Directed evolution of artificial enzymes (XNAzymes) from diverse repertoires of synthetic genetic polymers

Nature Protocols

Volumn 10, Issue 10, 2015, Pages 1625-1642

  Taylor, Alexander I ^a   Holliger, Philipp ^a  

^a MRC LABORATORY OF MOLECULAR BIOLOGY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; DNA POLYMERASE; ENDONUCLEASE; LIGASE; OLIGONUCLEOTIDE; POLYMER; SYNTHETIC GENETIC POLYMER; UNCLASSIFIED DRUG; ENZYME;

ARTICLE; CATALYST; DNA ISOLATION; DNA TEMPLATE; ENZYME ENGINEERING; ENZYME ISOLATION; ENZYME SUBSTRATE; GENE AMPLIFICATION; HYDROLYSIS; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; REVERSE TRANSCRIPTION; RNA CLEAVAGE; SEQUENCE ANALYSIS; CHEMISTRY; DIRECTED MOLECULAR EVOLUTION; GENETICS; METABOLISM; MOLECULAR GENETICS; NUCLEIC ACID AMPLIFICATION; NUCLEOTIDE SEQUENCE; SYNTHESIS; SYSTEMATIC EVOLUTION OF LIGANDS BY EXPONENTIAL ENRICHMENT APTAMER TECHNIQUE;

BASE SEQUENCE; DIRECTED MOLECULAR EVOLUTION; ENZYMES; MOLECULAR SEQUENCE DATA; NUCLEIC ACID AMPLIFICATION TECHNIQUES; POLYMERS; SELEX APTAMER TECHNIQUE;

EID: 84942520548     PISSN: 17542189     EISSN: 17502799     Source Type: Journal    
DOI: 10.1038/nprot.2015.104     Document Type: Article

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