-
1
-
-
0035897696
-
Expert panel on detection, evaluation and treatment of high blood cholesterol in adults - Executive summary of the third report of the national cholesterol education programme (NCEP). Expert panel on detection, evaluation and treatment of high blood cholesterol in adults (Adult treatment panel III)
-
Expert panel on detection, evaluation and treatment of high blood cholesterol in adults - executive summary of the third report of the national cholesterol education programme (NCEP). Expert panel on detection, evaluation and treatment of high blood cholesterol in adults (Adult treatment panel III) J Am Med Ass 285 2001 2486 2497
-
(2001)
J Am Med Ass
, vol.285
, pp. 2486-2497
-
-
-
2
-
-
2542461241
-
Optimal low density lipoprotein is 50-70 mg/dl; Lower the better and physiologically normal
-
J.H. O' Keefe Jr., L. Cordain, W.H. Harris, R.M. Moe, and R. Vogel Optimal low density lipoprotein is 50-70 mg/dl; lower the better and physiologically normal J Am Coll Cardiol 43 2004 2142 2146
-
(2004)
J Am Coll Cardiol
, vol.43
, pp. 2142-2146
-
-
O'Keefe, J.H.1
Cordain, L.2
Harris, W.H.3
Moe, R.M.4
Vogel, R.5
-
3
-
-
78449281377
-
Efficacy and safety of more intensive lowering of LDL cholesterol: A meta analysis of data from 170,000 participants in 26 randomized trials
-
C. Baigent, L. Blackwell, J. Emberson, et al. for the Cholesterol Treatment Trialist (CTT) Efficacy and safety of more intensive lowering of LDL cholesterol: a meta analysis of data from 170,000 participants in 26 randomized trials Lancet 376 2010 1670 1681
-
(2010)
Lancet
, vol.376
, pp. 1670-1681
-
-
Cholesterol Treatment Trialist (CTT)1
Baigent, C.2
Blackwell, L.3
Emberson, J.4
-
5
-
-
84902576469
-
2013 ACC/AHA guidelines on treatment of blood cholesterol to reduce atherosclerotic cardiovascular risk in adults
-
N.J. Stone, J.G. Robinson, A.H. Lichtenstein, and et al. 2013 ACC/AHA guidelines on treatment of blood cholesterol to reduce atherosclerotic cardiovascular risk in adults J Am Coll Cardiol 63 2014 2889 2934
-
(2014)
J Am Coll Cardiol
, vol.63
, pp. 2889-2934
-
-
Stone, N.J.1
Robinson, J.G.2
Lichtenstein, A.H.3
-
6
-
-
84903165096
-
2013 ACC/AHA guidelines on the assessment of cardiovascular risk: A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines
-
D.C. Goff Jr., D.M. Lloyd-Jones, G. Bennet, and et al. 2013 ACC/AHA guidelines on the assessment of cardiovascular risk: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines J Am Coll Cardiol 63 2014 2935 2959
-
(2014)
J Am Coll Cardiol
, vol.63
, pp. 2935-2959
-
-
Goff, D.C.1
Lloyd-Jones, D.M.2
Bennet, G.3
-
8
-
-
79960205374
-
ESC/EAS guidelines for the management of dyslipidaemias: The Task Force for the management of dsylipidaemias for the European Society of Cardiology (ESC) and the European Atherosclerosis Society (EAS)
-
A.L. Catapano, Z. Reiner, G. De Backer, and et al. ESC/EAS guidelines for the management of dyslipidaemias: the Task Force for the management of dsylipidaemias for the European Society of Cardiology (ESC) and the European Atherosclerosis Society (EAS) Atherosclerosis 217 2011 3 46
-
(2011)
Atherosclerosis
, vol.217
, pp. 3-46
-
-
Catapano, A.L.1
Reiner, Z.2
De Backer, G.3
-
9
-
-
84872712625
-
2012 update of the Canadian Cardiovascular Society guidelines for the diagnosis and treatment of dyslipidaemia for the prevention of cardiovascular disease in adults
-
T.J. Anderson, J. Greogoire, R.A. Hegele, and et al. 2012 update of the Canadian Cardiovascular Society guidelines for the diagnosis and treatment of dyslipidaemia for the prevention of cardiovascular disease in adults Can J Cardiol 29 2013 151 167
-
(2013)
Can J Cardiol
, vol.29
, pp. 151-167
-
-
Anderson, T.J.1
Greogoire, J.2
Hegele, R.A.3
-
10
-
-
84902603181
-
2013 ACC/AHA cholesterol treatment guidelines. What was done well and what could be done better
-
S.S. Martin, T.T. Abd, S.R. Jones, and et al. 2013 ACC/AHA cholesterol treatment guidelines. What was done well and what could be done better J Am Coll Cardiol 63 2014 2674 2678
-
(2014)
J Am Coll Cardiol
, vol.63
, pp. 2674-2678
-
-
Martin, S.S.1
Abd, T.T.2
Jones, S.R.3
-
11
-
-
84893842113
-
Statins, risk assessment and the new American prevention guidelines
-
D.M. Lloyd Jones, D. Goff, and N.J. Stone Statins, risk assessment and the new American prevention guidelines Lancet 383 2014 600 602
-
(2014)
Lancet
, vol.383
, pp. 600-602
-
-
Lloyd Jones, D.M.1
Goff, D.2
Stone, N.J.3
-
12
-
-
84921670737
-
Implications of the 2013 ACC/AHA cholesterol guidelines for adults in contemporary cardiovascular practice - Insight from the NCDR Pinnacle registry
-
T.M. Maddox, W.B. Borden, F.T. Tang, and et al. Implications of the 2013 ACC/AHA cholesterol guidelines for adults in contemporary cardiovascular practice - insight from the NCDR Pinnacle registry J Am Coll Cardiol 64 2014 2183 2195
-
(2014)
J Am Coll Cardiol
, vol.64
, pp. 2183-2195
-
-
Maddox, T.M.1
Borden, W.B.2
Tang, F.T.3
-
13
-
-
84920838913
-
Consensus statement on management of dyslipidemia in Indian subjects
-
K. Sarat Chandra, M. Bansal, T. Nair, and et al. Consensus statement on management of dyslipidemia in Indian subjects Indian Heart J 66 suppl 3 2014 S1 S51
-
(2014)
Indian Heart J
, vol.66
, pp. S1-S51
-
-
Sarat Chandra, K.1
Bansal, M.2
Nair, T.3
-
14
-
-
84892649479
-
Standards of medical care in diabetes
-
Standards of medical care in diabetes Diabetes Care 37 2014 S14 S80
-
(2014)
Diabetes Care
, vol.37
, pp. S14-S80
-
-
-
15
-
-
34248654864
-
Comparison of rosuvastatin versus atorvastatin in south Asian patients at risk of coronary artery disease
-
P.C. Deedwania, M. Gupta, M. Stein, J. Ycas, and A. Gold Comparison of rosuvastatin versus atorvastatin in south Asian patients at risk of coronary artery disease Am J Cardiol 99 2007 1538 1543
-
(2007)
Am J Cardiol
, vol.99
, pp. 1538-1543
-
-
Deedwania, P.C.1
Gupta, M.2
Stein, M.3
Ycas, J.4
Gold, A.5
-
16
-
-
33749015458
-
Acute coronary syndromes and Diabetes: Is intensive lipid lowering, beneficial? Result of the PROVE IT - TIMI 22 Trial
-
S. Ahmed, G.P. Cannon, S.A. Murphy, and et al. Acute coronary syndromes and Diabetes: is intensive lipid lowering, beneficial? Result of the PROVE IT - TIMI 22 Trial Eur Heart J 27 2006 2323 2329
-
(2006)
Eur Heart J
, vol.27
, pp. 2323-2329
-
-
Ahmed, S.1
Cannon, G.P.2
Murphy, S.A.3
-
17
-
-
84855171302
-
Niacin in patients with low HDL cholesterol levels receiving intensive statin therapy
-
AIM HIGH Investigators
-
AIM HIGH Investigators W.E. Boden, and J.L. Probstfeld Niacin in patients with low HDL cholesterol levels receiving intensive statin therapy New Engl J Med 365 2011 2255 2267
-
(2011)
New Engl J Med
, vol.365
, pp. 2255-2267
-
-
Boden, W.E.1
Probstfeld, J.L.2
-
18
-
-
84886070404
-
Relationship of Apo lipoprotein A-1 and B, and Lipoprotein (a) to cardiovascular outcomes. the AIM HIGH TRIAL (Atherosclerosis Intervention in Metabolic Syndrome with Low HDL/High Triglyceride and Impact on Global Health Outcomes)
-
J.J. Albers, A. Slee, K.D. O'Brien, and et al. Relationship of Apo lipoprotein A-1 and B, and Lipoprotein (a) to cardiovascular outcomes. The AIM HIGH TRIAL (Atherosclerosis Intervention in Metabolic Syndrome with Low HDL/High Triglyceride and Impact on Global Health Outcomes) J Am Coll Cardiol 62 2013 1575 1579
-
(2013)
J Am Coll Cardiol
, vol.62
, pp. 1575-1579
-
-
Albers, J.J.1
Slee, A.2
O'Brien, K.D.3
-
19
-
-
84942837704
-
-
Improved Reduction of Outcome: Vytorin Efficacy International Trial Presented by Dr. Christopher Cannon at AHA Scientific Session Nov 17, 2014.
-
Improved Reduction of Outcome: Vytorin Efficacy International Trial Presented by Dr. Christopher Cannon at AHA Scientific Session Nov 17, 2014.
-
-
-
-
20
-
-
84871945617
-
Efficacy and safety of microsomal triglyceride transfer protein inhibitor in patients with homozygous familial hypercholesterolemia: A single arm, open label phase 3 study
-
M. Cuchel, E.A. Meagher, H. du Toit Theron, and et al. Efficacy and safety of microsomal triglyceride transfer protein inhibitor in patients with homozygous familial hypercholesterolemia: a single arm, open label phase 3 study Lancet 381 2013 40 46
-
(2013)
Lancet
, vol.381
, pp. 40-46
-
-
Cuchel, M.1
Meagher, E.A.2
Du Toit Theron, H.3
-
21
-
-
84888090979
-
Mipomersen an apoprotein B synthesis inhibitor reduces atherogenic lipoproteins in patients with severe hypercholesterolemia at high cardiovascular risk - A randomized, double blind, placebo controlled trial
-
G.S. Thomas, W.C. Cromwell, S. Alis, W. Chin, I.D. Flaim, and M. Davidson Mipomersen an apoprotein B synthesis inhibitor reduces atherogenic lipoproteins in patients with severe hypercholesterolemia at high cardiovascular risk - a randomized, double blind, placebo controlled trial J Am Coll Cardiol 62 2013 2178 2184
-
(2013)
J Am Coll Cardiol
, vol.62
, pp. 2178-2184
-
-
Thomas, G.S.1
Cromwell, W.C.2
Alis, S.3
Chin, W.4
Flaim, I.D.5
Davidson, M.6
-
22
-
-
0037603589
-
Mutations in PCSK 9 causes autosomal dominant hypercholestermia
-
M. Abifadel, M. Varret, J.P. Rabes, and et al. Mutations in PCSK 9 causes autosomal dominant hypercholestermia Nat Genet 34 2003 154 156
-
(2003)
Nat Genet
, vol.34
, pp. 154-156
-
-
Abifadel, M.1
Varret, M.2
Rabes, J.P.3
-
23
-
-
84902096056
-
Elevated plasma PCSK 9 levels are equally detrimental for patients with non familial hypercholestremia and heterozygous familial hypercholesterolemia irrespective of low density lipoprotein receptor defects
-
G. Lambert, F. Petrides, M. Chatelais, and et al. Elevated plasma PCSK 9 levels are equally detrimental for patients with non familial hypercholestremia and heterozygous familial hypercholesterolemia irrespective of low density lipoprotein receptor defects J Am Coll Cardiol 63 2014 2365 2375
-
(2014)
J Am Coll Cardiol
, vol.63
, pp. 2365-2375
-
-
Lambert, G.1
Petrides, F.2
Chatelais, M.3
-
24
-
-
84885447918
-
Targeting the Proprotein Convertase Subtilisin/Kexin Type 9 for treatment of dyslipidemia and atherosclerosis
-
D. Urban, J. Poss, M. Bohn, and S. Lauf Targeting the Proprotein Convertase Subtilisin/Kexin Type 9 for treatment of dyslipidemia and atherosclerosis J Am Coll Cardiol 62 2013 1401 1408
-
(2013)
J Am Coll Cardiol
, vol.62
, pp. 1401-1408
-
-
Urban, D.1
Poss, J.2
Bohn, M.3
Lauf, S.4
-
25
-
-
84925351969
-
Lipid lowering with PCSK 9 inhibitors
-
Razvan T. Dadu, and Chrislie Ballantyne Lipid lowering with PCSK 9 inhibitors Nat Rev Cardiol 11 2014 563 575
-
(2014)
Nat Rev Cardiol
, vol.11
, pp. 563-575
-
-
Dadu, R.T.1
Ballantyne, C.2
-
27
-
-
84870494510
-
Efficacy, safety and tolerability of monoclonal antibody to proprotein convertase subtilisin/Kexin type 9 as monotherapy in patients with hypercholesterolemia (MENDEL): A randomized, double blind, placebo controlled, phase 2 study
-
M.J. Koren, R. Scott, J.B. Kin, and et al. Efficacy, safety and tolerability of monoclonal antibody to proprotein convertase subtilisin/Kexin type 9 as monotherapy in patients with hypercholesterolemia (MENDEL): a randomized, double blind, placebo controlled, phase 2 study Lancet 380 2012 1995 2006
-
(2012)
Lancet
, vol.380
, pp. 1995-2006
-
-
Koren, M.J.1
Scott, R.2
Kin, J.B.3
-
28
-
-
84869220345
-
Low density lipoprotein cholesterol lowering effect of AMG 145, a monoclonal antibody to proprotein convertase subtilisin/Kexin type 9 serine proteases in patients with heterozygous familial hypercholesterolemia: The Reduction of LDLc with PCSK 9 inhibitors in Heterozygous Familial Hypercholesterolemia Disorder (RUTHERFORD) randomized trial
-
F. Raal, R. Scott, R. Somaratne, and et al. Low density lipoprotein cholesterol lowering effect of AMG 145, a monoclonal antibody to proprotein convertase subtilisin/Kexin type 9 serine proteases in patients with heterozygous familial hypercholesterolemia: the Reduction of LDLc with PCSK 9 inhibitors in Heterozygous Familial Hypercholesterolemia Disorder (RUTHERFORD) randomized trial Circulation 126 2012 2408 2417
-
(2012)
Circulation
, vol.126
, pp. 2408-2417
-
-
Raal, F.1
Scott, R.2
Somaratne, R.3
-
29
-
-
84871326497
-
Effects of a monoclonal antibody to PCSK 9 on low density lipoprotein cholesterol levels in statin intolerant patients: The GAUSS randomized trial
-
D. Sullivan, A.G. Olsson, R. Scott, and et al. Effects of a monoclonal antibody to PCSK 9 on low density lipoprotein cholesterol levels in statin intolerant patients: the GAUSS randomized trial J Am Med Ass 308 2012 2497 2506
-
(2012)
J Am Med Ass
, vol.308
, pp. 2497-2506
-
-
Sullivan, D.1
Olsson, A.G.2
Scott, R.3
-
30
-
-
84902142901
-
Anti PCSK 9 monotherapy for hypercholesterolemia - The MANDEL 2, randomized, controlled phase III clinical trial of evolocumab
-
M.J. Koren, P. Lundqvist, M. Blognese, and et al. Anti PCSK 9 monotherapy for hypercholesterolemia - the MANDEL 2, randomized, controlled phase III clinical trial of evolocumab J Am Coll Cardiol 63 2014 2531 2540
-
(2014)
J Am Coll Cardiol
, vol.63
, pp. 2531-2540
-
-
Koren, M.J.1
Lundqvist, P.2
Blognese, M.3
-
31
-
-
84902157271
-
Anti PCSK 9 antibody effectively lowers cholesterol in patients with statin intolerance: The GAUSS 2 randomized, placebo controlled phase 3 clinical trial of evolocumab
-
E. Stroes, D. Colquhoun, D. Sullivan, and et al. Anti PCSK 9 antibody effectively lowers cholesterol in patients with statin intolerance: the GAUSS 2 randomized, placebo controlled phase 3 clinical trial of evolocumab J Am Coll Cardiol 63 2014 2541 2548
-
(2014)
J Am Coll Cardiol
, vol.63
, pp. 2541-2548
-
-
Stroes, E.1
Colquhoun, D.2
Sullivan, D.3
-
32
-
-
84883232230
-
AMG 145, a monoclonal antibody against proprotein convertase subtilisin kexin 9 significantly reduces lipoprotein (a) in hypercholesterolemia patients receiving statin therapy: An analysis from the LDL Assessment with Proprotein Convertase Subtilisin Kexin Type 9 Monoclonal Antibody Inhibition Combined with Statin Therapy (LAPLACE) Thrombolysis in Myocardial Infarction TIMI 57 trial
-
N.R. Desai, P. Kohli, R.P. Giugliano, and et al. AMG 145, a monoclonal antibody against proprotein convertase subtilisin kexin 9 significantly reduces lipoprotein (a) in hypercholesterolemia patients receiving statin therapy: an analysis from the LDL Assessment with Proprotein Convertase Subtilisin Kexin Type 9 Monoclonal Antibody Inhibition Combined with Statin Therapy (LAPLACE) Thrombolysis in Myocardial Infarction TIMI 57 trial Circulation 128 2013 962 969
-
(2013)
Circulation
, vol.128
, pp. 962-969
-
-
Desai, N.R.1
Kohli, P.2
Giugliano, R.P.3
-
33
-
-
84892679366
-
Efficacy and safety of longer term administration of evolocumab (AMC 145) in patients with hypercholesterolemia: 52 weeks results from the open label study of Long Term Evaluation against LDLc (OSLER) randomized trial
-
M.J. Koren, R.P. Giugliono, F. Raas, and et al. Efficacy and safety of longer term administration of evolocumab (AMC 145) in patients with hypercholesterolemia: 52 weeks results from the open label study of Long Term Evaluation against LDLc (OSLER) randomized trial Circulation 129 2014 234 243
-
(2014)
Circulation
, vol.129
, pp. 234-243
-
-
Koren, M.J.1
Giugliono, R.P.2
Raas, F.3
-
34
-
-
84897471477
-
Reduction in lipoprotein (a) with PCSK 9 monoclonal antibody evolocumab (AMG 145)
-
J.J. Raal, R.P. Giugliano, M.S. Sabatine, and et al. Reduction in lipoprotein (a) with PCSK 9 monoclonal antibody evolocumab (AMG 145) J Am Coll Cardiol 63 2014 1278 1288
-
(2014)
J Am Coll Cardiol
, vol.63
, pp. 1278-1288
-
-
Raal, J.J.1
Giugliano, R.P.2
Sabatine, M.S.3
-
35
-
-
84887164358
-
Effects of the lipoprotein convertase subtilisin/Kexin 9 monoclonal antibody AMG 145 in homozygous familial hypercholestermia
-
E.A. Stein, N. Honarpour, S.M. Wasserman, F. Xu, R. Scott, and J.J. Raal Effects of the lipoprotein convertase subtilisin/Kexin 9 monoclonal antibody AMG 145 in homozygous familial hypercholestermia Circulation 128 2013 2113 2120
-
(2013)
Circulation
, vol.128
, pp. 2113-2120
-
-
Stein, E.A.1
Honarpour, N.2
Wasserman, S.M.3
Xu, F.4
Scott, R.5
Raal, J.J.6
-
36
-
-
84863494422
-
Effects of a monoclonal antibody to PCSK 9 Reg N 727/SAR 236553 to reduce low density lipoprotein cholesterol in patients with heterozygous familial hypercholestremia on stable statin dose with or without ezetimibe therapy: A phase 2 randomized controlled trial
-
E.A. Stein, D. Gipe, J. Bergeron, and et al. Effects of a monoclonal antibody to PCSK 9 Reg N 727/SAR 236553 to reduce low density lipoprotein cholesterol in patients with heterozygous familial hypercholestremia on stable statin dose with or without ezetimibe therapy: a phase 2 randomized controlled trial Lancet 380 2012 29 36
-
(2012)
Lancet
, vol.380
, pp. 29-36
-
-
Stein, E.A.1
Gipe, D.2
Bergeron, J.3
-
37
-
-
84868689211
-
Atorvastatin with without an antibody to PCKS 9 in primary hypercholesterolemia
-
E.M. Roth, J.M. McKenny, C. Hanotin, G. Asset, and E.A. Stein Atorvastatin with without an antibody to PCKS 9 in primary hypercholesterolemia New Engl J Med 367 2012 1891 1900
-
(2012)
New Engl J Med
, vol.367
, pp. 1891-1900
-
-
Roth, E.M.1
McKenny, J.M.2
Hanotin, C.3
Asset, G.4
Stein, E.A.5
-
38
-
-
84862219022
-
Safety and efficacy of a monoclonal antibody to proprotein convertase subtilisin/Kexin type 9 serine protease SAR 236553/REG 727 in patients with primary hypercholesterolemia receiving ongoing stable atorvastatin therapy
-
J.M. McKeeny, M.J. Koren, D.J. Keveiakes, C. Flanotin, X.C. Ferrand, and E.A. Stein Safety and efficacy of a monoclonal antibody to proprotein convertase subtilisin/Kexin type 9 serine protease SAR 236553/REG 727 in patients with primary hypercholesterolemia receiving ongoing stable atorvastatin therapy J Am Coll Cardiol 59 2012 2344 2353
-
(2012)
J Am Coll Cardiol
, vol.59
, pp. 2344-2353
-
-
McKeeny, J.M.1
Koren, M.J.2
Keveiakes, D.J.3
Flanotin, C.4
Ferrand, X.C.5
Stein, E.A.6
-
39
-
-
84942839215
-
Odyssey long term trial with alirocumab
-
Available at
-
J. Robinson Odyssey long term trial with alirocumab Presented at AHA Nov 2014 2014 Available at: www.esccardio.org
-
(2014)
Presented at AHA Nov 2014
-
-
Robinson, J.1
|