Pyridoxamine protects proteins from damage by hypohalous acids in vitro and in vivo

Free Radical Biology and Medicine

Volumn 89, Issue , 2015, Pages 83-90

  Madu, Hartman ^a,c   Avance, Josh ^a,d   Chetyrkin, Sergei ^a   Darris, Carl ^a   Rose, Kristie Lindsey ^b   Sanchez, Otto A ^a,e   Hudson, Billy ^a,b   Voziyan, Paul ^a  

^a VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

^b VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c MEHARRY MEDICAL COLLEGE   (United States)

^d BEREA COLLEGE   (United States)

^e UNIVERSITY OF MINNESOTA   (United States)

Author keywords

Diabetes; Freeradicals; Hypobromous acid; Hypochlorous acid; Nephropathy; Posttranslational modifications; Protein halogenation; Pyridoxamine

Indexed keywords

COLLAGEN TYPE 4; HYPOCHLOROUS ACID; PYRIDOXAMINE; BROMATE; HYPOBROMOUS ACID; OXIDIZING AGENT; VITAMIN B COMPLEX;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DIABETIC NEPHROPATHY; DRUG MECHANISM; IN VITRO STUDY; IN VIVO STUDY; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN MODIFICATION; PROTEIN STRUCTURE; RAT; AMINO ACID SEQUENCE; ANIMAL; CHEMISTRY; DIABETES MELLITUS, EXPERIMENTAL; DRUG EFFECTS; HUMAN; KIDNEY; LIQUID CHROMATOGRAPHY; METABOLISM; MOLECULAR GENETICS; OXIDATION REDUCTION REACTION; PATHOLOGY; SPRAGUE DAWLEY RAT; TANDEM MASS SPECTROMETRY;

AMINO ACID SEQUENCE; ANIMALS; BROMATES; CHROMATOGRAPHY, LIQUID; COLLAGEN TYPE IV; DIABETES MELLITUS, EXPERIMENTAL; HUMANS; HYPOCHLOROUS ACID; IN VITRO TECHNIQUES; KIDNEY; MALE; MOLECULAR SEQUENCE DATA; OXIDANTS; OXIDATION-REDUCTION; PROTEOLYSIS; PYRIDOXAMINE; RATS; RATS, SPRAGUE-DAWLEY; TANDEM MASS SPECTROMETRY; VITAMIN B COMPLEX;

EID: 84941920413     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2015.07.001     Document Type: Article

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