PET/CT Systems

Emission Tomography: The Fundamentals of PET and SPECT

Volumn , Issue , 2004, Pages 195-212

  Watson, Charles C ^a   Townsend, David W ^b   Bendriem, Bernard ^a  

^a CPS Innovations   (United States)

^b UNIVERSITY OF TENNESSEE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 84942767386     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1016/B978-012744482-6.50014-4     Document Type: Chapter

References (71)

1. Antoch G., Freudenberg L.S., Debatin J.F., Mueller S.P., Beyer T., Bockisch A., Stattaus J. A radiologist's perspective on dual-modality PET/CT: Optimized CT scanning protocols and their effect on PET quality. J. Nucl. Med. 2002, 43. 307P.
2. Bailey D.L., Young H., Bloomfield P.M., Meikle S.R., Glass D., Meyers M.J., Spinks T.J., Watson C.C., Luk P., Peters A.M., Jones T. ECAT ART-a continuously rotating PET camera: Performance characteristics, initial clinical studies, and installation considerations in a nuclear medicine department. Eur. J. Nucl. Med. 1997, 24:6-15.
3. Bar-Shalom R., Keidar Z., Guralnik L., Yefremov N., Sachs J., Israel O. Added value of fused PET/CT imaging with FDG in diagnostic imaging and management of cancer patients. J. Nucl. Med. 2002, 43. 32P.
4. Beyer T., Townsend D.W., Brun T., Kinahan P.E., Charron M., Roddy R., Jerin J., Young J., Byars L., Nutt R. A combined PET/CT scanner for clinical oncology. J. Nucl. Med. 2000, 41(8):1369-1379.
5. Blankespoor S.C., Wu X., Kalki K., Brown J.K., Tang H.R., Cann C.E., Hasegawa B.H. Attenuation correction of SPECT using x-ray CT on an emission-transmission CT system: Myocardial perfusion assessment. IEEE Trans. Nucl. Sci. 1996, 43(4):2263-2274.
6. Blodgett T., Beyer T., Antoch G., Mueller S., Freudenberg L., Akhurst T. The effect of respiratory motion on PET/CT image quality. J. Nucl. Med. 2002, 43. 58P.
7. Bocher M., Balan A., Krausz Y., Shrem Y., Lonn A., Wilk M., Chisin R. Gamma-camera mounted anatomical x-ray tomography: Technology, system characteristics and first images. Eur. J. Nucl. Med. 2000, 27(6):619-627.
8. Burger C., Schoenes S., Goerres G., Buck A., Von Schulthess G.K. Transformation of CT-values into 511 keV attenuation coefficients for usage in PET attenuation correction. J. Nucl. Med. 2001, 42. 57P.
9. Carney J., Beyer T., Brasse D., Yap J.T., Townsend D.W. Clinical PET/CT scanning using oral CT contrast agents. J. Nucl. Med. 2002, 43. 57P.
10. Carney J., Townsend D.W., Kinahan P.E., Beyer T., Kachelriess M., Kalender W.A., De Man B., Nuyts J. CT-based attenuation correction: The effects of imaging with the arms in the field of view. J. Nucl. Med. 2001, 42. 56P.
11. Centers for Medicare & Medicaid Services Positron emission tomography (PET) scans. National Coverage Determination, no. 6, October 1, 2002 2002, Centers for Medicare & Medicaid Services, Dordrecht.
12. Charron M., Beyer T., Bohnen N.N., Kinahan P.E., Dachille M., Jerin J., Nutt R., Meltzer C.C., Villemagne V., Townsend D.W. Image analysis in patients with cancer studied with a combined PET and CT scanner. Clin. Nucl. Med. 2000, 25(11):905-910.
13. Chin B.B., Nakamoto Y., Kraitchman D.L., Clark P., Wahl R.L. Quantitative differences in 18FDG uptake due to respiratory motion in PET CT: Attenuation correction using CT in end inspiration and end expiration versus 68Ge correction. J. Nucl. Med. 2002, 43. 58P.
14. Cohade C., Osman M., Marshall L., Wahl R.L. Metallic object artifacts on PET-CT: Clinical and phantom studies. J. Nucl. Med. 2002, 43. 308P.
15. Comtat C., Kinahan P.E., Fessler J.A., Beyer T., Townsend D.W., Defrise M., Michel C. Clinically feasible reconstruction of 3D whole-body PET/CT data using blurred anatomical labels. Phys. Med. Biol. 2002, 47(1):1-20.
16. Dahlbom M., Hoffman E.J. Problems in signal-to-noise ratio for attenuation correction in high resolution PET. IEEE Trans. Nucl. Sci. 1987, 34:288-293.
17. Dahlbom M., Reed J., Young J. Implementation of true continuous bed motion in 2-D and 3-D whole-body PET scanning. IEEE Trans. Nucl. Sci. 2001, 48:1465-1469.
18. Delbeke D., Martin W.H., Patton J.A., Sandler M.P. Value of iterative reconstruction, attenuation correction, and image fusion in the interpretation of FDG PET images with an integrated dual-head coincidence camera and x-ray-based attenuation maps. Radiology 2001, 218:163-171.
19. Deloar H.M., Fujiwara T., Shidahara M., Nakamura T., Watabe H., Narita Y., Itoh M., Miyake M., Watanuki S. Estimation of absorbed dose for 2-[F-18]fluoro-2-deoxy-d-glucose using wholebody positron emission tomography and magnetic resonance imaging. Eur. J. Nucl. Med. 1998, 25:565-574.
20. Dizendorf E., Ciernik I.F., Baumert B., von Schulthess G.K., Luetolf U.M., Steinert H.C. Impact of integrated PETCT scanning on external beam radiation treatment planning. J. Nucl. Med. 2002, 43. 33P.
21. Dizendorf E.V., Treyer V., Von Schulthess G.K., Hany T.F. Application of oral contrast media in coregistered positron emission tomography-CT. Am. J. Roentgenol. 2002, 179:477-481.
22. Erdi Y.E., Macapinlac H., Rosenzweig K.E., Humm J.L., Larson S.M., Erdi A.K., Yorke E.D. Use of PET to monitor the response of lung cancer to radiation treatment. Eur. J. Nucl. Med. 2000, 27:861-866.
23. Erdi Y.E., Rosenzweig K., Erdi A.K., Macapinlac H.A., Hu Y.C., Braban L.E., Humm J.L., Squire O.D., Chui C.S., Larson S.M., Yorke E.D. Radiotherapy treatment planning for patients with non-small cell lung cancer using positron emission tomography (PET). Radiother. Oncol. 2002, 62:51-60.
24. Eriksson L., Watson C.C., Eriksson M., Casey M.E., Loope M., Schmand M., Bendriem B., Nutt R. On the effect of x-rays on the PET detectors in a PET/CT system. 2002 IEEE Nucl. Sci. Symp. Conf. Rec. 2002, paper M11-M40.
25. Eubank W.B., Mankoff D.A., Schmiedl U.P., Winter T.C., Fisher E.R., Olshen A.B., Graham M.M., Eary J.F. Imaging of oncologic patients: Benefit of combined CT and FDG PET in the diagnosis of malignancy. Am. J. Roentgenol. 1998, 171:1103-1110.
26. Freudenberg L.S., Antoch G., Mueller S.P., Stattaus J., Eberhardt W., Debatin J., Bockisch A. Preliminary results of whole body FDG-PET/CT in lymphoma. J. Nucl. Med. 2002, 43. 30P.
27. Freudenberg L.S., Mueller S., Antoch G., Beyer T., Knust J., Goerges R., Jentzen W.J., Brandau W., Debatin J., Bockisch A. Value of 124I PET/CT in staging of patients with differentiated thyroid cancer. J. Nucl. Med. 2002, 43. 280P.
28. Goerres G.W., Kamel E., Seifert B., Burger C., Buck A., Hany T.F., von Schulthess G.K. Accuracy of image coregistration of pulmonary lesions in patients with non-small cell lung cancer using an integrated PET/CT system. J. Nucl. Med. 2002, 43:1469-1475.
29. Hany T.F., Steinert H.C., Goerres G.W., Buck A., von Schulthess G.K. PET diagnostic accuracy: Improvement with in-line PET-CT system, initial results. Radiology 2002, 225:575-581.
30. Hasegawa B.H., Lang T.F., Brown J.K., Gingold E.L., Reilly S.M., Blankespoor S., Liew S.C., Tsui B.M.W., Ramanathan C. Object-specific attenuation correction of SPECT with correlated dual-energy x-ray CT. IEEE Trans. Nucl. Sci. 1993, 40(4):1242-1252.
31. Hays M.T., Watson E.E., Thomas S.R., Stabin M. MIRD dose estimate report no. 19: Radiation absorbed dose estimates from 18F-FDG. J. Nucl. Med. 2002, 43:210-214.
32. Hubbell J.H., Seltzer S.M. Tables of X-ray mass attenuation coefficients and mass energy-absorption coefficients (version 1.03) 1997, [Online]. Available: http://physics.nist.gov/xaamdi [2002, August 16], National Institute of Standards and Technology, Baltimore, MD.
33. International Commission on Radiation Units and Measurements Tissue Substitutes in Radiation Dosimetry and Measurement 1989, Report no. 44, Nuclear Technology Publishing, Gaithersburg, MD.
34. International Commission on Radiological Protection Radiation Dose to Patients from Radiopharmaceuticals 1998, Publication 80, Elsevier Science, Ashford, UK.
35. International Commission on Radiological Protection Managing Patient Dose in Computed Tomography 2001, Publication 87, Elsevier Science, Tarrytown, New York.
36. Israel O., Mor M., Gaitini D., Keidar Z., Guralnik L., Engel A., Frenkel A., Bar-Shalom R., Kuten A. Combined functional and structural evaluation of cancer patients with a hybrid camera-based PET/CT system using 18F-FDG. J. Nucl. Med. 2002, 43:1129-1136.
37. Jackson D.F., Hawkes D.J. X-ray attenuation coefficients of elements and mixtures. Phys. Rep. 1981, 70:169-233.
38. Jaroff L. A winning combination. Time 2000, 156(23):72-74.
39. Kalender W.A. Computed Tomography 2000, Publicis MCD Verlag, Tarrytown, New York.
40. Kalender W.A., Seissler W., Klotz E., Vock P. Spiral volumetric CT with singe-breath-hold technique, continuous transport, and continuous scanner rotation. Radiology 1990, 176:181-183.
41. Kalender W.A., Wolf H., Suess C., Gies M., Greess H., Bautz W.A. Dose reduction in CT by on-line tube current control: Principles and validation on phantoms and cadavers. Eur. Radiol. 1999, 2:323-328.
42. Keidar Z., Bar-Shalom R., Guralnik L., Yefremov N., Kagana O., Gaitini D., Israel O. Hybrid imaging using PET/CT with 18F-FDG in suspected recurrence of lung cancer: Diagnostic value and impact on patient management. J. Nucl. Med. 2002, 43. 32P.
43. Kiffer J.D., Berlangieri S.U., Scott A.M., Quong G., Feigen M., Schumer W., Clarke C.P., Knight S.R., Daniel F.J. The contribution of 18F-fluoro-2-deoxy-glucose positron emission tomographic imaging to radiotherapy planning in lung cancer. Lung Cancer 1998, 19:167-177.
44. Kinahan P.E., Townsend D.W., Beyer T., Sashin D. Attenuation correction for a combined 3D PET/CT scanner. Med. Phys. 1998, 25:2046-2053.
45. Kluetz P.G., Meltzer C.C., Villemagne V.L., Kinahan P.E., Chander S., Martinelli M.A., Townsend D.W. Combined PET/CT imaging in oncology: Impact on patient management. Clin. Positron Imag. 2000, 3:223-230.
46. Lang T.F., Hasegawa B.H., Liew S.C., Brown J.K., Blankespoor S., Reilly S.M., Gingold E.L., Cann C.E. A prototype emission-transmission imaging system. 1991 IEEE Nucl. Sci. Symp. Conf. Rec. 1991, 3:1902-1906.
47. Lang T.F., Hasegawa B.H., Liew S.C., Brown J.K., Blankespoor S., Reilly S.M., Gingold E.L., Cann C.E. Description of a prototype emission-transmission computed tomography imaging system. J. Nucl. Med. 1992, 33:1881-1887.
48. Matthies A., Hickeson M., Cuchiara A., Alavi A. Dual time point 18F-FDG PET for the evaluation of pulmonary nodules. J. Nucl. Med. 2002, 43:871-875.
49. Mehta L., Echt E.A., Nelson A.D., Devlin A.L. Limitations of CT/PET fusion using software based algorithms. J. Nucl. Med. 2002, 43. 305P.
50. Meltzer C.C., Martinelli M.A., Beyer T., Kinahan P.E., Charron M., McCook B., Townsend D.W. Whole-body FDG PET imaging in the abdomen: value of combined PET/CT. J. Nucl. Med. 2001, 42. 35P.
51. Meltzer C.C., Snyderman C.H., Fukui M.B., Bascom D.A., Chander S., Johnson J.T., Myers E.N., Martinelli M.A., Kinahan P.E., Townsend D.W. Combined FDG PET/CT imaging in head and neck cancer: Impact on patient management. J. Nucl. Med. 2001, 42. 36P.
52. McCullough E.C. Photon attenuation in computed tomography. Med. Phys. 1975, 2:307-320.
53. Nahmias C., Nutt R., Hichwa R.D., Czernin J., Melcher C., Schmand M., Andreaco M., Eriksson L., Casey M., Moyers C., Michel C., Bruckbauer T., Conti M., Bendriem B., Hamill J. PET tomograph designed for five minute routine whole body studies. J. Nucl. Med. 2002, 43. 11P.
54. Performance Measurements of Positron Emission Tomographs. NEMA Standards Publication NU 2-2001 2001, National Electrical Manufacturers Association, NEMA, Munich.
55. Nehmeh S.A., Erdi Y.E., Ling C.C., Rosenzweig K.E., Schoder H., Larson S.M., Macapinlac H.A., Squire O.D., Humm J.L. Effect of respiratory gating on quantifying PET images of lung cancer. J. Nucl. Med. 2002, 43:876-881.
56. Osman M.M., Cohade C., Leal J., Wahl R.L. Direct comparison of FDG-PET and PET-CT imaging in staging and re-staging patients with lung cancer. J. Nucl. Med. 2002, 43. 151P.
57. Patton J.A., Delbeke D., Sandler M.P. Image fusion using an integrated, dual-head coincidence camera with X-ray tube-based attenuation maps. J. Nucl. Med. 2000, 41:1364-1368.
58. Pietrzyk U., Herholz K., Heiss W.D. Three-dimensional alignment of functional and morphological tomograms. J. Comput. Assist. Tomogr. 1990, 14:51-59.
59. Rutherford R.A., Pullman B.R., Isherwood I. Measurement of effective atomic number and electron density using an EMI scanner. Neuroradiology 1976, 11:15-21.
60. Saleem A., Yap J., Osman S., Brady F., Suttle B., Lucas S.V., Jones T., Price P.M., Aboagye E.O. Modulation of fluorouracil tissue pharmacokinetics by eniluracil: In-vivo imaging of drug action. Lancet 2000, 355:2125-2131.
61. Stearns C.W. PET/CT scanner design. Paper presented at the SNM Mid-winter Educational Symposium 2002.
62. Steinert H.C., Hany T.F., Kamel E., Lardinois D., Weder W., von Schulthess G.K. Impact of integrated PETCT scanning on pre-operative staging of lung cancer. J. Nucl. Med. 2002, 43. 151P.
63. Tai Y.-C., Lin K.P., Hoh C.K., Huang S.C.H., Hoffman E.J. Utilization of 3-D elastic transformation in the registration of chest x-ray CT and whole body PET. IEEE Trans. Nucl. Sci. 1997, 44:1606-1612.
64. Toth T.L., Bromberg N.B., Pan T.S., Rabe J., Woloschek S.J., Li J., Seidenschnur G.E. A dose reduction x-ray beam positioning system for high-speed multislice CT scanners. Med. Phys. 2000, 27:2659-2668.
65. Townsend D.W., Beyer T., Kinahan P.E., Brun T., Roddy R., Nutt R., Byars L.G. The SMART scanner: A combined PET/CT tomograph for clinical oncology. 1998 IEEE Nucl. Sci. Symp. Conf. Rec. 1998, paper M5-M1.
66. Townsend D.W., Cherry S.R. Combining anatomy with function: The path to true image fusion. Eur. Radiol. 2001, 11:1968-1974.
67. Townsend D.W., Newport D.F., Brasse D., Carney J.P., Yap J.T., Reynolds C., Reed J., Bao J., Luk P., Beyer T. Wholebody combined PET/CT scanning with continuous bed movement. J. Nucl. Med. 2002, 43. 11P.
68. Wahl R.L., Quint L.E., Cieslak R.D., Aisen A.M., Koeppe R.A., Meyer C.R. "Anatometabolic" tumor imaging: Fusion of FDG PET with CT or MRI to localize foci of increased activity. J. Nucl. Med. 1993, 34:1190-1197.
69. Watanabe Y. Derivation of linear attenuation coefficients from CT numbers for low-energy photons. Phys. Med. Biol. 1999, 44:2201-2211.
70. Woods R.P., Mazziotta J.C., Cherry S.R. MRI-PET registration with an automated algorithm. J. Comput. Assist. Tomogr. 1993, 17:536-546.
71. Yeung H.W., Schoder H., Larson S.M. Utility of PET/CT for assessing equivocal PET lesions in oncology-initial experience. J. Nucl. Med. 2002, 43. 32P.