Fertility in women with rheumatoid arthritis: Influence of disease activity and medication

Annals of the Rheumatic Diseases

Volumn 74, Issue 10, 2015, Pages 1836-1841

  Brouwer, Jenny ^a   Hazes, Johanna M W ^a   Laven, Joop S E ^a   Dolhain, Radboud J E M ^a  

^a ERASMUS MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ADALIMUMAB; AZATHIOPRINE; CYCLIC CITRULLINATED PEPTIDE ANTIBODY; CYCLOOXYGENASE 2 INHIBITOR; ETANERCEPT; GOLD DERIVATIVE; HYDROXYCHLOROQUINE; INFLIXIMAB; LEFLUNOMIDE; METHOTREXATE; NONSTEROID ANTIINFLAMMATORY AGENT; PREDNISONE; RECOMBINANT INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; RHEUMATOID FACTOR; SALAZOSULFAPYRIDINE; GLUCOCORTICOID;

ADULT; AGE; ARTICLE; COHORT ANALYSIS; CONTROLLED STUDY; DISEASE ACTIVITY; DISEASE ASSOCIATION; DISEASE DURATION; DRUG USE; FEMALE; FEMALE FERTILITY; FIRST TRIMESTER PREGNANCY; HUMAN; MAJOR CLINICAL STUDY; MATERNAL CARE; NULLIPARA; PRIORITY JOURNAL; PROPORTIONAL HAZARDS MODEL; PROSPECTIVE STUDY; RHEUMATOID ARTHRITIS; SMOKING; TIME TO PREGNANCY; ARTHRITIS, RHEUMATOID; COMPLICATION; DOSE RESPONSE; DRUG EFFECTS; INFERTILITY, FEMALE; PARITY; PREGNANCY; RISK FACTOR; SEVERITY OF ILLNESS INDEX; SURVIVAL;

ADULT; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ARTHRITIS, RHEUMATOID; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; GLUCOCORTICOIDS; HUMANS; INFERTILITY, FEMALE; PARITY; PREDNISONE; PREGNANCY; PROSPECTIVE STUDIES; RISK FACTORS; SEVERITY OF ILLNESS INDEX; SURVIVAL ANALYSIS; TIME-TO-PREGNANCY;

EID: 84942852804     PISSN: 00034967     EISSN: 14682060     Source Type: Journal    
DOI: 10.1136/annrheumdis-2014-205383     Document Type: Article

References (40)

1. Skomsvoll JF, Ostensen M, Baste V, et al. Number of births, interpregnancy interval, and subsequent pregnancy rate after a diagnosis of inflammatory rheumatic disease in Norwegian women. J Rheumatol 2001;28:2310-14.
2. Clowse ME, Chakravarty E, Costenbader KH, et al. Effects of infertility, pregnancy loss, and patient concerns on family size of women with rheumatoid arthritis and systemic lupus erythematosus. Arthritis Care Res (Hoboken) 2012;64:668-74.
3. Jawaheer D, Zhu JL, Nohr EA, et al. Time to pregnancy among women with rheumatoid arthritis. Arthritis Rheum 2011;63:1517-21.
4. de Man YA, Hazes JM, van der Heide H, et al. Association of higher rheumatoid arthritis disease activity during pregnancy with lower birth weight: results of a national prospective study. Arthritis Rheum 2009;60:3196-206.
5. Hargreaves ER. A survey of rheumatoid arthritis in West Cornwall. A report to the Empire Rheumatism Council. Ann Rheum Dis 1958;17:61-75.
6. Kay A, Bach F. Subfertility before and after the development of rheumatoid arthritis in women. Ann Rheum Dis 1965;24:169-73.
7. Del Junco DJ, Annegers JF, Coulam CB, et al. The relationship between rheumatoid arthritis and reproductive function. Br J Rheumatol 1989;28(Suppl 1):33; discussion 42-5.
8. Wallenius M, Skomsvoll JF, Irgens LM, et al. Fertility in women with chronic inflammatory arthritides. Rheumatology (Oxford) 2011;0:1162-7.
9. Wallenius M, Skomsvoll J, Irgens L, et al. Parity in patients with chronic inflammatory arthritides childless at time of diagnosis. Scand J Rheumatol 2012;41:202-7.
10. de Man YA, Dolhain RJ, van de Geijn FE, et al. Disease activity of rheumatoid arthritis during pregnancy: results from a nationwide prospective study. Arthritis Rheum 2008;59:1241-8.
11. Arnett FC, Edworthy SM, Bloch DA, et al. The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum 1988;31:315-24.
12. de Man YA, Hazes JM, van de Geijn FE, et al. Measuring disease activity and functionality during pregnancy in patients with rheumatoid arthritis. Arthritis Rheum 2007;57:716-22.
13. van Riel P, van Gestel AM, Scott DG. Interpreting disease course. In: van Riel PL, vGA Scott DG, eds. EULAR handbook of clinical assessments in rheumatoid arthritis. Alphen aan den Rijn: Van Zuiden Communications, 2000:39-43.
14. de Man YA, Bakker-Jonges LE, Goorbergh CM, et al. Women with rheumatoid arthritis negative for anti-cyclic citrullinated peptide and rheumatoid factor are more likely to improve during pregnancy, whereas in autoantibody-positive women autoantibody levels are not influenced by pregnancy. Ann Rheum Dis 2010;69:420-3.
15. Boivin J, Bunting L, Collins JA, et al. International estimates of infertility prevalence and treatment-seeking: potential need and demand for infertility medical care. Hum Reprod 2007;22:1506-12.
16. Juul S, Karmaus W, Olsen J. Regional differences in waiting time to pregnancy: pregnancy-based surveys from Denmark, France, Germany, Italy and Sweden. The European Infertility and Subfecundity Study Group. Hum Reprod 1999;14:1250-4.
17. te Velde ER, Pearson PL. The variability of female reproductive ageing. Hum Reprod Update 2002;8:141-54.
18. Central Bureau of Statistics. The Hague/Heerlen. The Netherlands: www.cbs.nl, 2013.
19. Hunault CC, Habbema JD, Eijkemans MJ, et al. Two new prediction rules for spontaneous pregnancy leading to live birth among subfertile couples, based on the synthesis of three previous models. Hum Reprod 2004;19:2019-26.
20. Katz PP. Childbearing decisions and family size among women with rheumatoid arthritis. Arthritis Rheum 2006;55:217-23.
21. Biedermann L, Rogler G, Vavricka SR, et al. Pregnancy and breastfeeding in inflammatory bowel disease. Digestion 2012;86(Suppl 1):45-54.
22. Van Sinderen M, Menkhorst E, Winship A, et al. Preimplantation human blastocyst-endometrial interactions: the role of inflammatory mediators. Am J Reprod Immunol 2012;69:427-40.
23. de Steenwinkel FD, Hokken-Koelega AC, de Man YA, et al. Circulating maternal cytokines influence fetal growth in pregnant women with rheumatoid arthritis. Ann Rheum Dis 2012;72:1995-2001.
24. Micu MC, Micu R, Ostensen M. Luteinized unruptured follicle syndrome increased by inactive disease and selective cyclooxygenase 2 inhibitors in women with inflammatory arthropathies. Arthritis Care Res (Hoboken) 2011;63:1334-8.
25. Mendonca LL, Khamashta MA, Nelson-Piercy C, et al. Non-steroidal anti-inflammatory drugs as a possible cause for reversible infertility. Rheumatology (Oxford) 2000;39:880-2.
26. Janssen NM, Genta MS. The effects of immunosuppressive and anti-inflammatory medications on fertility, pregnancy, and lactation. Arch Intern Med 2000;160:610-19.
27. Hazes JMW, de Man YA. Antirheumatic drugs in pregnancy and lactation. In: Isenberg DA, Maddison PJ, Woo P, Glass D, Breedveld FC, eds. Oxford Textbook of Rheumatology. 3rd edn. Oxford, UK, 2004:126-34.
28. Saketos M, Sharma N, Santoro NF. Suppression of the hypothalamic-pituitaryovarian axis in normal women by glucocorticoids. Biol Reprod 1993;49:1270-6.
29. Sakakura M, Takebe K, Nakagawa S. Inhibition of luteinizing hormone secretion induced by synthetic LRH by long-term treatment with glucocorticoids in human subjects. J Clin Endocrinol Metab 1975;40:774-9.
30. Whirledge S, Cidlowski JA. Glucocorticoids, stress, and fertility. Minerva Endocrinol 2010;35:109-25.
31. Cooke PS, Holsberger DR, Witorsch RJ, et al. Thyroid hormone, glucocorticoids, and prolactin at the nexus of physiology, reproduction, and toxicology. Toxicol Appl Pharmacol 2004;194:309-35.
32. Hagino N. The effect of synthetic corticosteroids on ovarian function in the baboon. J Clin Endocrinol Metab 1972;35:716-21.
33. Karri S. G. V. Effect of methotrexate and leucovorin on female reproductive tract of albino rats. Cell Biochem Funct 2011;29:1-21.
34. Brouwer J, Laven JS, Hazes JM, et al. Levels of serum anti-Mullerian hormone, a marker for ovarian reserve, in women with rheumatoid arthritis. Arthritis Care Res (Hoboken) 2013;65:1534-38.
35. Jungheim ES, Moley KH. Current knowledge of obesity's effects in the pre- and periconceptional periods and avenues for future research. Am J Obstet Gynecol 2010;203:525-30.
36. van der Steeg JW, Steures P, Eijkemans MJ, et al. Obesity affects spontaneous pregnancy chances in subfertile, ovulatory women. Hum Reprod 2008;23:324-8.
37. Stavropoulos-Kalinoglou A, Metsios GS, Koutedakis Y, et al. Obesity in rheumatoid arthritis. Rheumatology (Oxford) 2011;50:450-62.
38. Jurgens MS, Jacobs JW, Geenen R, et al. Increase of body mass index in a tight controlled methotrexate-based strategy with prednisone in early rheumatoid arthritis: side effect of the prednisone or better control of disease activity? Arthritis Care Res (Hoboken) 2013;65:88-93.
39. de Steenwinkel FD, Hokken-Koelega AC, de Ridder MA, et al. Rheumatoid arthritis during pregnancy and postnatal catch-up growth in the offspring. Arthritis Rheumatol 2014. doi:10.1002/art.38519. [Epub ahead of print].
40. de Steenwinkel FD, Hokken-Koelega AC, Hazes JM, et al. The influence of foetal prednisone exposure on the cortisol levels in the offspring. Clin Endocrinol (Oxf) 2014;80:804-10.