Cell-Membrane-Mimicking Lipid-Coated Nanoparticles Confer Raman Enhancement to Membrane Proteins and Reveal Membrane-Attached Amyloid-β Conformation

ACS Nano

Volumn 9, Issue 9, 2015, Pages 9070-9077

  Bhowmik, Debanjan ^a   Mote, Kaustubh R ^b   MacLaughlin, Christina M ^c   Biswas, Nupur ^d   Chandra, Bappaditya ^a   Basu, Jaydeep K ^d   Walker, Gilbert C ^c   Madhu, Perunthiruthy K ^a,b   Maiti, Sudipta ^a  

^a TATA INSTITUTE OF FUNDAMENTAL RESEARCH   (India)

^b TATA INSTITUTE OF FUNDAMENTAL RESEARCH   (India)

^c UNIVERSITY OF TORONTO   (Canada)

^d INDIAN INSTITUTE OF SCIENCE   (India)

Author keywords

amyloid beta peptide; lipid SERS; lipid coated nanoparticles; membrane protein structures; oligomers; solid state NMR; surface enhanced Raman spectroscopy

Indexed keywords

BIOLOGICAL MEMBRANES; CELL MEMBRANES; CONFORMATIONS; CYTOLOGY; GLYCOPROTEINS; ISOTOPES; LIGHT POLARIZATION; LIGHT TRANSMISSION; LIPID BILAYERS; MEMBRANES; NANOPARTICLES; NEURODEGENERATIVE DISEASES; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; OLIGOMERS; RAMAN SPECTROSCOPY; SILVER;

AMYLOID-BETA PEPTIDES; COATED NANOPARTICLES; MEMBRANE PROTEIN STRUCTURES; SOLID STATE NMR; SURFACE ENHANCED RAMAN SPECTROSCOPY;

PROTEINS;

AMYLOID BETA PROTEIN; LIPID; LIPID BILAYER; MEMBRANE PROTEIN; NANOPARTICLE;

ALZHEIMER DISEASE; CELL MEMBRANE; CHEMISTRY; HUMAN; LIPID BILAYER; METABOLISM; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PATHOLOGY; PROTEIN CONFORMATION; PROTEIN MULTIMERIZATION; RAMAN SPECTROMETRY;

ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; CELL MEMBRANE; HUMANS; LIPID BILAYERS; LIPIDS; MAGNETIC RESONANCE SPECTROSCOPY; MEMBRANE PROTEINS; NANOPARTICLES; PROTEIN CONFORMATION; PROTEIN MULTIMERIZATION; SPECTRUM ANALYSIS, RAMAN;

EID: 84942346091     PISSN: 19360851     EISSN: 1936086X     Source Type: Journal    
DOI: 10.1021/acsnano.5b03175     Document Type: Article

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