-
2
-
-
84861198824
-
Biologic therapies in the metastatic colorectal cancer treatment continuum: applying current evidence to clinical practice
-
Peeters M., Price T. Biologic therapies in the metastatic colorectal cancer treatment continuum: applying current evidence to clinical practice. Cancer Treat Rev 2012, 38:397-406.
-
(2012)
Cancer Treat Rev
, vol.38
, pp. 397-406
-
-
Peeters, M.1
Price, T.2
-
3
-
-
42649145667
-
Wild-type KRAS is required for panitumumab efficacy in patients with metastatic colorectal cancer
-
Amado R.G., Wolf M., Peeters M., et al. Wild-type KRAS is required for panitumumab efficacy in patients with metastatic colorectal cancer. J Clin Oncol 2008, 26:1626-1634.
-
(2008)
J Clin Oncol
, vol.26
, pp. 1626-1634
-
-
Amado, R.G.1
Wolf, M.2
Peeters, M.3
-
4
-
-
78149250536
-
Randomized, phase III trial of panitumumab with infusional fluorouracil, leucovorin, and oxaliplatin (FOLFOX4) versus FOLFOX4 alone as first-line treatment in patients with previously untreated metastatic colorectal cancer: the PRIME study
-
Douillard J.Y., Siena S., Cassidy J., et al. Randomized, phase III trial of panitumumab with infusional fluorouracil, leucovorin, and oxaliplatin (FOLFOX4) versus FOLFOX4 alone as first-line treatment in patients with previously untreated metastatic colorectal cancer: the PRIME study. J Clin Oncol 2010, 28:4697-4705.
-
(2010)
J Clin Oncol
, vol.28
, pp. 4697-4705
-
-
Douillard, J.Y.1
Siena, S.2
Cassidy, J.3
-
5
-
-
84862026304
-
Addition of cetuximab to chemotherapy as first-line treatment for KRAS wild-type metastatic colorectal cancer: pooled analysis of the CRYSTAL and OPUS randomised clinical trials
-
Bokemeyer C., Van Cutsem E., Rougier P., et al. Addition of cetuximab to chemotherapy as first-line treatment for KRAS wild-type metastatic colorectal cancer: pooled analysis of the CRYSTAL and OPUS randomised clinical trials. Eur J Cancer 2012, 48:1466-1475.
-
(2012)
Eur J Cancer
, vol.48
, pp. 1466-1475
-
-
Bokemeyer, C.1
Van Cutsem, E.2
Rougier, P.3
-
6
-
-
84857993465
-
Clinical impact of anti-epidermal growth factor receptor monoclonal antibodies in first-line treatment of metastatic colorectal cancer: meta-analytical estimation and implications for therapeutic strategies
-
Loupakis F., Cremolini C., Salvatore L., et al. Clinical impact of anti-epidermal growth factor receptor monoclonal antibodies in first-line treatment of metastatic colorectal cancer: meta-analytical estimation and implications for therapeutic strategies. Cancer 2012, 118:1523-1532.
-
(2012)
Cancer
, vol.118
, pp. 1523-1532
-
-
Loupakis, F.1
Cremolini, C.2
Salvatore, L.3
-
7
-
-
21244450758
-
Association of k-ras, b-raf, and p53 status with the treatment effect of bevacizumab
-
Ince W.L., Jubb A.M., Holden S.N., et al. Association of k-ras, b-raf, and p53 status with the treatment effect of bevacizumab. J Natl Cancer Inst 2005, 97:981-989.
-
(2005)
J Natl Cancer Inst
, vol.97
, pp. 981-989
-
-
Ince, W.L.1
Jubb, A.M.2
Holden, S.N.3
-
9
-
-
57449095367
-
Wild-type BRAF is required for response to panitumumab or cetuximab in metastatic colorectal cancer
-
Di Nicolantonio F., Martini M., Molinari F., et al. Wild-type BRAF is required for response to panitumumab or cetuximab in metastatic colorectal cancer. J Clin Oncol 2008, 26:5705-5712.
-
(2008)
J Clin Oncol
, vol.26
, pp. 5705-5712
-
-
Di Nicolantonio, F.1
Martini, M.2
Molinari, F.3
-
10
-
-
59049089201
-
PI3KCA/PTEN deregulation contributes to impaired responses to cetuximab in metastatic colorectal cancer patients
-
Perrone F., Lampis A., Orsenigo M., et al. PI3KCA/PTEN deregulation contributes to impaired responses to cetuximab in metastatic colorectal cancer patients. Ann Oncol 2009, 20:84-90.
-
(2009)
Ann Oncol
, vol.20
, pp. 84-90
-
-
Perrone, F.1
Lampis, A.2
Orsenigo, M.3
-
11
-
-
77955277111
-
Effects of KRAS, BRAF, NRAS, and PIK3CA mutations on the efficacy of cetuximab plus chemotherapy in chemotherapy-refractory metastatic colorectal cancer: a retrospective consortium analysis
-
De Roock W., Claes B., Bernasconi D., et al. Effects of KRAS, BRAF, NRAS, and PIK3CA mutations on the efficacy of cetuximab plus chemotherapy in chemotherapy-refractory metastatic colorectal cancer: a retrospective consortium analysis. Lancet Oncol 2010, 11:753-762.
-
(2010)
Lancet Oncol
, vol.11
, pp. 753-762
-
-
De Roock, W.1
Claes, B.2
Bernasconi, D.3
-
12
-
-
84883680951
-
Panitumumab-FOLFOX4 treatment and RAS mutations in colorectal cancer
-
Douillard J.Y., Oliner K.S., Siena S., et al. Panitumumab-FOLFOX4 treatment and RAS mutations in colorectal cancer. N Engl J Med 2013, 369:1023-1034.
-
(2013)
N Engl J Med
, vol.369
, pp. 1023-1034
-
-
Douillard, J.Y.1
Oliner, K.S.2
Siena, S.3
-
13
-
-
84905870196
-
PEAK: a randomized, multicenter phase II study of panitumumab plus modified fluorouracil, leucovorin, and oxaliplatin (mFOLFOX6) or bevacizumab plus mFOLFOX6 in patients with previously untreated, unresectable, wild-type KRAS exon 2 metastatic colorectal cancer
-
Schwartzberg L.S., Rivera F., Karthaus M., et al. PEAK: a randomized, multicenter phase II study of panitumumab plus modified fluorouracil, leucovorin, and oxaliplatin (mFOLFOX6) or bevacizumab plus mFOLFOX6 in patients with previously untreated, unresectable, wild-type KRAS exon 2 metastatic colorectal cancer. J Clin Oncol 2014, 32:2240-2247.
-
(2014)
J Clin Oncol
, vol.32
, pp. 2240-2247
-
-
Schwartzberg, L.S.1
Rivera, F.2
Karthaus, M.3
-
14
-
-
84908573757
-
FOLFIRI plus cetuximab versus FOLFIRI plus bevacizumab as first-line treatment for patients with metastatic colorectal cancer (FIRE-3): a randomised, open-label, phase 3 trial
-
Heinemann V., von Weikersthal L.F., Decker T., et al. FOLFIRI plus cetuximab versus FOLFIRI plus bevacizumab as first-line treatment for patients with metastatic colorectal cancer (FIRE-3): a randomised, open-label, phase 3 trial. Lancet Oncol 2014, 15:1065-1075.
-
(2014)
Lancet Oncol
, vol.15
, pp. 1065-1075
-
-
Heinemann, V.1
von Weikersthal, L.F.2
Decker, T.3
-
15
-
-
84879786289
-
Panitumumab and irinotecan versus irinotecan alone for patients with KRAS wild-type, fluorouracil-resistant advanced colorectal cancer (PICCOLO): a prospectively stratified randomised trial
-
Seymour M.T., Brown S.R., Middleton G., et al. Panitumumab and irinotecan versus irinotecan alone for patients with KRAS wild-type, fluorouracil-resistant advanced colorectal cancer (PICCOLO): a prospectively stratified randomised trial. Lancet Oncol 2013, 14:749-759.
-
(2013)
Lancet Oncol
, vol.14
, pp. 749-759
-
-
Seymour, M.T.1
Brown, S.R.2
Middleton, G.3
-
16
-
-
84877087305
-
Massively parallel tumor multigene sequencing to evaluate response to panitumumab in a randomized phase III study of metastatic colorectal cancer
-
Peeters M., Oliner K.S., Parker A., et al. Massively parallel tumor multigene sequencing to evaluate response to panitumumab in a randomized phase III study of metastatic colorectal cancer. Clin Cancer Res 2013, 19:1902-1912.
-
(2013)
Clin Cancer Res
, vol.19
, pp. 1902-1912
-
-
Peeters, M.1
Oliner, K.S.2
Parker, A.3
-
17
-
-
84907023716
-
Treatment outcome according to tumor RAS mutation status in CRYSTAL study patients with metastatic colorectal cancer (mCRC) randomized to FOLFIRI with/without cetuximab
-
suppl
-
Ciardiello F., Lenz H.J., Kohne C.H., et al. Treatment outcome according to tumor RAS mutation status in CRYSTAL study patients with metastatic colorectal cancer (mCRC) randomized to FOLFIRI with/without cetuximab. J Clin Oncol 2014, 32(5s). (suppl; abstr 3506).
-
(2014)
J Clin Oncol
, vol.32
, Issue.5 S
-
-
Ciardiello, F.1
Lenz, H.J.2
Kohne, C.H.3
-
18
-
-
84901777464
-
Analysis of KRAS/NRAS mutations in phase 3 study 20050181 of panitumumab (pmab) plus FOLFIRI versus FOLFIRI for second-line treatment (tx) of metastatic colorectal cancer (mCRC)
-
suppl
-
Peeters M., Oliner K.S., Price T.J., et al. Analysis of KRAS/NRAS mutations in phase 3 study 20050181 of panitumumab (pmab) plus FOLFIRI versus FOLFIRI for second-line treatment (tx) of metastatic colorectal cancer (mCRC). J Clin Oncol 2014, 32(5s). (suppl; abstr LBA387).
-
(2014)
J Clin Oncol
, vol.32
, Issue.5 S
-
-
Peeters, M.1
Oliner, K.S.2
Price, T.J.3
-
19
-
-
84942203693
-
-
The summary for product characteristics for cetuximab
-
The summary for product characteristics for cetuximab available at: 〈http://www.ema.europa.eu/ema/index.jsp?curl=pages/medicines/human/medicines/000558/human_med_000769.jsp&mid=WC0b01ac058001d124〉.
-
-
-
-
20
-
-
84942203694
-
-
The summary for product characteristics for panitumumab
-
The summary for product characteristics for panitumumab available at: 〈http://www.ema.europa.eu/ema/index.jsp?curl=pages/medicines/human/medicines/000741/human_med_001128.jsp&mid=WC0b01ac058001d124〉.
-
-
-
-
21
-
-
0029914622
-
Assessing the quality of reports of randomized clinical trials: is blinding necessary?
-
Jadad A.R., Moore R.A., Carroll D., et al. Assessing the quality of reports of randomized clinical trials: is blinding necessary?. Control Clin Trials 1996, 17:1-12.
-
(1996)
Control Clin Trials
, vol.17
, pp. 1-12
-
-
Jadad, A.R.1
Moore, R.A.2
Carroll, D.3
-
22
-
-
69449100622
-
Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement
-
Moher D., Liberati A., Tetzlaff J., et al. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. BMJ 2009, 339:b2535. PRISMA Group.
-
(2009)
BMJ
, vol.339
, pp. b2535
-
-
Moher, D.1
Liberati, A.2
Tetzlaff, J.3
-
23
-
-
0023886868
-
Calculating confidence intervals for relative risks (odds ratios) and standardised ratios and rates
-
Morris J.A., Gardner M.J. Calculating confidence intervals for relative risks (odds ratios) and standardised ratios and rates. Br Med J (Clin Res Ed) 1988, 296:313-1316.
-
(1988)
Br Med J (Clin Res Ed)
, vol.296
, pp. 313-1316
-
-
Morris, J.A.1
Gardner, M.J.2
-
24
-
-
0041876133
-
Measuring inconsistency in meta-analyses
-
Higgins J.P., Thompson S.G., Deeks J.J., et al. Measuring inconsistency in meta-analyses. BMJ 2003, 327:557-560.
-
(2003)
BMJ
, vol.327
, pp. 557-560
-
-
Higgins, J.P.1
Thompson, S.G.2
Deeks, J.J.3
-
26
-
-
84888358440
-
-
The Cochrane Collaboration, The Nordic Cochrane Centre, Copenhagen
-
Review Manager (RevMan) [Computer program]. Version 5.2 2012, The Cochrane Collaboration, The Nordic Cochrane Centre, Copenhagen, Available at: 〈http://ims.cochrane.org/revman/download〉.
-
(2012)
[Computer program]. Version 5.2
-
-
-
27
-
-
79959337678
-
Addition of cetuximab to oxaliplatin-based first-line combination chemotherapy for treatment of advanced colorectal cancer: results of the randomised phase 3 MRC COIN trial
-
Maughan T.S., Adams R.A., Smith C.G., et al. Addition of cetuximab to oxaliplatin-based first-line combination chemotherapy for treatment of advanced colorectal cancer: results of the randomised phase 3 MRC COIN trial. Lancet 2011, 377:2103-2114.
-
(2011)
Lancet
, vol.377
, pp. 2103-2114
-
-
Maughan, T.S.1
Adams, R.A.2
Smith, C.G.3
-
28
-
-
84907023716
-
Treatment outcome according to tumor RAS mutation status in OPUS study patients with metastatic colorectal cancer (mCRC) randomized to FOLFOX4 with/without cetuximab
-
suppl
-
Bokemeyer C., Kohne C.H., Ciardiello F., et al. Treatment outcome according to tumor RAS mutation status in OPUS study patients with metastatic colorectal cancer (mCRC) randomized to FOLFOX4 with/without cetuximab. J Clin Oncol 2014, 32(5s). (suppl; abstr 3505).
-
(2014)
J Clin Oncol
, vol.32
, Issue.5 S
-
-
Bokemeyer, C.1
Kohne, C.H.2
Ciardiello, F.3
-
29
-
-
84937204003
-
CALGB/SWOG 80405: PHASE III trial of irinotecan/5-FU/leucovorin (FOLFIRI) or oxaliplatin/5-FU/leucovorin (mFOLFOX6) with bevacizumab (BV) or cetuximab (CET) for patients (pts) with expanded ras analyses untreated metastatic adenocarcinoma of the colon or rectum (MCRC)
-
suppl
-
Lenz H., Niedzwiecki D., Innocenti F., et al. CALGB/SWOG 80405: PHASE III trial of irinotecan/5-FU/leucovorin (FOLFIRI) or oxaliplatin/5-FU/leucovorin (mFOLFOX6) with bevacizumab (BV) or cetuximab (CET) for patients (pts) with expanded ras analyses untreated metastatic adenocarcinoma of the colon or rectum (MCRC). Ann Oncol 2014, 25(4s). (suppl; abstr 501O).
-
(2014)
Ann Oncol
, vol.25
, Issue.4 S
-
-
Lenz, H.1
Niedzwiecki, D.2
Innocenti, F.3
-
30
-
-
84923199426
-
Independent radiological evaluation of objective response rate, early tumor shrinkage, and depth of response in FIRE-3 (AIO KRK-0306) in the final RAS evaluable population
-
suppl
-
Stintzing F., Modest D.P., Fischer von Weikersthal L., et al. Independent radiological evaluation of objective response rate, early tumor shrinkage, and depth of response in FIRE-3 (AIO KRK-0306) in the final RAS evaluable population. Ann Oncol 2014, 25(4s). (suppl; abstr LBA11).
-
(2014)
Ann Oncol
, vol.25
, Issue.4 S
-
-
Stintzing, F.1
Modest, D.P.2
Fischer von Weikersthal, L.3
-
31
-
-
0035869407
-
Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2
-
Slamon D.J., Leyland-Jones B., Shak S., et al. Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2. N Engl J Med 2001, 344:783-792.
-
(2001)
N Engl J Med
, vol.344
, pp. 783-792
-
-
Slamon, D.J.1
Leyland-Jones, B.2
Shak, S.3
-
32
-
-
84862914692
-
Pertuzumab plus trastuzumab plus docetaxel for metastatic breast cancer
-
Baselga J., Cortés J., Kim S.B., et al. Pertuzumab plus trastuzumab plus docetaxel for metastatic breast cancer. N Engl J Med 2012, 366:109-119.
-
(2012)
N Engl J Med
, vol.366
, pp. 109-119
-
-
Baselga, J.1
Cortés, J.2
Kim, S.B.3
-
33
-
-
84857414572
-
Efficacy of EGFR tyrosine kinase inhibitors in patients with EGFR-mutated non-small-cell lung cancer: a meta-analysis of 13 randomized trials
-
Petrelli F., Borgonovo K., Cabiddu M., et al. Efficacy of EGFR tyrosine kinase inhibitors in patients with EGFR-mutated non-small-cell lung cancer: a meta-analysis of 13 randomized trials. Clin Lung Cancer 2012, 13:107-114.
-
(2012)
Clin Lung Cancer
, vol.13
, pp. 107-114
-
-
Petrelli, F.1
Borgonovo, K.2
Cabiddu, M.3
-
34
-
-
84906221716
-
First-line crizotinib versus pemetrexed-cisplatin or pemetrexed-carboplatin in patients (pts) with advanced ALK-positive non-squamous non-small cell lung cancer (NSCLC): results of a phase III study (PROFILE 1014)
-
suppl
-
Mok T., Kim D.W., Wu Y.L., et al. First-line crizotinib versus pemetrexed-cisplatin or pemetrexed-carboplatin in patients (pts) with advanced ALK-positive non-squamous non-small cell lung cancer (NSCLC): results of a phase III study (PROFILE 1014). J Clin Oncol 2014, 32(5s). (suppl; abstr 8002).
-
(2014)
J Clin Oncol
, vol.32
, Issue.5 S
-
-
Mok, T.1
Kim, D.W.2
Wu, Y.L.3
-
35
-
-
79959795786
-
Improved survival with vemurafenib in melanoma with BRAF V600E mutation
-
Chapman P.B., Hauschild A., Robert C., et al. Improved survival with vemurafenib in melanoma with BRAF V600E mutation. N Engl J Med 2011, 364:2507-2516.
-
(2011)
N Engl J Med
, vol.364
, pp. 2507-2516
-
-
Chapman, P.B.1
Hauschild, A.2
Robert, C.3
-
36
-
-
84929141867
-
Extended RAS mutations and anti-EGFR monoclonal antibody survival benefit in metastatic colorectal cancer: a meta-analysis of randomized, controlled trials
-
Sorich M.J., Wiese M.D., Rowland A., et al. Extended RAS mutations and anti-EGFR monoclonal antibody survival benefit in metastatic colorectal cancer: a meta-analysis of randomized, controlled trials. Ann Oncol. 2015, 26:13-21.
-
(2015)
Ann Oncol.
, vol.26
, pp. 13-21
-
-
Sorich, M.J.1
Wiese, M.D.2
Rowland, A.3
-
37
-
-
58749087713
-
Toxicity associated with combination oxaliplatin plus fluoropyrimidine with or without cetuximab in the MRC COIN trial experience
-
Adams R.A., Meade A.M., Madi A., et al. Toxicity associated with combination oxaliplatin plus fluoropyrimidine with or without cetuximab in the MRC COIN trial experience. Br J Cancer 2009, 100:251-258.
-
(2009)
Br J Cancer
, vol.100
, pp. 251-258
-
-
Adams, R.A.1
Meade, A.M.2
Madi, A.3
-
38
-
-
84861656612
-
Does anti-EGFR therapy improve outcome in advanced colorectal cancer?. A systematic review and meta-analysis
-
Vale C.L., Tierney J.F., Fisher D., et al. Does anti-EGFR therapy improve outcome in advanced colorectal cancer?. A systematic review and meta-analysis. Cancer Treat Rev 2012, 38:618-625.
-
(2012)
Cancer Treat Rev
, vol.38
, pp. 618-625
-
-
Vale, C.L.1
Tierney, J.F.2
Fisher, D.3
-
39
-
-
84911474269
-
Metastatic colorectal cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up
-
Van Cutsem E., Cervantes A., Nordlinger B., et al. Metastatic colorectal cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Ann Oncol 2014, 25(3s suppl.).
-
(2014)
Ann Oncol
, vol.25
, Issue.3 S SUPPL.
-
-
Van Cutsem, E.1
Cervantes, A.2
Nordlinger, B.3
-
40
-
-
84884700039
-
Bevacizumab plus capecitabine versus capecitabine alone in elderly patients with previously untreated metastatic colorectal cancer (AVEX): an open-label, randomised phase 3 trial
-
Cunningham D., Lang I., Marcuello E., et al. Bevacizumab plus capecitabine versus capecitabine alone in elderly patients with previously untreated metastatic colorectal cancer (AVEX): an open-label, randomised phase 3 trial. Lancet Oncol 2013, 14:1077-1085.
-
(2013)
Lancet Oncol
, vol.14
, pp. 1077-1085
-
-
Cunningham, D.1
Lang, I.2
Marcuello, E.3
-
41
-
-
84908139591
-
Initial therapy with FOLFOXIRI and bevacizumab for metastatic colorectal cancer
-
Loupakis F., Cremolini C., Masi G., et al. Initial therapy with FOLFOXIRI and bevacizumab for metastatic colorectal cancer. N Engl J Med 2014, 371:1609-1618.
-
(2014)
N Engl J Med
, vol.371
, pp. 1609-1618
-
-
Loupakis, F.1
Cremolini, C.2
Masi, G.3
-
42
-
-
84861199721
-
Recommendations on management of EGFR inhibitor-induced skin toxicity: a systematic review
-
Baas J.M., Krens L.L., Guchelaar H.J., et al. Recommendations on management of EGFR inhibitor-induced skin toxicity: a systematic review. Cancer Treat Rev 2012, 38:505-514.
-
(2012)
Cancer Treat Rev
, vol.38
, pp. 505-514
-
-
Baas, J.M.1
Krens, L.L.2
Guchelaar, H.J.3
-
43
-
-
0034729931
-
Relation between tumour response to first-line chemotherapy and survival in advanced colorectal cancer: a meta-analysis-Meta-Analysis Group in Cancer
-
Buyse M., Thirion P., Carlson R.W., et al. Relation between tumour response to first-line chemotherapy and survival in advanced colorectal cancer: a meta-analysis-Meta-Analysis Group in Cancer. Lancet 2000, 356:373-378.
-
(2000)
Lancet
, vol.356
, pp. 373-378
-
-
Buyse, M.1
Thirion, P.2
Carlson, R.W.3
-
44
-
-
84860634396
-
PIK3CA exon 20 mutations as a potential biomarker for resistance to anti-EGFR monoclonal antibodies in KRAS wild-type metastatic colorectal cancer: a systematic review and meta-analysis
-
Mao C., Yang Z.Y., Hu X.F., et al. PIK3CA exon 20 mutations as a potential biomarker for resistance to anti-EGFR monoclonal antibodies in KRAS wild-type metastatic colorectal cancer: a systematic review and meta-analysis. Ann Oncol 2012, 23:1518-1525.
-
(2012)
Ann Oncol
, vol.23
, pp. 1518-1525
-
-
Mao, C.1
Yang, Z.Y.2
Hu, X.F.3
-
45
-
-
84878862323
-
Amplification of the MET receptor drives resistance to anti-EGFR therapies in colorectal cancer
-
Bardelli A., Corso S., Bertotti A., et al. Amplification of the MET receptor drives resistance to anti-EGFR therapies in colorectal cancer. Cancer Discov 2013, 3:658-673.
-
(2013)
Cancer Discov
, vol.3
, pp. 658-673
-
-
Bardelli, A.1
Corso, S.2
Bertotti, A.3
-
46
-
-
84862772839
-
A molecularly annotated platform of patient-derived xenografts ("xenopatients") identifies HER2 as an effective therapeutic target in cetuximab-resistant colorectal cancer
-
Bertotti A., Migliardi G., Galimi F., et al. A molecularly annotated platform of patient-derived xenografts ("xenopatients") identifies HER2 as an effective therapeutic target in cetuximab-resistant colorectal cancer. Cancer Discov 2011, 1:508-523.
-
(2011)
Cancer Discov
, vol.1
, pp. 508-523
-
-
Bertotti, A.1
Migliardi, G.2
Galimi, F.3
-
47
-
-
84898875151
-
Gain of ALK gene copy number may predict lack of benefit from anti-EGFR treatment in patients with advanced colorectal cancer and RAS-RAF-PI3KCA wild-type status
-
Pietrantonio F., Maggi C., Di Bartolomeo M., et al. Gain of ALK gene copy number may predict lack of benefit from anti-EGFR treatment in patients with advanced colorectal cancer and RAS-RAF-PI3KCA wild-type status. PLoS ONE 2014, 9:e92147.
-
(2014)
PLoS ONE
, vol.9
, pp. e92147
-
-
Pietrantonio, F.1
Maggi, C.2
Di Bartolomeo, M.3
|