3,6-dihydroxyflavone suppresses breast carcinogenesis by epigenetically regulating miR-34a and miR-21

Cancer Prevention Research

Volumn 8, Issue 6, 2015, Pages 509-517

  Peng, Xiaoli ^a,b   Chang, Hui ^a   Gu, Yeyun ^a   Chen, Junli ^a   Yi, Long ^a   Xie, Qi ^a   Zhu, Jundong ^a   Zhang, Qianyong ^a   Mi, Mantian ^a  

^a THIRD MILITARY MEDICAL UNIVERSITY   (China)

^b CHENGDU MEDICAL COLLEGE   (China)

Author keywords

[No Author keywords available]

Indexed keywords

3,6 DIHYDROXYFLAVONE; ANTINEOPLASTIC AGENT; DNA METHYLTRANSFERASE 1; DNA METHYLTRANSFERASE INHIBITOR; FLAVONE DERIVATIVE; MAMMALIAN TARGET OF RAPAMYCIN; MICRORNA 21; MICRORNA 34A; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; UNCLASSIFIED DRUG; 3,6-DIHYDROXYFLAVONE; DNA (CYTOSINE 5) METHYLTRANSFERASE; DNA (CYTOSINE-5-)-METHYLTRANSFERASE 1; FLAVONOID; MESSENGER RNA; MICRORNA; MIRN21 MICRORNA, HUMAN; MIRN34 MICRORNA, HUMAN; MTOR PROTEIN, HUMAN; TARGET OF RAPAMYCIN KINASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BREAST CARCINOGENESIS; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVATION; EPIGENETICS; FEMALE; GENE CONTROL; GENE OVEREXPRESSION; HISTONE MODIFICATION; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; MOLECULAR DOCKING; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION; UPREGULATION; ANIMAL; ANTAGONISTS AND INHIBITORS; APOPTOSIS; BAGG ALBINO MOUSE; BREAST NEOPLASMS; CELL PROLIFERATION; CELL TRANSFORMATION; DNA METHYLATION; DRUG EFFECTS; DRUG SCREENING; ENZYME IMMUNOASSAY; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MOUSE; NUDE MOUSE; PATHOLOGY; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPRAGUE DAWLEY RAT; TUMOR CELL CULTURE; WESTERN BLOTTING;

ANIMALS; APOPTOSIS; BLOTTING, WESTERN; BREAST NEOPLASMS; CELL PROLIFERATION; CELL TRANSFORMATION, NEOPLASTIC; DNA (CYTOSINE-5-)-METHYLTRANSFERASE; DNA METHYLATION; EPIGENOMICS; FEMALE; FLAVONOIDS; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; IMMUNOENZYME TECHNIQUES; MICE; MICE, INBRED BALB C; MICE, NUDE; MICRORNAS; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, SPRAGUE-DAWLEY; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SIGNAL TRANSDUCTION; TOR SERINE-THREONINE KINASES; TUMOR CELLS, CULTURED; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84941793282     PISSN: 19406207     EISSN: 19406215     Source Type: Journal    
DOI: 10.1158/1940-6207.CAPR-14-0357     Document Type: Article

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