Antifungal de-escalation was not associated with adverse outcome in critically ill patients treated for invasive candidiasis: post hoc analyses of the AmarCAND2 study data

Intensive Care Medicine

Volumn 41, Issue 11, 2015, Pages 1931-1940

  Bailly, Sébastien ^a,b   Leroy, Olivier ^c   Montravers, Philippe ^d   Constantin, Jean Michel ^e   Dupont, Hervé ^f   Guillemot, Didier ^g   Lortholary, Olivier ^h,i   Mira, Jean Paul ^j,k   Perrigault, Pierre François ^l   Gangneux, Jean Pierre ^m   Azoulay, Elie ⁿ   Timsit, Jean François ^a,d  

^a UNIVERSITÉ PARIS DIDEROT   (France)

^b UNIV GRENOBLE ALPES   (France)

^c Chatiliez Hospital   (France)

^d BICHAT HOSPITAL   (France)

^e UNIVERSITY HOSPITAL OF CLERMONT FERRAND   (France)

^f AMIENS UNIVERSITY HOSPITAL   (France)

^g Pharmacoepidemiology and Infectious Diseases (B2PHI)   (France)

^h UNIVERSITÉ PARIS DESCARTES   (France)

ⁱ INSTITUT PASTEUR   (France)

^j Montpellier University Hospital ^*  (France)

^k University Sorbonne Paris Cite   (France)

^l MONTPELLIER UNIVERSITY HOSPITAL   (France)

^m RENNES UNIVERSITY HOSPITAL   (France)

ⁿ SAINT LOUIS HOSPITAL   (France)

more..

Author keywords

Antifungal; Causal inference; De escalation; Intensive care unit; Invasive candidiasis; Outcome; Sepsis

Indexed keywords

AMPHOTERICIN B; ANTIFUNGAL AGENT; ECHINOCANDIN; FLUCONAZOLE; VORICONAZOLE;

ADULT; ADVERSE OUTCOME; AGED; ARTICLE; CONTROLLED STUDY; CRITICALLY ILL PATIENT; DRUG DOSE ESCALATION; FEMALE; HUMAN; INTENSIVE CARE UNIT; INVASIVE CANDIDIASIS; MAJOR CLINICAL STUDY; MALE; MORTALITY; MULTICENTER STUDY; POST HOC ANALYSIS; PROGNOSIS; TREATMENT OUTCOME; CANDIDIASIS, INVASIVE; COMORBIDITY; CRITICAL ILLNESS; DISEASE COURSE; EPIDEMIOLOGY; FRANCE; HOSPITAL MORTALITY; MIDDLE AGED; MULTICENTER STUDY (TOPIC); OBSERVATION; PROSPECTIVE STUDY; SEVERITY OF ILLNESS INDEX; STATISTICAL MODEL; STATISTICS AND NUMERICAL DATA; SURVIVAL ANALYSIS; TIME TO TREATMENT;

AGED; ANTIFUNGAL AGENTS; CANDIDIASIS, INVASIVE; COMORBIDITY; CRITICAL ILLNESS; DISEASE PROGRESSION; ECHINOCANDINS; FEMALE; FLUCONAZOLE; FRANCE; HOSPITAL MORTALITY; HUMANS; INTENSIVE CARE UNITS; LOGISTIC MODELS; MALE; MIDDLE AGED; MULTICENTER STUDIES AS TOPIC; OBSERVATION; OUTCOME AND PROCESS ASSESSMENT (HEALTH CARE); PROSPECTIVE STUDIES; SEVERITY OF ILLNESS INDEX; SURVIVAL ANALYSIS; TIME-TO-TREATMENT;

EID: 84942504890     PISSN: 03424642     EISSN: 14321238     Source Type: Journal    
DOI: 10.1007/s00134-015-4053-1     Document Type: Article

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