Synthesis of dual-functional targeting probes for cancer theranostics based on iron oxide nanoparticles coated by centipede-like polymer connected with pH-responsive anticancer drug

Journal of Biomaterials Science, Polymer Edition

Volumn 26, Issue 16, 2015, Pages 1178-1189

  Zhao, Haochen ^a   Li, Zhiping ^a   Yang, Bohan ^b   Wang, Jingyuan ^a   Li, Yapeng ^a  

^a JILIN UNIVERSITY   (China)

^b BEIJING INSTITUTE OF SPACECRAFT SYSTEM ENGINEERING   (China)

Author keywords

bortezomib; cancer treatment; magnetic resonance imaging; pH responsive; targeting imaging

Indexed keywords

BIOCOMPATIBILITY; CELL ENGINEERING; DIAGNOSIS; DISEASES; IRON OXIDES; MAGNETIC RESONANCE IMAGING; METAL NANOPARTICLES; NANOPARTICLES; ONCOLOGY; POLYETHYLENE GLYCOLS; PROBES; SYNTHESIS (CHEMICAL);

ANTI-VASCULAR ENDOTHELIAL GROWTH FACTORS; BORTEZOMIB; IRON OXIDE NANOPARTICLE; PH-RESPONSIVE; SUPERPARAMAGNETIC IRON OXIDE NANOPARTICLES; TARGETING CAPABILITY; TARGETING MOLECULES; VASCULAR ENDOTHELIAL GROWTH FACTOR;

ENDOTHELIAL CELLS;

BORTEZOMIB; DODECYLAMINE; MACROGOL; POLYMER; SUPERPARAMAGNETIC IRON OXIDE NANOPARTICLE; ULTRASMALL SUPERPARAMAGNETIC IRON OXIDE; VASCULOTROPIN; AMINE; ANTINEOPLASTIC AGENT; DELAYED RELEASE FORMULATION; IMMOBILIZED ANTIBODY; ITACONIC ACID; MACROGOL DERIVATIVE; MAGNETITE NANOPARTICLE; RECOMBINANT PROTEIN; SUCCINIC ACID DERIVATIVE; VASCULOTROPIN A;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER CELL; CARBON NUCLEAR MAGNETIC RESONANCE; CELL CULTURE; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG RELEASE; DRUG SYNTHESIS; DRUG TARGETING; ENDOCYTOSIS; HUMAN; HUMAN CELL; MALE; MOLECULAR WEIGHT; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PH; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; TARGET CELL; ABSORPTION; ADMINISTRATION AND DOSAGE; ANIMAL; ANTAGONISTS AND INHIBITORS; CELL SURVIVAL; CHEMISTRY; COMPARATIVE STUDY; DELAYED RELEASE FORMULATION; DRUG DELIVERY SYSTEM; DRUG EFFECTS; GENETICS; HEPG2 CELL LINE; INSTITUTE FOR CANCER RESEARCH MOUSE; LIVER CELL; LIVER NEOPLASMS, EXPERIMENTAL; METABOLISM; PATHOLOGY; PHARMACOKINETICS; PHARMACOLOGY; PROCEDURES; SURFACE PROPERTY; THERANOSTIC NANOMEDICINE; TISSUE DISTRIBUTION; ULTRASTRUCTURE;

ABSORPTION, PHYSIOLOGICAL; AMINES; ANIMALS; ANTIBODIES, IMMOBILIZED; ANTINEOPLASTIC AGENTS; BORTEZOMIB; CELL SURVIVAL; DELAYED-ACTION PREPARATIONS; DRUG DELIVERY SYSTEMS; DRUG LIBERATION; HEP G2 CELLS; HEPATOCYTES; HUMANS; HYDROGEN-ION CONCENTRATION; LIVER NEOPLASMS, EXPERIMENTAL; MAGNETITE NANOPARTICLES; MALE; MICE, INBRED ICR; POLYETHYLENE GLYCOLS; RECOMBINANT PROTEINS; SUCCINATES; SURFACE PROPERTIES; THERANOSTIC NANOMEDICINE; TISSUE DISTRIBUTION; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 84942830310     PISSN: 09205063     EISSN: 15685624     Source Type: Journal    
DOI: 10.1080/09205063.2015.1080900     Document Type: Article

References (29)

1. Laurent S, Forge D, Port M, et al. Magnetic iron oxide nanoparticles: synthesis, stabilization, vectorization, physicochemical characterizations, and biological applications. Chem. Rev. 2008;108:2064-2110.
2. Wu X, He X, Zhong L, et al. Water-soluble dendritic-linear triblock copolymer-modified magnetic nanoparticles: preparation, characterization and drug release properties. J. Mater. Chem. 2011;21:13611-13620.
3. Gijs MAM, Lacharme FDR, Lehmann U. Microfluidic applications of magnetic particles for biological analysis and catalysis. Chem. Rev. 2010;110:1518-1563.
4. Frey NA, Peng S, Cheng K, et al. Magnetic nanoparticles: synthesis, functionalization, and applications in bioimaging and magnetic energy storage. Chem. Soc. Rev. 2009;38: 2532-2542.
5. Huang H, Remsen EE, Kowalewski T, et al. Nanocages derived from shell cross-linked micelle templates. J. Am. Chem. Soc. 1999;121:3805-3806.
6. Gref R, Minamitake Y, Peracchia MT, et al. Biodegradable long-circulating polymeric nanospheres. Science. 1994;263:1600-1603.
7. Farokhzad OC, Cheng J, Teply BA, et al. Targeted nanoparticle-Aptamer bioconjugates for cancer chemotherapy in vivo. Proc. Nat. Acad. Sci. USA. 2006;103:6315-6320.
8. Lee H, Lee E, Kim DK, et al. Antibiofouling polymer-coated superparamagnetic iron oxide nanoparticles as potential magnetic resonance contrast agents for in vivo cancer imaging. J. Am. Chem. Soc. 2006;128:7383-7389.
9. Yang J, Lee T, Lee J, et al. Synthesis of ultrasensitive magnetic resonance contrast agents for cancer imaging using PEG-fatty acid. Chem. Mater. 2007;19:3870-3876.
10. Laginha KM, Verwoert S, Charrois GJR, et al. Determination of doxorubicin levels in whole tumor and tumor nuclei in murine breast cancer tumors. Clin. Cancer Res. 2005;11: 6944-6949.
11. Aryal S, Grailer JJ, Steeber SPDA, et al. Doxorubicin conjugated gold nanoparticles as water-soluble and pH-responsive anticancer drug nanocarriers. J. Mater. Chem. 2009;19:7879-7884.
12. Frederick CA, Williams LD, Ughetto G, et al. Structural comparison of anticancer drug-DNA complexes: adriamycin and daunomycin. Biochemistry. 1990;29:2538-2549.
13. Etrych T, Jelnková M, hová B, et al. New HPMA copolymers containing doxorubicin bound via pH-sensitive linkage: synthesis and preliminary in vitro and in vivo biological properties. J. Control. Release. 2001;73:89-102.
14. Weiss AJ, Manthel RW. Experience with the use of adriamycin in combination with other anticancer agents using a weekly schedule, with particular reference to lack of cardiac toxicity. Cancer. 1977;40:2046-2052.
15. Nasongkla N, Bey E, Ren J, et al. Multifunctional polymeric micelles as cancer-targeted, MRI-ultrasensitive drug delivery systems. Nano Lett. 2006;6:2427-2430.
16. Kohler N, Sun C, Fichtenholtz A, et al. Methotrexate-immobilized poly(ethylene glycol) magnetic nanoparticles for MR imaging and drug delivery. Small. 2006;2:785-792.
17. Lanthong P, Nuisin R, Kiatkamjornwong S. Graft copolymerization, characterization, and degradation of cassava starch-g-Acrylamide/itaconic acid superabsorbents. Carbohydr. Polym. 2006;66:229-245.
18. Yang B, Li Y, Sun X, et al. A pH-responsive drug release system based on doxorubicin conjugated amphiphilic polymer coated quantum dots for tumor cell targeting and tracking. J. Chem. Technol. Biotechnol. 2013;88:2169.
19. Mrkvan T, Sirova M, Etrych T, et al. Chemotherapy based on HPMA copolymer conjugates with pH-controlled release of doxorubicin triggers anti-tumor immunity. J. Controlled Release. 2005;110:119-129.
20. Pechar M, Braunova A, Ulbrich K, et al. Poly(ethylene glycol)-doxorubicin conjugates with pH-controlled activation. J. Bioact. Compat. Polym. 2005;20:319-341.
21. Rodrigues PCA, Roth T, Fiebig HH, et al. Correlation of the acid-sensitivity of polyethylene glycol daunorubicin conjugates with their in vitro antiproliferative activity. Bioorg. Med. Chem. 2006;14:4110-4117.
22. Ulbrich K, Subr V. Polymeric anticancer drugs with pH-controlled activation. Adv. Drug Delivery Rev. 2004;56:1023-1050.
23. Weissleder R, Lee AS, Fischman AJ, et al. Polyclonal human immunoglobulin G labeled with polymeric iron oxide: antibody MR imaging. Radiology. 1991;181:245-249.
24. Bulte JWM, Kraitchman DL. Iron oxide MR contrast agents for molecular and cellular imaging. NMR Biomed. 2004;17:484-499.
25. Elcin YM, Dixit V, Gitnick G. Extensive in vivo angiogenesis following controlled release of human vascular endothelial cell growth factor: implications for tissue engineering and wound healing. Artif. Organs. 2001;25:558-565.
26. Lee Y, Park SY, Mok H, et al. Synthesis, characterization, antitumor activity of pluronic mimicking copolymer micelles conjugated with doxorubicin via acid-cleavable linkage. Bioconjugate Chem. 2008;19:525-531.
27. Chandra S, Mehta S, Nigam S, et al. Dendritic magnetite nanocarriers for drug delivery applications. New J. Chem. 2010;34:648-655.
28. Higuchi Y, Kawakami S, Hashida M. Strategies for in vivo delivery of siRNAs. BioDrugs. 2010;24:195-205.
29. Kawakami S, Higuchi Y, Hashida M. Nonviral approaches for targeted delivery of plasmid DNA and oligonucleotide. J. Pharm. Sci. 2008;97:726-745.