Hypoxia-mediated cancer stem cells in pseudopalisades with activation of hypoxia-inducible factor-1α/Akt axis in glioblastoma

Human Pathology

Volumn 46, Issue 10, 2015, Pages 1496-1505

  Inukai, Madoka ^a,b   Hara, Atsuko ^a   Yasui, Yoshie ^b   Kumabe, Toshihiro ^b   Matsumoto, Toshihide ^a   Saegusa, Makoto ^a  

^a KITASATO UNIVERSITY   (Japan)

^b KITASATO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Akt; Cancer stem cell; Glioblastoma; HIF 1 ; Pseudopalisade

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; ALDEHYDE DEHYDROGENASE; CD133 ANTIGEN; COBALT CHLORIDE; CYCLIN DEPENDENT KINASE INHIBITOR 1B; GLUCOSE TRANSPORTER 1; HERMES ANTIGEN; HYPOXIA INDUCIBLE FACTOR 1ALPHA; PROTEIN BCL 2; PROTEIN KINASE B; SURVIVIN; TRANSCRIPTION FACTOR SOX2; HIF1A PROTEIN, HUMAN;

ADOLESCENT; ADULT; AGED; APOPTOSIS; ARTICLE; ASTROCYTOMA; ASTROCYTOMA CELL LINE; CANCER STEM CELL; CELL HYPOXIA; CELL POPULATION; CHILD; CONTROLLED STUDY; EXPOSURE; FEMALE; GLIOBLASTOMA; GLIOMA CELL; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; PROTEIN EXPRESSION; TUMOR NECROSIS; TUMOR PSEUDOPALISADE; BRAIN TUMOR; METABOLISM; PATHOLOGY; PHYSIOLOGY; PRESCHOOL CHILD; SIGNAL TRANSDUCTION; STEM CELL NICHE; TUMOR CELL LINE; TUNEL ASSAY; WESTERN BLOTTING; YOUNG ADULT;

ADOLESCENT; ADULT; AGED; BLOTTING, WESTERN; BRAIN NEOPLASMS; CELL HYPOXIA; CELL LINE, TUMOR; CHILD; CHILD, PRESCHOOL; FEMALE; GLIOBLASTOMA; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; IMMUNOHISTOCHEMISTRY; IN SITU NICK-END LABELING; MALE; MIDDLE AGED; NEOPLASTIC STEM CELLS; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; STEM CELL NICHE; YOUNG ADULT;

EID: 84941935298     PISSN: 00468177     EISSN: 15328392     Source Type: Journal    
DOI: 10.1016/j.humpath.2015.06.008     Document Type: Article

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