Requisite analytic and diagnostic performance characteristics for the clinical detection of BRAF V600E in hairy cell leukemia: A comparison of 2 allele-specific PCR assays

Applied Immunohistochemistry and Molecular Morphology

Volumn 23, Issue 8, 2015, Pages 590-600

  Brown, Noah A ^a   Weigelin, Helmut C ^a   Bailey, Nathanael ^a   Laliberte, Julie ^b   Elenitoba Johnson, Kojo S J ^a   Lim, Megan S ^a   Betz, Bryan L ^a  

^a UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

^b Swift Bioscience   (United States)

Author keywords

allele specific PCR; analytic sensitivity; BRAF; hairy cell leukemia

Indexed keywords

CD5 ANTIGEN; FORMALDEHYDE; PARAFFIN; B RAF KINASE; BRAF PROTEIN, HUMAN; TUMOR MARKER;

ALLELE; ARTICLE; B CELL LYMPHOMA; BLOOD; BONE MARROW; BONE MARROW BIOPSY; BRAF V600E GENE; CANCER DIAGNOSIS; CLINICAL ARTICLE; CONTROLLED STUDY; GENE; GENE MUTATION; HAIRY CELL LEUKEMIA; HUMAN; HUMAN CELL; HUMAN TISSUE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; COMPARATIVE STUDY; GENETICS; IMMUNOLOGY; IMMUNOPHENOTYPING; LEUKEMIA, HAIRY CELL; MULTIPLEX POLYMERASE CHAIN REACTION; PROCEDURES; SENSITIVITY AND SPECIFICITY;

ALLELES; BIOMARKERS, TUMOR; HUMANS; IMMUNOPHENOTYPING; LEUKEMIA, HAIRY CELL; MULTIPLEX POLYMERASE CHAIN REACTION; PROTO-ONCOGENE PROTEINS B-RAF; SENSITIVITY AND SPECIFICITY;

EID: 84942292253     PISSN: 15412016     EISSN: 15334058     Source Type: Journal    
DOI: 10.1097/PAI.0000000000000024     Document Type: Article

References (20)

1. Tiacci E, Trifonov V, Schiavoni G, et al. BRAF mutations in hairycell leukemia. N Engl J Med. 2011;364:2305-2315.
2. Tiacci E, Schiavoni G, Forconi F, et al. Simple genetic diagnosis of hairy cell leukemia by sensitive detection of the BRAF-V600E mutation. Blood. 2012;119:192-195.
3. Blombery PA, Wong SQ, Hewitt CA, et al. Detection of BRAF mutations in patients with hairy cell leukemia and related lymphoproliferative disorders. Haematologica. 2012;97:780-783.
4. Arcaini L, Zibellini S, Boveri E, et al. The BRAF V600E mutation in hairy cell leukemia and other mature B-cell neoplasms. Blood. 2012;119:188-191.
5. Laurini JA, Aoun P, Iqbal J, et al. Investigation of the BRAF V600E mutation by pyrosequencing in lymphoproliferative disorders. Am J Clin Pathol. 2012;138:877-883.
6. Verma S, Greaves WO, Ravandi F, et al. Rapid detection and quantitation of BRAF mutations in hairy cell leukemia using a sensitive pyrosequencing assay. Am J Clin Pathol. 2012;138:153-156.
7. Langabeer SE, OBrien D, Liptrot S, et al. Correlation of the BRAF V600E mutation in hairy cell leukaemia with morphology, cytochemistry and immunophenotype. Int J Lab Hematol. 2012; 34:417-421.
8. Schnittger S, Bacher U, Haferlach T, et al. Development and validation of a real-time quantification assay to detect and monitor BRAFV600E mutations in hairy cell leukemia. Blood. 2012;119: 3151-3154.
9. Lennerz JK, Klaus BM, Marienfeld RB, et al. Pyrosequencing of BRAF V600E in routine samples of hairy cell leukaemia identifies CD5+ variant hairy cell leukaemia that lacks V600E. Br J Haematol. 2012;157:267-269.
10. Xi L, Arons E, Navarro W, et al. Both variant and IGHV4-34- expressing hairy cell leukemia lack the BRAF V600E mutation. Blood. 2012;119:3330-3332.
11. Swerdlow SH, Campo E, Harris NL, et al. WHO Classification of Tumours of Hematopoietic and Lymphoid Tissues. Lyon, France: IARC Press; 2008.
12. Hookim K, Roh MH, Willman J, et al. Application of immunocytochemistry and BRAF mutational analysis to direct smears of metastatic melanoma. Cancer Cytopathol. 2012;120:52-61.
13. Tsiatis AC, Norris-Kirby A, Rich RG, et al. Comparison of Sanger sequencing, pyrosequencing, and melting curve analysis for the detection of KRAS mutations: diagnostic and clinical implications. J Mol Diagn. 2010;12:425-432.
14. Furtado LV, Weigelin HC, Elenitoba-Johnson KS, et al. A multiplexed fragment analysis-based assay for detection of JAK2 exon 12 mutations. J Mol Diagn. 2013;15:592-599.
15. Cornfield DB, Mitchell Nelson DM, Rimsza LM, et al. The diagnosis of hairy cell leukemia can be established by flow cytometric analysis of peripheral blood, even in patients with low levels of circulating malignant cells. Am J Hematol. 2001;67: 223-226.
16. Grever MR. How I treat hairy cell leukemia. Blood. 2010;115:21-28.
17. Follows GA, Sims H, Bloxham DM, et al. Rapid response of biallelic BRAF V600E mutated hairy cell leukaemia to low dose vemurafenib. Br J Haematol. 2013;161:150-153.
18. Subbiah V, Subbiah IM. Killing two birds with one stone: BRAF V600E inhibitor therapy for hairy cell leukemia and Langerhans/ dendritic cell sarcoma. Ann Hematol. 2013;92:1149.
19. Dietrich S, Hullein J, Hundemer M, et al. Continued response off treatment after BRAF inhibition in refractory hairy cell leukemia. J Clin Oncol. 2013;31:e300-e303.
20. Munoz J, Schlette E, Kurzrock R. Rapid response to vemurafenib in a heavily pretreated patient with hairy cell leukemia and a BRAF mutation. J Clin Oncol. 2013;31:e351-e352.