUSLY HYPERTENSIVE RAT; SYSTOLIC BLOOD PRESSURE; TREATMENT DURATION; UPREGULATION; VASOCONSTRICTION; VASODILATATION; WISTAR KYOTO RAT; AGONISTS; ANIMAL; BIOSYNTHESIS; DISEASE MODEL; DRUG EFFECTS; GENETICS; HYPERTENSION; METABOLISM;

ANIMALS; ANTIHYPERTENSIVE AGENTS; CHENODEOXYCHOLIC ACID; DISEASE MODELS, ANIMAL; ENDOTHELIN-1; HYPERTENSION; MESENTERIC ARTERIES; NF-KAPPA B; NITRIC OXIDE SYNTHASE; RATS, INBRED SHR; RATS, INBRED WKY; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RNA, MESSENGER; VASCULAR CELL ADHESION MOLECULE-1; VASOCONSTRICTION; VASODILATION;

EID: 84942883438     PISSN: 19331711     EISSN: 18787436     Source Type: Journal    
DOI: 10.1016/j.jash.2015.04.006     Document Type: Conference Paper

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