Efficacy of the natural clay, calcium aluminosilicate anti-diarrheal, in reducing medullary thyroid cancer-related diarrhea and its effects on quality of life: A pilot study

Thyroid

Volumn 25, Issue 10, 2015, Pages 1085-1090

  Dadu, Ramona ^a   Hu, Mimi I ^a   Cleeland, Charles ^a   Busaidy, Naifa L ^a   Habra, Mouhammed ^a   Waguespack, Steven G ^a   Sherman, Steven I ^a   Ying, Anita ^a   Fox, Patricia ^a   Cabanillas, Maria E ^a  

^a UNIVERSITY OF TEXAS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALUMINOSILICATE CALCIUM; ANTIDIARRHEAL AGENT; ATROPINE; CALCITONIN; COLESTIPOL; COLESTYRAMINE; DIPHENOXYLATE; LEVOTHYROXINE; LOPERAMIDE; OPIATE; ALUMINUM SILICATE;

ADULT; AGED; ARTICLE; BLOATING; CALCITONIN BLOOD LEVEL; CLAY; CLINICAL ARTICLE; CONSTIPATION; DIARRHEA; DISEASE SEVERITY; DISTANT METASTASIS; DRUG ABSORPTION; DRUG EFFICACY; DRUG SAFETY; DRUG TOLERABILITY; FECES ANALYSIS; FEMALE; FLATULENCE; HEARTBURN; HUMAN; MALE; MD ANDERSON SYMPTOM INVENTORY THYROID QUESTIONNAIRE; PILOT STUDY; PRIORITY JOURNAL; PROSPECTIVE STUDY; QUALITY OF LIFE; QUALITY OF LIFE ASSESSMENT; QUESTIONNAIRE; THYROID MEDULLARY CARCINOMA; TREATMENT DURATION; COMPLICATION; MEDULLARY CARCINOMA; MIDDLE AGED; THYROID TUMOR; TREATMENT OUTCOME;

ADULT; AGED; ALUMINUM SILICATES; ANTIDIARRHEALS; CARCINOMA, MEDULLARY; DIARRHEA; FEMALE; HUMANS; MALE; MIDDLE AGED; PILOT PROJECTS; PROSPECTIVE STUDIES; QUALITY OF LIFE; THYROID NEOPLASMS; TREATMENT OUTCOME;

EID: 84942793443     PISSN: 10507256     EISSN: 15579077     Source Type: Journal    
DOI: 10.1089/thy.2015.0166     Document Type: Article

References (25)

1. Wells SA Jr, Robinson BG, Gagel RF, Dralle H, Fagin JA, Santoro M, Baudin E, Elisei R, Jarzab B, Vasselli JR, Read J, Langmuir P, Ryan AJ, Schlumberger MJ 2012 Vandetanib in patients with locally advanced or metastatic medullary thyroid cancer: a randomized, double-blind phase III trial. J Clin Oncol 30: 134-141
2. Elisei R, Schlumberger MJ, Muller SP, Schoffski P, Brose MS, Shah MH, Licitra L, Jarzab B, Medvedev V, Kreissl MC, Niederle B, Cohen EE, Wirth LJ, Ali H, Hessel C, Yaron Y, Ball D, Nelkin B, Sherman SI 2013 Cabozantinib in progressive medullary thyroid cancer. J Clin Oncol 31: 3639-3646
3. Cabanillas ME, Hu MI, Jimenez C 2014 Medullary thyroid cancer in the era of tyrosine kinase inhibitors: to treat or not to treat-and with which drug-those are the questions. J Clin Endocrinol Metab 99: 4390-4396
4. Kiesewetter B, Raderer M 2013 Ondansetron for diarrhea associated with neuroendocrine tumors. N Engl J Med 368: 1947-1948
5. Rubin J, Ajani J, Schirmer W, Venook AP, Bukowski R, Pommier R, Saltz L, Dandona P, Anthony L 1999 Octreotide acetate long-acting formulation versus open-label subcutaneous octreotide acetate in malignant carcinoid syndrome. J Clin Oncol 17: 600-606
6. Modlin IM, Pavel M, Kidd M, Gustafsson BI 2010 Review article: somatostatin analogues in the treatment of gastroenteropancreatic neuroendocrine (carcinoid) tumours. Aliment Pharmacol Ther 31: 169-188
7. Fawell WN, Thompson G 1973 Nutmeg for diarrhea of medullary carcinoma of thyroid. N Engl J Med 289: 108-109
8. Williams ED, Karim SM, Sandler M 1968 Prostaglandin secretion by medullary carcinoma of the thyroid. A possible cause of the associated idarrhoea. Lancet 1: 22-23
9. Rambaud JC, Jian R, Flourie B, Hautefeuille M, Salmeron M, Thuillier F, Ruskone A, Florent C, Chaoui F, Bernier JJ 1988 Pathophysiological study of diarrhoea in a patient with medullary thyroid carcinoma. Evidence against a secretory mechanism and for the role of shortened colonic transit time. Gut 29: 537-543
10. Cox TM, Fagan EA, Hillyard CJ, Allison DJ, Chadwick VS 1979 Role of calcitonin in diarrhoea associated with medullary carcinoma of the thyroid. Gut 20: 629-633
11. Jensen RT 1999 Overview of chronic diarrhea caused by functional neuroendocrine neoplasms. Semin Gastrointest Dis 10: 156-172
12. Gonzalez R, De Medina FS, Martinez-Augustin O, Nieto A, Galvez J, Risco S, Zarzuelo A 2004 Anti-inflammatory effect of diosmectite in hapten-induced colitis in the rat. Br J Pharmacol 141: 951-960
13. More J, Benazet F, Fioramonti J, Droy-Lefaix MT 1987 Effects of treatment with smectite on gastric and intestinal glycoproteins in the rat: a histochemical study. Histochem J 19: 665-670
14. Afriyie-Gyawu E, Mackie J, Dash B, Wiles M, Taylor J, Huebner H, Tang L, Guan H, Wang JS, Phillips T 2005 Chronic toxicological evaluation of dietary NovaSil clay in Sprague-Dawley rats. Food Addit Contam 22: 259-269
15. Phillips TD 1999 Dietary clay in the chemoprevention of aflatoxin-induced disease. Toxicol Sci 52: 118-126
16. Hahn KA, Carpenter RH 2008 Calcium aluminosilicate (CAS) in the treatment of intractable diarrhea in dogs with cancer. Intern J Appl Res Vet Med 6: 181-184
17. Kee BK, Morris JS, Slack RS, Crocenzi T, Wong L, Esparaz B, OvermanM, Glover K, Jones D, Wen S, Fisch MJ 2015 A phase II, randomized, double blind trial of calcium aluminosilicate clay versus placebo for the prevention of diarrhea in patients with metastatic colorectal cancer treated with irinotecan. Support Care Cancer 23: 661-670
18. Cleeland CS, Mendoza TR, Wang XS, Chou C, Harle MT, Morrissey M, Engstrom MC 2000 Assessing symptom distress in cancer patients: the MD Anderson Symptom Inventory. Cancer 89: 1634-1646
19. Gning I, Trask PC, Mendoza TR, Harle MT, Gutierrez KA, Kitaka SA, Sherman SI, Cleeland CS 2009 Development and initial validation of the thyroid cancer module of the MD Anderson Symptom Inventory. Oncology 76: 59-68
20. Sherman SI, Tielens ET, Ladenson PW 1994 Sucralfate causes malabsorption of L-thyroxine. Am J Med 96: 531-535
21. Yen ZS, Lai MS 2006 Best evidence topic report. Smectite for acute diarrhoea in children. Emerg Med J 23: 65-66
22. Yao-Zong Y, Shi-Rong L, Delvaux M 2004 Comparative efficacy of dioctahedral smectite (Smecta) and a probiotic preparation in chronic functional diarrhoea. Dig Liver Dis 36: 824-828
23. Szajewska H, Dziechciarz P, Mrukowicz J 2006 Metaanalysis: Smectite in the treatment of acute infectious diarrhoea in children. Aliment Pharmacol Ther 23: 217-227
24. Madkour AA, Madina EM, el-Azzouni OE, Amer MA, el-Walili TM, Abbass T 1993 Smectite in acute diarrhea in children: a double-blind placebo-controlled clinical trial. J Pediatr Gastroenterol Nutr 17: 176-181
25. Mahraoui L, HeymanM, Plique O, Droy-LefaixMT, Desjeux JF 1997 Apical effect of diosmectite on damage to the intestinal barrier induced by basal tumour necrosis factor-alpha. Gut 40: 339-343