Antimicrobial de-escalation in septic cancer patients: is it safe to back down?

Intensive Care Medicine

Volumn 41, Issue 11, 2015, Pages 2022-2023

  Paskovaty, Alla ^a   Pastores, Stephen M ^a   Gedrimaite, Zivile ^a   Kostelecky, Natalie ^a   Riedel, Elyn R ^a   Seo, Susan K ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; ANTIINFECTIVE AGENT;

ANTIBIOTIC RESISTANCE; ANTIBIOTIC THERAPY; CANCER CENTER; CANCER MORTALITY; CANCER PATIENT; HUMAN; INTENSIVE CARE UNIT; LENGTH OF STAY; LETTER; MIXED INFECTION; PATIENT SAFETY; PRACTICE GUIDELINE; RETROSPECTIVE STUDY; SEPSIS; SEQUENTIAL ORGAN FAILURE ASSESSMENT SCORE; TREATMENT DURATION; AGED; CAUSE OF DEATH; COMPLICATION; DRUG EFFECTS; ECONOMICS; EPIDEMIOLOGY; FEMALE; HOSPITAL MORTALITY; MALE; MIDDLE AGED; MORTALITY; NEOPLASMS; NEW YORK; STATISTICS AND NUMERICAL DATA;

AGED; ANTI-INFECTIVE AGENTS; CANCER CARE FACILITIES; CAUSE OF DEATH; DRUG RESISTANCE, MICROBIAL; FEMALE; HOSPITAL MORTALITY; HUMANS; INTENSIVE CARE UNITS; LENGTH OF STAY; MALE; MIDDLE AGED; NEOPLASMS; NEW YORK CITY; RETROSPECTIVE STUDIES; SEPSIS;

EID: 84942503933     PISSN: 03424642     EISSN: 14321238     Source Type: Journal    
DOI: 10.1007/s00134-015-4016-6     Document Type: Letter

References (3)

1. Weiss E, Zahar JR, Lesprit P, Ruppe E, Leone M, Chastre J, Lucet JC, Paugam-Burtz C, Brun-Buisson C, Timsit JF, De-escalation Study Group (2015) Elaboration of a consensual definition of de-escalation allowing a ranking of beta-lactams. Clin Microbiol Infect 21:649.e1–649.e10. doi:10.1016/j.cmi.2015.03.013
2. Mokart D, Slehofer G, Lambert J, Sannini A, Chow-Chine L, Brun JP, Berger P, Duran S, Faucher M, Blache JL, Saillard C, Vey N, Leone M (2014) De-escalation of antimicrobial treatment in neutropenic patients with severe sepsis: results from an observational study. Intensive Care Med 40:41–49
3. Joung MK, Lee JA, Moon SY, Cheong HS, Joo EJ, Ha YE, Sohn KM, Chung SM, Suh GY, Chung DR, Song JH, Peck KR (2011) Impact of de-escalation therapy on clinical outcomes for intensive care unit-acquired pneumonia. Crit Care 15:R79. doi:10.1186/cc10072