The association of rs4753426 polymorphism in the melatonin receptor 1b (MTNR1B) gene and susceptibility to adolescent idiopathic scoliosis: A systematic review and meta-analysis

Pain Physician

Volumn 18, Issue 5, 2015, Pages 419-431

  Yang, Peng ^a   Liu, Hao ^a   Lin, Jun ^a   Yang, Huilin ^a  

^a THE FIRST AFFILIATED HOSPITAL OF SOOCHOW UNIVERSITY   (China)

Author keywords

Adolescent idiopathic scoliosis; Curve severity; Meta analysis; MTNR1B; Occurrence; Rs4753426; Single nucleotide polymorphism

Indexed keywords

MELATONIN 1 RECEPTOR; MELATONIN 2 RECEPTOR; MTNR1B PROTEIN, HUMAN;

ADOLESCENT IDIOPATHIC SCOLIOSIS; ALLELE; ETHNICITY; GENE; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENETIC SUSCEPTIBILITY; GENOTYPE; HUMAN; MELATONIN RECEPTOR 1B GENE; META ANALYSIS; POLYMERASE CHAIN REACTION; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; REVIEW; SCIENTIFIC LITERATURE; SINGLE NUCLEOTIDE POLYMORPHISM; SYSTEMATIC REVIEW; ADOLESCENT; ASIAN CONTINENTAL ANCESTRY GROUP; GENE FREQUENCY; GENETIC PREDISPOSITION; GENETICS; SCOLIOSIS;

ADOLESCENT; ASIAN CONTINENTAL ANCESTRY GROUP; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; HUMANS; POLYMORPHISM, GENETIC; RECEPTOR, MELATONIN, MT2; SCOLIOSIS;

EID: 84942085885     PISSN: 15333159     EISSN: 21501149     Source Type: Journal    
DOI: None     Document Type: Review

References (31)

1. Weinstein SL, Dolan LA, Cheng JC, Danielsson A, Morcuende JA. Adolescent idiopathic scoliosis. Lancet 2008; 371:1527-1537.
2. Lonstein JE. Spondylolisthesis in children. Cause, natural history, and management. Spine (Phila Pa 1976) 1999; 24:2640-2648.
3. Trobisch P, Suess O, Schwab F. Idiopathic scoliosis. Dtsch Arztebl Int 2010; 107:875-883, 884.
4. Lamartina C, Capuzzo A, Cecchinato R, Zerbi A, Berjano P. Adolescent idiopathic scoliosis surgery with patient-specific screw placement-guides. Eur Spine J 2014; 23:2765-2766.
5. Asher MA, Burton DC. Adolescent idiopathic scoliosis: Natural history and long term treatment effects. Scoliosis 2006; 1:2.
6. Rogala EJ, Drummond DS, Gurr J. Scoliosis: Incidence and natural history. A prospective epidemiological study. J Bone Joint Surg Am 1978; 60:173-176.
7. Lowe TG, Edgar M, Margulies JY, Miller NH, Raso VJ, Reinker KA, Rivard CH. Etiology of idiopathic scoliosis: current trends in research. J Bone Joint Surg Am 2000; 82-A:1157-1168.
8. Wei-Jun W, Xu S, Zhi-Wei W, Xu-Sheng Q, Zhen L, Yong Q. Abnormal anthropometric measurements and growth pattern in male adolescent idiopathic scoliosis. Eur Spine J 2012; 21:77-83.
9. Miller NH. Genetics of familial idiopathic scoliosis. Clin Orthop Relat Res 2007; 462:6-10.
10. Wise CA, Barnes R, Gillum J, Herring JA, Bowcock AM, Lovett M. Localization of susceptibility to familial idiopathic scoliosis. Spine (Phila Pa 1976) 2000; 25:2372-2380.
11. Hefti F. Pathogenesis and biomechanics of adolescent idiopathic scoliosis (AIS). J Child Orthop 2013; 7:17-24.
12. Wise CA, Barnes R, Gillum J, Herring JA, Bowcock AM, Lovett M. Localization of susceptibility to familial idiopathic scoliosis. Spine (Phila Pa 1976) 2000; 25:2372-2380.
13. Justice CM, Miller NH, Marosy B, Zhang J, Wilson AF. Familial idiopathic scoliosis: Evidence of an X-linked susceptibility locus. Spine (Phila Pa 1976) 2003; 28:589-594.
14. Chan V, Fong GC, Luk KD, Yip B, Lee MK, Wong MS, Lu DD, Chan TK. A genetic locus for adolescent idiopathic scoliosis linked to chromosome 19p13.3. Am J Hum Genet 2002; 71:401-406.
15. Miller NH, Justice CM, Marosy B, Doheny KF, Pugh E, Zhang J, Dietz HC, Wilson AF. Identification of candidate regions for familial idiopathic scoliosis. Spine (Phila Pa 1976) 2005; 30:1181-1187.
16. Lerner AB, Case JD, Takahashi Y. Isolation of melatonin and 5-methoxyindole-3-acetic acid from bovine pineal glands. J Biol Chem 1960; 235:1992-1997.
17. Thillard MJ. [Vertebral column deformities following epiphysectomy in the chick]. C R Hebd Seances Acad Sci 1959; 248:1238-1240.
18. von Gall C, Stehle JH, Weaver DR. Mammalian melatonin receptors: Molecular biology and signal transduction. Cell Tissue Res 2002; 309:151-162.
19. Morcuende JA, Minhas R, Dolan L, Stevens J, Beck J, Wang K, Weinstein SL, Sheffield V. Allelic variants of human melatonin 1A receptor in patients with familial adolescent idiopathic scoliosis. Spine (Phila Pa 1976) 2003; 28:2025-2028, 2029.
20. Qiu XS, Tang NL, Yeung HY, Lee KM, Hung VW, Ng BK, Ma SL, Kwok RH, Qin L, Qiu Y, Cheng JC. Melatonin receptor 1B (MTNR1B) gene polymorphism is associated with the occurrence of adolescent idiopathic scoliosis. Spine (Phila Pa 1976) 2007; 32:1748-1753.
21. Nelson LM, Ward K, Ogilvie JW. Genetic variants in melatonin synthesis and signaling pathway are not associated with adolescent idiopathic scoliosis. Spine (Phila Pa 1976) 2011; 36:37-40.
22. Takahashi Y, Matsumoto M, Karasugi T, Watanabe K, Chiba K, Kawakami N, Tsuji T, Uno K, Suzuki T, Ito M, Sudo H, Minami S, Kotani T, Kono K, Yanagida H. Lack of association between adolescent idiopathic scoliosis and previously reported single nucleotide polymorphisms in MATN1, MTNR1B, TPH1, and IGF1 in a Japanese population.J Orthop Res 2011; 29:1055-1058.
23. Qiu XS, Tang NL, Yeung HY, Qiu Y, Qin L, Lee KM, Cheng JC. The role of melatonin receptor 1B gene (MTNR1B) in adolescent idiopathic scoliosis--a genetic association study.Stud Health Technol Inform 2006; 123:3-8.
24. Salanti G, Sanderson S, Higgins JP. Obstacles and opportunities in meta-analysis of genetic association studies. Genet Med 2005; 7:13-20.
25. Moher D, Liberati A, Tetzlaff J, Altman DG. Preferred reporting items for systematic reviews and meta-analyses: The PRISMA statement. BMJ 2009; 339:b2535.
26. Ioannidis JP, Trikalinos TA. The appropriateness of asymmetry tests for publication bias in meta-analyses: A large survey. CMAJ 2007; 176:1091-1096.
27. Morocz M, Czibula A, Grozer ZB, Szecsenyi A, Almos PZ, Rasko I, Illes T. Association study of BMP4, IL6, Leptin, MMP3, and MTNR1B gene promoter polymorphisms and adolescent idiopathic scoliosis.Spine (Phila Pa 1976) 2011; 36:E123-E130.
28. Qiu XS, Deng LS, Yang XE, Zheng ZY, Qiu Y. The promoter polynmrphisms of melatonin receptor 1 B gene in adolescent idiopathic scoliosis. Chin J Pediatr Surg 2009; 30:869-872.
29. Oyama J, Murai I, Kanazawa K, Machida M. Bipedal ambulation induces experimental scoliosis in C57BL/6J mice with reduced plasma and pineal melatonin levels. J Pineal Res 2006; 40:219-224.
30. Xu L, Qiu X, Sun X, Mao S, Liu Z, Qiao J, Qiu Y. Potential genetic markers predicting the outcome of brace treatment in patients with adolescent idiopathic scoliosis.Eur Spine J 2011; 20:1757-1764.
31. Juni P, Holenstein F, Sterne J, Bartlett C, Egger M. Direction and impact of language bias in meta-analyses of controlled trials: Empirical study. Int J Epidemiol 2002; 31:115-123.