Cardiometabolic risks and severity of obesity in children and young adults

New England Journal of Medicine

Volumn 373, Issue 14, 2015, Pages 1307-1317

  Skinner, Asheley C ^a,b   Perrin, Eliana M ^a   Moss, Leslie A ^c   Skelton, Joseph A ^d  

^a School of Medicine   (United States)

^b UNC Gillings School of Global Public Health   (United States)

^c Injury Prevention Research Center   (United States)

^d UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; GLYCOSYLATED HEMOGLOBIN; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN CHOLESTEROL; TRIACYLGLYCEROL; BIOLOGICAL MARKER;

ADOLESCENT; ADULT; ARTICLE; CARDIOMETABOLIC RISK; CHILD; CHILDHOOD OBESITY; CROSS-SECTIONAL STUDY; DIASTOLIC BLOOD PRESSURE; DISEASE ASSOCIATION; DISEASE SEVERITY; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; PRESCHOOL CHILD; PREVALENCE; PRIORITY JOURNAL; SCHOOL CHILD; SEX DIFFERENCE; SYSTOLIC BLOOD PRESSURE; YOUNG ADULT; BLOOD; BODY MASS; CLASSIFICATION; HYPERTENSION; NUTRITION; OBESITY; OVERWEIGHT; RISK FACTOR; SEVERITY OF ILLNESS INDEX; SEX RATIO; STATISTICAL MODEL;

ADOLESCENT; BIOLOGICAL MARKERS; BODY MASS INDEX; CHILD; CHILD, PRESCHOOL; CHOLESTEROL, HDL; CROSS-SECTIONAL STUDIES; FEMALE; HEMOGLOBIN A, GLYCOSYLATED; HUMANS; HYPERTENSION; LINEAR MODELS; MALE; NUTRITION SURVEYS; OBESITY; OVERWEIGHT; PREVALENCE; RISK FACTORS; SEVERITY OF ILLNESS INDEX; SEX DISTRIBUTION; TRIGLYCERIDES; YOUNG ADULT;

EID: 84942857234     PISSN: 00284793     EISSN: 15334406     Source Type: Journal    
DOI: 10.1056/NEJMoa1502821     Document Type: Article

References (39)

1. Skinner AC, Skelton JA. Prevalence and trends in obesity and severe obesity among children in the United States, 1999-2012. JAMA Pediatr 2014; 168: 561-6.
2. Skelton JA, Cook SR, Auinger P, Klein JD, Barlow SE. Prevalence and trends of severe obesity among US children and adolescents. Acad Pediatr 2009; 9: 322-9.
3. Skinner AC, Mayer ML, Flower K, Weinberger M. Health status and health care expenditures in a nationally representative sample: how do overweight and healthy-weight children compare? Pediatrics 2008; 121(2): e269-e277.
4. Kelly AS, Barlow SE, Rao G, et al. Severe obesity in children and adolescents: identification, associated health risks, and treatment approaches: A scientific statement from the American Heart Association. Circulation 2013; 128: 1689-712.
5. National Center for Health Statistics. National Health and Nutrition Examination Survey 1999-2014 survey content brochure (http://www.cdc.gov/nchs/data/nhanes/survey-content-99-14.pdf).
6. Centers for Disease Control and Prevention. A SAS program for the 2000 CDC growth charts: (ages 0 to <20 years). 2011 (http://www.cdc.gov/nccdphp/dnpao/growthcharts/resources/sas.htm).
7. Barlow SE. Expert committee recommendations regarding the prevention, assessment, and treatment of child and adolescent overweight and obesity: summary report. Pediatrics 2007; 120: Suppl 4: S164- S192.
8. Flegal KM, Wei R, Ogden CL, Freedman DS, Johnson CL, Curtin LR. Characterizing extreme values of body mass index-for-age by using the 2000 Centers for Disease Control and Prevention growth charts. Am J Clin Nutr 2009; 90: 1314-20.
9. Berrington de Gonzalez A, Hartge P, Cerhan JR, et al. Body-mass index and mortality among 1.46 million white adults. N Engl J Med 2010; 363: 2211-9.
10. Expert Panel on Integrated Guidelines for Cardiovascular Health and Risk Reduction in Children and Adolescents, National Heart, Lung, and Blood Institute. Expert panel on integrated guidelines for cardiovascular health and risk reduction in children and adolescents: summary report. Pediatrics 2011; 128: Suppl 5: S213-S256.
11. Daniels SR, Greer FR. Lipid screening and cardiovascular health in childhood. Pediatrics 2008; 122: 198-208.
12. Kavey RE, Daniels SR, Lauer RM, Atkins DL, Hayman LL, Taubert K. American Heart Association guidelines for primary prevention of atherosclerotic cardiovascular disease beginning in childhood. Circulation 2003; 107: 1562-6.
13. National High Blood Pressure Education Program Working Group on High Blood Pressure in Children and Adolescents. The fourth report on the diagnosis, evaluation, and treatment of high blood pressure in children and adolescents. Pediatrics 2004; 114: Suppl 2: 555-76.
14. Chobanian AV, Bakris GL, Black HR, et al. The seventh report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure: The JNC 7 report. JAMA 2003; 289: 2560-72.
15. American Diabetes Association. Diagnosis and classification of diabetes mellitus. Diabetes Care 2014; 37: Suppl 1: S81-S90.
16. Centers for Disease Control and Prevention. National Health and Nutrition Examination Survey (NHANES) laboratory procedures manual 2011 (http://www.cdc.gov/nchs/data/nhanes/nhanes-11-12/2011-12-Laboratory-Procedures-Manual.pdf).
17. Steiner MJ, Skinner AC, Perrin EM. Fasting might not be necessary before lipid screening: A nationally representative cross-sectional study. Pediatrics 2011; 128: 463-70.
18. Johnson CL, Paulose-Ram R, Ogden CL, et al. National Health and Nutrition Examination Survey: Analytic guidelines, 1999-2010. Vital Health Stat 2 2013; 161: 1-24.
19. Centers for Disease Control and Prevention. National Health and Nutrition Examination Survey: Analytic guidelines, 2011-2012. 2013 (http://www.cdc.gov/nchs/data/nhanes/analytic-guidelines-11-12.pdf).
20. Kit BK, Kuklina E, Carroll MD, Ostchega Y, Freedman DS, Ogden CL. Prevalence of and trends in dyslipidemia and blood pressure among US children and adolescents, 1999-2012. JAMA Pediatr 2015; 169: 272-9.
21. Krebs NF, Himes JH, Jacobson D, Nicklas TA, Guilday P, Styne D. Assessment of child and adolescent overweight and obesity. Pediatrics 2007; 120: Suppl 4: S193-S228.
22. Freedman DS, Mei Z, Srinivasan SR, Berenson GS, Dietz WH. Cardiovascular risk factors and excess adiposity among overweight children and adolescents: The Bogalusa Heart Study. J Pediatr 2007; 150(1): 12.e2-17.e2.
23. Freedman DS, Dietz WH, Srinivasan SR, Berenson GS. The relation of overweight to cardiovascular risk factors among children and adolescents: The Bogalusa Heart Study. Pediatrics 1999; 103: 1175-82.
24. Lambert M, Delvin EE, Levy E, et al. Prevalence of cardiometabolic risk factors by weight status in a populationbased sample of Quebec children and adolescents. Can J Cardiol 2008; 24: 575- 83.
25. Field AE, Cook NR, Gillman MW. Weight status in childhood as a predictor of becoming overweight or hypertensive in early adulthood. Obes Res 2005; 13: 163-9.
26. Guo SS, Wu W, Chumlea WC, Roche AF. Predicting overweight and obesity in adulthood from body mass index values in childhood and adolescence. Am J Clin Nutr 2002; 76: 653-8.
27. Engeland A, Bjørge T, Tverdal A, Søgaard AJ. Obesity in adolescence and adulthood and the risk of adult mortality. Epidemiology 2004; 15: 79-85.
28. Franks PW, Hanson RL, Knowler WC, Sievers ML, Bennett PH, Looker HC. Childhood obesity, other cardiovascular risk factors, and premature death. N Engl J Med 2010; 362: 485-93.
29. Inge TH, King WC, Jenkins TM, et al. The effect of obesity in adolescence on adult health status. Pediatrics 2013; 132: 1098-104.
30. Whitlock EP, O'Connor EA, Williams SB, Beil TL, Lutz KW. Effectiveness of weight management interventions in children: A targeted systematic review for the USPSTF. Pediatrics 2010; 125(2): e396-e418.
31. Children's Hospital Association. Obesity services: 2013 survey findings of children's hospitals (https://www.childrenshospitals.org//media/Files/CHA/Main/Issues-and-Advocacy/Key-Issues/Child-Health/Obesity/2013-survey-findings-obesity-services-report-050114.pdf ).
32. Finkelstein EA, Trogdon JG, Brown DS, Allaire BT, Dellea PS, Kamal-Bahl SJ. The lifetime medical cost burden of overweight and obesity: implications for obesity prevention. Obesity (Silver Spring) 2008; 16: 1843-8.
33. Wang YC, McPherson K, Marsh T, Gortmaker SL, Brown M. Health and economic burden of the projected obesity trends in the USA and the UK. Lancet 2011; 378: 815-25.
34. Trasande L, Chatterjee S. The impact of obesity on health service utilization and costs in childhood. Obesity (Silver Spring) 2009; 17: 1749-54.
35. Johnston CA, Tyler C, Palcic JL, Stansberry SA, Gallagher MR, Foreyt JP. Smaller weight changes in standardized body mass index in response to treatment as weight classification increases. J Pediatr 2011; 158: 624-7.
36. Kalarchian MA, Levine MD, Arslanian SA, et al. Family-based treatment of severe pediatric obesity: randomized, controlled trial. Pediatrics 2009; 124: 1060-8.
37. Danielsson P, Kowalski J, Ekblom Ö., Marcus C. Response of severely obese children and adolescents to behavioral treatment. Arch Pediatr Adolesc Med 2012; 166: 1103-8.
38. Schwimmer JB, Burwinkle TM, Varni JW. Health-related quality of life of severely obese children and adolescents. JAMA 2003; 289: 1813-9.
39. Dietz WH, Baur LA, Hall K, et al. Management of obesity: improvement of health-care training and systems for prevention and care. Lancet 2015; 385: 2521-33.