Protein arginine methyltransferase 10 is required for androgen-dependent proliferation of LNCaP prostate cancer cells

Bioscience, Biotechnology and Biochemistry

Volumn 79, Issue 9, 2015, Pages 1430-1437

  Harada, Naoki ^a   Takagi, Toshiki ^a   Nakano, Yoshihisa ^b   Yamaji, Ryoichi ^a   Inui, Hiroshi ^a  

^a Osaka Prefecture University   (Japan)

^b Osaka Women's Junior College   (Japan)

Author keywords

Androgen receptor; LNCaP cell; Prostate cancer; Protein arginine methyltransferase 10

Indexed keywords

AMINO ACIDS; ANTIGENS; ARGININE; CELL GROWTH; CELLS; CYTOLOGY; DISEASES; GROWTH KINETICS; PROTEINS; UROLOGY;

ANDROGEN RECEPTORS; HUMAN PROSTATE CANCER; LNCAP CELLS; PROSTATE CANCER CELLS; PROSTATE CANCERS; PROSTATE SPECIFIC ANTIGEN; PROTEIN-ARGININE METHYLTRANSFERASE; REPRODUCTIVE TISSUES;

CELL SIGNALING;

ANDROGEN RECEPTOR; MESSENGER RNA; PROTEIN ARGININE METHYLTRANSFERASE;

ANIMAL; BIOSYNTHESIS; CELL PROLIFERATION; GENE EXPRESSION REGULATION; GENETICS; HUMAN; MALE; METABOLISM; PATHOLOGY; PROSTATE; PROSTATE TUMOR; RAT; TUMOR CELL LINE;

ANIMALS; CELL LINE, TUMOR; CELL PROLIFERATION; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MALE; PROSTATE; PROSTATIC NEOPLASMS; PROTEIN-ARGININE N-METHYLTRANSFERASES; RATS; RECEPTORS, ANDROGEN; RNA, MESSENGER;

EID: 84942354228     PISSN: 09168451     EISSN: 13476947     Source Type: Journal    
DOI: 10.1080/09168451.2015.1025035     Document Type: Article

References (23)

1. Heinlein CA, Chang C. Androgen receptor in prostate cancer. Endocr. Rev. 2004;25:276-308.
2. Chang CS, Kokontis J, Liao ST. Molecular cloning of human and rat complementary DNA encoding androgen receptors. Science. 1988;240:324-326.
3. Shen HC, Coetzee GA. The androgen receptor: unlocking the secrets of its unique transactivation domain. Vitam. Horm. 2005;71:301-319.
4. Heinlein CA, Chang C. Androgen receptor (AR) coregulators: An overview. Endocr. Rev. 2002;23:175-200.
5. Jenster G, van der Korput HA, Trapman J, Brinkmann AO. Identification of two transcription activation units in the N-terminal domain of the human androgen receptor. J. Biol. Chem. 1995;270:7341-7346.
6. Siegel R, Naishadham D, Jemal A. Cancer statistics, 2012. CA Cancer J. Clin. 2012;62:10-29.
7. Prins GS, Birch L. The developmental pattern of androgen receptor expression in rat prostate lobes is altered after neonatal exposure to estrogen. Endocrinology. 1995;136:1303-1314.
8. Oesterling JE. Prostate specific antigen: A critical assessment of the most useful tumor marker for adenocarcinoma of the prostate. J. Urol. 1991;145:907-923.
9. Harada N, Yasunaga R, Higashimura Y, Yamaji R, Fujimoto K, Moss J, Inui H, Nakano Y. Glyceraldehyde-3-phosphate dehydrogenase enhances transcriptional activity of androgen receptor in prostate cancer cells. J. Biol. Chem. 2007;282: 22651-22661.
10. Harada N, Katsuki T, Takahashi Y, Masuda T, Yoshinaga M, Adachi T, Izawa T, Kuwamura M, Nakano Y, Yamaji R, Inui H. Androgen receptor silences thioredoxin-interacting protein and competitively inhibits glucocorticoid receptor-mediated apoptosis in pancreatic β-cells. J. Cell. Biochem. 2015. doi:10.1002/jcb.25054.
11. Harada N, Inoue K, Yamaji R, Nakano Y, Inui H. Androgen deprivation causes truncation of the C-terminal region of androgen receptor in human prostate cancer LNCaP cells. Cancer Sci. 2012;103:1022-1027.
12. Harada N, Yokoyama T, Yamaji R, Nakano Y, Inui H. RanBP10 acts as a novel coactivator for the androgen receptor. Biochem. Biophys. Res. Commun. 2008;368:121-125.
13. Wang L, Charoensuksai P, Watson NJ, Wang X, Zhao Z, Coriano CG, Kerr LR, Xu W. CARM1 automethylation is controlled at the level of alternative splicing. Nucleic Acids Res. 2013;41:6870-6880.
14. Jahan S, Davie JR. Protein arginine methyltransferases (PRMTs): role in chromatin organization. Adv. Biol. Regul. 2014;57: 173-184.
15. Krause CD, Yang ZH, Kim YS, Lee JH, Cook JR, Pestka S. Protein arginine methyltransferases: Evolution and assessment of their pharmacological and therapeutic potential. Pharmacol. Ther. 2007;113:50-87.
16. Bissinger EM, Heinke R, Spannhoff A, Eberlin A, Metzger E, Cura V, Hassenboehler P, Cavarelli J, Schule R, Bedford MT, Sippl W, Jung M. Acyl derivatives of p-aminosulfonamides and dapsone as new inhibitors of the arginine methyltransferase hPRMT1. Bioorg. Med. Chem. 2011;19:3717-3731.
17. Meyer R, Wolf SS, Obendorf M. PRMT2, a member of the protein arginine methyltransferase family, is a coactivator of the androgen receptor. J. Steroid Biochem. Mol. Biol. 2007;107:1-14.
18. Koh SS, Chen D, Lee YH, Stallcup MR. Synergistic enhancement of nuclear receptor function by p160 coactivators and two coactivators with protein methyltransferase activities. J. Biol. Chem. 2001;276:1089-1098.
19. Koh SS, Li H, Lee YH, Widelitz RB, Chuong CM, Stallcup MR. Synergistic coactivator function by coactivator-associated arginine methyltransferase (CARM) 1 and beta-catenin with two different classes of DNA-binding transcriptional activators. J. Biol. Chem. 2002;277:26031-26035.
20. Scaramuzzino C, Casci I, Parodi S, Lievens PM, Polanco MJ, Milioto C, Chivet M, Monaghan J, Mishra A, Badders N, Aggarwal T, Grunseich C, Sambataro F, Basso M, Fackelmayer FO, Taylor JP, Pandey UB, Pennuto M. Protein arginine methyltransferase 6 enhances polyglutamine-expanded androgen receptor function and toxicity in spinal and bulbar muscular atrophy. Neuron. 2015;85:88-100.
21. Jiang F, Wang Z. Identification of androgen-responsive genes in the rat ventral prostate by complementary deoxyribonucleic acid subtraction and microarray. Endocrinology. 2003;144: 1257-1265.
22. Halkidou K, Gnanapragasam VJ, Mehta PB, Logan IR, Brady ME, Cook S, Leung HY, Neal DE, Robson CN. Expression of Tip60, an androgen receptor coactivator, and its role in prostate cancer development. Oncogene. 2003;22:2466-2477.
23. Comuzzi B, Nemes C, Schmidt S, Jasarevic Z, Lodde M, Pycha A, Bartsch G, Offner F, Culig Z, Hobisch A. The androgen receptor co-activator CBP is up-regulated following androgen withdrawal and is highly expressed in advanced prostate cancer. J. Pathol. 2004;204:159-166.