Barriers and facilitators to starting insulin in patients with type 2 diabetes: A systematic review

International Journal of Clinical Practice

Volumn 69, Issue 10, 2015, Pages 1050-1070

  Ng, C J ^a   Lai, P S M ^a   Lee, Y K ^a   Azmi, S A ^a   Teo, C H ^a  

^a UNIVERSITY OF MALAYA   (Malaysia)

Author keywords

[No Author keywords available]

Indexed keywords

INSULIN; ANTIDIABETIC AGENT;

ADVERSE DRUG REACTION; ATTITUDE TO HEALTH; DRUG COST; FEAR; HEALTH CARE PRACTICE; HEALTHCARE PROFESSIONAL FACTOR; HUMAN; HYPOGLYCEMIA; INJECTION SITE PAIN; INSULIN INITIATION; INSULIN TREATMENT; INTERRATER RELIABILITY; LANGUAGE BARRIER; NON INSULIN DEPENDENT DIABETES MELLITUS; PATIENT ATTITUDE; PATIENT COUNSELING; PATIENT EDUCATION; PATIENT INFORMATION; PATIENT PREFERENCE; PATIENT RELATED FACTOR; PRIORITY JOURNAL; PROFESSIONAL COMPETENCE; QUALITATIVE RESEARCH; QUALITY CONTROL; QUANTITATIVE STUDY; REVIEW; RISK BENEFIT ANALYSIS; RISK FACTOR; SKILL; SOCIAL ASPECT; SOCIAL DISCRIMINATION; SOCIAL STIGMA; SYSTEM FACTOR; SYSTEMATIC REVIEW; TIME; WEIGHT GAIN; DECISION MAKING; DIABETES MELLITUS, TYPE 2; PATIENT COMPLIANCE; TIME TO TREATMENT; UTILIZATION;

DECISION MAKING; DIABETES MELLITUS, TYPE 2; HUMANS; HYPOGLYCEMIC AGENTS; INSULIN; PATIENT COMPLIANCE; TIME-TO-TREATMENT;

EID: 84942820755     PISSN: 13685031     EISSN: 17421241     Source Type: Journal    
DOI: 10.1111/ijcp.12691     Document Type: Review

References (40)

1. UK Prospective Diabetes Study (UKPDS) Group. Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). Lancet 1998; 352 (9131): 837-53.
2. Peyrot M, Rubin RR, Lauritzen T, et al., Resistance to insulin therapy among patients and providers: results of the cross-national Diabetes Attitudes, Wishes, and Needs (DAWN) study. Diabetes Care 2005; 28 (11): 2673-9.
3. Larkin ME, Capasso VA, Chen CL, et al., Measuring psychological insulin resistance: barriers to insulin use. Diabetes Educ 2008; 34 (3): 511-7.
4. Polonsky W,. Psychological insulin resistance: the patient perspective. Diabetes Educ 2007; 33 (Suppl. 7): 241S-4S.
5. Korytkowski M,. When oral agents fail: practical barriers to starting insulin. Int J Obes Relat Metab Disord 2002; 26 (Suppl. 3): S18-24.
6. Polonsky WH, Jackson RA,. What's so tough about taking insulin? Addressing the problem of psychological insulin resistance in type 2 diabetes. Clin Diabetes 2004; 22 (3): 147-50.
7. Nam S, Chesla C, Stotts NA, Kroon L, Janson SL,. Factors associated with psychological insulin resistance in individuals with type 2 diabetes. Diabetes Care [Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't] 2010; 33 (8): 1747-9.
8. Skyler JS, Bergenstal R, Bonow RO, et al., Intensive glycemic control and the prevention of cardiovascular events: implications of the ACCORD, ADVANCE, and VA diabetes trials: a position statement of the American Diabetes Association and a scientific statement of the American College of Cardiology Foundation and the American Heart Association. Diabetes Care 2009; 32 (1): 187-92.
9. Kmet LM, Lee RC, Cook LS,. Standard quality assessment criteria for evaluating primary research papers from a variety of fields. Alberta Heritage Foundation for Medical Research [serial on the Internet]. 2004.
10. Greaves CJ, Brown P, Terry RT, Eiser C, Lings P, Stead JW,. Converting to insulin in primary care: an exploration of the needs of practice nurses. J Adv Nurs 2003; 42 (5): 487-96.
11. Jenkins N, Hallowell N, Farmer AJ, Holman RR, Lawton J,. Initiating insulin as part of the treating to target in type 2 diabetes (4-T) trial: an interview study of patients' and health professionals' experiences. Diabetes Care 2010; 33 (10): 2178-80.
12. Khan H, Lasker SS, Chowdhury TA,. Prevalence and reasons for insulin refusal in Bangladeshi patients with poorly controlled type 2 diabetes in East London. Diabet Med 2008; 25 (9): 1108-11.
13. Patel N, Stone MA, Chauhan A, Davies MJ, Khunti K,. Insulin initiation and management in people with type 2 diabetes in an ethnically diverse population: the healthcare provider perspective. Diabet Med 2012; 29 (10): 1311-6.
14. Sigurdardottir AK,. Nurse specialists' perceptions of their role and function in relation to starting an adult diabetic on insulin. J Clin Nurs 1999; 8 (5): 512-8.
15. Phillips A,. Starting patients on insulin therapy: diabetes nurse specialist views. Nurs Stand 2007; 21 (30): 35-40.
16. Jeavons D, Hungin APS, Cornford CS,. Patients with poorly controlled diabetes in primary care: healthcare clinicians' beliefs and attitudes. Postgrad Med J 2006; 82 (967): 347-50.
17. Hayes RP, Fitzgerald JT, Jacober SJ,. Primary care physician beliefs about insulin initiation in patients with type 2 diabetes. Int J Clin Pract 2008; 62 (6): 860-8.
18. Karter AJ, Subramanian U, Saha C, et al., Barriers to insulin initiation: the translating research into action for diabetes insulin starts project. Diabetes Care 2010; 33 (4): 733-5.
19. Ratanawongsa N, Crosson JC, Schillinger D, Karter AJ, Saha CK, Marrero DG,. Getting under the skin of clinical inertia in insulin initiation The Translating Research Into Action for Diabetes (TRIAD) Insulin Starts Project. Diabetes Educ 2012; 38 (1): 94-100.
20. Hassali MA, Ching MW, Yusoff ZM, et al., 'Why I do not want to take insulin shots': findings from a qualitative study among diabetic patients in Malaysia. J Pub Health (Germany) 2014; 22 (1): 3-11.
21. Lee YK, Lee PY, Ng CJ,. A qualitative study on healthcare professionals' perceived barriers to insulin initiation in a multi-ethnic population. BMC Fam Pract 2012; 13: 28.
22. Tan AM, Muthusamy L, Ng CC, Phoon KY, Ow JH, Tan NC,. Initiation of insulin for type 2 diabetes mellitus patients: what are the issues? A qualitative study. Singapore Med J 2011; 52 (11): 801-9.
23. Tan NC, Tan AM, Yeo JP,; Rethink Study Group. RETHINK: an observational cross sectional study on the uptake of insulin therapy among type 2 diabetes patients with secondary drug failure treated in primary care. Asia Pac Fam Med 2003; 2 (3): 157-65.
24. Nadasen DM, Naidoo M,. Patients with type 2 diabetes and difficulties associated with initiation of insulin therapy in a public health clinic in Durban. S Afr Fam Pract 2012; 54 (5): 436-40.
25. Haque M, Emerson SH, Dennison CR, Navsa M, Levitt NS,. Barriers to initiating insulin therapy in patients with type 2 diabetes mellitus in public-sector primary health care centres in Cape Town. S Afr Med J 2005; 95 (10): 798-802.
26. Furler J, Spitzer O, Young D, Best J,. Insulin in general practice: barriers and enablers for timely initiation. Aust Fam Physician 2011; 40 (8): 617-21.
27. Goderis G, Borgermans L, Mathieu C, et al., Barriers and facilitators to evidence based care of type 2 diabetes patients: experiences of general practitioners participating to a quality improvement program. Implement Sci 2009; 4: 41.
28. Brown JB, Harris SB, Webster-Bogaert S, Wetmore S, Faulds C, Stewart M,. The role of patient, physician and systemic factors in the management of type 2 diabetes mellitus. Fam Pract 2002; 19 (4): 344-9.
29. Nakar S, Yitzhaki G, Rosenberg R, Vinker S,. Transition to insulin in type 2 diabetes: family physicians' misconception of patients' fears contributes to existing barriers. J Diabetes Complications 2007; 21: 220-6.
30. Yoshioka N, Ishii H, Tajima N, Iwamoto Y,. Differences in physician and patient perceptions about insulin therapy for management of type 2 diabetes: the DAWN Japan study. Curr Med Res Opin 2014; 30 (2): 177-83.
31. Bogatean MP, Hancu N,. People with type 2 diabetes facing the reality of starting insulin therapy: factors involved in psychological insulin resistance. Pract Diabetes Int 2004; 21 (7): 247-52.
32. Grant RW, Wexler DJ, Watson AJ, et al., How doctors choose medications to treat type 2 diabetes: a national survey of specialists and academic generalists. Diabetes Care 2007; 30 (6): 1448-53.
33. Lakkis NA, Maalouf GJ, Mahmassani DM, Hamadeh GN,. Insulin therapy attitudes and beliefs of physicians in Middle Eastern Arab countries. Fam Pract 2013; 30 (5): 560-7.
34. Hunt LM, Valenzuela MA, Pugh JA,. NIDDM patients' fears and hopes about insulin therapy. The basis of patient reluctance. Diabetes Care 1997; 20 (3): 292-8.
35. Oliveria SA, Menditto LA, Ulcickas Yood M, Koo YH, Wells KE, McCarthy BD,. Barriers to the initiation of, and persistence with, insulin therapy. Curr Med Res Opin 2007; 23 (12): 3105-12.
36. Brunton S,. Insulin delivery systems: reducing barriers to insulin therapy and advancing diabetes mellitus treatment. Am J Med 2008; 121 (6 Suppl.): S35-41.
37. Rosenstock J, Davies M, Home PD, Larsen J, Koenen C, Schernthaner G,. A randomised, 52-week, treat-to-target trial comparing insulin detemir with insulin glargine when administered as add-on to glucose-lowering drugs in insulin-naive people with type 2 diabetes. Diabetologia 2008; 51 (3): 408-16.
38. Garber AJ,. Long-acting glucagon-like peptide 1 receptor agonists: a review of their efficacy and tolerability. Diabetes Care 2011; 34 (Suppl. 2): S279-S284.
39. Lee YK, Lee PY, Ng CJ,. Tactics in counselling patients to start insulin. Diabetic Med 2013; 30 (3): 373-4.
40. Mathers N, Ng CJ, Campbell MJ, Colwell B, Brown I, Bradley A,. Clinical effectiveness of a patient decision aid to improve decision quality and glycaemic control in people with diabetes making treatment choices: a cluster randomised controlled trial (PANDAs) in general practice. BMJ Open 2012; 2: e001469.